pLenti CMV Blast DEST (706-1) Citations (54)
Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal
Articles Citing pLenti CMV Blast DEST (706-1)
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| IL4 limits the efficacy of tumor-targeted antibody therapy in a murine model. Surana R, Wang S, Xu W, Jablonski SA, Weiner LM. Cancer Immunol Res. 2014 Nov;2(11):1103-12. doi: 10.1158/2326-6066.CIR-14-0103. Epub 2014 Sep 9. PubMed |
| Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia. Sujobert P, Poulain L, Paubelle E, Zylbersztejn F, Grenier A, Lambert M, Townsend EC, Brusq JM, Nicodeme E, Decrooqc J, Nepstad I, Green AS, Mondesir J, Hospital MA, Jacque N, Christodoulou A, Desouza TA, Hermine O, Foretz M, Viollet B, Lacombe C, Mayeux P, Weinstock DM, Moura IC, Bouscary D, Tamburini J. Cell Rep. 2015 Jun 9;11(9):1446-57. doi: 10.1016/j.celrep.2015.04.063. Epub 2015 May 21. PubMed |
| Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line. Sluch VM, Davis CH, Ranganathan V, Kerr JM, Krick K, Martin R, Berlinicke CA, Marsh-Armstrong N, Diamond JS, Mao HQ, Zack DJ. Sci Rep. 2015 Nov 13;5:16595. doi: 10.1038/srep16595. PubMed |
| FAT1 mutations cause a glomerulotubular nephropathy. Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LG, ffrench-Constant C, Allen N, McNeill H, Buscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NE, Walz G, Tufro A, Hildebrandt F. Nat Commun. 2016 Feb 24;7:10822. doi: 10.1038/ncomms10822. PubMed |
| Viral FGARAT Homolog ORF75 of Rhesus Monkey Rhadinovirus Effects Proteasomal Degradation of the ND10 Components SP100 and PML. Hahn AS, Grosskopf AK, Jungnickl D, Scholz B, Ensser A. J Virol. 2016 Aug 12;90(17):8013-28. doi: 10.1128/JVI.01181-16. Print 2016 Sep 1. PubMed |
| p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1. Al-Khalaf HH, Aboussekhra A. Mol Carcinog. 2016 Sep 6. doi: 10.1002/mc.22564. PubMed |
| Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov. PubMed |
| Potent EMT and CSC Phenotypes are Induced by Oncostatin-M in Pancreatic Cancer. Smigiel JM, Parameswaran N, Jackson MW. Mol Cancer Res. 2017 Jan 4. pii: molcanres.0337.2016. doi: 10.1158/1541-7786.MCR-16-0337. PubMed |
| Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Moniz LS, Surinova S, Ghazaly E, Velasco LG, Haider S, Rodriguez-Prados JC, Berenjeno IM, Chelala C, Vanhaesebroeck B. Sci Rep. 2017 Jan 6;7:39985. doi: 10.1038/srep39985. PubMed |
| TP53INP1 down-regulation activates a p73-dependent DUSP10/ERK signaling pathway to promote metastasis of hepatocellular carcinoma. Ng KY, Chan LH, Chai S, Tong M, Guan XY, Lee NP, Yuan Y, Xie D, Lee TK, Dusetti NJ, Carrier A, Ma S. Cancer Res. 2017 Jul 3. pii: canres.3456.2016. doi: 10.1158/0008-5472.CAN-16-3456. PubMed |
| Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA. PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct. PubMed |
| Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE. Nat Cell Biol. 2017 Dec;19(12):1412-1423. doi: 10.1038/ncb3631. Epub 2017 Oct 30. PubMed |
| ERAD-dependent control of the Wnt secretory factor Evi. Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, Christianson JC, Boutros M. EMBO J. 2018 Feb 15;37(4). pii: embj.201797311. doi: 10.15252/embj.201797311. Epub 2018 Jan 29. PubMed |
| Membrane detachment is not essential for COG complex function. Climer LK, Pokrovskaya ID, Blackburn JB, Lupashin VV. Mol Biol Cell. 2018 Apr 15;29(8):964-974. doi: 10.1091/mbc.E17-11-0694. Epub 2018 Mar 30. PubMed |
| PGC-1alpha Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, Luo X, Hong C, Lin J, Wang CY. Cell Stem Cell. 2018 Aug 2;23(2):193-209.e5. doi: 10.1016/j.stem.2018.06.009. Epub 2018 Jul 12. PubMed |
| Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation. Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nahse V, Carlson A, Brech A, Stenmark H, Raiborg C. Nat Commun. 2018 Jul 26;9(1):2932. doi: 10.1038/s41467-018-05345-8. PubMed |
