pBabe-Puro-IKBalpha-mut (super repressor) Citations (39)
Originally described in: Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene.Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC Cell. 2007 Jun 15. 129(6):1065-1079. PubMed Journal
Articles Citing pBabe-Puro-IKBalpha-mut (super repressor)
| Articles |
|---|
| Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway. Li J, Gong LY, Song LB, Jiang LL, Liu LP, Wu J, Yuan J, Cai JC, He M, Wang L, Zeng M, Cheng SY, Li M. Am J Pathol. 2010 Feb;176(2):699-709. doi: 10.2353/ajpath.2010.090502. Epub 2009 Dec 24. PubMed |
| Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3K/Akt/NF-kappaB pathway in human non-small cell lung cancer. Song L, Xiong H, Li J, Liao W, Wang L, Wu J, Li M. Clin Cancer Res. 2011 Apr 1;17(7):1839-49. doi: 10.1158/1078-0432.CCR-10-0720. Epub 2011 Feb 15. PubMed |
| Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1beta via late phase activation of nuclear factor kappaB and expression of phagocyte-type NADPH oxidase. Yoshimura K, Miyamoto Y, Yasuhara R, Maruyama T, Akiyama T, Yamada A, Takami M, Suzawa T, Tsunawaki S, Tachikawa T, Baba K, Kamijo R. J Biol Chem. 2011 Apr 29;286(17):14744-52. doi: 10.1074/jbc.M111.221259. Epub 2011 Mar 3. PubMed |
| Dose-specific effects of tumor necrosis factor alpha on osteogenic differentiation of mesenchymal stem cells. Huang H, Zhao N, Xu X, Xu Y, Li S, Zhang J, Yang P. Cell Prolif. 2011 Oct;44(5):420-7. doi: 10.1111/j.1365-2184.2011.00769.x. PubMed |
| Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression. Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA. Cancer Res. 2012 May 1;72(9):2251-61. doi: 10.1158/0008-5472.CAN-11-3386. Epub 2012 Mar 15. PubMed |
| A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy. Homer CR, Kabi A, Marina-Garcia N, Sreekumar A, Nesvizhskii AI, Nickerson KP, Chinnaiyan AM, Nunez G, McDonald C. J Biol Chem. 2012 Jul 20;287(30):25565-76. doi: 10.1074/jbc.M111.326835. Epub 2012 Jun 4. PubMed |
| Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells. Kamran N, Takai Y, Miyoshi J, Biswas SK, Wong JS, Gasser S. PLoS One. 2013;8(1):e54406. doi: 10.1371/journal.pone.0054406. Epub 2013 Jan 17. PubMed |
| EpCAM modulates NF-kappaB signaling and interleukin-8 expression in breast cancer. Sankpal NV, Fleming TP, Gillanders WE. Mol Cancer Res. 2013 Apr;11(4):418-26. doi: 10.1158/1541-7786.MCR-12-0518. Epub 2013 Feb 1. PubMed |
| The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-alpha expression. Robbs BK, Lucena PI, Viola JP. Biochim Biophys Acta. 2013 Aug;1833(8):2016-28. doi: 10.1016/j.bbamcr.2013.04.003. Epub 2013 Apr 10. PubMed |
| Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-kappaB. Park SH, Riley P 4th, Frisch SM. Apoptosis. 2013 Aug;18(8):949-62. doi: 10.1007/s10495-013-0847-1. PubMed |
| Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes. Flusberg DA, Roux J, Spencer SL, Sorger PK. Mol Biol Cell. 2013 Jul;24(14):2186-200. doi: 10.1091/mbc.E12-10-0737. Epub 2013 May 22. PubMed |
| Synergistic anticancer effects of Pam3CSK4 and Ara-C on B-cell lymphoma cells. Lee SK, Chwee JY, Ma CA, Le Bert N, Huang CW, Gasser S. Clin Cancer Res. 2014 Jul 1;20(13):3485-95. doi: 10.1158/1078-0432.CCR-13-2522. Epub 2014 May 5. PubMed |
| TBLR1 is a novel prognostic marker and promotes epithelial-mesenchymal transition in cervical cancer. Wang J, Ou J, Guo Y, Dai T, Li X, Liu J, Xia M, Liu L, He M. Br J Cancer. 2014 Jul 8;111(1):112-24. doi: 10.1038/bjc.2014.278. Epub 2014 May 29. PubMed |
| Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma cell aggressiveness by activating the NF-kappaB pathway. Dai T, Zhang D, Cai M, Wang C, Wu Z, Ying Z, Wu J, Li M, Xie D, Li J, Song L. J Pathol. 2015 Feb;235(3):490-501. doi: 10.1002/path.4479. PubMed |
| AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-kappaB signaling pathway in hepatocellular carcinoma. Cui Y, Lin C, Wu Z, Liu A, Zhang X, Zhu J, Wu G, Wu J, Li M, Li J, Song L. Oncotarget. 2014 Dec 15;5(23):12057-69. PubMed |
| MicroRNA-500 sustains nuclear factor-kappaB activation and induces gastric cancer cell proliferation and resistance to apoptosis. Zhang L, Ding Y, Yuan Z, Liu J, Sun J, Lei F, Wu S, Li S, Zhang D. Oncotarget. 2015 Feb 10;6(4):2483-95. PubMed |
| URG4/URGCP enhances the angiogenic capacity of human hepatocellular carcinoma cells in vitro via activation of the NF-kappaB signaling pathway. Xing S, Zhang B, Hua R, Tai WC, Zeng Z, Xie B, Huang C, Xue J, Xiong S, Yang J, Liu S, Li H. BMC Cancer. 2015 May 7;15:368. doi: 10.1186/s12885-015-1378-7. PubMed |
| The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1beta and NF-kappaB signaling. Trinh BQ, Barengo N, Kim SB, Lee JS, Zweidler-McKay PA, Naora H. J Cell Sci. 2015 Aug 15;128(16):3055-67. doi: 10.1242/jcs.168187. Epub 2015 Jul 24. PubMed |
| Overexpression of TRIM14 promotes tongue squamous cell carcinoma aggressiveness by activating the NF-kappaB signaling pathway. Su X, Wang J, Chen W, Li Z, Fu X, Yang A. Oncotarget. 2016 Mar 1;7(9):9939-50. doi: 10.18632/oncotarget.6941. PubMed |
| IKKbeta promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. PubMed |
| Overexpression of G protein-coupled receptor GPR87 promotes pancreatic cancer aggressiveness and activates NF-kappaB signaling pathway. Wang L, Zhou W, Zhong Y, Huo Y, Fan P, Zhan S, Xiao J, Jin X, Gou S, Yin T, Wu H, Liu T. Mol Cancer. 2017 Mar 14;16(1):61. doi: 10.1186/s12943-017-0627-6. PubMed |
| NFkappaB-Mediated Invasiveness in CD133(+) Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling. Nomura A, Gupta VK, Dauer P, Sharma NS, Dudeja V, Merchant N, Saluja AK, Banerjee S. Mol Cancer Res. 2018 Jan;16(1):162-172. doi: 10.1158/1541-7786.MCR-17-0221. Epub 2017 Sep 28. PubMed |
| The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-kappaB signaling pathway. He S, Niu G, Shang J, Deng Y, Wan Z, Zhang C, You Z, Shen H. J Exp Clin Cancer Res. 2017 Oct 4;36(1):137. doi: 10.1186/s13046-017-0607-0. PubMed |
| The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway. Warnier M, Flaman JM, Chouabe C, Wiel C, Gras B, Griveau A, Blanc E, Foy JP, Mathot P, Saintigny P, Van Coppenolle F, Vindrieux D, Martin N, Bernard D. Aging Cell. 2018 Jun;17(3):e12736. doi: 10.1111/acel.12736. Epub 2018 Feb 15. PubMed |
| CNPY2 enhances resistance to apoptosis induced by cisplatin via activation of NF-kappaB pathway in human non-small cell lung cancer. Yu D, Qin Y, Jun-Qiang L, Shun-Lin G. Biomed Pharmacother. 2018 Jul;103:1658-1663. doi: 10.1016/j.biopha.2018.04.123. Epub 2018 May 14. PubMed |
| NF-kappaB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. Cancer Discov. 2018 Jul;8(7):850-865. doi: 10.1158/2159-8290.CD-17-1211. Epub 2018 Jun 6. PubMed |
| Oncogenic TRIM31 confers gemcitabine resistance in pancreatic cancer via activating the NF-kappaB signaling pathway. Yu C, Chen S, Guo Y, Sun C. Theranostics. 2018 May 11;8(12):3224-3236. doi: 10.7150/thno.23259. eCollection 2018. PubMed |
