pSin-EF2-Oct4-Pur Citations (33)
Originally described in: Induced pluripotent stem cell lines derived from human somatic cells.Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, Thomson JA Science. 2007 Dec 21. 318(5858):1917-20. PubMed Journal
Articles Citing pSin-EF2-Oct4-Pur
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| Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Yakubov E, Rechavi G, Rozenblatt S, Givol D. Biochem Biophys Res Commun. 2010 Mar 26. 394(1):189-93. PubMed |
| Engineering of human pluripotent stem cells by AAV-mediated gene targeting. Khan IF, Hirata RK, Wang PR, Li Y, Kho J, Nelson A, Huo Y, Zavaljevski M, Ware C, Russell DW. Mol Ther. 2010 Jun;18(6):1192-9. doi: 10.1038/mt.2010.55. Epub 2010 Apr 20. PubMed |
| Human induced pluripotent stem cells derived from fetal neural stem cells successfully undergo directed differentiation into cartilage. Medvedev SP, Grigor'eva EV, Shevchenko AI, Malakhova AA, Dementyeva EV, Shilov AA, Pokushalov EA, Zaidman AM, Aleksandrova MA, Plotnikov EY, Sukhikh GT, Zakian SM. Stem Cells Dev. 2011 Jun;20(6):1099-112. doi: 10.1089/scd.2010.0249. Epub 2010 Oct 17. PubMed |
| Effects of estrogen on the proportion of stem cells in the breast. Simoes BM, Piva M, Iriondo O, Comaills V, Lopez-Ruiz JA, Zabalza I, Mieza JA, Acinas O, Vivanco MD. Breast Cancer Res Treat. 2011 Aug;129(1):23-35. doi: 10.1007/s10549-010-1169-4. Epub 2010 Sep 22. PubMed |
| Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology. Ruan J, Shen J, Wang Z, Ji J, Song H, Wang K, Liu B, Li J, Cui D. Int J Nanomedicine. 2011;6:425-35. doi: 10.2147/IJN.S16498. Epub 2011 Feb 21. PubMed |
| Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed |
| Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs. Deyle DR, Khan IF, Ren G, Wang PR, Kho J, Schwarze U, Russell DW. Mol Ther. 2012 Jan;20(1):204-13. doi: 10.1038/mt.2011.209. Epub 2011 Oct 25. PubMed |
| Developmental incompatibility of human parthenogenetic embryonic stem cells in mouse blastocysts. Du L, Xu X, Duan X, Lu G, Lin G. In Vitro Cell Dev Biol Anim. 2012 Mar;48(3):156-64. doi: 10.1007/s11626-012-9483-2. Epub 2012 Jan 20. PubMed |
| Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA, Guerra M, Guo W, Xu X. Oncogene. 2012 Nov 22;31(47):4898-911. doi: 10.1038/onc.2011.656. Epub 2012 Jan 30. PubMed |
| Sumoylation of Kruppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation. Tahmasebi S, Ghorbani M, Savage P, Yan K, Gocevski G, Xiao L, You L, Yang XJ. J Biol Chem. 2013 May 3;288(18):12791-804. doi: 10.1074/jbc.M113.465443. Epub 2013 Mar 20. PubMed |
| CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia. Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G, Priori SG. Cell Death Dis. 2013 Oct 10;4:e843. doi: 10.1038/cddis.2013.369. PubMed |
| Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium. Zhang L, Pan Y, Qin G, Chen L, Chatterjee TK, Weintraub NL, Tang Y. Cell Cycle. 2014;13(5):762-71. doi: 10.4161/cc.27677. Epub 2014 Jan 6. PubMed |
| Activation of neural cell fate programs toward direct conversion of adult human fibroblasts into tri-potent neural progenitors using OCT-4. Mitchell RR, Szabo E, Benoit YD, Case DT, Mechael R, Alamilla J, Lee JH, Fiebig-Comyn A, Gillespie DC, Bhatia M. Stem Cells Dev. 2014 Aug 15;23(16):1937-46. doi: 10.1089/scd.2014.0023. Epub 2014 May 13. PubMed |
| The SUMO conjugating enzyme Ubc9 is required for inducing and maintaining stem cell pluripotency. Tahmasebi S, Ghorbani M, Savage P, Gocevski G, Yang XJ. Stem Cells. 2014 Apr;32(4):1012-20. doi: 10.1002/stem.1600. PubMed |
| Differentiation of primordial germ cells from induced pluripotent stem cells of primary ovarian insufficiency. Leng L, Tan Y, Gong F, Hu L, Ouyang Q, Zhao Y, Lu G, Lin G. Hum Reprod. 2015 Mar;30(3):737-48. doi: 10.1093/humrep/deu358. Epub 2015 Jan 12. PubMed |
| Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion. Zhu S, Wang H, Ding S. Nat Protoc. 2015 Jul;10(7):959-73. doi: 10.1038/nprot.2015.059. Epub 2015 Jun 4. PubMed |
