pEGFP-C3-hYAP1 Citations (27)
Originally described in: Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis.Basu S, Totty NF, Irwin MS, Sudol M, Downward J Mol Cell. 2003 Jan . 11(1):11-23. PubMed Journal
Articles Citing pEGFP-C3-hYAP1
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Designing Visible Light-Cured Thiol-Acrylate Hydrogels for Studying the HIPPO Pathway Activation in Hepatocellular Carcinoma Cells. Lin TY, Bragg JC, Lin CC. Macromol Biosci. 2015 Dec 28. doi: 10.1002/mabi.201500361. PubMed |
IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. Sayedyahossein S, Li Z, Hedman AC, Morgan CJ, Sacks DB. J Biol Chem. 2016 Sep 9;291(37):19261-73. doi: 10.1074/jbc.M116.732529. Epub 2016 Jul 20. PubMed |
Multiparametric Analysis of Cell Shape Demonstrates that beta-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion. Sero JE, Bakal C. Cell Syst. 2017 Jan 25;4(1):84-96.e6. doi: 10.1016/j.cels.2016.11.015. Epub 2017 Jan 5. PubMed |
Optogenetic control of cellular forces and mechanotransduction.
Valon L, Marin-Llaurado A, Wyatt T, Charras G, Trepat X.
Nat Commun. 2017 Feb 10;8:14396. doi: 10.1038/ncomms14396.
PubMed
Associated Plasmids |
Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival. Robertson A, Mohamed TM, El Maadawi Z, Stafford N, Bui T, Lim DS, Cartwright EJ, Oceandy D. Stem Cell Res. 2017 Apr;20:42-49. doi: 10.1016/j.scr.2017.02.011. Epub 2017 Feb 27. PubMed |
YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed |
Mechano-Signal Transduction in Mesenchymal Stem Cells Induces Prosaposin Secretion to Drive the Proliferation of Breast Cancer Cells. Ishihara S, Inman DR, Li WJ, Ponik SM, Keely PJ. Cancer Res. 2017 Nov 15;77(22):6179-6189. doi: 10.1158/0008-5472.CAN-17-0569. Epub 2017 Sep 28. PubMed |
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Cell. 2017 Nov 30;171(6):1397-1410.e14. doi: 10.1016/j.cell.2017.10.008. Epub 2017 Oct 26. PubMed |
Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing. Gegenfurtner FA, Jahn B, Wagner H, Ziegenhain C, Enard W, Geistlinger L, Radler JO, Vollmar AM, Zahler S. J Cell Sci. 2018 May 29;131(10). pii: jcs.212886. doi: 10.1242/jcs.212886. PubMed |
Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone. Gegenfurtner FA, Zisis T, Al Danaf N, Schrimpf W, Kliesmete Z, Ziegenhain C, Enard W, Kazmaier U, Lamb DC, Vollmar AM, Zahler S. Cell Mol Life Sci. 2018 Dec;75(24):4539-4555. doi: 10.1007/s00018-018-2919-4. Epub 2018 Sep 11. PubMed |
Antiproliferative and Antimigratory Effects of a Novel YAP-TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking. Smith SA, Sessions RB, Shoemark DK, Williams C, Ebrahimighaei R, McNeill MC, Crump MP, McKay TR, Harris G, Newby AC, Bond M. J Med Chem. 2019 Feb 14;62(3):1291-1305. doi: 10.1021/acs.jmedchem.8b01402. Epub 2019 Jan 31. PubMed |
Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins. Hennigan RF, Fletcher JS, Guard S, Ratner N. Sci Signal. 2019 Apr 23;12(578):eaau8749. doi: 10.1126/scisignal.aau8749. PubMed |
Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. Rojek KO, Krzemien J, Dolezyczek H, Boguszewski PM, Kaczmarek L, Konopka W, Rylski M, Jaworski J, Holmgren L, Proszynski TJ. PLoS Biol. 2019 May 1;17(5):e3000253. doi: 10.1371/journal.pbio.3000253. eCollection 2019 May. PubMed |
Sustained Oscillations of Epithelial Cell Sheets. Peyret G, Mueller R, d'Alessandro J, Begnaud S, Marcq P, Mege RM, Yeomans JM, Doostmohammadi A, Ladoux B. Biophys J. 2019 Aug 6;117(3):464-478. doi: 10.1016/j.bpj.2019.06.013. Epub 2019 Jul 2. PubMed |