| Microcystin-LR promotes migration via the cooperation between microRNA-221/PTEN and STAT3 signal pathway in colon cancer cell line DLD-1. Ren Y, Yang M, Ma R, Gong Y, Zou Y, Wang T, Wu J. Ecotoxicol Environ Saf. 2019 Jan 15;167:107-113. doi: 10.1016/j.ecoenv.2018.09.065. Epub 2018 Oct 9. PubMed |
| Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB. Nat Commun. 2018 Oct 22;9(1):4385. doi: 10.1038/s41467-018-06854-2. PubMed |
| Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis. O'Farrell H, Harbourne B, Kurlawala Z, Inoue Y, Nagelberg AL, Martinez VD, Lu D, Oh MH, Coe BP, Thu KL, Somwar R, Lam S, Lam WL, Unni AM, Beverly L, Lockwood WW. J Thorac Oncol. 2019 Apr;14(4):656-671. doi: 10.1016/j.jtho.2018.12.004. Epub 2018 Dec 19. PubMed |
| STF-62247 accumulates in lysosomes and blocks late stages of autophagy to selectively target von Hippel-Lindau-inactivated cells. Bouhamdani N, Comeau D, Cormier K, Turcotte S. Am J Physiol Cell Physiol. 2019 May 1;316(5):C605-C620. doi: 10.1152/ajpcell.00483.2018. Epub 2019 Feb 13. PubMed |
| Egr2 overexpression in Schwann cells increases myelination frequency in vitro. Tammia M, Mi R, Sluch VM, Zhu A, Chung T, Shinn D, Zack DJ, Hoke A, Mao HQ. Heliyon. 2018 Nov 29;4(11):e00982. doi: 10.1016/j.heliyon.2018.e00982. eCollection 2018 Nov. PubMed |
| Development of a Synthetic 3-ketosteroid Delta(1)-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells. D'Arcy BM, Swingle MR, Schambeau L, Pannell L, Prakash A, Honkanen RE. Sci Rep. 2019 Apr 12;9(1):5969. doi: 10.1038/s41598-019-42046-8. PubMed |
| MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy. Bugiardini E, Mitchell AL, Rosa ID, Horning-Do HT, Pitmann A, Poole OV, Holton JL, Shah S, Woodward C, Hargreaves I, Quinlivan R, Amunts A, Wiesner RJ, Houlden H, Holt IJ, Hanna MG, Pitceathly RDS, Spinazzola A. Hum Mol Genet. 2019 Apr 30. pii: 5482278. doi: 10.1093/hmg/ddz093. PubMed |
| Acquired MET Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in EGFR-Mutated Lung Cancer. Suzawa K, Offin M, Schoenfeld AJ, Plodkowski AJ, Odintsov I, Lu D, Lockwood WW, Arcila ME, Rudin CM, Drilon A, Yu HA, Riely GJ, Somwar R, Ladanyi M. JCO Precis Oncol. 2019;3. doi: 10.1200/PO.19.00011. Epub 2019 May 10. PubMed |
| SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PHL, Flynn RL, Boulton SJ. Mol Cell. 2019 Oct 3;76(1):27-43.e11. doi: 10.1016/j.molcel.2019.07.010. Epub 2019 Aug 22. PubMed |
Dualism of FGF and TGF-beta Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant.
Bordignon P, Bottoni G, Xu X, Popescu AS, Truan Z, Guenova E, Kofler L, Jafari P, Ostano P, Rocken M, Neel V, Dotto GP.
Cell Rep. 2019 Aug 27;28(9):2358-2372.e6. doi: 10.1016/j.celrep.2019.07.092.
PubMed
Associated Plasmids |
| Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Gomes AP, Ilter D, Low V, Rosenzweig A, Shen ZJ, Schild T, Rivas MA, Er EE, McNally DR, Mutvei AP, Han J, Ou YH, Cavaliere P, Mullarky E, Nagiec M, Shin S, Yoon SO, Dephoure N, Massague J, Melnick AM, Cantley LC, Tyler JK, Blenis J. Cancer Cell. 2019 Oct 14;36(4):402-417.e13. doi: 10.1016/j.ccell.2019.08.006. Epub 2019 Sep 26. PubMed |
| A molecular mechanism underlying genotype-specific intrahepatic cholestasis resulting from MYO5B mutations. Overeem AW, Li Q, Qiu YL, Carton-Garcia F, Leng C, Klappe K, Dronkers J, Hsiao NH, Wang JS, Arango D, van IJzendoorn SCD. Hepatology. 2019 Nov 21. doi: 10.1002/hep.31002. PubMed |
| Integrin alpha5 promotes migration and cisplatin resistance in esophageal squamous cell carcinoma cells. Hou S, Jin W, Xiao W, Deng B, Wu D, Zhi J, Wu K, Cao X, Chen S, Ding Y, Shi H. Am J Cancer Res. 2019 Dec 1;9(12):2774-2788. eCollection 2019. PubMed |
Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnacion-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC.
