pBabe-Puro-BRAF-V600E Citations (23)

Originally described in: Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC Cell. 2007 Jun 15. 129(6):1065-1079. PubMed Journal

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Articles Citing pBabe-Puro-BRAF-V600E

Articles
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. Clin Cancer Res. 2011 Jun 1;17(11):3590-9. doi: 10.1158/1078-0432.CCR-10-3349. PubMed
Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain. Wagenaar TR, Ma L, Roscoe B, Park SM, Bolon DN, Green MR. Pigment Cell Melanoma Res. 2014 Jan;27(1):124-33. doi: 10.1111/pcmr.12171. Epub 2013 Oct 15. PubMed
RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis. Li S, Mattar P, Dixit R, Lawn SO, Wilkinson G, Kinch C, Eisenstat D, Kurrasch DM, Chan JA, Schuurmans C. J Neurosci. 2014 Feb 5;34(6):2169-90. doi: 10.1523/JNEUROSCI.4077-13.2014. PubMed
miR-146a promotes the initiation and progression of melanoma by activating Notch signaling. Forloni M, Dogra SK, Dong Y, Conte D Jr, Ou J, Zhu LJ, Deng A, Mahalingam M, Green MR, Wajapeyee N. Elife. 2014 Feb 18;3:e01460. doi: 10.7554/eLife.01460. PubMed
The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. Fang M, Ou J, Hutchinson L, Green MR. Mol Cell. 2014 Sep 18;55(6):904-15. doi: 10.1016/j.molcel.2014.08.010. Epub 2014 Sep 11. PubMed
Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis. Hellesoy M, Lorens JB. Mol Biol Cell. 2015 Jul 15;26(14):2698-711. doi: 10.1091/mbc.E14-09-1378. Epub 2015 May 28. PubMed
Potential role of AKT/mTOR signalling proteins in hairy cell leukaemia: association with BRAF/ERK activation and clinical outcome. Lakiotaki E, Levidou G, Angelopoulou MK, Adamopoulos C, Pangalis G, Rassidakis G, Vassilakopoulos T, Gainaru G, Flevari P, Sachanas S, Saetta AA, Sepsa A, Moschogiannis M, Kalpadakis C, Tsesmetzis N, Milionis V, Chatziandreou I, Thymara I, Panayiotidis P, Dimopoulou M, Plata E, Konstantopoulos K, Patsouris E, Piperi C, Korkolopoulou P. Sci Rep. 2016 Feb 19;6:21252. doi: 10.1038/srep21252. PubMed
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs. Hafner M, Niepel M, Chung M, Sorger PK. Nat Methods. 2016 Jun;13(6):521-7. doi: 10.1038/nmeth.3853. Epub 2016 May 2. PubMed
Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgfbeta, and Erk Signaling. Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, Daftarian N, Biernaskie J, McFarlane S, Schuurmans C. J Neurosci. 2016 Sep 7;36(36):9454-71. doi: 10.1523/JNEUROSCI.0936-16.2016. PubMed
Interferon alpha-inducible protein 6 regulates NRASQ61K-induced melanomagenesis and growth. Gupta R, Forloni M, Bisserier M, Dogra SK, Yang Q, Wajapeyee N. Elife. 2016 Sep 8;5. pii: e16432. doi: 10.7554/eLife.16432. PubMed
Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer. Kawakami H, Huang S, Pal K, Dutta SK, Mukhopadhyay D, Sinicrope FA. Mol Cancer Ther. 2016 Dec;15(12):3015-3027. Epub 2016 Oct 7. PubMed
Activation of MAPK/ERK signaling by Burkholderia pseudomallei cycle inhibiting factor (Cif). Ng MY, Wang M, Casey PJ, Gan YH, Hagen T. PLoS One. 2017 Feb 6;12(2):e0171464. doi: 10.1371/journal.pone.0171464. eCollection 2017. PubMed
Multivalent Small-Molecule Pan-RAS Inhibitors. Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. PubMed
Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3Kalpha-selective Inhibitors in Breast Cancer. Xu YC, Wang X, Chen Y, Chen SM, Yang XY, Sun YM, Geng MY, Ding J, Meng LH. Theranostics. 2017 Feb 23;7(4):974-986. doi: 10.7150/thno.17830. eCollection 2017. PubMed
Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer. Liu R, Zhang T, Zhu G, Xing M. Nat Commun. 2018 Feb 8;9(1):579. doi: 10.1038/s41467-018-03033-1. PubMed
Characterisation of cellular effects of Burkholderia pseudomallei cycle inhibiting factor (Cif). Ng MY, Gan YH, Hagen T. Biol Open. 2018 Jul 16;7(7). pii: bio.028225. doi: 10.1242/bio.028225. PubMed
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Li S, Song Y, Quach C, Guo H, Jang GB, Maazi H, Zhao S, Sands NA, Liu Q, In GK, Peng D, Yuan W, Machida K, Yu M, Akbari O, Hagiya A, Yang Y, Punj V, Tang L, Liang C. Nat Commun. 2019 Apr 12;10(1):1693. doi: 10.1038/s41467-019-09634-8. PubMed
BRAF(V600E)-induced KRT19 expression in thyroid cancer promotes lymph node metastasis via EMT. Wang X, Xu X, Peng C, Qin Y, Gao T, Jing J, Zhao H. Oncol Lett. 2019 Jul;18(1):927-935. doi: 10.3892/ol.2019.10360. Epub 2019 May 14. PubMed
Oncogenic Ras mutant causes the hyperactivation of NF-kappaB via acceleration of its transcriptional activation. Tago K, Funakoshi-Tago M, Ohta S, Kawata H, Saitoh H, Horie H, Aoki-Ohmura C, Yamauchi J, Tanaka A, Matsugi J, Yanagisawa K. Mol Oncol. 2019 Nov;13(11):2493-2510. doi: 10.1002/1878-0261.12580. Epub 2019 Oct 18. PubMed
Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer. Schaufler D, Ast DF, Tumbrink HL, Abedpour N, Maas L, Schwabe AE, Spille I, Lennartz S, Fassunke J, Aldea M, Besse B, Planchard D, Nogova L, Michels S, Kobe C, Persigehl T, Westphal T, Koleczko S, Fischer R, Weber JP, Altmuller J, Thomas RK, Merkelbach-Bruse S, Gautschi O, Mezquita L, Buttner R, Wolf J, Peifer M, Bragelmann J, Scheffler M, Sos ML. NPJ Precis Oncol. 2021 Dec 17;5(1):102. doi: 10.1038/s41698-021-00241-9. PubMed
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K. Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schulein-Volk C, Buchberger A, Calzado Canale MA, Rosenfeldt M, Dikic I, Munch C, Diefenbacher ME. Mol Oncol. 2022 Sep;16(17):3082-3106. doi: 10.1002/1878-0261.13217. Epub 2022 Apr 30. PubMed
Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction. Chen JY, Hug C, Reyes J, Tian C, Gerosa L, Frohlich F, Ponsioen B, Snippert HJG, Spencer SL, Jambhekar A, Sorger PK, Lahav G. Cell Rep. 2023 Mar 28;42(3):112252. doi: 10.1016/j.celrep.2023.112252. Epub 2023 Mar 14. PubMed
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway. Weatherdon L, Stuart K, Cassidy M, de la Gandara AM, Okkenhaug H, Muellener M, Mckenzie G, Cook SJ, Gilley R. Biochem J. 2024 Mar 20;481(6):405-422. doi: 10.1042/BCJ20240015. PubMed

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