pBABE-puro-DN-hTERT Citations (7)

Originally described in: Inhibition of telomerase limits the growth of human cancer cells.
Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA Nat Med 1999 Oct;5(10):1164-70. PubMed Journal

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Articles Citing pBABE-puro-DN-hTERT

Articles
Acycloguanosyl 5'-thymidyltriphosphate, a thymidine analogue prodrug activated by telomerase, reduces pancreatic tumor growth in mice. Polvani S, Calamante M, Foresta V, Ceni E, Mordini A, Quattrone A, D'Amico M, Luchinat C, Bertini I, Galli A. Gastroenterology. 2011 Feb;140(2):709-720.e9. doi: 10.1053/j.gastro.2010.10.050. Epub 2010 Oct 30. PubMed
Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma. Ahmad F, Dixit D, Sharma V, Kumar A, Joshi SD, Sarkar C, Sen E. Cell Death Dis. 2016 May 5;7:e2213. doi: 10.1038/cddis.2016.117. PubMed
Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence. Patel PL, Suram A, Mirani N, Bischof O, Herbig U. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5024-33. doi: 10.1073/pnas.1602379113. Epub 2016 Aug 8. PubMed
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors. Mahfouz N, Tahtouh R, Alaaeddine N, El Hajj J, Sarkis R, Hachem R, Raad I, Hilal G. PLoS One. 2017 Jun 8;12(6):e0179202. doi: 10.1371/journal.pone.0179202. eCollection 2017. PubMed
Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells. Zhang Z, Yu L, Dai G, Xia K, Liu G, Song Q, Tao C, Gao T, Guo W. Sci Rep. 2017 Aug 1;7(1):7070. doi: 10.1038/s41598-017-07204-w. PubMed
Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma. Ahmad F, Patrick S, Sheikh T, Sharma V, Pathak P, Malgulwar PB, Kumar A, Joshi SD, Sarkar C, Sen E. J Neurochem. 2017 Dec;143(6):671-683. doi: 10.1111/jnc.14152. Epub 2017 Sep 22. PubMed
Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness. Bernabe-Garcia M, Martinez-Balsalobre E, Garcia-Moreno D, Garcia-Castillo J, Revilla-Nuin B, Blanco-Alcaina E, Mulero V, Alcaraz-Perez F, Cayuela ML. Mol Oncol. 2021 Jul;15(7):1818-1834. doi: 10.1002/1878-0261.12943. Epub 2021 May 2. PubMed

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