pGL3-NFAT luciferase Citations (36)
Originally described in: Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation.Clipstone NA, Crabtree GR Nature. 1992 Jun 25. 357(6380):695-7. PubMed Journal
Articles Citing pGL3-NFAT luciferase
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| Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc. Gajghate S, Hiyama A, Shah M, Sakai D, Anderson DG, Shapiro IM, Risbud MV. J Bone Miner Res. 2009 Jun;24(6):992-1001. doi: 10.1359/jbmr.090103. PubMed |
| Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc. Hiyama A, Gajghate S, Sakai D, Mochida J, Shapiro IM, Risbud MV. J Biol Chem. 2009 Apr 10;284(15):9824-34. doi: 10.1074/jbc.M807081200. Epub 2009 Jan 15. PubMed |
| A fluorescence-based assay to monitor transcriptional activity of NFAT in living cells. Rinne A, Blatter LA. J Physiol. 2010 Sep 1;588(Pt 17):3211-6. doi: 10.1113/jphysiol.2010.192419. Epub 2010 Jul 12. PubMed |
| RA-RAR-beta counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression. Puttagunta R, Schmandke A, Floriddia E, Gaub P, Fomin N, Ghyselinck NB, Di Giovanni S. J Cell Biol. 2011 Jun 27;193(7):1147-56. doi: 10.1083/jcb.201102066. Epub 2011 Jun 20. PubMed |
| Ovatodiolide Targets beta -Catenin Signaling in Suppressing Tumorigenesis and Overcoming Drug Resistance in Renal Cell Carcinoma. Ho JY, Hsu RJ, Wu CL, Chang WL, Cha TL, Yu DS, Yu CP. Evid Based Complement Alternat Med. 2013;2013:161628. doi: 10.1155/2013/161628. Epub 2013 May 26. PubMed |
| Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW, Tai TS, Tseng W, Chang HH, Grenningloh R, Miaw SC, Ho IC. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15776-81. doi: 10.1073/pnas.1304343110. Epub 2013 Sep 9. PubMed |
| The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma. Weissinger D, Tagscherer KE, Macher-Goppinger S, Haferkamp A, Wagener N, Roth W. Mol Cancer. 2013 Oct 10;12(1):120. doi: 10.1186/1476-4598-12-120. PubMed |
| Functional activities of mutant calcium-sensing receptors determine clinical presentations in patients with autosomal dominant hypocalcemia. Kinoshita Y, Hori M, Taguchi M, Watanabe S, Fukumoto S. J Clin Endocrinol Metab. 2014 Feb;99(2):E363-8. doi: 10.1210/jc.2013-3430. Epub 2013 Dec 2. PubMed |
| Tumor necrosis factor-alpha- and interleukin-1beta-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-kappaB axis: implications in inflammatory disc disease. Wang X, Wang H, Yang H, Li J, Cai Q, Shapiro IM, Risbud MV. Am J Pathol. 2014 Sep;184(9):2560-72. doi: 10.1016/j.ajpath.2014.06.006. Epub 2014 Jul 22. PubMed |
| Amplified lipid rafts of malignant cells constitute a target for inhibition of aberrantly active NFAT and melanoma tumor growth by the aminobisphosphonate zoledronic acid. Levin-Gromiko U, Koshelev V, Kushnir P, Fedida-Metula S, Voronov E, Fishman D. Carcinogenesis. 2014 Nov;35(11):2555-66. doi: 10.1093/carcin/bgu178. Epub 2014 Aug 20. PubMed |
| Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin. Strack J, Heni H, Gilsbach R, Hein L, Aktories K, Orth JH. MBio. 2014 Nov 11;5(6):e02190. doi: 10.1128/mBio.02190-14. PubMed |
