pRK5-Myc-Parkin Citations (13)
Originally described in: Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM Proc Natl Acad Sci U S A 2000 Nov 21;97(24):13354-9. PubMed Journal
Articles Citing pRK5-Myc-Parkin
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| Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. Cui M, Tang X, Christian WV, Yoon Y, Tieu K. J Biol Chem. 2010 Apr 9. 285(15):11740-52. PubMed |
| Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression. Song L, Shan Y, Lloyd KC, Cortopassi GA. Hum Mol Genet. 2012 Dec 1;21(23):5147-58. doi: 10.1093/hmg/dds365. Epub 2012 Sep 4. PubMed |
Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase.
Birsa N, Norkett R, Wauer T, Mevissen TE, Wu HC, Foltynie T, Bhatia K, Hirst WD, Komander D, Plun-Favreau H, Kittler JT.
J Biol Chem. 2014 May 23;289(21):14569-82. doi: 10.1074/jbc.M114.563031. Epub 2014 Mar 26.
PubMed
Associated Plasmids |
| Calpain Determines the Propensity of Adult Hippocampal Neural Stem Cells to Autophagic Cell Death Following Insulin Withdrawal. Chung KM, Park H, Jung S, Ha S, Yoo SJ, Woo H, Lee HJ, Kim SW, Kim EK, Moon C, Yu SW. Stem Cells. 2015 Jun 18. doi: 10.1002/stem.2082. PubMed |
| A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Hammerling BC, Najor RH, Cortez MQ, Shires SE, Leon LJ, Gonzalez ER, Boassa D, Phan S, Thor A, Jimenez RE, Li H, Kitsis RN, Dorn Ii GW, Sadoshima J, Ellisman MH, Gustafsson AB. Nat Commun. 2017 Jan 30;8:14050. doi: 10.1038/ncomms14050. PubMed |
| Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin. Hammerling BC, Shires SE, Leon LJ, Cortez MQ, Gustafsson AB. Small GTPases. 2020 Jan;11(1):69-76. doi: 10.1080/21541248.2017.1342749. Epub 2017 Sep 18. PubMed |
| Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons. Zhu M, Cortese GP, Waites CL. BMC Biol. 2018 Sep 10;16(1):100. doi: 10.1186/s12915-018-0567-7. PubMed |
| Tanycytic TSPO inhibition induces lipophagy to regulate lipid metabolism and improve energy balance. Kim S, Kim N, Park S, Jeon Y, Lee J, Yoo SJ, Lee JW, Moon C, Yu SW, Kim EK. Autophagy. 2019 Aug 30:1-21. doi: 10.1080/15548627.2019.1659616. PubMed |
| Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells. Lim Y, Kim S, Kim EK. Mol Brain. 2021 Apr 6;14(1):65. doi: 10.1186/s13041-021-00777-8. PubMed |
| MAPK15 protects from oxidative stress-dependent cellular senescence by inducing the mitophagic process. Franci L, Tubita A, Bertolino FM, Palma A, Cannino G, Settembre C, Rasola A, Rovida E, Chiariello M. Aging Cell. 2022 Jul;21(7):e13620. doi: 10.1111/acel.13620. Epub 2022 Jun 1. PubMed |
| Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Kocaturk NM, Peker N, Eberhart K, Akkoc Y, Deveci G, Dengjel J, Gozuacik D. Cell Death Dis. 2022 Nov 10;13(11):947. doi: 10.1038/s41419-022-05339-x. PubMed |
| Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy. Quiles JM, Najor RH, Gonzalez E, Jeung M, Liang W, Burbach SM, Zumaya EA, Diao RY, Lampert MA, Gustafsson AB. Sci Signal. 2023 Jan 31;16(770):eabo4457. doi: 10.1126/scisignal.abo4457. Epub 2023 Jan 31. PubMed |
| Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms. Botta S, de Prisco N, Chemiakine A, Brandt V, Cabaj M, Patel P, Doron-Mandel E, Treadway CJ, Jovanovic M, Brown NG, Soni RK, Gennarino VA. EMBO J. 2023 Jun 1;42(11):e112721. doi: 10.15252/embj.2022112721. Epub 2023 Apr 18. PubMed |
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