MSCV-IRES-Thy1.1 DEST Citations (31)
Originally described in: FOXP3 controls regulatory T cell function through cooperation with NFAT.Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A Cell. 2006 Jul 28. 126(2):375-87. PubMed Journal
Articles Citing MSCV-IRES-Thy1.1 DEST
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| BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Roychoudhuri R, Hirahara K, Mousavi K, Clever D, Klebanoff CA, Bonelli M, Sciume G, Zare H, Vahedi G, Dema B, Yu Z, Liu H, Takahashi H, Rao M, Muranski P, Crompton JG, Punkosdy G, Bedognetti D, Wang E, Hoffmann V, Rivera J, Marincola FM, Nakamura A, Sartorelli V, Kanno Y, Gattinoni L, Muto A, Igarashi K, O'Shea JJ, Restifo NP. Nature. 2013 Jun 27;498(7455):506-10. doi: 10.1038/nature12199. Epub 2013 Jun 2. PubMed |
| Synergistic anticancer effects of Pam3CSK4 and Ara-C on B-cell lymphoma cells. Lee SK, Chwee JY, Ma CA, Le Bert N, Huang CW, Gasser S. Clin Cancer Res. 2014 Jul 1;20(13):3485-95. doi: 10.1158/1078-0432.CCR-13-2522. Epub 2014 May 5. PubMed |
| Autophagy is essential for effector CD8(+) T cell survival and memory formation. Xu X, Araki K, Li S, Han JH, Ye L, Tan WG, Konieczny BT, Bruinsma MW, Martinez J, Pearce EL, Green DR, Jones DP, Virgin HW, Ahmed R. Nat Immunol. 2014 Dec;15(12):1152-61. doi: 10.1038/ni.3025. Epub 2014 Nov 2. PubMed |
| Foxp3 is a key downstream regulator of p53-mediated cellular senescence. Kim JE, Shin JS, Moon JH, Hong SW, Jung DJ, Kim JH, Hwang IY, Shin YJ, Gong EY, Lee DH, Kim SM, Lee EY, Kim YS, Kim D, Hur D, Kim TW, Kim KP, Jin DH, Lee WJ. Oncogene. 2016 May 30. doi: 10.1038/onc.2016.193. PubMed |
| A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells. Liu WH, Kang SG, Huang Z, Wu CJ, Jin HY, Maine CJ, Liu Y, Shepherd J, Sabouri-Ghomi M, Gonzalez-Martin A, Xu S, Hoffmann A, Zheng Y, Lu LF, Xiao N, Fu G, Xiao C. J Exp Med. 2016 Aug 22;213(9):1901-19. doi: 10.1084/jem.20160204. Epub 2016 Aug 1. PubMed |
| TGF-beta Controls the Formation of Kidney-Resident T Cells via Promoting Effector T Cell Extravasation. Ma C, Mishra S, Demel EL, Liu Y, Zhang N. J Immunol. 2017 Jan 15;198(2):749-756. doi: 10.4049/jimmunol.1601500. Epub 2016 Nov 30. PubMed |
| Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Adams WC, Chen YH, Kratchmarov R, Yen B, Nish SA, Lin WW, Rothman NJ, Luchsinger LL, Klein U, Busslinger M, Rathmell JC, Snoeck HW, Reiner SL. Cell Rep. 2016 Dec 20;17(12):3142-3152. doi: 10.1016/j.celrep.2016.11.065. PubMed |
| Coordination of Myeloid Differentiation with Reduced Cell Cycle Progression by PU.1 Induction of MicroRNAs Targeting Cell Cycle Regulators and Lipid Anabolism. Solomon LA, Podder S, He J, Jackson-Chornenki NL, Gibson K, Ziliotto RG, Rhee J, DeKoter RP. Mol Cell Biol. 2017 May 2;37(10). pii: MCB.00013-17. doi: 10.1128/MCB.00013-17. Print 2017 May 15. PubMed |
| BATF regulates the expression of Nfil3, Wnt10a and miR155hg for efficient induction of antibody class switch recombination in mice. Morman RE, Schweickert PG, Konieczny SF, Taparowsky EJ. Eur J Immunol. 2018 Sep;48(9):1492-1505. doi: 10.1002/eji.201747360. Epub 2018 Jun 26. PubMed |
| Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade. Hsu J, Hodgins JJ, Marathe M, Nicolai CJ, Bourgeois-Daigneault MC, Trevino TN, Azimi CS, Scheer AK, Randolph HE, Thompson TW, Zhang L, Iannello A, Mathur N, Jardine KE, Kirn GA, Bell JC, McBurney MW, Raulet DH, Ardolino M. J Clin Invest. 2018 Oct 1;128(10):4654-4668. doi: 10.1172/JCI99317. Epub 2018 Sep 10. PubMed |
| miR-191 modulates B-cell development and targets transcription factors E2A, Foxp1, and Egr1. Blume J, Zietara N, Witzlau K, Liu Y, Sanchez OO, Puchalka J, Winter SJ, Kunze-Schumacher H, Saran N, Duber S, Roy B, Weiss S, Klein C, Wurst W, Lyszkiewicz M, Krueger A. Eur J Immunol. 2019 Jan;49(1):121-132. doi: 10.1002/eji.201847660. Epub 2018 Oct 22. PubMed |
| Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism. Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. PubMed |
| Eomesodermin driven IL-10 production in effector CD8(+) T cells promotes a memory phenotype. Reiser J, Sadashivaiah K, Furusawa A, Banerjee A, Singh N. Cell Immunol. 2019 Jan;335:93-102. doi: 10.1016/j.cellimm.2018.11.008. Epub 2018 Dec 1. PubMed |
| Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR. Zhu H, Bhatt B, Sivaprakasam S, Cai Y, Liu S, Kodeboyina SK, Patel N, Savage NM, Sharma A, Kaufman RJ, Li H, Singh N. Nat Commun. 2019 Mar 6;10(1):1084. doi: 10.1038/s41467-019-08908-5. PubMed |
| The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, Ware CF, Kronenberg M, Dustin ML, Cyster JG. Immunity. 2019 Aug 20;51(2):310-323.e7. doi: 10.1016/j.immuni.2019.05.022. Epub 2019 Jun 13. PubMed |
Genetic modification of primary human B cells to model high-grade lymphoma.
Caeser R, Di Re M, Krupka JA, Gao J, Lara-Chica M, Dias JML, Cooke SL, Fenner R, Usheva Z, Runge HFP, Beer PA, Eldaly H, Pak HK, Park CS, Vassiliou GS, Huntly BJP, Mupo A, Bashford-Rogers RJM, Hodson DJ.
Nat Commun. 2019 Oct 4;10(1):4543. doi: 10.1038/s41467-019-12494-x.
PubMed
Associated Plasmids |
| Cathelicidin-Related Antimicrobial Peptide Regulates CD73 Expression in Mouse Th17 Cells via p38. Lee J, Shin KO, Kim Y, Cho J, Lim HW, Yoon SI, Lee GS, Ko HJ, Kim PH, Uchida Y, Park K, Kang SG. Cells. 2020 Jun 26;9(6). pii: cells9061561. doi: 10.3390/cells9061561. PubMed |
| GSK3 Restrains Germinal Center B Cells to Form Plasma Cells. Lee J, Park H, Lim J, Jin HS, Park Y, Jung YJ, Ko HJ, Yoon SI, Lee GS, Kim PH, Choi SS, Xiao C, Kang SG. J Immunol. 2021 Feb 1;206(3):481-493. doi: 10.4049/jimmunol.2000908. Epub 2020 Dec 21. PubMed |
| The TGF-beta superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation. Wu B, Zhang S, Guo Z, Bi Y, Zhou M, Li P, Seyedsadr M, Xu X, Li JL, Markovic-Plese S, Wan YY. Immunity. 2021 Feb 9;54(2):308-323.e6. doi: 10.1016/j.immuni.2020.12.010. Epub 2021 Jan 8. PubMed |
| Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell MB, Cui W. Cancer Immunol Res. 2021 Apr;9(4):454-469. doi: 10.1158/2326-6066.CIR-20-0433. Epub 2021 Feb 12. PubMed |
| Neoantigens as potential vaccines in hepatocellular carcinoma. Reparaz D, Ruiz M, Llopiz D, Silva L, Vercher E, Aparicio B, Egea J, Tamayo-Uria I, Hervas-Stubbs S, Garcia-Balduz J, Castro C, Inarrairaegui M, Tagliamonte M, Mauriello A, Cavalluzzo B, Buonaguro L, Rohrer C, Heim K, Tauber C, Hofmann M, Thimme R, Sangro B, Sarobe P. J Immunother Cancer. 2022 Feb;10(2). pii: jitc-2021-003978. doi: 10.1136/jitc-2021-003978. PubMed |
