pcDNA3-cmyc Citations (42)
Originally described in: Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.Ricci MS, Jin Z, Dews M, Yu D, Thomas-Tikhonenko A, Dicker DT, El-Deiry WS Mol Cell Biol. 2004 Oct . 24(19):8541-55. PubMed Journal
Articles Citing pcDNA3-cmyc
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Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB. Mott JL, Kurita S, Cazanave SC, Bronk SF, Werneburg NW, Fernandez-Zapico ME. J Cell Biochem. 2010 Aug 1;110(5):1155-64. doi: 10.1002/jcb.22630. PubMed |
Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons. Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J. J Neurosci. 2011 Apr 6;31(14):5271-85. doi: 10.1523/JNEUROSCI.2387-10.2011. PubMed |
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC. Holien T, Vatsveen TK, Hella H, Rampa C, Brede G, Groseth LA, Rekvig M, Borset M, Standal T, Waage A, Sundan A. Leukemia. 2012 May;26(5):1073-80. doi: 10.1038/leu.2011.263. Epub 2011 Sep 23. PubMed |
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments. Leung CT, Brugge JS. Nature. 2012 Feb 8;482(7385):410-3. doi: 10.1038/nature10826. PubMed |
A statin-regulated microRNA represses human c-Myc expression and function. Takwi AA, Li Y, Becker Buscaglia LE, Zhang J, Choudhury S, Park AK, Liu M, Young KH, Park WY, Martin RC, Li Y. EMBO Mol Med. 2012 Sep;4(9):896-909. doi: 10.1002/emmm.201101045. Epub 2012 Aug 7. PubMed |
Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes. Wu I, Shin SC, Cao Y, Bender IK, Jafari N, Feng G, Lin S, Cidlowski JA, Schleimer RP, Lu NZ. Cell Death Dis. 2013 Jan 10;4:e453. doi: 10.1038/cddis.2012.193. PubMed |
Regulation of the bone-restricted IFITM-like (Bril) gene transcription by Sp and Gli family members and CpG methylation. Kasaai B, Gaumond MH, Moffatt P. J Biol Chem. 2013 May 10;288(19):13278-94. doi: 10.1074/jbc.M113.457010. Epub 2013 Mar 24. PubMed |
Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Chhangani D, Mishra A. Sci Rep. 2013;3:1972. doi: 10.1038/srep01972. PubMed |
Myc inhibition impairs autophagosome formation. Toh PP, Luo S, Menzies FM, Rasko T, Wanker EE, Rubinsztein DC. Hum Mol Genet. 2013 Dec 20;22(25):5237-48. doi: 10.1093/hmg/ddt381. Epub 2013 Aug 9. PubMed |
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, Mishra A. Biochim Biophys Acta. 2014 Sep;1842(9):1472-84. doi: 10.1016/j.bbadis.2014.04.014. Epub 2014 Apr 24. PubMed |
Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Sci Rep. 2014 May 28;4:5077. doi: 10.1038/srep05077. PubMed |
The role of miR-200a in mammalian epithelial cell transformation. Becker LE, Takwi AA, Lu Z, Li Y. Carcinogenesis. 2015 Jan;36(1):2-12. doi: 10.1093/carcin/bgu202. Epub 2014 Sep 19. PubMed |
MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer. Shajahan-Haq AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri AM, Facey CO, Hilakivi-Clarke LA, Clarke R. Mol Cancer. 2014 Oct 23;13:239. doi: 10.1186/1476-4598-13-239. PubMed |
c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias. Muvarak N, Kelley S, Robert C, Baer MR, Perrotti D, Gambacorti-Passerini C, Civin C, Scheibner K, Rassool FV. Mol Cancer Res. 2015 Apr;13(4):699-712. doi: 10.1158/1541-7786.MCR-14-0422. Epub 2015 Mar 31. PubMed |
Targeting c-MYC in Platinum-Resistant Ovarian Cancer. Reyes-Gonzalez JM, Armaiz-Pena GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarria-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejia PE. Mol Cancer Ther. 2015 Oct;14(10):2260-9. doi: 10.1158/1535-7163.MCT-14-0801. Epub 2015 Jul 30. PubMed |
Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Neurobiol Dis. 2016 Feb;86:16-28. doi: 10.1016/j.nbd.2015.11.017. Epub 2015 Nov 29. PubMed |
c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells. Hahm ER, Singh KB, Singh SV. Cell Cycle. 2016 Sep;15(17):2309-20. doi: 10.1080/15384101.2016.1201253. Epub 2016 Jun 24. PubMed |
Erythropoietin drives breast cancer progression by activation of its receptor EPOR. Chan KK, Matchett KB, Coulter JA, Yuen HF, McCrudden CM, Zhang SD, Irwin GW, Davidson MA, Rulicke T, Schober S, Hengst L, Jaekel H, Platt-Higgins A, Rudland PS, Mills KI, Maxwell P, El-Tanani M, Lappin TR. Oncotarget. 2017 Jun 13;8(24):38251-38263. doi: 10.18632/oncotarget.16368. PubMed |
Arginine methylation regulates c-Myc-dependent transcription by altering promoter recruitment of the acetyltransferase p300. Tikhanovich I, Zhao J, Bridges B, Kumer S, Roberts B, Weinman SA. J Biol Chem. 2017 Jun 26. pii: jbc.M117.797928. doi: 10.1074/jbc.M117.797928. PubMed |
MYC expression correlates with PD-L1 expression in non-small cell lung cancer. Kim EY, Kim A, Kim SK, Chang YS. Lung Cancer. 2017 Aug;110:63-67. doi: 10.1016/j.lungcan.2017.06.006. Epub 2017 Jun 14. PubMed |
Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma. Luanpitpong S, Angsutararux P, Samart P, Chanthra N, Chanvorachote P, Issaragrisil S. Sci Rep. 2017 Sep 6;7(1):10607. doi: 10.1038/s41598-017-10886-x. PubMed |
YBX1 promotes tumor growth by elevating glycolysis in human bladder cancer. Xu L, Li H, Wu L, Huang S. Oncotarget. 2017 Jul 26;8(39):65946-65956. doi: 10.18632/oncotarget.19583. eCollection 2017 Sep 12. PubMed |
Viral E6/E7 oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines. Hoppe-Seyler K, Honegger A, Bossler F, Sponagel J, Bulkescher J, Lohrey C, Hoppe-Seyler F. Oncotarget. 2017 Nov 15;8(63):106342-106351. doi: 10.18632/oncotarget.22463. eCollection 2017 Dec 5. PubMed |
Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). Noguchi K, Dincman TA, Dalton AC, Howley BV, McCall BJ, Mohanty BK, Howe PH. J Biol Chem. 2018 Jul 20;293(29):11401-11414. doi: 10.1074/jbc.RA118.003616. Epub 2018 Jun 5. PubMed |
Genetic instability and recurrent MYC amplification in ALK-translocated NSCLC: a central role of TP53 mutations. Alidousty C, Baar T, Martelotto LG, Heydt C, Wagener S, Fassunke J, Duerbaum N, Scheel AH, Frank S, Holz B, Binot E, Kron A, Merkelbach-Bruse S, Ihle MA, Wolf J, Buettner R, Schultheis AM. J Pathol. 2018 Sep;246(1):67-76. doi: 10.1002/path.5110. Epub 2018 Jul 31. PubMed |
Dermatopontin inhibits papillary thyroid cancer cell proliferation through MYC repression. Guo Y, Li H, Guan H, Ke W, Liang W, Xiao H, Li Y. Mol Cell Endocrinol. 2019 Jan 15;480:122-132. doi: 10.1016/j.mce.2018.10.021. Epub 2018 Nov 2. PubMed |
Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma. Gerard C, Di-Luoffo M, Gonay L, Caruso S, Couchy G, Loriot A, Castven D, Tao J, Konobrocka K, Cordi S, Monga SP, Hanert E, Marquardt JU, Zucman-Rossi J, Lemaigre FP. J Hepatol. 2019 Aug;71(2):323-332. doi: 10.1016/j.jhep.2019.03.024. Epub 2019 Apr 4. PubMed |
Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence. Li JM, Huang YC, Kuo YH, Cheng CC, Kuan FC, Chang SF, Lee YR, Chin CC, Shi CS. Cancers (Basel). 2019 Jul 22;11(7). pii: cancers11071034. doi: 10.3390/cancers11071034. PubMed |
Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T. Nat Commun. 2019 Oct 17;10(1):4710. doi: 10.1038/s41467-019-12609-4. PubMed |
Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death. Mishra R, Amanullah A, Upadhyay A, Dhiman R, Dubey AR, Singh S, Prasad A, Mishra A. Int J Biochem Cell Biol. 2020 Mar;120:105697. doi: 10.1016/j.biocel.2020.105697. Epub 2020 Jan 23. PubMed |
NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. Cole AJ, Iyengar M, Panesso-Gomez S, O'Hayer P, Chan D, Delgoffe GM, Aird KM, Yoon E, Bai S, Buckanovich RJ. JCI Insight. 2020 Apr 9;5(7). pii: 131486. doi: 10.1172/jci.insight.131486. PubMed |
FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells. Ghatak S, Hascall VC, Markwald RR, Misra S. Int J Mol Sci. 2021 Jan 13;22(2). pii: ijms22020753. doi: 10.3390/ijms22020753. PubMed |
RTEL1 influences the abundance and localization of TERRA RNA. Ghisays F, Garzia A, Wang H, Canasto-Chibuque C, Hohl M, Savage SA, Tuschl T, Petrini JHJ. Nat Commun. 2021 May 21;12(1):3016. doi: 10.1038/s41467-021-23299-2. PubMed |
Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer. Hassan MS, Cwidak N, Johnson C, Daster S, Eppenberger-Castori S, Awasthi N, Li J, Schwarz MA, von Holzen U. Front Pharmacol. 2021 Sep 21;12:746385. doi: 10.3389/fphar.2021.746385. eCollection 2021. PubMed |
BRD4 Regulates Transcription Factor DeltaNp63alpha to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Fisher ML, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson JE, Goldberg GL, Mills AA. Cancer Res. 2021 Dec 15;81(24):6246-6258. doi: 10.1158/0008-5472.CAN-21-0707. Epub 2021 Oct 25. PubMed |
Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis. Haraoka Y, Akieda Y, Nagai Y, Mogi C, Ishitani T. Nat Commun. 2022 Mar 18;13(1):1417. doi: 10.1038/s41467-022-29061-6. PubMed |
Palbociclib Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells via RB-Independent STAT3 Phosphorylation. Xiang W, Qi W, Li H, Sun J, Dong C, Ou H, Liu B. Curr Oncol. 2022 Aug 18;29(8):5855-5868. doi: 10.3390/curroncol29080462. PubMed |
Generation of Functional Immortalized Human Corneal Stromal Stem Cells. Dos Santos A, Lyu N, Balayan A, Knight R, Zhuo KS, Sun Y, Xu J, Funderburgh ML, Funderburgh JL, Deng SX. Int J Mol Sci. 2022 Nov 2;23(21):13399. doi: 10.3390/ijms232113399. PubMed |
NUDT22 promotes cancer growth through pyrimidine salvage. Walter M, Mayr F, Hanna BMF, Cookson V, Mortusewicz O, Helleday T, Herr P. Oncogene. 2023 Apr;42(16):1282-1293. doi: 10.1038/s41388-023-02643-4. Epub 2023 Mar 4. PubMed |
Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1. Omar FA, Brown TC, Gillanders WE, Fleming TP, Smith MA, Bremner RM, Sankpal NV. PLoS One. 2023 May 16;18(5):e0285707. doi: 10.1371/journal.pone.0285707. eCollection 2023. PubMed |
CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion. Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D. J Clin Invest. 2023 Dec 1;133(23):e167728. doi: 10.1172/JCI167728. PubMed |
Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma. Ye T, Mishra AK, Banday S, Li R, Hu K, Coleman MM, Shan Y, Chowdhury SR, Zhou L, Pak ML, Simone TM, Malonia SK, Zhu LJ, Kelliher MA, Green MR. Cell Rep. 2024 May 28;43(5):114211. doi: 10.1016/j.celrep.2024.114211. Epub 2024 May 8. PubMed |
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