| The lncRNA BORG facilitates the survival and chemoresistance of triple-negative breast cancers. Gooding AJ, Zhang B, Gunawardane L, Beard A, Valadkhan S, Schiemann WP. Oncogene. 2019 Mar;38(12):2020-2041. doi: 10.1038/s41388-018-0586-4. Epub 2018 Nov 22. PubMed |
| Tumor-Associated Macrophages Induce Endocrine Therapy Resistance in ER+ Breast Cancer Cells. Castellaro AM, Rodriguez-Baili MC, Di Tada CE, Gil GA. Cancers (Basel). 2019 Feb 6;11(2). pii: cancers11020189. doi: 10.3390/cancers11020189. PubMed |
| Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-kappaB Pathway in Preclinical Models of Pediatric High-Grade Glioma. DeSisto JA, Flannery P, Lemma R, Pathak A, Mestnik S, Philips N, Bales NJ, Kashyap T, Moroze E, Venkataraman S, Kung AL, Carter BD, Landesman Y, Vibhakar R, Green AL. Mol Cancer Ther. 2020 Feb;19(2):540-551. doi: 10.1158/1535-7163.MCT-18-1319. Epub 2019 Oct 8. PubMed |
| BGN/TLR4/NF-B Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells. Huang HC, Cai BH, Suen CS, Lee HY, Hwang MJ, Liu FT, Kannagi R. Cells. 2020 Feb 9;9(2). pii: cells9020397. doi: 10.3390/cells9020397. PubMed |
| NF-kappaB Blockade with Oral Administration of Dimethylaminoparthenolide (DMAPT), Delays Prostate Cancer Resistance to Androgen Receptor (AR) Inhibition and Inhibits AR Variants. Morel KL, Hamid AA, Clohessy JG, Pandell N, Ellis L, Sweeney CJ. Mol Cancer Res. 2021 Jul;19(7):1137-1145. doi: 10.1158/1541-7786.MCR-21-0099. Epub 2021 Apr 16. PubMed |
| HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers. Di Giorgio E, Paluvai H, Dalla E, Ranzino L, Renzini A, Moresi V, Minisini M, Picco R, Brancolini C. Genome Biol. 2021 May 10;22(1):129. doi: 10.1186/s13059-021-02340-z. PubMed |
| Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. EBioMedicine. 2021 Dec;74:103712. doi: 10.1016/j.ebiom.2021.103712. Epub 2021 Nov 25. PubMed |
| Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1. Oreskovic E, Wheeler EC, Mengwasser KE, Fujimura E, Martin TD, Tothova Z, Elledge SJ. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7). pii: 2120540119. doi: 10.1073/pnas.2120540119. PubMed |
| Dynamic regulation of myofibroblast phenotype in cellular senescence. Lopez-Antona I, Contreras-Jurado C, Luque-Martin L, Carpintero-Leyva A, Gonzalez-Mendez P, Palmero I. Aging Cell. 2022 Apr;21(4):e13580. doi: 10.1111/acel.13580. Epub 2022 Mar 9. PubMed |
| Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance. Yin K, Patten D, Gough S, de Barros Goncalves S, Chan A, Olan I, Cassidy L, Poblocka M, Zhu H, Lun A, Schuijs M, Young A, Martinez-Jimenez C, Halim TYF, Shetty S, Narita M, Hoare M. Genes Dev. 2022 May 1;36(9-10):533-549. doi: 10.1101/gad.349585.122. Epub 2022 May 26. PubMed |
| NF-kappaB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells. Raynard C, Ma X, Huna A, Tessier N, Massemin A, Zhu K, Flaman JM, Moulin F, Goehrig D, Medard JJ, Vindrieux D, Treilleux I, Hernandez-Vargas H, Ducreux S, Martin N, Bernard D. Aging Cell. 2022 Jul;21(7):e13632. doi: 10.1111/acel.13632. Epub 2022 Jun 2. PubMed |
| PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer. Wang Z, Wu S, Chen X, Liang J, Xue F, Cho WC, Bao J, Chen B, Ye M, Ma D, Zhu C, Zhu J, Shen J. Transl Lung Cancer Res. 2023 Nov 30;12(11):2294-2309. doi: 10.21037/tlcr-23-567. Epub 2023 Nov 24. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.