pLenti CMV TetR Blast (716-1) Citations (42)
Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal
Articles Citing pLenti CMV TetR Blast (716-1)
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Necdin modulates proliferative cell survival of human cells in response to radiation-induced genotoxic stress. Lafontaine J, Tchakarska G, Rodier F, Mes-Masson AM. BMC Cancer. 2012 Jun 12;12:234. doi: 10.1186/1471-2407-12-234. PubMed |
Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains. Miyagawa-Yamaguchi A, Kotani N, Honke K. PLoS One. 2014 Mar 26;9(3):e93054. doi: 10.1371/journal.pone.0093054. eCollection 2014. PubMed |
Oncogene-like induction of cellular invasion from centrosome amplification. Godinho SA, Picone R, Burute M, Dagher R, Su Y, Leung CT, Polyak K, Brugge JS, Thery M, Pellman D. Nature. 2014 Jun 5;510(7503):167-71. doi: 10.1038/nature13277. Epub 2014 Apr 13. PubMed |
Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines. Wang B, Lee CW, Witt A, Thakkar A, Ince TA. Breast Cancer Res Treat. 2015 Aug;153(1):57-66. doi: 10.1007/s10549-015-3521-1. Epub 2015 Jul 30. PubMed |
PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells. de Araujo WM, Robbs BK, Bastos LG, de Souza WF, Vidal FC, Viola JP, Morgado-Diaz JA. J Cell Biochem. 2016 Feb;117(2):458-69. doi: 10.1002/jcb.25294. PubMed |
TrkA is amplified in malignant melanoma patients and induces an anti-proliferative response in cell lines. Pasini L, Re A, Tebaldi T, Ricci G, Boi S, Adami V, Barbareschi M, Quattrone A. BMC Cancer. 2015 Oct 24;15:777. doi: 10.1186/s12885-015-1791-y. PubMed |
Using Cell Culture Models of Centrosome Amplification to Study Centrosome Clustering in Cancer. Kwon M. Methods Mol Biol. 2016;1413:367-92. doi: 10.1007/978-1-4939-3542-0_23. PubMed |
Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity. Kohnz RA, Roberts LS, DeTomaso D, Bideyan L, Yan P, Bandyopadhyay S, Goga A, Yosef N, Nomura DK. ACS Chem Biol. 2016 Aug 19;11(8):2131-9. doi: 10.1021/acschembio.6b00433. Epub 2016 Jul 22. PubMed |
CD63 regulates Epstein-Barr virus LMP1 exosomal packaging, enhancement of vesicle production, and non-canonical NF-kappaB signaling. Hurwitz SN, Nkosi D, Conlon MM, York SB, Liu X, Tremblay DC, Meckes DG Jr. J Virol. 2016 Dec 14. pii: JVI.02251-16. PubMed |
Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules. Grabocka E, Bar-Sagi D. Cell. 2016 Dec 15;167(7):1803-1813.e12. doi: 10.1016/j.cell.2016.11.035. PubMed |
Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC.
Frank SB, Berger PL, Ljungman M, Miranti CK.
J Cell Sci. 2017 Apr 26. pii: jcs.197152. doi: 10.1242/jcs.197152.
PubMed
Associated Plasmids |
Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, Zasso J, Conti L, Demichelis F, Cereseto A. Nat Commun. 2017 May 22;8:15334. doi: 10.1038/ncomms15334. PubMed |
Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. Rhys AD, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, Leitinger B, Sahai E, McAinsh A, Charras G, Godinho SA. J Cell Biol. 2018 Jan 2;217(1):195-209. doi: 10.1083/jcb.201704102. Epub 2017 Nov 13. PubMed |
Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation. Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwinska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B. Oncotarget. 2017 Jun 30;8(47):82123-82143. doi: 10.18632/oncotarget.18899. eCollection 2017 Oct 10. PubMed |
Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1 Hurwitz SN, Cheerathodi MR, Nkosi D, York SB, Meckes DG Jr. J Virol. 2018 Feb 12;92(5). pii: JVI.01969-17. doi: 10.1128/JVI.01969-17. Print 2018 Mar 1. PubMed |
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA.
Dev Cell. 2018 Jan 8;44(1):97-112.e7. doi: 10.1016/j.devcel.2017.11.020. Epub 2017 Dec 21.
