pBabe-puro Ras V12 Citations (31)
Originally described in: pBABE-vectorsUnpublished
Articles Citing pBabe-puro Ras V12
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| Genetic dissection of histone deacetylase requirement in tumor cells. Haberland M, Johnson A, Mokalled MH, Montgomery RL, Olson EN. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7751-5. doi: 10.1073/pnas.0903139106. Epub 2009 Apr 29. PubMed |
| 2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells. DeAngelis JT, Li Y, Mitchell N, Wilson L, Kim H, Tollefsbol TO. J Proteome Res. 2011 Feb 4;10(2):447-58. doi: 10.1021/pr100533k. Epub 2010 Dec 20. PubMed |
| Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C. Cell Stem Cell. 2011 Feb 4;8(2):149-63. doi: 10.1016/j.stem.2010.12.007. PubMed |
| c-MYC functions as a molecular switch to alter the response of human mammary epithelial cells to oncostatin M. Kan CE, Cipriano R, Jackson MW. Cancer Res. 2011 Nov 15;71(22):6930-9. doi: 10.1158/0008-5472.CAN-10-3860. Epub 2011 Oct 5. PubMed |
| Activation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD). Campbell HG, Mehta R, Neumann AA, Rubio C, Baird M, Slatter TL, Braithwaite AW. Oncogene. 2013 Feb 14;32(7):827-36. doi: 10.1038/onc.2012.102. Epub 2012 Apr 9. PubMed |
| Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U. EMBO J. 2012 Jun 29;31(13):2839-51. doi: 10.1038/emboj.2012.132. Epub 2012 May 8. PubMed |
| Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Ma X, Choudhury SN, Hua X, Dai Z, Li Y. Carcinogenesis. 2013 Jun;34(6):1216-23. doi: 10.1093/carcin/bgt044. Epub 2013 Feb 5. PubMed |
| Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells. Junk DJ, Cipriano R, Stampfer M, Jackson MW. PLoS One. 2013;8(2):e53776. doi: 10.1371/journal.pone.0053776. Epub 2013 Feb 4. PubMed |
| FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Cipriano R, Miskimen KL, Bryson BL, Foy CR, Bartel CA, Jackson MW. Oncotarget. 2013 May;4(5):729-38. PubMed |
| Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15. Inoue S, Hao Z, Elia AJ, Cescon D, Zhou L, Silvester J, Snow B, Harris IS, Sasaki M, Li WY, Itsumi M, Yamamoto K, Ueda T, Dominguez-Brauer C, Gorrini C, Chio II, Haight J, You-Ten A, McCracken S, Wakeham A, Ghazarian D, Penn LJ, Melino G, Mak TW. Genes Dev. 2013 May 15;27(10):1101-14. doi: 10.1101/gad.214577.113. PubMed |
| AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation. Jackstadt R, Jung P, Hermeking H. Cell Death Dis. 2013 Aug 15;4:e775. doi: 10.1038/cddis.2013.282. PubMed |
| Subcellular localization-dependent changes in EGFP fluorescence lifetime measured by time-resolved flow cytometry. Gohar AV, Cao R, Jenkins P, Li W, Houston JP, Houston KD. Biomed Opt Express. 2013 Jul 19;4(8):1390-400. doi: 10.1364/BOE.4.001390. eCollection 2013. PubMed |
| The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage response. Cao X, Kong CM, Mathi KM, Lim YP, Cacheux-Rataboul V, Wang X. BMC Biochem. 2014 Aug 7;15:17. doi: 10.1186/1471-2091-15-17. PubMed |
| The role of miR-200a in mammalian epithelial cell transformation. Becker LE, Takwi AA, Lu Z, Li Y. Carcinogenesis. 2015 Jan;36(1):2-12. doi: 10.1093/carcin/bgu202. Epub 2014 Sep 19. PubMed |
Actin stress in cell reprogramming.
Guo J, Wang Y, Sachs F, Meng F.
Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5252-61. doi: 10.1073/pnas.1411683111. Epub 2014 Nov 24.
