pEGFP hsp70 Citations (36)
Originally described in: Hsp70 dynamics in vivo: effect of heat shock and protein aggregation.Zeng XC, Bhasin S, Wu X, Lee JG, Maffi S, Nichols CJ, Lee KJ, Taylor JP, Greene LE, Eisenberg E J Cell Sci. 2004 Oct 1. 117(Pt 21):4991-5000. PubMed Journal
Articles Citing pEGFP hsp70
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E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. Mishra A, Maheshwari M, Chhangani D, Fujimori-Tonou N, Endo F, Joshi AP, Jana NR, Yamanaka K. Neurobiol Aging. 2013 Apr;34(4):1310.e11-23. doi: 10.1016/j.neurobiolaging.2012.08.016. Epub 2012 Oct 4. PubMed |
Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy. Kukreti H, Amuthavalli K, Harikumar A, Sathiyamoorthy S, Feng PZ, Anantharaj R, Tan SL, Lokireddy S, Bonala S, Sriram S, McFarlane C, Kambadur R, Sharma M. J Biol Chem. 2013 Mar 1;288(9):6663-78. doi: 10.1074/jbc.M112.390369. Epub 2013 Jan 6. PubMed |
Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Chhangani D, Mishra A. Sci Rep. 2013;3:1972. doi: 10.1038/srep01972. PubMed |
A protective Hsp70-TLR4 pathway in lethal oxidant lung injury. Zhang Y, Zhang X, Shan P, Hunt CR, Pandita TK, Lee PJ. J Immunol. 2013 Aug 1;191(3):1393-403. doi: 10.4049/jimmunol.1300052. Epub 2013 Jul 1. PubMed |
VER-155008, a small molecule inhibitor of HSP70 with potent anti-cancer activity on lung cancer cell lines. Wen W, Liu W, Shao Y, Chen L. Exp Biol Med (Maywood). 2014 May;239(5):638-45. doi: 10.1177/1535370214527899. Epub 2014 Mar 27. PubMed |
DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency. Garrod TJ, Grubor-Bauk B, Gargett T, Li Y, Miller DS, Yu W, Major L, Burrell CJ, Wesselingh S, Suhrbier A, Gowans EJ. Eur J Immunol. 2014 Jul;44(7):1992-2002. doi: 10.1002/eji.201343983. Epub 2014 May 11. PubMed |
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, Mishra A. Biochim Biophys Acta. 2014 Sep;1842(9):1472-84. doi: 10.1016/j.bbadis.2014.04.014. Epub 2014 Apr 24. PubMed |
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70. Howe MK, Bodoor K, Carlson DA, Hughes PF, Alwarawrah Y, Loiselle DR, Jaeger AM, Darr DB, Jordan JL, Hunter LM, Molzberger ET, Gobillot TA, Thiele DJ, Brodsky JL, Spector NL, Haystead TA. Chem Biol. 2014 Dec 18;21(12):1648-59. doi: 10.1016/j.chembiol.2014.10.016. Epub 2014 Dec 11. PubMed |
A Novel Function of Molecular Chaperone HSP70: SUPPRESSION OF ONCOGENIC FOXM1 AFTER PROTEOTOXIC STRESS. Halasi M, Varaljai R, Benevolenskaya E, Gartel AL. J Biol Chem. 2016 Jan 1;291(1):142-8. doi: 10.1074/jbc.M115.678227. Epub 2015 Nov 11. PubMed |
Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Neurobiol Dis. 2016 Feb;86:16-28. doi: 10.1016/j.nbd.2015.11.017. Epub 2015 Nov 29. PubMed |
Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction. Upadhyay A, Amanullah A, Chhangani D, Joshi V, Mishra R, Mishra A. Mol Neurobiol. 2015 Dec 15. PubMed |
Proteasomal Dysfunction Induced By Diclofenac Engenders Apoptosis Through Mitochondrial Pathway. Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A. J Cell Biochem. 2016 Aug 2. doi: 10.1002/jcb.25666. PubMed |
Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Seo BR, Min KJ, Woo SM, Choe M, Choi KS, Lee YK, Yoon G, Kwon TK. Antioxid Redox Signal. 2017 Jan 9. doi: 10.1089/ars.2016.6749. PubMed |
Indomethacin Elicits Proteasomal Dysfunctions Develops Apoptosis Through Mitochondrial Abnormalities. Amanullah A, Mishra R, Upadhyay A, Reddy PP, Das R, Mishra A. J Cell Physiol. 2017 Jul 6. doi: 10.1002/jcp.26081. PubMed |
Fluorescent-Linked Enzyme Chemoproteomic Strategy (FLECS) for Identifying HSP70 Inhibitors. Haystead TAJ. Methods Mol Biol. 2018;1709:75-86. doi: 10.1007/978-1-4939-7477-1_6. PubMed |
