pCMV-Neo-Bam p53 wt Citations (36)

Originally described in: Suppression of human colorectal carcinoma cell growth by wild-type p53.
Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B Science. 1990 Aug 24. 249(4971):912-5. PubMed Journal

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Articles Citing pCMV-Neo-Bam p53 wt

Articles
Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells. Sauer L, Gitenay D, Vo C, Baron VT. Oncogene. 2010 May 6;29(18):2628-37. doi: 10.1038/onc.2010.24. Epub 2010 Mar 1. PubMed
Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53. Saleh AD, Savage JE, Cao L, Soule BP, Ly D, DeGraff W, Harris CC, Mitchell JB, Simone NL. PLoS One. 2011;6(10):e24429. doi: 10.1371/journal.pone.0024429. Epub 2011 Oct 11. PubMed
p53 and microRNA-34 are suppressors of canonical Wnt signaling. Kim NH, Kim HS, Kim NG, Lee I, Choi HS, Li XY, Kang SE, Cha SY, Ryu JK, Na JM, Park C, Kim K, Lee S, Gumbiner BM, Yook JI, Weiss SJ. Sci Signal. 2011 Nov 1;4(197):ra71. doi: 10.1126/scisignal.2001744. PubMed
Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation. Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Physiol Genomics. 2012 Jun 15;44(12):638-50. doi: 10.1152/physiolgenomics.00028.2012. Epub 2012 May 1. PubMed
High-mobility group box 2 (HMGB2) modulates radioresponse and is downregulated by p53 in colorectal cancer cell. Shin YJ, Kim MS, Kim MS, Lee J, Kang M, Jeong JH. Cancer Biol Ther. 2013 Mar;14(3):213-21. doi: 10.4161/cbt.23292. Epub 2012 Dec 19. PubMed
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. Ferreira DM, Afonso MB, Rodrigues PM, Simao AL, Pereira DM, Borralho PM, Rodrigues CM, Castro RE. Mol Cell Biol. 2014 Mar;34(6):1100-20. doi: 10.1128/MCB.00420-13. Epub 2014 Jan 13. PubMed
Mutation or loss of p53 differentially modifies TGFbeta action in ovarian cancer. O hAinmhire E, Quartuccio SM, Cheng W, Ahmed RA, King SM, Burdette JE. PLoS One. 2014 Feb 20;9(2):e89553. doi: 10.1371/journal.pone.0089553. eCollection 2014. PubMed
A PTCH1 homolog transcriptionally activated by p53 suppresses Hedgehog signaling. Chung JH, Larsen AR, Chen E, Bunz F. J Biol Chem. 2014 Nov 21;289(47):33020-31. doi: 10.1074/jbc.M114.597203. Epub 2014 Oct 8. PubMed
Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin. Escobar D, Hepp MI, Farkas C, Campos T, Sodir NM, Morales M, Alvarez CI, Swigart L, Evan GI, Gutierrez JL, Nishinakamura R, Castro AF, Pincheira R. Cell Death Dis. 2015 Jul 16;6:e1816. doi: 10.1038/cddis.2015.165. PubMed
Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Ho DH, Kim H, Kim J, Sim H, Ahn H, Kim J, Seo H, Chung KC, Park BJ, Son I, Seol W. Mol Brain. 2015 Sep 18;8:54. doi: 10.1186/s13041-015-0145-7. PubMed
Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes. Salari A, Thomay K, Himmler K, Vajen B, Schienke A, Hagedorn M, Ebersold J, Kreipe HH, Kruger A, Schambach A, Schlegelberger B, Gohring G. Cancer Genet. 2016 Jun;209(6):258-66. doi: 10.1016/j.cancergen.2016.04.004. Epub 2016 Apr 22. PubMed
FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors. Kitade S, Onoyama I, Kobayashi H, Yagi H, Yoshida S, Kato M, Tsunematsu R, Asanoma K, Sonoda K, Wake N, Hata K, Nakayama KI, Kato K. Cancer Sci. 2016 Oct;107(10):1399-1405. doi: 10.1111/cas.13026. Epub 2016 Sep 24. PubMed
Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Karthikeyan S, Lantvit DD, Chae DH, Burdette JE. Oncotarget. 2016 Oct 25;7(43):69871-69882. doi: 10.18632/oncotarget.11499. PubMed
6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells. Ros S, Floter J, Kaymak I, Da Costa C, Houddane A, Dubuis S, Griffiths B, Mitter R, Walz S, Blake S, Behrens A, Brindle KM, Zamboni N, Rider MH, Schulze A. Oncogene. 2017 Jun 8;36(23):3287-3299. doi: 10.1038/onc.2016.477. Epub 2017 Jan 16. PubMed
The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress in osteosarcoma cells. Mukherjee S, Dash S, Lohitesh K, Chowdhury R. PLoS One. 2017 Jun 9;12(6):e0179203. doi: 10.1371/journal.pone.0179203. eCollection 2017. PubMed
Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Ho DH, Kim H, Kim J, Sim H, Ahn H, Kim J, Seo H, Chung KC, Park BJ, Son I, Seol W. Mol Brain. 2017 Oct 6;10(1):48. doi: 10.1186/s13041-017-0327-6. PubMed
Development of a genetic sensor that eliminates p53 deficient cells. Mircetic J, Dietrich A, Paszkowski-Rogacz M, Krause M, Buchholz F. Nat Commun. 2017 Nov 13;8(1):1463. doi: 10.1038/s41467-017-01688-w. PubMed
Effect of TP53 contact and conformational mutations on cell survival and erythropoiesis of human hematopoietic stem cells in a long term culture model. Salari A, Thomay K, Lentes J, Ebersold J, Hagedorn M, Skawran B, Davenport C, Schambach A, Schlegelberger B, Gohring G. Oncotarget. 2018 Jul 6;9(52):29869-29876. doi: 10.18632/oncotarget.25581. eCollection 2018 Jul 6. PubMed
p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT. Yang-Hartwich Y, Tedja R, Roberts CM, Goodner-Bingham J, Cardenas C, Gurea M, Sumi NJ, Alvero AB, Glackin CA, Mor G. Mol Cancer Res. 2019 Jan;17(1):153-164. doi: 10.1158/1541-7786.MCR-18-0238. Epub 2018 Aug 21. PubMed
Role of p53 and transcription-independent p53-induced apoptosis in shear-stimulated megakaryocytic maturation, particle generation, and platelet biogenesis. Luff SA, Kao CY, Papoutsakis ET. PLoS One. 2018 Sep 19;13(9):e0203991. doi: 10.1371/journal.pone.0203991. eCollection 2018. PubMed
Expression of Micro-RNA-492 (MiR-492) in Human Cervical Cancer Cell Lines is Upregulated by Transfection with Wild-Type P53, Irradiation, and 5-Fluorouracil Treatment In Vitro. Liu M, Wang Z, Liu Q, Zhu H, Xu N. Med Sci Monit. 2018 Oct 30;24:7750-7758. doi: 10.12659/MSM.911585. PubMed
Autophagy Regulated by Gain of Function Mutant p53 Enhances Proteasomal Inhibitor-Mediated Cell Death through Induction of ROS and ERK in Lung Cancer Cells. Saini H, Hakeem I, Mukherjee S, Chowdhury S, Chowdhury R. J Oncol. 2019 Jan 6;2019:6164807. doi: 10.1155/2019/6164807. eCollection 2019. PubMed
Transfection with p21 and p53 tumor suppressor plasmids suppressed breast tumor growth in syngeneic mouse model. Ibnat N, Kamaruzman NI, Ashaie M, Chowdhury EH. Gene. 2019 Jun 15;701:32-40. doi: 10.1016/j.gene.2019.02.082. Epub 2019 Mar 18. PubMed
Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer. Shin YJ, Kim Y, Wen X, Cho NY, Lee S, Kim WH, Kang GH. Clin Epigenetics. 2019 May 14;11(1):77. doi: 10.1186/s13148-019-0661-x. PubMed
p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition. Aggarwal M, Saxena R, Asif N, Sinclair E, Tan J, Cruz I, Berry D, Kallakury B, Pham Q, Wang TTY, Chung FL. J Exp Clin Cancer Res. 2019 Jul 15;38(1):307. doi: 10.1186/s13046-019-1267-z. PubMed
Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response. Lin S, Yu L, Song X, Bi J, Jiang L, Wang Y, He M, Xiao Q, Sun M, Olopade OI, Zhao L, Wei M. Cell Death Dis. 2019 Sep 11;10(9):666. doi: 10.1038/s41419-019-1871-z. PubMed
Mutated p53 Promotes the Symmetric Self-Renewal of Cisplatin-Resistant Lung Cancer Stem-Like Cells and Inhibits the Recruitment of Macrophages. Xu Y, Xu Z, Li Q, Guo L, Wang Y, Zhou J, Wang G, Liu Y. J Immunol Res. 2019 Oct 31;2019:7478538. doi: 10.1155/2019/7478538. eCollection 2019. PubMed
Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia. Mancikova V, Peschelova H, Kozlova V, Ledererova A, Ladungova A, Verner J, Loja T, Folber F, Mayer J, Pospisilova S, Smida M. J Immunother Cancer. 2020 Mar;8(1). pii: jitc-2019-000471. doi: 10.1136/jitc-2019-000471. PubMed
Interaction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M. Lim J, Choi JH, Park EM, Choi YH. Korean J Physiol Pharmacol. 2020 May 1;24(3):203-212. doi: 10.4196/kjpp.2020.24.3.203. PubMed
Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1. Long J, Galvan DL, Mise K, Kanwar YS, Li L, Poungvarin N, Overbeek PA, Chang BH, Danesh FR. J Biol Chem. 2020 May 28. pii: RA120.013228. doi: 10.1074/jbc.RA120.013228. PubMed
Murine Cytomegalovirus M25 Proteins Sequester the Tumor Suppressor Protein p53 in Nuclear Accumulations. Kutle I, Szymanska-de Wijs KM, Bogdanow B, Cuvalo B, Steinbruck L, Jonjic S, Wagner K, Niedenthal R, Selbach M, Wiebusch L, Dezeljin M, Messerle M. J Virol. 2020 Sep 29;94(20):e00574-20. doi: 10.1128/JVI.00574-20. Print 2020 Sep 29. PubMed
Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells. Saini H, Sharma H, Mukherjee S, Chowdhury S, Chowdhury R. Cancer Cell Int. 2021 Jan 14;21(1):52. doi: 10.1186/s12935-020-01720-y. PubMed
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y, Ahmed J, Houhou T, Karapetyan S, Falls Z, Samudrala R, Pasricha R, Esposito G, Afzal AJ, Hamilton AD, Kumar S, Magzoub M. Nat Commun. 2021 Jun 25;12(1):3962. doi: 10.1038/s41467-021-23985-1. PubMed
O-GlcNAcylated p53 in the liver modulates hepatic glucose production. Gonzalez-Rellan MJ, Fondevila MF, Fernandez U, Rodriguez A, Varela-Rey M, Veyrat-Durebex C, Seoane S, Bernardo G, Lopitz-Otsoa F, Fernandez-Ramos D, Bilbao J, Iglesias C, Novoa E, Ameneiro C, Senra A, Beiroa D, Cunarro J, Dp Chantada-Vazquez M, Garcia-Vence M, Bravo SB, Da Silva Lima N, Porteiro B, Carneiro C, Vidal A, Tovar S, Muller TD, Ferno J, Guallar D, Fidalgo M, Sabio G, Herzig S, Yang WH, Cho JW, Martinez-Chantar ML, Perez-Fernandez R, Lopez M, Dieguez C, Mato JM, Millet O, Coppari R, Woodhoo A, Fruhbeck G, Nogueiras R. Nat Commun. 2021 Aug 20;12(1):5068. doi: 10.1038/s41467-021-25390-0. PubMed
p53 mutants G245S and R337H associated with the Li-Fraumeni syndrome regulate distinct metabolic pathways. Meneghetti BV, Wilson R, Dias CK, Cadore NA, Klamt F, Zaha A, Ferreira HB, Monteiro KM. Biochimie. 2022 Jul;198:141-154. doi: 10.1016/j.biochi.2022.03.003. Epub 2022 Apr 1. PubMed
Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure. Zhang S, El-Deiry WS. Oncotarget. 2024 May 3;15:275-284. doi: 10.18632/oncotarget.28582. PubMed

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