| Prothymosin-alpha Overexpression Contributes to the Development of Insulin Resistance. Su YC, Ou HY, Wu HT, Wu P, Chen YC, Su BH, Shiau AL, Chang CJ, Wu CL. J Clin Endocrinol Metab. 2015 Nov;100(11):4114-23. doi: 10.1210/jc.2015-2277. Epub 2015 Sep 8. PubMed |
| Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming. Liu Z, Skamagki M, Kim K, Zhao R. Stem Cell Reports. 2015 Dec 8;5(6):1119-27. doi: 10.1016/j.stemcr.2015.11.002. PubMed |
| Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer. Lu CS, Shieh GS, Wang CT, Su BH, Su YC, Chen YC, Su WC, Wu P, Yang WH, Shiau AL, Wu CL. Oncotarget. 2016 May 26. doi: 10.18632/oncotarget.9602. PubMed |
| Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells. Chang WF, Hwu YM, Xu J, Lin CJ, Wang SW, Cheng AS, Lu J, Lu CH, Sung LY. PLoS One. 2016 Nov 1;11(11):e0165715. doi: 10.1371/journal.pone.0165715. eCollection 2016. PubMed |
| Generation of induced pluripotent stem cells (iPSCs) from a retinoblastoma patient carrying a c.2663G>A mutation in RB1 gene. Zeng S, Liu L, Ouyang Q, Zhao Y, Lin G, Hu L, Li W. Stem Cell Res. 2016 Sep;17(2):208-211. doi: 10.1016/j.scr.2016.08.015. Epub 2016 Aug 28. PubMed |
| Tocopherols inhibit estrogen-induced cancer stemness and OCT4 signaling in breast cancer. Bak MJ, Furmanski P, Shan NL, Lee HJ, Bao C, Lin Y, Shih WJ, Yang CS, Suh N. Carcinogenesis. 2018 May 26. pii: 5004853. doi: 10.1093/carcin/bgy071. PubMed |
| Transcription factor induced conversion of human fibroblasts towards the hair cell lineage. Duran Alonso MB, Lopez Hernandez I, de la Fuente MA, Garcia-Sancho J, Giraldez F, Schimmang T. PLoS One. 2018 Jul 6;13(7):e0200210. doi: 10.1371/journal.pone.0200210. eCollection 2018. PubMed |
| Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, Zsiros E, Wang K, Yang X, Kurita T, Xu EY. Cell Rep. 2019 Feb 26;26(9):2434-2450.e6. doi: 10.1016/j.celrep.2019.01.111. PubMed |
Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts.
Peskova L, Cerna K, Oppelt J, Mraz M, Barta T.
Sci Rep. 2019 Oct 31;9(1):15759. doi: 10.1038/s41598-019-52294-3.
PubMed
Associated Plasmids |
| Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line. Ruiz G, Valencia-Gonzalez HA, Perez-Montiel D, Munoz F, Ocadiz-Delgado R, Fernandez-Retana J, Perez-Plasencia C, Resendis-Antonio O, Gariglio P, Garcia-Carranca A. Stem Cells Int. 2019 Dec 1;2019:7683817. doi: 10.1155/2019/7683817. eCollection 2019. PubMed |
| The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis. Endo M, Druso JE, Cerione RA. J Biol Chem. 2020 Apr 3;295(14):4498-4512. doi: 10.1074/jbc.RA119.011837. Epub 2020 Feb 18. PubMed |
| Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer. Lu CS, Shiau AL, Su BH, Hsu TS, Wang CT, Su YC, Tsai MS, Feng YH, Tseng YL, Yen YT, Wu CL, Shieh GS. J Hematol Oncol. 2020 Jun 1;13(1):62. doi: 10.1186/s13045-020-00887-1. PubMed |
| High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Generali M, Satheesha S, Bode PK, Wanner D, Schafer BW, Casanova EA. Genes (Basel). 2021 Aug 31;12(9). pii: genes12091373. doi: 10.3390/genes12091373. PubMed |
| A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer. Morgan MAJ, Popova IK, Vaidya A, Burg JM, Marunde MR, Rendleman EJ, Dumar ZJ, Watson R, Meiners MJ, Howard SA, Khalatyan N, Vaughan RM, Rothbart SB, Keogh MC, Shilatifard A. Genes Dev. 2021 Dec 1;35(23-24):1642-1656. doi: 10.1101/gad.348766.121. Epub 2021 Nov 24. PubMed |
| LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c. Deshpande RP, Sharma S, Liu Y, Pandey PR, Pei X, Wu K, Wu SY, Tyagi A, Zhao D, Mo YY, Watabe K. Breast Cancer Res. 2022 Jan 25;24(1):6. doi: 10.1186/s13058-022-01504-4. PubMed |
| Inhibiting ALK2/ALK3 Signaling to Differentiate and Chemo-Sensitize Medulloblastoma. Filipponi D, Pagnuzzi-Boncompagni M, Pages G. Cancers (Basel). 2022 Apr 22;14(9). pii: cancers14092095. doi: 10.3390/cancers14092095. PubMed |
| Phase transition and remodeling complex assembly are important for SS18-SSX oncogenic activity in synovial sarcomas. Cheng Y, Shen Z, Gao Y, Chen F, Xu H, Mo Q, Chu X, Peng CL, McKenzie TT, Palacios BE, Hu J, Zhou H, Long J. Nat Commun. 2022 May 18;13(1):2724. doi: 10.1038/s41467-022-30447-9. PubMed |
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