Cancer Discov. 2020 Apr 27. pii: 2159-8290.CD-19-0959. doi: 10.1158/2159-8290.CD-19-0959.
PubMed
Associated Plasmids |
| Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion. Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C. J Cell Biol. 2020 Aug 3;219(8). pii: 151827. doi: 10.1083/jcb.202003063. PubMed |
| IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice. Richardson LG, Nieman LT, Stemmer-Rachamimov AO, Zheng XS, Stafford K, Nagashima H, Miller JJ, Kiyokawa J, Ting DT, Wakimoto H, Cahill DP, Choi BD, Curry WT. Oncoimmunology. 2020 Aug 20;9(1):1806662. doi: 10.1080/2162402X.2020.1806662. PubMed |
| Sulfated glycans engage the Ang-Tie pathway to regulate vascular development. Griffin ME, Sorum AW, Miller GM, Goddard WA 3rd, Hsieh-Wilson LC. Nat Chem Biol. 2021 Feb;17(2):178-186. doi: 10.1038/s41589-020-00657-7. Epub 2020 Oct 5. PubMed |
| Allele-Specific Role of ERBB2 in the Oncogenic Function of EGFR L861Q in EGFR-Mutant Lung Cancers. Sato H, Offin M, Kubota D, Yu HA, Wilhelm C, Toyooka S, Somwar R, Kris MG, Ladanyi M. J Thorac Oncol. 2021 Jan;16(1):113-126. doi: 10.1016/j.jtho.2020.09.019. Epub 2020 Oct 7. PubMed |
| Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression. Ulukan B, Bihorac A, Sipahioglu T, Kiraly R, Fesus L, Telci D. ACS Omega. 2020 Oct 20;5(43):28273-28284. doi: 10.1021/acsomega.0c04226. eCollection 2020 Nov 3. PubMed |
| Lineage tracing and analog recording in mammalian cells by single-site DNA writing. Loveless TB, Grotts JH, Schechter MW, Forouzmand E, Carlson CK, Agahi BS, Liang G, Ficht M, Liu B, Xie X, Liu CC. Nat Chem Biol. 2021 Jun;17(6):739-747. doi: 10.1038/s41589-021-00769-8. Epub 2021 Mar 22. PubMed |
| Caspase-9 acts as a regulator of necroptotic cell death. Molnar T, Pallagi P, Tel B, Kiraly R, Csoma E, Jenei V, Varga Z, Gogolak P, Odile Hueber A, Mate Z, Erdelyi F, Szabo G, Pettko-Szandtner A, Bacsi A, Virag L, Maleth J, Koncz G. FEBS J. 2021 Apr 25. doi: 10.1111/febs.15898. PubMed |
| HOTAIR lncRNA promotes epithelial-mesenchymal transition by redistributing LSD1 at regulatory chromatin regions. Jarroux J, Foretek D, Bertrand C, Gabriel M, Szachnowski U, Saci Z, Guo S, Londono-Vallejo A, Pinskaya M, Morillon A. EMBO Rep. 2021 Jul 5;22(7):e50193. doi: 10.15252/embr.202050193. Epub 2021 May 6. PubMed |
| NEIL3 Prevents Senescence in Hepatocellular Carcinoma by Repairing Oxidative Lesions at Telomeres during Mitosis. Zhao Z, Gad H, Benitez-Buelga C, Sanjiv K, Xiangwei H, Kang H, Feng M, Zhao Z, Berglund UW, Xia Q, Helleday T. Cancer Res. 2021 Aug 1;81(15):4079-4093. doi: 10.1158/0008-5472.CAN-20-1028. Epub 2021 May 27. PubMed |
| TBX2, a Novel Regulator of Labour. Fernando F, Veenboer GJM, Oudijk MA, Kampman MAM, Heida KY, Lagendijk LJM, van der Post JAM, Jongejan A, Afink GB, Ris-Stalpers C. Medicina (Kaunas). 2021 May 21;57(6). pii: medicina57060515. doi: 10.3390/medicina57060515. PubMed |
| Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity. LaCroix R, Lin B, Kang TY, Levchenko A. Elife. 2022 Feb 24;11. pii: 66869. doi: 10.7554/eLife.66869. PubMed |
| Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer. Kakarla M, ChallaSivaKanaka S, Dufficy MF, Gil V, Filipovich Y, Vickman R, Crawford SE, Hayward SW, Franco OE. Cancers (Basel). 2022 May 9;14(9). pii: cancers14092336. doi: 10.3390/cancers14092336. PubMed |
| Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation. Aslam MS, Aslam MS, Aslam KS, Iqbal A, Yuan L. Biomed Res Int. 2022 May 29;2022:1557010. doi: 10.1155/2022/1557010. eCollection 2022. PubMed |
| Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment. Morimoto Y, Fushimi A, Yamashita N, Hagiwara M, Bhattacharya A, Cheng J, Frost TC, Ahmad R, Daimon T, Huang L, Hata T, Takahashi H, Yamamoto M, Suzuki Y, DeCaprio JA, Kufe D. Oncogene. 2022 Jul;41(27):3511-3523. doi: 10.1038/s41388-022-02361-3. Epub 2022 Jun 10. PubMed |
| YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma. Frost TC, Gartin AK, Liu M, Cheng J, Dharaneeswaran H, Keskin DB, Wu CJ, Giobbie-Hurder A, Thakuria M, DeCaprio JA. J Clin Invest. 2023 Mar 1;133(5):e157171. doi: 10.1172/JCI157171. PubMed |
| ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. Wong TL, Loh JJ, Lu S, Yan HHN, Siu HC, Xi R, Chan D, Kam MJF, Zhou L, Tong M, Copland JA, Chen L, Yun JP, Leung SY, Ma S. Nat Commun. 2023 May 19;14(1):2861. doi: 10.1038/s41467-023-38581-8. PubMed |
Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signalling.