| RORgammat phosphorylation protects against T cell-mediated inflammation. Ma S, Patel SA, Abe Y, Chen N, Patel PR, Cho BS, Abbasi N, Zeng S, Schnabl B, Chang JT, Huang WJM. Cell Rep. 2022 Mar 15;38(11):110520. doi: 10.1016/j.celrep.2022.110520. PubMed |
| When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer. Hasim MS, Marotel M, Hodgins JJ, Vulpis E, Makinson OJ, Asif S, Shih HY, Scheer AK, MacMillan O, Alonso FG, Burke KP, Cook DP, Li R, Petrucci MT, Santoni A, Fallon PG, Sharpe AH, Sciume G, Veillette A, Zingoni A, Gray DA, McCurdy A, Ardolino M. Sci Adv. 2022 Apr 15;8(15):eabj3286. doi: 10.1126/sciadv.abj3286. Epub 2022 Apr 13. PubMed |
| T Cell-Mediated Targeted Delivery of Anti-PD-L1 Nanobody Overcomes Poor Antibody Penetration and Improves PD-L1 Blocking at the Tumor Site. Petit PF, Bombart R, Desimpel PH, Naulaerts S, Thouvenel L, Collet JF, Van den Eynde BJ, Zhu J. Cancer Immunol Res. 2022 Jun 3;10(6):713-727. doi: 10.1158/2326-6066.CIR-21-0801. PubMed |
| Inhibition of acylglycerol kinase sensitizes DLBCL to venetoclax via upregulation of FOXO1-mediated BCL-2 expression. Ning N, Zhang S, Wu Q, Li X, Kuang D, Duan Y, Xia M, Liu H, Weng J, Ba H, Tang Z, Cheng X, Mei H, Huang L, Ao Q, Wang G, Hu Y, Laurence A, Wang J, Wang G, Yang XP. Theranostics. 2022 Jul 18;12(12):5537-5550. doi: 10.7150/thno.72786. eCollection 2022. PubMed |
| Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy. Bittner S, Ruhland B, Hofmann V, Schmidleithner L, Schambeck K, Pant A, Stuve P, Delacher M, Echtenacher B, Edinger M, Hoffmann P, Rehli M, Gebhard C, Strieder N, Hehlgans T, Feuerer M. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2208436119. doi: 10.1073/pnas.2208436119. Epub 2022 Sep 26. PubMed |
| Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape. Mangolini M, Maiques-Diaz A, Charalampopoulou S, Gerhard-Hartmann E, Bloehdorn J, Moore A, Giachetti G, Lu J, Roamio Franklin VN, Chilamakuri CSR, Moutsopoulos I, Rosenwald A, Stilgenbauer S, Zenz T, Mohorianu I, D'Santos C, Deaglio S, Hodson DJ, Martin-Subero JI, Ringshausen I. Nat Commun. 2022 Oct 20;13(1):6220. doi: 10.1038/s41467-022-33739-2. PubMed |
| Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer. Aparicio B, Reparaz D, Ruiz M, Llopiz D, Silva L, Vercher E, Theunissen P, Tamayo I, Smerdou C, Igea A, Santisteban M, Gonzalez-Deza C, Lasarte JJ, Hervas-Stubbs S, Sarobe P. Front Immunol. 2022 Nov 2;13:985886. doi: 10.3389/fimmu.2022.985886. eCollection 2022. PubMed |
| Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs. Finnigan J, Newman J, Patskovsky Y, Patskovska L, Ishizuka A, Lynn G, Seder R, Krogsgaard M, Bhardwaj N. Res Sq. 2023 Jan 31:rs.3.rs-2531184. doi: 10.21203/rs.3.rs-2531184/v1. Preprint. PubMed |
| Structural basis for self-discrimination by neoantigen-specific TCRs. Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. PubMed |
| T-bet deficiency and Hic1 induction override TGF-beta-dependency in the formation of CD103(+) intestine-resident memory CD8(+) T cells. Wang L, Mishra S, Fan KK, Quon S, Li G, Yu B, Liao W, Liu Y, Zhang X, Qiu Y, Li Y, Goldrath AW, Ma C, Zhang N. Cell Rep. 2024 Jun 25;43(6):114258. doi: 10.1016/j.celrep.2024.114258. Epub 2024 May 22. PubMed |
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