| The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins. Imam H, Bano AS, Patel P, Holla P, Jameel S. Sci Rep. 2015 Mar 2;5:8639. doi: 10.1038/srep08639. PubMed |
| RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism. Garcia-Mariscal A, Peyrollier K, Basse A, Pedersen E, Ruhl R, van Hengel J, Brakebusch C. Small GTPases. 2016 Oct 18:1-12. PubMed |
| G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms. Gonzalez de Valdivia E, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF. J Biol Chem. 2017 Jun 16;292(24):9932-9943. doi: 10.1074/jbc.M116.765875. Epub 2017 Apr 27. PubMed |
| Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. Younan P, Iampietro M, Nishida A, Ramanathan P, Santos RI, Dutta M, Lubaki NM, Koup RA, Katze MG, Bukreyev A. MBio. 2017 Sep 26;8(5). pii: mBio.00845-17. doi: 10.1128/mBio.00845-17. PubMed |
| Src-family kinases negatively regulate NFAT signaling in resting human T cells. Baer A, Colon-Moran W, Xiang J, Stapleton JT, Bhattarai N. PLoS One. 2017 Oct 26;12(10):e0187123. doi: 10.1371/journal.pone.0187123. eCollection 2017. PubMed |
| CC-401 Promotes beta-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition. Abdolazimi Y, Zhao Z, Lee S, Xu H, Allegretti P, Horton TM, Yeh B, Moeller HP, Nichols RJ, McCutcheon D, Shalizi A, Smith M, Armstrong NA, Annes JP. Endocrinology. 2018 Sep 1;159(9):3143-3157. doi: 10.1210/en.2018-00083. PubMed |
| A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression. Kycia I, Wolford BN, Huyghe JR, Fuchsberger C, Vadlamudi S, Kursawe R, Welch RP, Albanus RD, Uyar A, Khetan S, Lawlor N, Bolisetty M, Mathur A, Kuusisto J, Laakso M, Ucar D, Mohlke KL, Boehnke M, Collins FS, Parker SCJ, Stitzel ML. Am J Hum Genet. 2018 Apr 5;102(4):620-635. doi: 10.1016/j.ajhg.2018.02.020. PubMed |
| Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways. Baer A, Colon-Moran W, Bhattarai N. Sci Rep. 2018 Jul 19;8(1):10910. doi: 10.1038/s41598-018-29355-0. PubMed |
| NHA2 promotes cyst development in an in vitro model of polycystic kidney disease. Prasad H, Dang DK, Kondapalli KC, Natarajan N, Cebotaru V, Rao R. J Physiol. 2019 Jan;597(2):499-519. doi: 10.1113/JP276796. Epub 2018 Oct 17. PubMed |
| Osmolarity and calcium regulate connective tissue growth factor (CTGF/CCN2) expression in nucleus pulposus cells. Lin W, Shi C, Wang W, Wu H, Yang C, Wang A, Shen X, Tian Y, Cao P, Yuan W. Gene. 2019 Jul 1;704:15-24. doi: 10.1016/j.gene.2019.04.020. Epub 2019 Apr 6. PubMed |
| Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D. Findlay AR, Bengoechea R, Pittman SK, Chou TF, True HL, Weihl CC. Neurol Genet. 2019 Apr 18;5(2):e318. doi: 10.1212/NXG.0000000000000318. eCollection 2019 Apr. PubMed |
| Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes. Rodriguez-Fdez S, Fernandez-Nevado L, Lorenzo-Martin LF, Bustelo XR. Cells. 2020 Mar 4;9(3). pii: cells9030609. doi: 10.3390/cells9030609. PubMed |
| Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y. Elife. 2020 Mar 18;9. pii: 52779. doi: 10.7554/eLife.52779. PubMed |
| CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response. Niemann B, Li L, Siegler D, Siegler BH, Knapp F, Hanna J, Aslam M, Kracht M, Schulz R, Rohrbach S. Cells. 2020 May 15;9(5). pii: cells9051229. doi: 10.3390/cells9051229. PubMed |
