pLKO.1 shSCR Citations (33)

Originally described in: Flap endonuclease 1 contributes to telomere stability.
Saharia A, Guittat L, Crocker S, Lim A, Steffen M, Kulkarni S, Stewart SA Curr Biol. 2008 Apr 8. 18(7):496-500. PubMed Journal

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Articles Citing pLKO.1 shSCR

Articles
The role of Pea3 group transcription factors in esophageal squamous cell carcinoma. Yuen HF, McCrudden CM, Chan KK, Chan YP, Wong ML, Chan KY, Khoo US, Law S, Srivastava G, Lappin TR, Chan KW, El-Tanani M. Am J Pathol. 2011 Aug;179(2):992-1003. doi: 10.1016/j.ajpath.2011.04.004. Epub 2011 May 31. PubMed
Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1. Rizzolio F, Lucchetti C, Caligiuri I, Marchesi I, Caputo M, Klein-Szanto AJ, Bagella L, Castronovo M, Giordano A. Cell Death Differ. 2012 Jul;19(7):1152-61. doi: 10.1038/cdd.2011.202. Epub 2012 Feb 10. PubMed
Combinatorial use of bone morphogenetic protein 6, noggin and SOST significantly predicts cancer progression. Yuen HF, McCrudden CM, Grills C, Zhang SD, Huang YH, Chan KK, Chan YP, Wong ML, Law S, Srivastava G, Fennell DA, Dickson G, El-Tanani M, Chan KW. Cancer Sci. 2012 Jun;103(6):1145-54. doi: 10.1111/j.1349-7006.2012.02252.x. Epub 2012 Apr 3. PubMed
Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editing. Capshew CR, Dusenbury KL, Hundley HA. Nucleic Acids Res. 2012 Sep 1;40(17):8637-45. Epub 2012 Jun 25. PubMed
Androgen receptor serine 81 mediates Pin1 interaction and activity. La Montagna R, Caligiuri I, Maranta P, Lucchetti C, Esposito L, Paggi MG, Toffoli G, Rizzolio F, Giordano A. Cell Cycle. 2012 Sep 15;11(18):3415-20. doi: 10.4161/cc.21730. Epub 2012 Aug 16. PubMed
The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation. Marchesi I, Fiorentino FP, Rizzolio F, Giordano A, Bagella L. Cell Cycle. 2012 Oct 15;11(20):3828-36. doi: 10.4161/cc.22025. Epub 2012 Sep 14. PubMed
High-mobility group box 2 (HMGB2) modulates radioresponse and is downregulated by p53 in colorectal cancer cell. Shin YJ, Kim MS, Kim MS, Lee J, Kang M, Jeong JH. Cancer Biol Ther. 2013 Mar;14(3):213-21. doi: 10.4161/cbt.23292. Epub 2012 Dec 19. PubMed
The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor alpha in breast cancer. Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. PLoS One. 2013;8(2):e55355. doi: 10.1371/journal.pone.0055355. Epub 2013 Feb 4. PubMed
pRb controls estrogen receptor alpha protein stability and activity. Caligiuri I, Toffoli G, Giordano A, Rizzolio F. Oncotarget. 2013 Jun;4(6):875-83. PubMed
Chromosomal instability and telomere shortening in long-term culture of hematopoietic stem cells: insights from a cell culture model of RPS14 haploinsufficiency. Thomay K, Schienke A, Vajen B, Modlich U, Schambach A, Hofmann W, Schlegelberger B, Gohring G. Cytogenet Genome Res. 2014;142(1):14-20. doi: 10.1159/000356096. Epub 2013 Oct 26. PubMed
microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites. Offer SM, Butterfield GL, Jerde CR, Fossum CC, Wegner NJ, Diasio RB. Mol Cancer Ther. 2014 Mar;13(3):742-51. doi: 10.1158/1535-7163.MCT-13-0878. Epub 2014 Jan 8. PubMed
deltaNp63 has a role in maintaining epithelial integrity in airway epithelium. Arason AJ, Jonsdottir HR, Halldorsson S, Benediktsdottir BE, Bergthorsson JT, Ingthorsson S, Baldursson O, Sinha S, Gudjonsson T, Magnusson MK. PLoS One. 2014 Feb 12;9(2):e88683. doi: 10.1371/journal.pone.0088683. eCollection 2014. PubMed
HIF2alpha-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC. Cancer Discov. 2015 Jun;5(6):652-67. doi: 10.1158/2159-8290.CD-14-1507. Epub 2015 Mar 31. PubMed
MicroRNA-200c-141 and Np63 are required for breast epithelial differentiation and branching morphogenesis. Hilmarsdottir B, Briem E, Sigurdsson V, Franzdottir SR, Ringner M, Arason AJ, Bergthorsson JT, Magnusson MK, Gudjonsson T. Dev Biol. 2015 Jul 15;403(2):150-61. doi: 10.1016/j.ydbio.2015.05.007. Epub 2015 May 9. PubMed
Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in culture. Jonsdottir HR, Arason AJ, Palsson R, Franzdottir SR, Gudbjartsson T, Isaksson HJ, Gudmundsson G, Gudjonsson T, Magnusson MK. Lab Invest. 2015 Dec;95(12):1418-28. doi: 10.1038/labinvest.2015.114. Epub 2015 Sep 21. PubMed
The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Pai P, Rachagani S, Lakshmanan I, Macha MA, Sheinin Y, Smith LM, Ponnusamy MP, Batra SK. Mol Oncol. 2016 Feb;10(2):224-39. doi: 10.1016/j.molonc.2015.10.005. Epub 2015 Oct 19. PubMed
Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes. Salari A, Thomay K, Himmler K, Vajen B, Schienke A, Hagedorn M, Ebersold J, Kreipe HH, Kruger A, Schambach A, Schlegelberger B, Gohring G. Cancer Genet. 2016 Jun;209(6):258-66. doi: 10.1016/j.cancergen.2016.04.004. Epub 2016 Apr 22. PubMed
MUC4 is negatively regulated through the Wnt/beta-catenin pathway via the Notch effector Hath1 in colorectal cancer. Pai P, Rachagani S, Dhawan P, Sheinin YM, Macha MA, Qazi AK, Chugh S, Ponnusamy MP, Mallya K, Pothuraju R, Batra SK. Genes Cancer. 2016 May;7(5-6):154-68. doi: 10.18632/genesandcancer.108. PubMed
Requirement of Hsp105 in CoCl2-induced HIF-1alpha accumulation and transcriptional activation. Mikami H, Saito Y, Okamoto N, Kakihana A, Kuga T, Nakayama Y. Exp Cell Res. 2017 Mar 15;352(2):225-233. doi: 10.1016/j.yexcr.2017.02.004. Epub 2017 Feb 6. PubMed
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. PubMed
High Mobility Group Box 1 Influences HSV1716 Spread and Acts as an Adjuvant to Chemotherapy. Sprague L, Lee JM, Hutzen BJ, Wang PY, Chen CY, Conner J, Braidwood L, Cassady KA, Cripe TP. Viruses. 2018 Mar 15;10(3). pii: v10030132. doi: 10.3390/v10030132. PubMed
RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines. Pentimalli F, Forte IM, Esposito L, Indovina P, Iannuzzi CA, Alfano L, Costa C, Barone D, Rocco G, Giordano A. Oncogene. 2018 Jul;37(27):3657-3671. doi: 10.1038/s41388-018-0214-3. Epub 2018 Apr 2. PubMed
Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC. Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10. PubMed
Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation. Wakae K, Nishiyama T, Kondo S, Izuka T, Que L, Chen C, Kase K, Kitamura K, Mohiuddin M, Wang Z, Ahasan MM, Nakamura M, Fujiwara H, Yoshizaki T, Hosomochi K, Tajima A, Nakahara T, Kiyono T, Muramatsu M. Sci Rep. 2018 Jun 27;8(1):9745. doi: 10.1038/s41598-018-27930-z. PubMed
Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation. Ackerman D, Tumanov S, Qiu B, Michalopoulou E, Spata M, Azzam A, Xie H, Simon MC, Kamphorst JJ. Cell Rep. 2018 Sep 4;24(10):2596-2605.e5. doi: 10.1016/j.celrep.2018.08.015. PubMed
IL-1beta Inflammatory Cytokine-Induced TP63 Isoform NP63alpha Signaling Cascade Contributes to Cisplatin Resistance in Human Breast Cancer Cells. Mendoza-Rodriguez MG, Ayala-Sumuano JT, Garcia-Morales L, Zamudio-Meza H, Perez-Yepez EA, Meza I. Int J Mol Sci. 2019 Jan 11;20(2). pii: ijms20020270. doi: 10.3390/ijms20020270. PubMed
Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide. Forte IM, Indovina P, Iannuzzi CA, Cirillo D, Di Marzo D, Barone D, Capone F, Pentimalli F, Giordano A. Int J Oncol. 2019 Jun;54(6):2189-2199. doi: 10.3892/ijo.2019.4788. Epub 2019 Apr 16. PubMed
Gamma-Glutamyltransferase 1 Promotes Clear Cell Renal Cell Carcinoma Initiation and Progression. Bansal A, Sanchez DJ, Nimgaonkar V, Sanchez D, Riscal R, Skuli N, Simon MC. Mol Cancer Res. 2019 May 31. pii: 1541-7786.MCR-18-1204. doi: 10.1158/1541-7786.MCR-18-1204. PubMed
Hsp105alpha suppresses Adriamycin-induced cell death via nuclear localization signal-dependent nuclear accumulation. Yamane T, Saito Y, Teshima H, Hagino M, Kakihana A, Sato S, Shimada M, Kato Y, Kuga T, Yamagishi N, Nakayama Y. J Cell Biochem. 2019 Jun 7. doi: 10.1002/jcb.29062. PubMed
The mechano-sensitive response of beta1 integrin promotes SRC-positive late endosome recycling and activation of Yes-associated protein. Block MR, Brunner M, Ziegelmeyer T, Lallemand D, Pezet M, Chevalier G, Ronde P, Gauthier-Rouviere C, Wehrle-Haller B, Bouvard D. J Biol Chem. 2020 Jul 19. pii: RA120.013503. doi: 10.1074/jbc.RA120.013503. PubMed
Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma. Xie H, Song J, Godfrey J, Riscal R, Skuli N, Nissim I, Simon MC. Nat Metab. 2021 Mar;3(3):327-336. doi: 10.1038/s42255-021-00367-x. Epub 2021 Mar 23. PubMed
Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation. Fabra-Beser J, Alves Medeiros de Araujo J, Marques-Coelho D, Goff LA, Costa MR, Muller U, Gil-Sanz C. J Neurosci. 2021 Aug 18;41(33):6969-6986. doi: 10.1523/JNEUROSCI.2905-20.2021. Epub 2021 Jul 15. PubMed
Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition. Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E, Marques M, Crisan M, Mitro N, Santoro MM. Nat Metab. 2022 Jan;4(1):123-140. doi: 10.1038/s42255-021-00514-4. Epub 2022 Jan 27. PubMed

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