pBABE-puro Citations (229)
Originally described in: Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.Morgenstern JP, Land H Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. PubMed
Articles Citing pBABE-puro
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| Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Kleeff J, Maruyama H, Friess H, Buchler MW, Falb D, Korc M. Biochem Biophys Res Commun. 1999 Feb 16;255(2):268-73. PubMed |
| Human pancreatic duct epithelial cell model for KRAS transformation. Radulovich N, Qian JY, Tsao MS. Methods Enzymol. 2008;439:1-13. doi: 10.1016/S0076-6879(07)00401-6. PubMed |
| Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures. Abu-Yousif AO, Smith KA, Getsios S, Green KJ, Van Dross RT, Pelling JC. Cancer Res. 2008 Apr 15;68(8):3057-65. doi: 10.1158/0008-5472.CAN-07-2763. PubMed |
| Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells. Chapman EJ, Kelly G, Knowles MA. Mol Cancer Res. 2008 Jul;6(7):1154-68. doi: 10.1158/1541-7786.MCR-07-2168. PubMed |
| Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha. Han S, Ritzenthaler JD, Sun X, Zheng Y, Roman J. Am J Respir Cell Mol Biol. 2009 Mar;40(3):325-31. doi: 10.1165/rcmb.2008-0197OC. Epub 2008 Sep 5. PubMed |
| Systematic identification of cis-silenced genes by trans complementation. Lee JH, Bugarija B, Millan EJ, Walton NM, Gaetz J, Fernandes CJ, Yu WH, Mekel-Bobrov N, Vallender TW, Snyder GE, Xiang AP, Lahn BT. Hum Mol Genet. 2009 Mar 1;18(5):835-46. doi: 10.1093/hmg/ddn409. Epub 2008 Dec 2. PubMed |
| NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells. Singh S, Zahid M, Saeed M, Gaikwad NW, Meza JL, Cavalieri EL, Rogan EG, Chakravarti D. J Steroid Biochem Mol Biol. 2009 Oct;117(1-3):56-66. doi: 10.1016/j.jsbmb.2009.07.003. Epub 2009 Jul 21. PubMed |
Ageing-related chromatin defects through loss of the NURD complex.
Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T.
Nat Cell Biol. 2009 Oct . 11(10):1261-7.
PubMed
Associated Plasmids |
| Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling. Guo J, Cagatay T, Zhou G, Chan CC, Blythe S, Suyama K, Zheng L, Pan K, Qian C, Hamelin R, Thibodeau SN, Klein PS, Wharton KA, Liu W. PLoS One. 2009 . 4(11):e7982. PubMed |
| Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. Ghosh S, Koblinski J, Johnson J, Liu Y, Ericsson A, Davis JW, Shi Z, Ravosa MJ, Crawford S, Frazier S, Stack MS. Mol Cancer Res. 2010 Feb;8(2):145-58. doi: 10.1158/1541-7786.MCR-09-0045. Epub 2010 Feb 9. PubMed |
| PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling. Halilovic E, She QB, Ye Q, Pagliarini R, Sellers WR, Solit DB, Rosen N. Cancer Res. 2010 Sep 1;70(17):6804-14. doi: 10.1158/0008-5472.CAN-10-0409. Epub 2010 Aug 10. PubMed |
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.
Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, Garber M, Curran M, Onder T, Agarwal S, Manos PD, Datta S, Lander ES, Schlaeger TM, Daley GQ, Rinn JL.
Nat Genet. 2010 Dec;42(12):1113-7. Epub 2010 Nov 7.
