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pGL3-OT (wt TCF-4 sites) Citations (17)

Originally described in: The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.
Shih IM, Yu J, He TC, Vogelstein B, Kinzler KW Cancer Res. 2000 Mar 15. 60(6):1671-6.
PubMed

Articles Citing pGL3-OT (wt TCF-4 sites)

Articles
Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Kleeff J, Maruyama H, Friess H, Buchler MW, Falb D, Korc M. Biochem Biophys Res Commun. 1999 Feb 16;255(2):268-73. PubMed
The beta-catenin/TCF complex as a novel target of resveratrol in the Wnt/beta-catenin signaling pathway. Chen HJ, Hsu LS, Shia YT, Lin MW, Lin CM. Biochem Pharmacol. 2012 Nov 1;84(9):1143-53. doi: 10.1016/j.bcp.2012.08.011. Epub 2012 Aug 19. PubMed
miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma. Shen G, Jia H, Tai Q, Li Y, Chen D. Carcinogenesis. 2013 Jan;34(1):211-9. doi: 10.1093/carcin/bgs320. Epub 2012 Oct 20. PubMed
Biological activity of oleanane triterpene derivatives obtained by chemical derivatization. Cheng SY, Wang CM, Cheng HL, Chen HJ, Hsu YM, Lin YC, Chou CH. Molecules. 2013 Oct 18;18(10):13003-19. doi: 10.3390/molecules181013003. PubMed
Smad6 suppresses the growth and self-renewal of hepatic progenitor cells. Ding ZY, Liang HF, Jin GN, Chen WX, Wang W, Datta PK, Zhang MZ, Zhang B, Chen XP. J Cell Physiol. 2014 May;229(5):651-60. doi: 10.1002/jcp.24488. PubMed
Glucocorticoid Receptor beta Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation. Wang Q, Lu PH, Shi ZF, Xu YJ, Xiang J, Wang YX, Deng LX, Xie P, Yin Y, Zhang B, Mu HJ, Qiao WZ, Cui H, Zou J. Mol Neurobiol. 2014 Oct 10. PubMed
miR-532 promoted gastric cancer migration and invasion by targeting NKD1. Hu S, Zheng Q, Wu H, Wang C, Liu T, Zhou W. Life Sci. 2017 May 15;177:15-19. doi: 10.1016/j.lfs.2017.03.019. Epub 2017 Mar 27. PubMed
Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/beta-catenin signaling pathways in human colon cancer cells. Hseu YC, Chao YH, Lin KY, Way TD, Lin HY, Thiyagarajan V, Yang HL. J Ethnopharmacol. 2017 Jul 5;208:72-83. doi: 10.1016/j.jep.2017.07.001. PubMed
Depletion of MUC5B mucin in gastrointestinal cancer cells alters their tumorigenic properties: implication of the Wnt/beta-catenin pathway. Lahdaoui F, Messager M, Vincent A, Hec F, Gandon A, Warlaumont M, Renaud F, Leteurtre E, Piessen G, Jonckheere N, Mariette C, Van Seuningen I. Biochem J. 2017 Nov 1;474(22):3733-3746. doi: 10.1042/BCJ20170348. PubMed
DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/beta-catenin pathway. Zhang T, Ma Z, Liu L, Sun J, Tang H, Zhang B, Zou Y, Li H. Cell Death Dis. 2018 Jun 4;9(6):675. doi: 10.1038/s41419-018-0591-0. PubMed
CHAF1A interacts with TCF4 to promote gastric carcinogenesis via upregulation of c-MYC and CCND1 expression. Zheng L, Liang X, Li S, Li T, Shang W, Ma L, Jia X, Shao W, Sun P, Chen C, Jia J. EBioMedicine. 2018 Dec;38:69-78. doi: 10.1016/j.ebiom.2018.11.009. Epub 2018 Nov 16. PubMed
Antrodia salmonea suppresses invasion and metastasis in triple-negative breast cancer cells by reversing EMT through the NF-kappaB and Wnt/beta-catenin signaling pathway. Hseu YC, Lin YC, Rajendran P, Thigarajan V, Mathew DC, Lin KY, Way TD, Liao JW, Yang HL. Food Chem Toxicol. 2019 Feb;124:219-230. doi: 10.1016/j.fct.2018.12.009. Epub 2018 Dec 7. PubMed
Platelet-rich fibrin increases the osteoprotegerin/receptor activator of nuclear factor-kappaB ligand ratio in osteoblasts. Sumida R, Maeda T, Kawahara I, Yusa J, Kato Y. Exp Ther Med. 2019 Jul;18(1):358-365. doi: 10.3892/etm.2019.7560. Epub 2019 May 8. PubMed
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/beta-Catenin Signaling. Ping MH. Cancer Manag Res. 2020 Nov 17;12:11773-11782. doi: 10.2147/CMAR.S270544. eCollection 2020. PubMed
FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway. He S, Wang W, Wan Z, Shen H, Zhao Y, You Z, Liu J, Zhu L. Oncogenesis. 2021 Jan 9;10(1):6. doi: 10.1038/s41389-020-00301-y. PubMed
Exosome-derived microRNA-433 inhibits tumorigenesis through incremental infiltration of CD4 and CD8 cells in non-small cell lung cancer. Liu B, Zhang R, Zhu Y, Hao R. Oncol Lett. 2021 Aug;22(2):607. doi: 10.3892/ol.2021.12868. Epub 2021 Jun 15. PubMed
MAP3K1 regulates female reproductive tract development. Kimura E, Mongan M, Xiao B, Christianto A, Wang J, Carreira VS, Bolon B, Zhang X, Burns KA, Biesiada J, Medvedovic M, Puga A, Xia Y. Dis Model Mech. 2024 Mar 1;17(3):dmm050669. doi: 10.1242/dmm.050669. Epub 2024 Mar 28. PubMed

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