| Anti-cancer potential of persimmon (Diospyros kaki) leaves via the PDGFR-Rac-JNK pathway. Kim HS, Suh JS, Jang YK, Ahn SH, Raja G, Kim JC, Jung Y, Jung SH, Kim TJ. Sci Rep. 2020 Oct 22;10(1):18119. doi: 10.1038/s41598-020-75140-3. PubMed |
| Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes. Chow HM, Sun JK, Hart RP, Cheng KK, Hung CHL, Lau TM, Kwan KM. Adv Sci (Weinh). 2021 Aug;8(16):e2004993. doi: 10.1002/advs.202004993. Epub 2021 Jun 27. PubMed |
| Ligand-Independent G Protein-Coupled Estrogen Receptor/G Protein-Coupled Receptor 30 Activity: Lack of Receptor-Dependent Effects of G-1 and 17beta-Estradiol. Tutzauer J, Gonzalez de Valdivia E, Sward K, Alexandrakis Eilard I, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF. Mol Pharmacol. 2021 Sep;100(3):271-282. doi: 10.1124/molpharm.121.000259. Epub 2021 Jul 30. PubMed |
| Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Yamagishi M, Kubokawa M, Kuze Y, Suzuki A, Yokomizo A, Kobayashi S, Nakashima M, Makiyama J, Iwanaga M, Fukuda T, Watanabe T, Suzuki Y, Uchimaru K. Nat Commun. 2021 Aug 10;12(1):4821. doi: 10.1038/s41467-021-25101-9. PubMed |
| Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. Robles-Valero J, Fernandez-Nevado L, Lorenzo-Martin LF, Cuadrado M, Fernandez-Pisonero I, Rodriguez-Fdez S, Astorga-Simon EN, Abad A, Caloto R, Bustelo XR. EMBO J. 2021 Nov 15;40(22):e108125. doi: 10.15252/embj.2021108125. Epub 2021 Oct 7. PubMed |
| ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis. Ramirez NP, Lee J, Zheng Y, Li L, Dennis B, Chen D, Challa A, Planelles V, Westover KD, Alto NM, D'Orso I. Nat Commun. 2022 Mar 1;13(1):1109. doi: 10.1038/s41467-022-28772-0. PubMed |
| Calcineurin/NFATc2 and PI3K/AKT signaling maintains beta-cell identity and function during metabolic and inflammatory stress. Darden CM, Vasu S, Mattke J, Liu Y, Rhodes CJ, Naziruddin B, Lawrence MC. iScience. 2022 Mar 19;25(4):104125. doi: 10.1016/j.isci.2022.104125. eCollection 2022 Apr 15. PubMed |
| Antibody-dependent cellular cytotoxicity-null effector developed using mammalian and plant GlycoDelete platform. Kang CE, Lee S, Ahn T, Seo DH, Ko BJ, Jung M, Lee J, Kim JY, Kim WT. Sci Rep. 2022 Nov 8;12(1):19030. doi: 10.1038/s41598-022-23311-9. PubMed |
| Long noncoding RNA Malat1 inhibits Tead3-Nfatc1-mediated osteoclastogenesis to suppress osteoporosis and bone metastasis. Zhao Y, Teng H, Deng Y, Sheldon M, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L. Res Sq. 2023 Mar 20:rs.3.rs-2405644. doi: 10.21203/rs.3.rs-2405644/v1. Preprint. PubMed |
| Repurposing pentamidine for cancer immunotherapy by targeting the PD1/PD-L1 immune checkpoint. Gu T, Tian X, Wang Y, Yang W, Li W, Song M, Zhao R, Wang M, Gao Q, Li T, Zhang C, Kundu JK, Liu K, Dong Z, Lee MH. Front Immunol. 2023 May 2;14:1145028. doi: 10.3389/fimmu.2023.1145028. eCollection 2023. PubMed |
| Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis. Zhao Y, Ning J, Teng H, Deng Y, Sheldon M, Shi L, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L. Nat Commun. 2024 Mar 16;15(1):2384. doi: 10.1038/s41467-024-46602-3. PubMed |
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