pET28a 6xHis PreScission SARS-CoV-2 nsp13 Citations (2)
Originally described in: Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait B, Kapoor T, Darst SA, Campbell EA bioRxiv. 2020 Jul 13. doi: 10.1101/2020.07.08.194084. PubMed Journal
Articles Citing pET28a 6xHis PreScission SARS-CoV-2 nsp13
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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y, Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst SA. Nat Struct Mol Biol. 2022 Mar;29(3):250-260. doi: 10.1038/s41594-022-00734-6. Epub 2022 Mar 8. PubMed |
A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance. Grimes SL, Choi YJ, Banerjee A, Small G, Anderson-Daniels J, Gribble J, Pruijssers AJ, Agostini ML, Abu-Shmais A, Lu X, Darst SA, Campbell E, Denison MR. mBio. 2023 Aug 31;14(4):e0106023. doi: 10.1128/mbio.01060-23. Epub 2023 Jun 20. PubMed |
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