pCI-neo Flag HAUSP Citations (17)

Originally described in: HAUSP is required for p53 destabilization.
Cummins JM, Vogelstein B Cell Cycle. 2004 Jun . 3(6):689-92. PubMed Journal

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Articles Citing pCI-neo Flag HAUSP

Articles
USP10 regulates p53 localization and stability by deubiquitinating p53. Yuan J, Luo K, Zhang L, Cheville JC, Lou Z. Cell. 2010 Feb 5;140(3):384-96. doi: 10.1016/j.cell.2009.12.032. Epub 2010 Jan 21. PubMed
USP7/HAUSP stimulates repair of oxidative DNA lesions. Khoronenkova SV, Dianova II, Parsons JL, Dianov GL. Nucleic Acids Res. 2011 Apr;39(7):2604-9. doi: 10.1093/nar/gkq1210. Epub 2010 Dec 7. PubMed
USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Hall JA, Tabata M, Rodgers JT, Puigserver P. Mol Endocrinol. 2014 Jun;28(6):912-24. doi: 10.1210/me.2013-1420. Epub 2014 Apr 2. PubMed
HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator. Bhattacharya S, Ghosh MK. FEBS J. 2014 Jul;281(13):3061-78. doi: 10.1111/febs.12843. Epub 2014 Jun 10. PubMed
The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7. Zemp I, Lingner J. J Biol Chem. 2014 Oct 10;289(41):28595-606. doi: 10.1074/jbc.M114.596056. Epub 2014 Aug 29. PubMed
DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. Papp SJ, Huber AL, Jordan SD, Kriebs A, Nguyen M, Moresco JJ, Yates JR, Lamia KA. Elife. 2015 Mar 10;4. doi: 10.7554/eLife.04883. PubMed
USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation. Mungamuri SK, Qiao RF, Yao S, Manfredi JJ, Gu W, Aaronson SA. Cell Rep. 2016 Mar 22;14(11):2528-37. doi: 10.1016/j.celrep.2016.02.049. Epub 2016 Mar 10. PubMed
Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Lamberto I, Liu X, Seo HS, Schauer NJ, Iacob RE, Hu W, Das D, Mikhailova T, Weisberg EL, Engen JR, Anderson KC, Chauhan D, Dhe-Paganon S, Buhrlage SJ. Cell Chem Biol. 2017 Dec 21;24(12):1490-1500.e11. doi: 10.1016/j.chembiol.2017.09.003. Epub 2017 Oct 19. PubMed
BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage. Biswas K, Philip S, Yadav A, Martin BK, Burkett S, Singh V, Babbar A, North SL, Chang S, Sharan SK. Nat Commun. 2018 Feb 7;9(1):537. doi: 10.1038/s41467-018-03020-6. PubMed
Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms. Wang X, Zhang Q, Wang Y, Zhuang H, Chen B. Med Sci Monit. 2018 Mar 25;24:1742-1750. PubMed
Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma. Franqui-Machin R, Hao M, Bai H, Gu Z, Zhan X, Habelhah H, Jethava Y, Qiu L, Frech I, Tricot G, Zhan F. J Clin Invest. 2018 Jul 2;128(7):2877-2893. doi: 10.1172/JCI98765. Epub 2018 Jun 4. PubMed
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. Nat Commun. 2020 May 8;11(1):2289. doi: 10.1038/s41467-020-16038-6. PubMed
USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway. Zhang T, Periz G, Lu YN, Wang J. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28114-28125. doi: 10.1073/pnas.2014349117. Epub 2020 Oct 26. PubMed
TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies. Li C, Xia J, Franqui-Machin R, Chen F, He Y, Ashby TC, Teng F, Xu H, Liu D, Gai D, Johnson SK, van Rhee F, Janz S, Shaughnessy JD Jr, Tricot G, Frech I, Zhan F. J Clin Invest. 2021 Jul 15;131(14). pii: e146893. doi: 10.1172/JCI146893. PubMed
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation. Sun Y, Chen J, Huang SN, Su YP, Wang W, Agama K, Saha S, Jenkins LM, Pascal JM, Pommier Y. Nat Commun. 2021 Aug 18;12(1):5010. doi: 10.1038/s41467-021-25252-9. PubMed
Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7. Frey Y, Franz-Wachtel M, Macek B, Olayioye MA. Sci Rep. 2022 Mar 23;12(1):5036. doi: 10.1038/s41598-022-08844-3. PubMed
Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice. Qiao H, Tian Y, Huo Y, Man HY. iScience. 2022 Jun 14;25(7):104595. doi: 10.1016/j.isci.2022.104595. eCollection 2022 Jul 15. PubMed

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