PubMed
Associated Plasmids |
| Rho kinase inhibitors block melanoma cell migration and inhibit metastasis. Sadok A, McCarthy A, Caldwell J, Collins I, Garrett MD, Yeo M, Hooper S, Sahai E, Kuemper S, Mardakheh FK, Marshall CJ. Cancer Res. 2015 Jun 1;75(11):2272-84. doi: 10.1158/0008-5472.CAN-14-2156. Epub 2015 Apr 3. PubMed |
| KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Leiser D, Medova M, Mikami K, Nisa L, Stroka D, Blaukat A, Bladt F, Aebersold DM, Zimmer Y. Mol Oncol. 2015 Apr 14. pii: S1574-7891(15)00089-7. doi: 10.1016/j.molonc.2015.04.001. PubMed |
| AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts. Pelletier J, Roux D, Viollet B, Mazure NM, Pouyssegur J. Oncotarget. 2015 May 20;6(14):11833-47. PubMed |
| Design and Characterization of Bioengineered Cancer-Like Stem Cells. Cho S, Park H, Jarboe EA, Peterson CM, Bae YH, Janat-Amsbury MM. PLoS One. 2015 Oct 21;10(10):e0141172. doi: 10.1371/journal.pone.0141172. eCollection 2015. PubMed |
| Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. Kumper S, Mardakheh FK, McCarthy A, Yeo M, Stamp GW, Paul A, Worboys J, Sadok A, Jorgensen C, Guichard S, Marshall CJ. Elife. 2016 Jan 14;5. pii: e12203. doi: 10.7554/eLife.12203. PubMed |
| Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence. Patel PL, Suram A, Mirani N, Bischof O, Herbig U. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5024-33. doi: 10.1073/pnas.1602379113. Epub 2016 Aug 8. PubMed |
| Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma. Dang H, Takai A, Forgues M, Pomyen Y, Mou H, Xue W, Ray D, Ha KCH, Morris QD, Hughes TR, Wang XW. Cancer Cell. 2017 Jul 10;32(1):101-114.e8. doi: 10.1016/j.ccell.2017.06.002. PubMed |
| MELK expression correlates with tumor mitotic activity but is not required for cancer growth. Giuliano CJ, Lin A, Smith JC, Palladino AC, Sheltzer JM. Elife. 2018 Feb 8;7. pii: 32838. doi: 10.7554/eLife.32838. PubMed |
| MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state. Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A. Nat Commun. 2018 Mar 9;9(1):1024. doi: 10.1038/s41467-018-03264-2. PubMed |
| Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer. Yang Z, Shah K, Busby T, Giles K, Khodadadi-Jamayran A, Li W, Jiang H. J Clin Invest. 2018 Aug 1;128(8):3605-3618. doi: 10.1172/JCI97072. Epub 2018 Jul 23. PubMed |
| A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence. Kim YY, Um JH, Yun J. J Vis Exp. 2018 Aug 12;(138). doi: 10.3791/57890. PubMed |
| Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts. Razdan N, Vasilopoulos T, Herbig U. Aging Cell. 2018 Dec;17(6):e12838. doi: 10.1111/acel.12838. Epub 2018 Sep 22. PubMed |
| Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts. Mangialardi EM, Chen K, Salmon B, Vacher J, Salmena L. Oncotarget. 2019 Oct 29;10(59):6378-6390. doi: 10.18632/oncotarget.27293. eCollection 2019 Oct 29. PubMed |
| Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase. Reisman BJ, Guo H, Ramsey HE, Wright MT, Reinfeld BI, Ferrell PB, Sulikowski GA, Rathmell WK, Savona MR, Plate L, Rubinstein JL, Bachmann BO. Nat Chem Biol. 2022 Apr;18(4):360-367. doi: 10.1038/s41589-021-00900-9. Epub 2021 Dec 2. PubMed |
| Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars. Martinez-Zamudio RI, Stefa A, Nabuco Leva Ferreira Freitas JA, Vasilopoulos T, Simpson M, Dore G, Roux PF, Galan MA, Chokshi RJ, Bischof O, Herbig U. Cell Genom. 2023 Apr 5;3(4):100293. doi: 10.1016/j.xgen.2023.100293. eCollection 2023 Apr 12. PubMed |
| Oncogenic Transformation Drives DNA Methylation Loss and Transcriptional Activation at Transposable Element Loci. Kanholm T, Rentia U, Hadley M, Karlow JA, Cox OL, Diab N, Bendall ML, Dawson T, McDonald JI, Xie W, Crandall KA, Burns KH, Baylin SB, Easwaran H, Chiappinelli KB. Cancer Res. 2023 Aug 1;83(15):2584-2599. doi: 10.1158/0008-5472.CAN-22-3485. PubMed |
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