myc-Raptor Citations (16)
Originally described in: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM Curr Biol 2004 Jul 27;14(14):1296-302. PubMed Journal
Articles Citing myc-Raptor
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Primary cilia regulate mTORC1 activity and cell size through Lkb1. Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Godel M, Muller K, Herbst M, Hornung M, Doerken M, Kottgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW. Nat Cell Biol. 2010 Nov;12(11):1115-22. doi: 10.1038/ncb2117. Epub 2010 Oct 24. PubMed |
JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice. Fujishita T, Aoki M, Taketo MM. Gastroenterology. 2011 May;140(5):1556-63.e6. doi: 10.1053/j.gastro.2011.02.007. Epub 2011 Feb 12. PubMed |
Regulation of mTORC1 complex assembly and signaling by GRp58/ERp57. Ramirez-Rangel I, Bracho-Valdes I, Vazquez-Macias A, Carretero-Ortega J, Reyes-Cruz G, Vazquez-Prado J. Mol Cell Biol. 2011 Apr;31(8):1657-71. doi: 10.1128/MCB.00824-10. Epub 2011 Feb 14. PubMed |
The identification of raptor as a substrate for p44/42 MAPK. Langlais P, Yi Z, Mandarino LJ. Endocrinology. 2011 Apr;152(4):1264-73. doi: 10.1210/en.2010-1271. Epub 2011 Feb 15. PubMed |
ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding. Dunlop EA, Hunt DK, Acosta-Jaquez HA, Fingar DC, Tee AR. Autophagy. 2011 Jul;7(7):737-47. Epub 2011 Jul 1. PubMed |
Large FK506-binding proteins shape the pharmacology of rapamycin. Marz AM, Fabian AK, Kozany C, Bracher A, Hausch F. Mol Cell Biol. 2013 Apr;33(7):1357-67. doi: 10.1128/MCB.00678-12. Epub 2013 Jan 28. PubMed |
Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L. Cell. 2013 Feb 14;152(4):791-805. doi: 10.1016/j.cell.2013.01.033. PubMed |
Gbetagamma interacts with mTOR and promotes its activation. Robles-Molina E, Dionisio-Vicuna M, Guzman-Hernandez ML, Reyes-Cruz G, Vazquez-Prado J. Biochem Biophys Res Commun. 2014 Feb 7;444(2):218-23. doi: 10.1016/j.bbrc.2014.01.044. Epub 2014 Jan 22. PubMed |
The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR. Verma R, Marchese A. J Biol Chem. 2015 Mar 13;290(11):6810-24. doi: 10.1074/jbc.M114.606699. Epub 2015 Jan 20. PubMed |
The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity. Hao F, Itoh T, Morita E, Shirahama-Noda K, Yoshimori T, Noda T. FEBS Lett. 2016 Jan;590(1):161-73. doi: 10.1002/1873-3468.12048. Epub 2015 Dec 31. PubMed |
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Carbonneau M, M Gagne L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot ME, Mallette FA. Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700. PubMed |
Dynamics of mTORC1 activation in response to amino acids. Manifava M, Smith M, Rotondo S, Walker S, Niewczas I, Zoncu R, Clark J, Ktistakis NT. Elife. 2016 Oct 11;5. pii: e19960. doi: 10.7554/eLife.19960. PubMed |
Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1. Liu D, Ceddia RP, Collins S. Mol Metab. 2018 Mar;9:192-198. doi: 10.1016/j.molmet.2017.12.017. Epub 2018 Jan 17. PubMed |
mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy. Seo SU, Woo SM, Lee HS, Kim SH, Min KJ, Kwon TK. Oncogene. 2018 Sep;37(38):5205-5220. doi: 10.1038/s41388-018-0345-6. Epub 2018 May 30. PubMed |
mTOR modulates resistance to gemcitabine in lung cancer in an MTORC2 dependent mechanism. Chawsheen MA, Dash PR. Cell Signal. 2021 May;81:109934. doi: 10.1016/j.cellsig.2021.109934. Epub 2021 Feb 3. PubMed |
VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma. Ganner A, Gehrke C, Klein M, Thegtmeier L, Matulenski T, Wingendorf L, Wang L, Pilz F, Greidl L, Meid L, Kotsis F, Walz G, Frew IJ, Neumann-Haefelin E. Sci Rep. 2021 Jul 21;11(1):14827. doi: 10.1038/s41598-021-94132-5. PubMed |
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