Zeghal M, Matte K, Venes A, Patel S, Laroche G, Sarvan S, Joshi M, Rain JC, Couture JF, Giguere PM.
J Biol Chem. 2023 Jul 28:105107. doi: 10.1016/j.jbc.2023.105107.
PubMed
Associated Plasmids |
| MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC. Haratake N, Ozawa H, Morimoto Y, Yamashita N, Daimon T, Bhattacharya A, Wang K, Nakashoji A, Isozaki H, Shimokawa M, Kikutake C, Suyama M, Hashinokuchi A, Takada K, Takenaka T, Yoshizumi T, Mitsudomi T, Hata AN, Kufe D. J Thorac Oncol. 2024 Mar;19(3):434-450. doi: 10.1016/j.jtho.2023.10.017. Epub 2023 Nov 3. PubMed |
| A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness. Langsten KL, Shi L, Wilson AS, Lumia S, Westwood B, Skeen AM, Xie MT, Surratt VE, Turner J, Langefeld CD, Singh R, Cook KL, Kerr BA. Cancers (Basel). 2023 Dec 9;15(24):5773. doi: 10.3390/cancers15245773. PubMed |
| Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs. Lumeau A, Bery N, Frances A, Gayral M, Labrousse G, Ribeyre C, Lopez C, Nevot A, El Kaoutari A, Hanoun N, Sarot E, Perrier M, Pont F, Cerapio JP, Fournie JJ, Lopez F, Madrid-Mencia M, Pancaldi V, Pillaire MJ, Bergoglio V, Torrisani J, Dusetti N, Hoffmann JS, Buscail L, Lutzmann M, Cordelier P. Cancer Res. 2024 Apr 1;84(7):1013-1028. doi: 10.1158/0008-5472.CAN-22-3219. PubMed |
| NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma Tumor Growth. Cai C, Tu J, Najarro J, Zhang R, Fan H, Zhang FQ, Li J, Xie Z, Su R, Dong L, Arellano N, Ciboddo M, Elf SE, Gao X, Chen J, Wu R. Mol Cancer Res. 2024 Apr 2;22(4):386-401. doi: 10.1158/1541-7786.MCR-23-0445. PubMed |
| SHIP inhibition mediates select TREM2-induced microglial functions. Ramakrishnan GS, Berry WL, Pacherille A, Kerr WG, Chisholm JD, Pedicone C, Humphrey MB. Mol Immunol. 2024 Jun;170:35-45. doi: 10.1016/j.molimm.2024.04.002. Epub 2024 Apr 12. PubMed |
| Identification of MUC1-C as a Target for Suppressing Progression of Head and Neck Squamous Cell Carcinomas. Nakashoji A, Haratake N, Bhattacharya A, Mao W, Xu K, Wang K, Daimon T, Ozawa H, Shigeta K, Fushimi A, Yamashita N, Morimoto Y, Shimokawa M, Saito S, Egloff AM, Uppaluri R, Long MD, Kufe D. Cancer Res Commun. 2024 May 14;4(5):1268-1281. doi: 10.1158/2767-9764.CRC-24-0011. PubMed |
| Ribonuclease inhibitor and angiogenin system regulates cell type-specific global translation. Stillinovic M, Sarangdhar MA, Andina N, Tardivel A, Greub F, Bombaci G, Ansermet C, Zatti M, Saha D, Xiong J, Sagae T, Yokogawa M, Osawa M, Heller M, Keogh A, Keller I, Angelillo-Scherrer A, Allam R. Sci Adv. 2024 May 31;10(22):eadl0320. doi: 10.1126/sciadv.adl0320. Epub 2024 May 31. PubMed |
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