HA-FOXO3a WT Citations (22)
Originally described in: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME Cell 1999 Mar 19;96(6):857-68. PubMed Journal
Articles Citing HA-FOXO3a WT
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| Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription. Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC. J Biol Chem. 2007 Sep 14;282(37):27298-305. Epub 2007 Jul 10. PubMed |
| Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells. Chen YR, Liu MT, Chang YT, Wu CC, Hu CY, Chen JY. J Virol. 2008 Aug;82(16):8124-37. doi: 10.1128/JVI.00430-08. Epub 2008 Jun 4. PubMed |
| Role of Akt isoforms in IGF-I-mediated signaling and survival in myoblasts. Matheny RW Jr, Adamo ML. Biochem Biophys Res Commun. 2009 Nov 6;389(1):117-21. doi: 10.1016/j.bbrc.2009.08.101. Epub 2009 Aug 22. PubMed |
| Akt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells. Morelli C, Lanzino M, Garofalo C, Maris P, Brunelli E, Casaburi I, Catalano S, Bruno R, Sisci D, Ando S. Mol Cell Biol. 2010 Feb;30(3):857-70. doi: 10.1128/MCB.00824-09. Epub 2009 Nov 23. PubMed |
| FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice. Ambrogini E, Almeida M, Martin-Millan M, Paik JH, Depinho RA, Han L, Goellner J, Weinstein RS, Jilka RL, O'Brien CA, Manolagas SC. Cell Metab. 2010 Feb 3;11(2):136-46. doi: 10.1016/j.cmet.2009.12.009. PubMed |
| Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct. Eckers A, Sauerbier E, Anwar-Mohamed A, Hamann I, Esser C, Schroeder P, El-Kadi AO, Klotz LO. Arch Biochem Biophys. 2011 Dec 15;516(2):138-45. doi: 10.1016/j.abb.2011.10.006. Epub 2011 Oct 15. PubMed |
| FoxO3a is an antimelanogenic factor that mediates antioxidant-induced depigmentation. Kim J, Choi H, Cho EG, Lee TR. J Invest Dermatol. 2014 May;134(5):1378-88. doi: 10.1038/jid.2013.510. Epub 2013 Nov 27. PubMed |
| Sirtuin1 (Sirt1) promotes cortical bone formation by preventing beta-catenin sequestration by FoxO transcription factors in osteoblast progenitors. Iyer S, Han L, Bartell SM, Kim HN, Gubrij I, de Cabo R, O'Brien CA, Manolagas SC, Almeida M. J Biol Chem. 2014 Aug 29;289(35):24069-78. doi: 10.1074/jbc.M114.561803. Epub 2014 Jul 7. PubMed |
| Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kummel D, Goransson U, Becker CW, Gruber CW. Front Chem. 2017 Oct 11;5:73. doi: 10.3389/fchem.2017.00073. eCollection 2017. PubMed |
| Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Celestini V, Tezil T, Russo L, Fasano C, Sanese P, Forte G, Peserico A, Lepore Signorile M, Longo G, De Rasmo D, Signorile A, Gadaleta RM, Scialpi N, Terao M, Garattini E, Cocco T, Villani G, Moschetta A, Grossi V, Simone C. Cell Death Dis. 2018 Feb 14;9(2):231. doi: 10.1038/s41419-018-0336-0. PubMed |
| Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover. Fitzwalter BE, Towers CG, Sullivan KD, Andrysik Z, Hoh M, Ludwig M, O'Prey J, Ryan KM, Espinosa JM, Morgan MJ, Thorburn A. Dev Cell. 2018 Mar 12;44(5):555-565.e3. doi: 10.1016/j.devcel.2018.02.014. PubMed |
| Regulation of miR-34b/c-targeted gene expression program by SUMOylation. Li YJ, Du L, Aldana-Masangkay G, Wang X, Urak R, Forman SJ, Rosen ST, Chen Y. Nucleic Acids Res. 2018 Aug 21;46(14):7108-7123. doi: 10.1093/nar/gky484. PubMed |
| Transcriptional Activity of FOXO Transcription Factors Measured by Luciferase Assays. Avila-Flores A, Arranz-Nicolas J, Merida I. Methods Mol Biol. 2019;1890:91-102. doi: 10.1007/978-1-4939-8900-3_8. PubMed |
| Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells. Osei-Sarfo K, Gudas LJ. PLoS One. 2019 Apr 12;14(4):e0215234. doi: 10.1371/journal.pone.0215234. eCollection 2019. PubMed |
| Transcriptional activation of SIRT6 via FKHRL1/FOXO3a inhibits the Warburg effect in glioblastoma cells. Dong Z, Zhong X, Lei Q, Chen F, Cui H. Cell Signal. 2019 Aug;60:100-113. doi: 10.1016/j.cellsig.2019.04.009. Epub 2019 Apr 17. PubMed |
| The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis. Abdalla MOA, Yamamoto T, Maehara K, Nogami J, Ohkawa Y, Miura H, Poonperm R, Hiratani I, Nakayama H, Nakao M, Saitoh N. Nat Commun. 2019 Aug 22;10(1):3778. doi: 10.1038/s41467-019-11378-4. PubMed |
| Promyelocytic Leukemia (PML) gene regulation: implication towards curbing oncogenesis. Datta N, Islam S, Chatterjee U, Chatterjee S, Panda CK, Ghosh MK. Cell Death Dis. 2019 Sep 10;10(9):656. doi: 10.1038/s41419-019-1889-2. PubMed |
| FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c. Wang L, Zhu X, Sun X, Yang X, Chang X, Xia M, Lu Y, Xia P, Yan H, Bian H, Gao X. Lipids Health Dis. 2019 Nov 15;18(1):197. doi: 10.1186/s12944-019-1132-2. PubMed |
| FOXO3aSIRT6 axis suppresses aerobic glycolysis in melanoma. Dong Z, Yang J, Li L, Tan L, Shi P, Zhang J, Zhong X, Ge L, Wu Z, Cui H. Int J Oncol. 2020 Mar;56(3):728-742. doi: 10.3892/ijo.2020.4964. Epub 2020 Jan 17. PubMed |
| In vitro study of the role of FOXO transcription factors in regulating cigarette smoke extract-induced autophagy. Bagam P, Kaur G, Singh DP, Batra S. Cell Biol Toxicol. 2021 Aug;37(4):531-553. doi: 10.1007/s10565-020-09556-y. Epub 2020 Nov 2. PubMed |
| FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation. Czerny CC, Borschel A, Cai M, Otto M, Hoyer-Fender S. Sci Rep. 2022 Dec 12;12(1):21468. doi: 10.1038/s41598-022-25966-w. PubMed |
| Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Acharya BR, Fang JS, Jeffery ED, Chavkin NW, Genet G, Vasavada H, Nelson EA, Sheynkman GM, Humphries MJ, Hirschi KK. Life Sci Alliance. 2023 May 17;6(8):e202201685. doi: 10.26508/lsa.202201685. Print 2023 Aug. PubMed |
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