PubMed
Associated Plasmids |
| Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway. Jagani Z, Mora-Blanco EL, Sansam CG, McKenna ES, Wilson B, Chen D, Klekota J, Tamayo P, Nguyen PT, Tolstorukov M, Park PJ, Cho YJ, Hsiao K, Buonamici S, Pomeroy SL, Mesirov JP, Ruffner H, Bouwmeester T, Luchansky SJ, Murtie J, Kelleher JF, Warmuth M, Sellers WR, Roberts CW, Dorsch M. Nat Med. 2010 Dec;16(12):1429-33. doi: 10.1038/nm.2251. Epub 2010 Nov 14. PubMed |
| Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. Tamama K, Kawasaki H, Kerpedjieva SS, Guan J, Ganju RK, Sen CK. J Cell Biochem. 2011 Mar;112(3):804-17. doi: 10.1002/jcb.22961. PubMed |
| Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1beta via late phase activation of nuclear factor kappaB and expression of phagocyte-type NADPH oxidase. Yoshimura K, Miyamoto Y, Yasuhara R, Maruyama T, Akiyama T, Yamada A, Takami M, Suzawa T, Tsunawaki S, Tachikawa T, Baba K, Kamijo R. J Biol Chem. 2011 Apr 29;286(17):14744-52. doi: 10.1074/jbc.M111.221259. Epub 2011 Mar 3. PubMed |
| Large scale RNAi screen reveals that the inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation. Wu N, Castel D, Debily MA, Vigano MA, Alibert O, Mantovani R, Iljin K, Romeo PH, Gidrol X. J Biol Chem. 2011 Jun 10;286(23):20870-9. doi: 10.1074/jbc.M110.169433. Epub 2011 Apr 10. PubMed |
| The role of Pea3 group transcription factors in esophageal squamous cell carcinoma. Yuen HF, McCrudden CM, Chan KK, Chan YP, Wong ML, Chan KY, Khoo US, Law S, Srivastava G, Lappin TR, Chan KW, El-Tanani M. Am J Pathol. 2011 Aug;179(2):992-1003. doi: 10.1016/j.ajpath.2011.04.004. Epub 2011 May 31. PubMed |
Immortalization and characterization of osteoblast cell lines generated from wild-type and Nmp4-null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT).
Alvarez MB, Childress P, Philip BK, Gerard-O'Riley R, Hanlon M, Herbert BS, Robling AG, Pavalko FM, Bidwell JP.
J Cell Physiol. 2012 May;227(5):1873-82. doi: 10.1002/jcp.22915.
PubMed
Associated Plasmids |
| Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-beta in endothelial cells. Xie L, Vo-Ransdell C, Abel B, Willoughby C, Jang S, Sowa G. Am J Physiol Cell Physiol. 2011 Nov;301(5):C1161-74. doi: 10.1152/ajpcell.00486.2010. Epub 2011 Aug 10. PubMed |
| The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement. Tai AW, Salloum S. PLoS One. 2011;6(10):e26300. doi: 10.1371/journal.pone.0026300. Epub 2011 Oct 12. PubMed |
| Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak. Wang C, Youle RJ. Oncogene. 2012 Jun 28;31(26):3177-89. doi: 10.1038/onc.2011.497. Epub 2011 Nov 7. PubMed |
| Calpain 2-dependent IkappaBalpha degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts. Fenouille N, Grosso S, Yunchao S, Mary D, Pontier-Bres R, Imbert V, Czerucka D, Caroli-Bosc FX, Peyron JF, Lagadec P. J Pathol. 2012 May;227(1):118-29. doi: 10.1002/path.3034. Epub 2012 Feb 9. PubMed |
| Identification of a link between Wnt/beta-catenin signalling and the cell fusion pathway. Matsuura K, Jigami T, Taniue K, Morishita Y, Adachi S, Senda T, Nonaka A, Aburatani H, Nakamura T, Akiyama T. Nat Commun. 2011 Nov 22;2:548. doi: 10.1038/ncomms1551. PubMed |
