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pLenti-gRNA-puro Citations (2)

Originally described in: Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9.
Sapozhnikov DM, Szyf M Nat Commun. 2021 Sep 29;12(1):5711. doi: 10.1038/s41467-021-25991-9.
PubMed Journal

Articles Citing pLenti-gRNA-puro

Articles
The PROTECTOR strategy employs dCas orthologs to sterically shield off-target sites from CRISPR/Cas activity. Sapozhnikov DM, Szyf M. Sci Rep. 2023 Feb 9;13(1):2280. doi: 10.1038/s41598-023-29332-2. PubMed

Associated Plasmids

Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition. Mahmood N, Arakelian A, Szyf M, Rabbani SA. Exp Mol Med. 2024 Apr;56(4):959-974. doi: 10.1038/s12276-024-01205-2. Epub 2024 Apr 1. PubMed

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