pRK5-HA-Parkin Citations (16)
Originally described in: Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM Proc Natl Acad Sci U S A 2000 Nov 21;97(24):13354-9. PubMed Journal
Articles Citing pRK5-HA-Parkin
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| Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. Kim SJ, Syed GH, Siddiqui A. PLoS Pathog. 2013 Mar;9(3):e1003285. doi: 10.1371/journal.ppat.1003285. Epub 2013 Mar 28. PubMed |
| PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis. Ito S, Araya J, Kurita Y, Kobayashi K, Takasaka N, Yoshida M, Hara H, Minagawa S, Wakui H, Fujii S, Kojima J, Shimizu K, Numata T, Kawaishi M, Odaka M, Morikawa T, Harada T, Nishimura SL, Kaneko Y, Nakayama K, Kuwano K. Autophagy. 2015;11(3):547-59. doi: 10.1080/15548627.2015.1017190. PubMed |
| Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor. Sargsyan A, Cai J, Fandino LB, Labasky ME, Forostyan T, Colosimo LK, Thompson SJ, Graham TE. Sci Rep. 2015 Jul 28;5:12397. doi: 10.1038/srep12397. PubMed |
| MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, Wu J, Xie W, Zhang Y, Xu N. Oncotarget. 2016 Jul 5;7(27):42274-42287. doi: 10.18632/oncotarget.9786. PubMed |
| A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Hammerling BC, Najor RH, Cortez MQ, Shires SE, Leon LJ, Gonzalez ER, Boassa D, Phan S, Thor A, Jimenez RE, Li H, Kitsis RN, Dorn Ii GW, Sadoshima J, Ellisman MH, Gustafsson AB. Nat Commun. 2017 Jan 30;8:14050. doi: 10.1038/ncomms14050. PubMed |
| Involvement of Parkin in the ubiquitin proteasome system-mediated degradation of N-type voltage-gated Ca2+ channels. Grimaldo L, Sandoval A, Garza-Lopez E, Felix R. PLoS One. 2017 Sep 28;12(9):e0185289. doi: 10.1371/journal.pone.0185289. eCollection 2017. PubMed |
| Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells. Pascucci B, D'Errico M, Romagnoli A, De Nuccio C, Savino M, Pietraforte D, Lanzafame M, Calcagnile AS, Fortini P, Baccarini S, Orioli D, Degan P, Visentin S, Stefanini M, Isidoro C, Fimia GM, Dogliotti E. Oncotarget. 2016 Jun 7;8(61):102852-102867. doi: 10.18632/oncotarget.9913. eCollection 2017 Nov 28. PubMed |
| Degradation of altered mitochondria by autophagy is impaired in Lafora disease. Lahuerta M, Aguado C, Sanchez-Martin P, Sanz P, Knecht E. FEBS J. 2018 Jun;285(11):2071-2090. doi: 10.1111/febs.14468. Epub 2018 Apr 23. PubMed |
| PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, Hosaka Y, Ichikawa A, Saito N, Kadota T, Yoshida M, Fujita Y, Utsumi H, Kobayashi K, Yanagisawa H, Hashimoto M, Wakui H, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K. Autophagy. 2019 Mar;15(3):510-526. doi: 10.1080/15548627.2018.1532259. Epub 2018 Oct 13. PubMed |
| Miro proteins prime mitochondria for Parkin translocation and mitophagy. Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A. EMBO J. 2019 Jan 15;38(2). pii: embj.201899384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30. PubMed |
| Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis. Saito N, Araya J, Ito S, Tsubouchi K, Minagawa S, Hara H, Ito A, Nakano T, Hosaka Y, Ichikawa A, Kadota T, Yoshida M, Fujita Y, Utsumi H, Kurita Y, Kobayashi K, Hashimoto M, Wakui H, Numata T, Kaneko Y, Asano H, Odaka M, Ohtsuka T, Morikawa T, Nakayama K, Kuwano K. J Immunol. 2019 Mar 1;202(5):1428-1440. doi: 10.4049/jimmunol.1801293. Epub 2019 Jan 28. PubMed |
| BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis. Chen Q, Lei JH, Bao J, Wang H, Hao W, Li L, Peng C, Masuda T, Miao K, Xu J, Xu X, Deng CX. Adv Sci (Weinh). 2020 Feb 14;7(6):1903616. doi: 10.1002/advs.201903616. eCollection 2020 Mar. PubMed |
Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles.
Ryan TA, Phillips EO, Collier CL, Jb Robinson A, Routledge D, Wood RE, Assar EA, Tumbarello DA.
EMBO J. 2020 Jun 2;39(11):e102539. doi: 10.15252/embj.2019102539. Epub 2020 Apr 20.
PubMed
Associated Plasmids |
| The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5. Bu L, Wang H, Hou P, Guo S, He M, Xiao J, Li P, Zhong Y, Jia P, Cao Y, Liang G, Yang C, Chen L, Guo D, Li CM. Front Immunol. 2020 Sep 2;11:1926. doi: 10.3389/fimmu.2020.01926. eCollection 2020. PubMed |
| Overexpression of Parkin in clear cell renal cell carcinoma decreases tumor aggressiveness by regulating CKS2 levels. Esser LK, Branchi V, Shakeri F, Simon AG, Stephan C, Kristiansen G, Buness A, Schorle H, Toma MI. Int J Oncol. 2022 Feb;60(2). pii: 20. doi: 10.3892/ijo.2022.5310. Epub 2022 Jan 21. PubMed |
| PARK2 regulates eIF4B-driven lymphomagenesis. Kapadia BB, Roychowdhury A, Kayastha F, Nanaji N, Gartenhaus RB. Mol Cancer Res. 2022 Feb 1. pii: 681718. doi: 10.1158/1541-7786.MCR-21-0729. PubMed |
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