| Activation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD). Campbell HG, Mehta R, Neumann AA, Rubio C, Baird M, Slatter TL, Braithwaite AW. Oncogene. 2013 Feb 14;32(7):827-36. doi: 10.1038/onc.2012.102. Epub 2012 Apr 9. PubMed |
| Genome-wide screen for miRNA targets using the MISSION target ID library. Coussens MJ, Forbes K, Kreader C, Sago J, Cupp C, Swarthout J. J Vis Exp. 2012 Apr 6;(62):e3303. doi: 10.3791/3303. PubMed |
| Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms. Law ME, Corsino PE, Jahn SC, Davis BJ, Chen S, Patel B, Pham K, Lu J, Sheppard B, Norgaard P, Hong J, Higgins P, Kim JS, Luesch H, Law BK. Oncogene. 2013 Mar 7;32(10):1316-29. doi: 10.1038/onc.2012.138. Epub 2012 Apr 30. PubMed |
| Role of the tripartite motif protein 27 in cancer development. Zoumpoulidou G, Broceno C, Li H, Bird D, Thomas G, Mittnacht S. J Natl Cancer Inst. 2012 Jun 20;104(12):941-52. doi: 10.1093/jnci/djs224. Epub 2012 May 3. PubMed |
| Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U. EMBO J. 2012 Jun 29;31(13):2839-51. doi: 10.1038/emboj.2012.132. Epub 2012 May 8. PubMed |
| Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion. Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, Hostetter G, Weiss GJ, Kingsley CB, Loftus JC, Bremner R, Tran NL, Winkles JA. Am J Pathol. 2012 Jul;181(1):111-20. doi: 10.1016/j.ajpath.2012.03.026. Epub 2012 May 23. PubMed |
| Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, Vallentin A, Vial H, Vidal M, Szakacs G. PLoS One. 2012;7(5):e37378. doi: 10.1371/journal.pone.0037378. Epub 2012 May 24. PubMed |
| Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Cell. 2012 Jun 22;149(7):1565-77. doi: 10.1016/j.cell.2012.04.039. PubMed |
| The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells. Marina M, Wang L, Conrad SE. Cell Commun Signal. 2012 Jul 9;10(1):18. doi: 10.1186/1478-811X-10-18. PubMed |
| Dissecting the role of human embryonic stem cell-derived mesenchymal cells in human umbilical vein endothelial cell network stabilization in three-dimensional environments. Boyd NL, Nunes SS, Krishnan L, Jokinen JD, Ramakrishnan VM, Bugg AR, Hoying JB. Tissue Eng Part A. 2013 Jan;19(1-2):211-23. doi: 10.1089/ten.tea.2011.0408. Epub 2012 Sep 12. PubMed |
| Role for telomerase in Listeria monocytogenes infection. Samba-Louaka A, Stavru F, Cossart P. Infect Immun. 2012 Dec;80(12):4257-63. doi: 10.1128/IAI.00614-12. Epub 2012 Sep 24. PubMed |
| Defining Akt actions in muscle differentiation. Gardner S, Anguiano M, Rotwein P. Am J Physiol Cell Physiol. 2012 Dec 15;303(12):C1292-300. doi: 10.1152/ajpcell.00259.2012. Epub 2012 Oct 17. PubMed |
| Role of transcriptional corepressor ETO2 in erythroid cells. Fujiwara T, Alqadi YW, Okitsu Y, Fukuhara N, Onishi Y, Ishizawa K, Harigae H. Exp Hematol. 2013 Mar;41(3):303-15.e1. doi: 10.1016/j.exphem.2012.10.015. Epub 2012 Nov 2. PubMed |
Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.
Karimova M, Abi-Ghanem J, Berger N, Surendranath V, Pisabarro MT, Buchholz F.
Nucleic Acids Res. 2013 Jan;41(2):e37. doi: 10.1093/nar/gks1037. Epub 2012 Nov 9.
