p2xFLAGhYAP1-S127A Citations (14)

Originally described in: WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus.
Komuro A, Nagai M, Navin NE, Sudol M J Biol Chem. 2003 Aug 29. 278(35):33334-41. PubMed Journal

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Articles Citing p2xFLAGhYAP1-S127A

Articles
The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells. Judson RN, Tremblay AM, Knopp P, White RB, Urcia R, De Bari C, Zammit PS, Camargo FD, Wackerhage H. J Cell Sci. 2012 Dec 15;125(Pt 24):6009-19. doi: 10.1242/jcs.109546. Epub 2012 Oct 4. PubMed
Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells. Karystinou A, Roelofs AJ, Neve A, Cantatore FP, Wackerhage H, De Bari C. Arthritis Res Ther. 2015 May 30;17:147. doi: 10.1186/s13075-015-0639-9. PubMed
NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition. Garcia-Rendueles ME, Ricarte-Filho JC, Untch BR, Landa I, Knauf JA, Voza F, Smith VE, Ganly I, Taylor BS, Persaud Y, Oler G, Fang Y, Jhanwar SC, Viale A, Heguy A, Huberman KH, Giancotti F, Ghossein R, Fagin JA. Cancer Discov. 2015 Nov;5(11):1178-93. doi: 10.1158/2159-8290.CD-15-0330. Epub 2015 Sep 10. PubMed
Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. Kemppainen K, Wentus N, Lassila T, Laiho A, Tornquist K. Cell Signal. 2016 Dec;28(12):1894-1903. doi: 10.1016/j.cellsig.2016.09.004. Epub 2016 Sep 12. PubMed
YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function. Sun C, De Mello V, Mohamed A, Ortuste Quiroga HP, Garcia-Munoz A, Al Bloshi A, Tremblay AM, von Kriegsheim A, Collie-Duguid E, Vargesson N, Matallanas D, Wackerhage H, Zammit PS. Stem Cells. 2017 Aug;35(8):1958-1972. doi: 10.1002/stem.2652. Epub 2017 Jun 27. PubMed
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Cell. 2017 Nov 30;171(6):1397-1410.e14. doi: 10.1016/j.cell.2017.10.008. Epub 2017 Oct 26. PubMed
Substrate mechanics controls adipogenesis through YAP phosphorylation by dictating cell spreading. Oliver-De La Cruz J, Nardone G, Vrbsky J, Pompeiano A, Perestrelo AR, Capradossi F, Melajova K, Filipensky P, Forte G. Biomaterials. 2019 Jun;205:64-80. doi: 10.1016/j.biomaterials.2019.03.009. Epub 2019 Mar 16. PubMed
A RASSF1A-HIF1alpha loop drives Warburg effect in cancer and pulmonary hypertension. Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza GL, Meister M, Muley T, Seeger-Nukpezah T, Samakovlis C, Weissmann N, Grimminger F, Seeger W, Savai R, Pullamsetti SS. Nat Commun. 2019 May 13;10(1):2130. doi: 10.1038/s41467-019-10044-z. PubMed
Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1. Zhang X, Liu P, Shang Y, Kerndl H, Kumstel S, Gong P, Vollmar B, Zechner D. J Cancer. 2020 Jan 1;11(2):479-487. doi: 10.7150/jca.33029. eCollection 2020. PubMed
RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERalpha)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2. Rosswag S, Sleeman JP, Thaler S. Cells. 2021 Oct 24;10(11). pii: cells10112868. doi: 10.3390/cells10112868. PubMed
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma. Li Y, Yang J, Zhang Q, Xu S, Sun W, Ge S, Xu X, Jager MJ, Jia R, Zhang J, Fan X. Oncogene. 2022 Jul;41(27):3539-3553. doi: 10.1038/s41388-022-02364-0. Epub 2022 Jun 13. PubMed
A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma. Lin WH, Feathers RW, Cooper LM, Lewis-Tuffin LJ, Chen J, Sarkaria JN, Anastasiadis PZ. JCI Insight. 2023 Jul 10;8(13):e157491. doi: 10.1172/jci.insight.157491. PubMed
Competence for neural crest induction is controlled by hydrostatic pressure through Yap. Alasaadi DN, Alvizi L, Hartmann J, Stillman N, Moghe P, Hiiragi T, Mayor R. Nat Cell Biol. 2024 Apr;26(4):530-541. doi: 10.1038/s41556-024-01378-y. Epub 2024 Mar 18. PubMed

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