pBABE YAP1 Citations (15)
Originally described in: Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon.Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA Proc Natl Acad Sci U S A. 2006 Aug 15. 103(33):12405-10. PubMed Journal
Articles Citing pBABE YAP1
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Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP.
Angus L, Moleirinho S, Herron L, Sinha A, Zhang X, Niestrata M, Dholakia K, Prystowsky MB, Harvey KF, Reynolds PA, Gunn-Moore FJ.
Oncogene. 2012 Jan 12;31(2):238-50. doi: 10.1038/onc.2011.224. Epub 2011 Jun 13.
PubMed
Associated Plasmids |
| YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A, Zhang H, Karlan B, Greene MI, Wang Q. Oncogene. 2013 Apr 25;32(17):2220-9. doi: 10.1038/onc.2012.231. Epub 2012 Jun 11. PubMed |
| Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts. Moleirinho S, Patrick C, Tilston-Lunel AM, Higginson JR, Angus L, Antkowiak M, Barnett SC, Prystowsky MB, Reynolds PA, Gunn-Moore FJ. PLoS One. 2013 Apr 8;8(4):e60028. doi: 10.1371/journal.pone.0060028. Print 2013. PubMed |
| Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. Sanidas I, Polytarchou C, Hatziapostolou M, Ezell SA, Kottakis F, Hu L, Guo A, Xie J, Comb MJ, Iliopoulos D, Tsichlis PN. Mol Cell. 2014 Feb 20;53(4):577-90. doi: 10.1016/j.molcel.2013.12.018. Epub 2014 Jan 23. PubMed |
| Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma. Slemmons KK, Crose LE, Rudzinski E, Bentley RC, Linardic CM. PLoS One. 2015 Oct 23;10(10):e0140781. doi: 10.1371/journal.pone.0140781. eCollection 2015. PubMed |
| ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP. Muranen T, Selfors LM, Hwang J, Gallegos LL, Coloff JL, Thoreen CC, Kang SA, Sabatini DM, Mills GB, Brugge JS. Cancer Res. 2016 Dec 15;76(24):7168-7180. Epub 2016 Oct 20. PubMed |
| Verteporfin induces apoptosis and eliminates cancer stem-like cells in uveal melanoma in the absence of light activation. Ma YW, Liu YZ, Pan JX. Am J Cancer Res. 2016 Dec 1;6(12):2816-2830. eCollection 2016. PubMed |
| The cell polarity protein Scrib functions as a tumor suppressor in liver cancer. Kapil S, Sharma BK, Patil M, Elattar S, Yuan J, Hou SX, Kolhe R, Satyanarayana A. Oncotarget. 2017 Apr 18;8(16):26515-26531. doi: 10.18632/oncotarget.15713. PubMed |
| A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma. Sun J, Wang X, Tang B, Liu H, Zhang M, Wang Y, Ping F, Ding J, Shen A, Geng M. Theranostics. 2018 May 11;8(12):3256-3267. doi: 10.7150/thno.23964. eCollection 2018. PubMed |
| Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer. Schaal CM, Bora-Singhal N, Kumar DM, Chellappan SP. Mol Cancer. 2018 Oct 15;17(1):149. doi: 10.1186/s12943-018-0901-2. PubMed |
| A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas. Murakami S, Nemazanyy I, White SM, Chen H, Nguyen CDK, Graham GT, Saur D, Pende M, Yi C. Dev Cell. 2019 Oct 7;51(1):113-128.e9. doi: 10.1016/j.devcel.2019.07.022. Epub 2019 Aug 22. PubMed |
| Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK-rearranged lung cancer. Yun MR, Choi HM, Lee YW, Joo HS, Park CW, Choi JW, Kim DH, Kang HN, Pyo KH, Shin EJ, Shim HS, Soo RA, Yang JC, Lee SS, Chang H, Kim MH, Hong MH, Kim HR, Cho BC. EMBO Mol Med. 2019 Dec;11(12):e10581. doi: 10.15252/emmm.201910581. Epub 2019 Oct 21. PubMed |
| Epithelial cell transforming 2 is regulated by Yes-associated protein 1 and mediates pancreatic cancer progression and metastasis. Li C, Peng Z, Wang Y, Lam G, Nissen N, Tang J, Yuan X, Lewis M, Greene MI, Pandol SJ, Wang Q. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G380-G395. doi: 10.1152/ajpgi.00185.2020. Epub 2021 Jan 27. PubMed |
| YAP1-mediated regulation of mitochondrial dynamics in IDH1 mutant gliomas. Patrick S, Gowda P, Lathoria K, Suri V, Sen E. J Cell Sci. 2021 Nov 15;134(22). pii: 273515. doi: 10.1242/jcs.259188. Epub 2021 Nov 24. PubMed |
| Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms. Safari M, Scotto L, Litman T, Petrukhin LA, Zhu H, Shen M, Robey RW, Hall MD, Fojo T, Bates SE. Cancers (Basel). 2023 Oct 12;15(20):4960. doi: 10.3390/cancers15204960. PubMed |
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