PubMed
Associated Plasmids |
| ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR. Thomas C, Rajapaksa G, Nikolos F, Hao R, Katchy A, McCollum CW, Bondesson M, Quinlan P, Thompson A, Krishnamurthy S, Esteva FJ, Gustafsson JA. Breast Cancer Res. 2012 Nov 16;14(6):R148. doi: 10.1186/bcr3358. PubMed |
| Monitoring nutrient signaling through the longevity protein p66(SHC(1)). Ranieri SC, Pani G. Methods Mol Biol. 2013;965:341-53. doi: 10.1007/978-1-62703-239-1_23. PubMed |
| LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Shackelford DB, Abt E, Gerken L, Vasquez DS, Seki A, Leblanc M, Wei L, Fishbein MC, Czernin J, Mischel PS, Shaw RJ. Cancer Cell. 2013 Feb 11;23(2):143-58. doi: 10.1016/j.ccr.2012.12.008. Epub 2013 Jan 24. PubMed |
| Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells. Junk DJ, Cipriano R, Stampfer M, Jackson MW. PLoS One. 2013;8(2):e53776. doi: 10.1371/journal.pone.0053776. Epub 2013 Feb 4. PubMed |
| Phosphorylation of the CENP-A amino-terminus in mitotic centromeric chromatin is required for kinetochore function. Goutte-Gattat D, Shuaib M, Ouararhni K, Gautier T, Skoufias DA, Hamiche A, Dimitrov S. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8579-84. doi: 10.1073/pnas.1302955110. Epub 2013 May 8. PubMed |
| Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells. Chen QK, Lee K, Radisky DC, Nelson CM. Differentiation. 2013 Oct;86(3):126-32. doi: 10.1016/j.diff.2013.03.003. Epub 2013 May 6. PubMed |
| Transforming growth factor beta induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Ding ZY, Jin GN, Liang HF, Wang W, Chen WX, Datta PK, Zhang MZ, Zhang B, Chen XP. Cell Signal. 2013 Oct;25(10):1981-92. doi: 10.1016/j.cellsig.2013.05.027. Epub 2013 May 28. PubMed |
| Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing. O'Seaghdha M, Wessels MR. PLoS Pathog. 2013;9(6):e1003394. doi: 10.1371/journal.ppat.1003394. Epub 2013 Jun 6. PubMed |
| CITED2 modulates estrogen receptor transcriptional activity in breast cancer cells. Lau WM, Doucet M, Huang D, Weber KL, Kominsky SL. Biochem Biophys Res Commun. 2013 Jul 26;437(2):261-6. doi: 10.1016/j.bbrc.2013.06.063. Epub 2013 Jun 27. PubMed |
| Enpp1: a potential facilitator of breast cancer bone metastasis. Lau WM, Doucet M, Stadel R, Huang D, Weber KL, Kominsky SL. PLoS One. 2013 Jul 5;8(7):e66752. doi: 10.1371/journal.pone.0066752. Print 2013. PubMed |
| Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy. Fogel AI, Dlouhy BJ, Wang C, Ryu SW, Neutzner A, Hasson SA, Sideris DP, Abeliovich H, Youle RJ. Mol Cell Biol. 2013 Sep;33(18):3675-88. doi: 10.1128/MCB.00079-13. Epub 2013 Jul 22. PubMed |
| A pharmacological model reveals biased dependency on PI3K isoforms for tumor cell growth. Wang X, Li JP, Yang Y, Ding J, Meng LH. Acta Pharmacol Sin. 2013 Sep;34(9):1201-7. doi: 10.1038/aps.2013.81. Epub 2013 Jul 29. PubMed |
| Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules. Guo H, Gao M, Lu Y, Liang J, Lorenzi PL, Bai S, Hawke DH, Li J, Dogruluk T, Scott KL, Jonasch E, Mills GB, Ding Z. Oncogene. 2014 Jun 26;33(26):3463-72. doi: 10.1038/onc.2013.301. Epub 2013 Aug 5. PubMed |
| Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling. Kitade M, Factor VM, Andersen JB, Tomokuni A, Kaji K, Akita H, Holczbauer A, Seo D, Marquardt JU, Conner EA, Lee SB, Lee YH, Thorgeirsson SS. Genes Dev. 2013 Aug 1;27(15):1706-17. doi: 10.1101/gad.214601.113. PubMed |
| AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation. Jackstadt R, Jung P, Hermeking H. Cell Death Dis. 2013 Aug 15;4:e775. doi: 10.1038/cddis.2013.282. PubMed |
| Elucidation of the role of LMO2 in human erythroid cells. Inoue A, Fujiwara T, Okitsu Y, Katsuoka Y, Fukuhara N, Onishi Y, Ishizawa K, Harigae H. Exp Hematol. 2013 Dec;41(12):1062-76.e1. doi: 10.1016/j.exphem.2013.09.003. Epub 2013 Sep 13. PubMed |
| A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease. Fujiwara T, Ikeda T, Nagasaka Y, Okitsu Y, Katsuoka Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Tomosugi N, Harigae H. PLoS One. 2013 Sep 27;8(9):e75568. doi: 10.1371/journal.pone.0075568. eCollection 2013. PubMed |
| DNMT1-interacting RNAs block gene-specific DNA methylation. Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Alo F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG. Nature. 2013 Nov 21;503(7476):371-6. doi: 10.1038/nature12598. Epub 2013 Oct 9. PubMed |
| BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP. Morotti A, Panuzzo C, Crivellaro S, Pergolizzi B, Familiari U, Berger AH, Saglio G, Pandolfi PP. Leukemia. 2014 Jun;28(6):1326-33. doi: 10.1038/leu.2013.370. Epub 2013 Dec 9. PubMed |
| Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016/j.cell.2013.11.037. PubMed |
| Evaluation of stromal HGF immunoreactivity as a biomarker for melanoma response to RAF inhibitors. Lezcano C, Lee CW, Larson AR, Menzies AM, Kefford RF, Thompson JF, Mihm MC Jr, Ogino S, Long GV, Scolyer RA, Murphy GF. Mod Pathol. 2014 Sep;27(9):1193-202. doi: 10.1038/modpathol.2013.226. Epub 2014 Jan 17. PubMed |
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.
Yamano K, Fogel AI, Wang C, van der Bliek AM, Youle RJ.
Elife (Cambridge). 2014 Feb 25;3:e01612. doi: 10.7554/eLife.01612.
PubMed
Associated Plasmids |
| A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity. Ablett MP, O'Brien CS, Sims AH, Farnie G, Clarke RB. Oncotarget. 2014 Feb 15;5(3):599-612. PubMed |
| ERbeta regulates NSCLC phenotypes by controlling oncogenic RAS signaling. Nikolos F, Thomas C, Rajapaksa G, Bado I, Gustafsson JA. Mol Cancer Res. 2014 Jun;12(6):843-54. doi: 10.1158/1541-7786.MCR-13-0663. Epub 2014 Mar 11. PubMed |
| A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. Serra RW, Fang M, Park SM, Hutchinson L, Green MR. Elife. 2014 Mar 12;3:e02313. doi: 10.7554/eLife.02313. PubMed |
| Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Gokturk C, Sanjiv K, Stromberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G. Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2. PubMed |
| Identification of acquired mutations by whole-genome sequencing in GATA-2 deficiency evolving into myelodysplasia and acute leukemia. Fujiwara T, Fukuhara N, Funayama R, Nariai N, Kamata M, Nagashima T, Kojima K, Onishi Y, Sasahara Y, Ishizawa K, Nagasaki M, Nakayama K, Harigae H. Ann Hematol. 2014 Sep;93(9):1515-22. doi: 10.1007/s00277-014-2090-4. Epub 2014 Apr 30. PubMed |
| A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations. Kohsaka S, Shukla N, Ameur N, Ito T, Ng CK, Wang L, Lim D, Marchetti A, Viale A, Pirun M, Socci ND, Qin LX, Sciot R, Bridge J, Singer S, Meyers P, Wexler LH, Barr FG, Dogan S, Fletcher JA, Reis-Filho JS, Ladanyi M. Nat Genet. 2014 Jun;46(6):595-600. doi: 10.1038/ng.2969. Epub 2014 May 4. PubMed |
| Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells. Gotz R, Sendtner M. PLoS One. 2014 Jun 24;9(6):e100944. doi: 10.1371/journal.pone.0100944. eCollection 2014. PubMed |
| Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. Schaeffer D, Somarelli JA, Hanna G, Palmer GM, Garcia-Blanco MA. Mol Cell Biol. 2014 Sep 15;34(18):3486-99. doi: 10.1128/MCB.00694-14. Epub 2014 Jul 7. PubMed |
| The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage response. Cao X, Kong CM, Mathi KM, Lim YP, Cacheux-Rataboul V, Wang X. BMC Biochem. 2014 Aug 7;15:17. doi: 10.1186/1471-2091-15-17. PubMed |
| The novel organic arsenical darinaparsin induces MAPK-mediated and SHP1-dependent cell death in T-cell lymphoma and Hodgkin lymphoma cells and human xenograft models. Ravi D, Bhalla S, Gartenhaus RB, Crombie J, Kandela I, Sharma J, Mazar A, Evens AM. Clin Cancer Res. 2014 Dec 1;20(23):6023-33. doi: 10.1158/1078-0432.CCR-14-1532. Epub 2014 Oct 14. PubMed |
| Metformin and erlotinib synergize to inhibit basal breast cancer. Lau YK, Du X, Rayannavar V, Hopkins B, Shaw J, Bessler E, Thomas T, Pires MM, Keniry M, Parsons RE, Cremers S, Szabolcs M, Maurer MA. Oncotarget. 2014 Nov 15;5(21):10503-17. PubMed |
| An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2. Tseng PC, Chen CL, Shan YS, Chang WT, Liu HS, Hong TM, Hsieh CY, Lin SH, Lin CF. Cell Commun Signal. 2014 Nov 15;12:69. doi: 10.1186/s12964-014-0069-3. PubMed |
| Arhgef7 promotes activation of the Hippo pathway core kinase Lats. Heidary Arash E, Song KM, Song S, Shiban A, Attisano L. EMBO J. 2014 Dec 17;33(24):2997-3011. doi: 10.15252/embj.201490230. Epub 2014 Nov 25. PubMed |
| Focus formation: a cell-based assay to determine the oncogenic potential of a gene. Alvarez A, Barisone GA, Diaz E. J Vis Exp. 2014 Dec 31;(94). doi: 10.3791/51742. PubMed |
| hTERT-immortalized ovine microglia propagate natural scrapie isolates. Munoz-Gutierrez JF, Schneider DA, Baszler TV, Greenlee JJ, Nicholson EM, Stanton JB. Virus Res. 2015 Feb 16;198:35-43. doi: 10.1016/j.virusres.2014.10.028. Epub 2015 Jan 12. PubMed |
| Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein. Kiss K, Kucsma N, Brozik A, Tusnady GE, Bergam P, van Niel G, Szakacs G. Biochem J. 2015 Apr 1;467(1):127-39. doi: 10.1042/BJ20141085. PubMed |
Rapid, specific, no-wash, far-red fluorogen activation in subcellular compartments by targeted fluorogen activating proteins.
Telmer CA, Verma R, Teng H, Andreko S, Law L, Bruchez MP.
ACS Chem Biol. 2015 May 15;10(5):1239-46. doi: 10.1021/cb500957k. Epub 2015 Feb 16.
PubMed
Associated Plasmids |
| PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function. Keskin N, Deniz E, Eryilmaz J, Un M, Batur T, Ersahin T, Cetin Atalay R, Sakaguchi S, Ellmeier W, Erman B. Mol Cell Biol. 2015 May;35(10):1741-53. doi: 10.1128/MCB.01475-14. Epub 2015 Mar 9. PubMed |
| Potent restriction of HIV-1 and SIVmac239 replication by African green monkey TRIM5alpha. Coren LV, Trivett MT, Jain S, Ayala VI, Del Prete GQ, Ohlen C, Ott DE. Retrovirology. 2015 Feb 7;12:11. doi: 10.1186/s12977-015-0137-9. PubMed |
| Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, Wendler S, Mannle D, Hinz U, Sticht C, Muciek M, Gretz N, Rose AJ, Greiner V, Hofmann TG, Bauer A, Hoheisel J, Berriel Diaz M, Gaida MM, Werner J, Schafmeier T, Strobel O, Herzig S. EMBO Mol Med. 2015 Jun 12;7(8):1048-62. doi: 10.15252/emmm.201404837. PubMed |
| Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B. Sci Signal. 2015 Jun 16;8(381):ra58. doi: 10.1126/scisignal.aaa4998. PubMed |
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