Pharmacological inhibition of Hippo pathway, with the novel kinase inhibitor XMU-MP-1, protects the heart against adverse effects during pressure overload. Triastuti E, Nugroho AB, Zi M, Prehar S, Kohar YS, Bui TA, Stafford N, Cartwright EJ, Abraham S, Oceandy D. Br J Pharmacol. 2019 Oct;176(20):3956-3971. doi: 10.1111/bph.14795. Epub 2019 Oct 8. PubMed |
YAP promotes the proliferation of neuroblastoma cells through decreasing the nuclear location of p27(Kip1) mediated by Akt. Shen X, Xu X, Xie C, Liu H, Yang D, Zhang J, Wu Q, Feng W, Wang L, Du L, Xuan L, Meng C, Zhang H, Wang W, Wang Y, Xie T, Huang Z. Cell Prolif. 2019 Dec 20:e12734. doi: 10.1111/cpr.12734. PubMed |
AMOTL1 enhances YAP1 stability and promotes YAP1-driven gastric oncogenesis. Zhou Y, Zhang J, Li H, Huang T, Wong CC, Wu F, Wu M, Weng N, Liu L, Cheng ASL, Yu J, Wong N, Lo KW, Tang PMK, Kang W, To KF. Oncogene. 2020 May;39(22):4375-4389. doi: 10.1038/s41388-020-1293-5. Epub 2020 Apr 20. PubMed |
Mechanical Stimulation of Adhesion Receptors Using Light-Responsive Nanoparticle Actuators Enhances Myogenesis. Ramey-Ward AN, Su H, Salaita K. ACS Appl Mater Interfaces. 2020 Aug 12;12(32):35903-35917. doi: 10.1021/acsami.0c08871. Epub 2020 Jul 29. PubMed |
D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway. Xu X, Shen X, Feng W, Yang D, Jin L, Wang J, Wang M, Ting Z, Xue F, Zhang J, Meng C, Chen R, Zheng X, Du L, Xuan L, Wang Y, Xie T, Huang Z. Aging (Albany NY). 2020 Sep 29;12(18):18501-18521. doi: 10.18632/aging.103819. PubMed |
alpha-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation. Pavel M, Park SJ, Frake RA, Son SM, Manni MM, Bento CF, Renna M, Ricketts T, Menzies FM, Tanasa R, Rubinsztein DC. Nat Commun. 2021 Mar 17;12(1):1703. doi: 10.1038/s41467-021-21882-1. PubMed |
Oxidative Stress-Mediated YAP Dysregulation Contributes to the Pathogenesis of Pemphigus Vulgaris. Huang Y, Jedlickova H, Cai Y, Rehman A, Gammon L, Ahmad US, Uttagomol J, Parkinson EK, Fortune F, Wan H. Front Immunol. 2021 Apr 19;12:649502. doi: 10.3389/fimmu.2021.649502. eCollection 2021. PubMed |
Transcriptional co-activators YAP1-TAZ of Hippo signalling in doxorubicin-induced cardiomyopathy. Berecz T, Yiu A, Vittay O, Orsolits B, Mioulane M, Dos Remedios CG, Ketteler R, Merkely B, Apati A, Harding SE, Hellen N, Foldes G. ESC Heart Fail. 2022 Feb;9(1):224-235. doi: 10.1002/ehf2.13756. Epub 2021 Dec 21. PubMed |
Peptide 17 alleviates early hypertensive renal injury by regulating the Hippo/YAP signalling pathway. Xu SB, Xu B, Ma ZH, Huang MQ, Gao ZS, Ni JL. Nephrology (Carlton). 2022 Aug;27(8):712-723. doi: 10.1111/nep.14066. Epub 2022 Jul 5. PubMed |
Merlin tumor suppressor function is regulated by PIP2-mediated dimerization. Hennigan RF, Thomson CS, Stachowski K, Nassar N, Ratner N. PLoS One. 2023 Feb 21;18(2):e0281876. doi: 10.1371/journal.pone.0281876. eCollection 2023. PubMed |
Chlamydia trachomatis induces the transcriptional activity of host YAP in a Hippo-independent fashion. Caven LT, Brinkworth AJ, Carabeo RA. Front Cell Infect Microbiol. 2023 Feb 27;13:1098420. doi: 10.3389/fcimb.2023.1098420. eCollection 2023. PubMed |
NEK1-Mediated Phosphorylation of YAP1 Is Key to Prostate Cancer Progression. Ghosh I, Khalil MI, Mirza R, King J, Olatunde D, De Benedetti A. Biomedicines. 2023 Feb 28;11(3):734. doi: 10.3390/biomedicines11030734. PubMed |
Nuclear compression regulates YAP spatiotemporal fluctuations in living cells. Koushki N, Ghagre A, Srivastava LK, Molter C, Ehrlicher AJ. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2301285120. doi: 10.1073/pnas.2301285120. Epub 2023 Jul 3. PubMed |
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