PubMed
Associated Plasmids |
The interactome of EBV LMP1 evaluated by proximity-based BioID approach. Rider MA, Cheerathodi MR, Hurwitz SN, Nkosi D, Howell LA, Tremblay DC, Liu X, Zhu F, Meckes DG Jr. Virology. 2018 Mar;516:55-70. doi: 10.1016/j.virol.2017.12.033. Epub 2018 Jan 9. PubMed |
Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Kwasna D, Abdul Rehman SA, Natarajan J, Matthews S, Madden R, De Cesare V, Weidlich S, Virdee S, Ahel I, Gibbs-Seymour I, Kulathu Y. Mol Cell. 2018 Apr 5;70(1):150-164.e6. doi: 10.1016/j.molcel.2018.02.023. Epub 2018 Mar 22. PubMed |
Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Arnandis T, Monteiro P, Adams SD, Bridgeman VL, Rajeeve V, Gadaleta E, Marzec J, Chelala C, Malanchi I, Cutillas PR, Godinho SA. Dev Cell. 2018 Nov 19;47(4):409-424.e9. doi: 10.1016/j.devcel.2018.10.026. PubMed |
Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition. Augert A, Eastwood E, Ibrahim AH, Wu N, Grunblatt E, Basom R, Liggitt D, Eaton KD, Martins R, Poirier JT, Rudin CM, Milletti F, Cheng WY, Mack F, MacPherson D. Sci Signal. 2019 Feb 5;12(567). pii: 12/567/eaau2922. doi: 10.1126/scisignal.aau2922. PubMed |
Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Baron DM, Matheny T, Lin YC, Leszyk JD, Kenna K, Gall KV, Santos DP, Tischbein M, Funes S, Hayward LJ, Kiskinis E, Landers JE, Parker R, Shaffer SA, Bosco DA. Hum Mol Genet. 2019 Jul 1;28(13):2143-2160. doi: 10.1093/hmg/ddz048. PubMed |
Modelling the MYC-driven normal-to-tumour switch in breast cancer. Lourenco C, Kalkat M, Houlahan KE, De Melo J, Longo J, Done SJ, Boutros PC, Penn LZ. Dis Model Mech. 2019 Jul 26;12(7). pii: 12/7/dmm038083. doi: 10.1242/dmm.038083. PubMed |
Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth. Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF. Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. doi: 10.1016/j.celrep.2019.07.031. PubMed |
Notch3 promotes prostate cancer-induced bone lesion development via MMP-3. Ganguly SS, Hostetter G, Tang L, Frank SB, Saboda K, Mehra R, Wang L, Li X, Keller ET, Miranti CK. Oncogene. 2020 Jan;39(1):204-218. doi: 10.1038/s41388-019-0977-1. Epub 2019 Aug 29. PubMed |
LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors. Corallo D, Donadon M, Pantile M, Sidarovich V, Cocchi S, Ori M, De Sarlo M, Candiani S, Frasson C, Distel M, Quattrone A, Zanon C, Basso G, Tonini GP, Aveic S. Cell Death Differ. 2020 Apr;27(4):1225-1242. doi: 10.1038/s41418-019-0425-3. Epub 2019 Oct 10. PubMed |
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. PubMed |
APOBEC3A is a prominent cytidine deaminase in breast cancer. Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA. PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec. PubMed |
E2F7 is a potent inhibitor of liver tumor growth in adult mice. Moreno E, Toussaint MJM, van Essen SC, Bongiovanni L, van Liere EA, Koster MH, Yuan R, van Deursen J, Westendorp B, de Bruin A. Hepatology. 2020 Apr 7. doi: 10.1002/hep.31259. PubMed |
Epstein-Barr Virus LMP1 Promotes Syntenin-1- and Hrs-Induced Extracellular Vesicle Formation for Its Own Secretion To Increase Cell Proliferation and Migration. Nkosi D, Sun L, Duke LC, Patel N, Surapaneni SK, Singh M, Meckes DG Jr. mBio. 2020 Jun 16;11(3). pii: mBio.00589-20. doi: 10.1128/mBio.00589-20. PubMed |
Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles. Cone AS, Hurwitz SN, Lee GS, Yuan X, Zhou Y, Li Y, Meckes DG Jr. BMC Mol Cell Biol. 2020 Jul 30;21(1):58. doi: 10.1186/s12860-020-00302-0. PubMed |
Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo. Lopez-Lopez E, Autry RJ, Smith C, Yang W, Paugh SW, Panetta JC, Crews KR, Bonten EJ, Smart B, Pei D, McCorkle JR, Diouf B, Roberts KG, Shi L, Pounds S, Cheng C, Mullighan CG, Pui CH, Relling MV, Evans WE. J Clin Invest. 2020 Dec 1;130(12):6600-6615. doi: 10.1172/JCI140797. PubMed |
Single-strand DNA breaks cause replisome disassembly. Vrtis KB, Dewar JM, Chistol G, Wu RA, Graham TGW, Walter JC. Mol Cell. 2021 Mar 18;81(6):1309-1318.e6. doi: 10.1016/j.molcel.2020.12.039. Epub 2021 Jan 22. PubMed |
Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption. Adams SD, Csere J, D'angelo G, Carter EP, Romao M, Arnandis T, Dodel M, Kocher HM, Grose R, Raposo G, Mardakheh F, Godinho SA. Curr Biol. 2021 Apr 12;31(7):1403-1416.e7. doi: 10.1016/j.cub.2021.01.028. Epub 2021 Feb 15. PubMed |
Zika Virus Hijacks Extracellular Vesicle Tetraspanin Pathways for Cell-to-Cell Transmission. York SB, Sun L, Cone AS, Duke LC, Cheerathodi MR, Meckes DG Jr. mSphere. 2021 Jun 30:e0019221. doi: 10.1128/mSphere.00192-21. PubMed |
Identification of new ETV6 modulators through a high-throughput functional screening. Neveu B, Richer C, Cassart P, Caron M, Jimenez-Cortes C, St-Onge P, Fuchs C, Garnier N, Gobeil S, Sinnett D. iScience. 2022 Feb 2;25(3):103858. doi: 10.1016/j.isci.2022.103858. eCollection 2022 Mar 18. PubMed |
CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor. Zou C, Beard JA, Yang G, Evans WE, Bonten EJ. J Inflamm Res. 2022 Feb 19;15:1183-1194. doi: 10.2147/JIR.S333725. eCollection 2022. PubMed |
Inactivation of the Hippo tumor suppressor pathway promotes melanoma. Vittoria MA, Kingston N, Kotynkova K, Xia E, Hong R, Huang L, McDonald S, Tilston-Lunel A, Darp R, Campbell JD, Lang D, Xu X, Ceol CJ, Varelas X, Ganem NJ. Nat Commun. 2022 Jun 29;13(1):3732. doi: 10.1038/s41467-022-31399-w. PubMed |
Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis. Darp R, Vittoria MA, Ganem NJ, Ceol CJ. Nat Commun. 2022 Jul 15;13(1):4109. doi: 10.1038/s41467-022-31899-9. PubMed |
Rho activation drives luminal collapse and eversion in epithelial acini. Narayanan V, Purkayastha P, Yu B, Pendyala K, Chukkapalli S, Cabe JI, Dickinson RB, Conway DE, Lele TP. Biophys J. 2023 Jan 7:S0006-3495(23)00005-X. doi: 10.1016/j.bpj.2023.01.005. PubMed |
Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies. Kumar MS, Stallworth KM, Murthy AC, Lim SM, Li N, Jain A, Munro JB, Fawzi NL, Lagier-Tourenne C, Bosco DA. J Mol Biol. 2023 Mar 15;435(6):167972. doi: 10.1016/j.jmb.2023.167972. Epub 2023 Jan 21. PubMed |
FAM193A is a positive regulator of p53 activity. Szwarc MM, Guarnieri AL, Joshi M, Duc HN, Laird MC, Pandey A, Khanal S, Dohm E, Bui AK, Sullivan KD, Galbraith MD, Andrysik Z, Espinosa JM. Cell Rep. 2023 Mar 28;42(3):112230. doi: 10.1016/j.celrep.2023.112230. Epub 2023 Mar 9. PubMed |
CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. Eibes S, Rajendraprasad G, Guasch-Boldu C, Kubat M, Steblyanko Y, Barisic M. Nat Commun. 2023 Sep 1;14(1):5317. doi: 10.1038/s41467-023-41091-2. PubMed |
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