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression. Seo SU, Woo SM, Min KJ, Kwon TK. Biochem Biophys Res Commun. 2018 Apr 15;498(4):849-854. doi: 10.1016/j.bbrc.2018.03.068. Epub 2018 Mar 13. PubMed |
mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy. Seo SU, Woo SM, Lee HS, Kim SH, Min KJ, Kwon TK. Oncogene. 2018 Sep;37(38):5205-5220. doi: 10.1038/s41388-018-0345-6. Epub 2018 May 30. PubMed |
The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts. El Buri A, Adams DR, Smith D, Tate RJ, Mullin M, Pyne S, Pyne NJ. Oncotarget. 2018 Jun 29;9(50):29453-29467. doi: 10.18632/oncotarget.25658. eCollection 2018 Jun 29. PubMed |
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress. Seo SU, Min KJ, Woo SM, Kwon TK. Exp Mol Med. 2018 Aug 17;50(8):107. doi: 10.1038/s12276-018-0138-6. PubMed |
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells. Pujhari S, Brustolin M, Macias VM, Nissly RH, Nomura M, Kuchipudi SV, Rasgon JL. Emerg Microbes Infect. 2019;8(1):8-16. doi: 10.1080/22221751.2018.1557988. PubMed |
Content release of extracellular vesicles in a cell-free extract. Bonsergent E, Lavieu G. FEBS Lett. 2019 Jun 7. doi: 10.1002/1873-3468.13472. PubMed |
ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation. Lim S, Kim DG, Kim S. Exp Mol Med. 2019 Sep 26;51(9):112. doi: 10.1038/s12276-019-0317-0. PubMed |
Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction. Tripathi A, Thangaraj A, Chivero ET, Periyasamy P, Callen S, Burkovetskaya ME, Guo ML, Buch S. Cells. 2019 Sep 28;8(10). pii: cells8101168. doi: 10.3390/cells8101168. PubMed |
Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death. Mishra R, Amanullah A, Upadhyay A, Dhiman R, Dubey AR, Singh S, Prasad A, Mishra A. Int J Biochem Cell Biol. 2020 Mar;120:105697. doi: 10.1016/j.biocel.2020.105697. Epub 2020 Jan 23. PubMed |
Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment. Hwang HY, Cho YS, Kim JY, Yun KN, Yoo JS, Lee E, Kim I, Kwon HJ. Cancers (Basel). 2020 Feb 27;12(3). pii: cancers12030543. doi: 10.3390/cancers12030543. PubMed |
Arylquin 1, a potent Par-4 secretagogue, induces lysosomal membrane permeabilization-mediated non-apoptotic cell death in cancer cells. Min KJ, Shahriyar SA, Kwon TK. Toxicol Res. 2019 Nov 21;36(2):167-173. doi: 10.1007/s43188-019-00025-1. eCollection 2020 Apr. PubMed |
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy. Bengoechea R, Findlay AR, Bhadra AK, Shao H, Stein KC, Pittman SK, Daw JA, Gestwicki JE, True HL, Weihl CC. J Clin Invest. 2020 Aug 3;130(8):4470-4485. doi: 10.1172/JCI136167. PubMed |
HSP70 drives myoblast fusion during C2C12 myogenic differentiation. Thakur SS, Swiderski K, Chhen VL, James JL, Cranna NJ, Islam AMT, Ryall JG, Lynch GS. Biol Open. 2020 Jul 22;9(7). pii: bio.053918. doi: 10.1242/bio.053918. PubMed |
Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells. Bonsergent E, Grisard E, Buchrieser J, Schwartz O, Thery C, Lavieu G. Nat Commun. 2021 Mar 25;12(1):1864. doi: 10.1038/s41467-021-22126-y. PubMed |
Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage. Actis C, Muzio G, Autelli R. Cancers (Basel). 2021 Mar 12;13(6). pii: cancers13061252. doi: 10.3390/cancers13061252. PubMed |
HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts. Pipalia NH, Saad SZ, Subramanian K, Cross A, Al-Motawa A, Garg K, Blagg BSJ, Neckers L, Helquist P, Wiest O, Ory DS, Maxfield FR. J Lipid Res. 2021;62:100114. doi: 10.1016/j.jlr.2021.100114. Epub 2021 Sep 3. PubMed |
Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process. Tognoli ML, Dancourt J, Bonsergent E, Palmulli R, de Jong OG, Van Niel G, Rubinstein E, Vader P, Lavieu G. Commun Biol. 2023 May 17;6(1):532. doi: 10.1038/s42003-023-04911-1. PubMed |
Cholesterol and Ceramide Facilitate Membrane Fusion Mediated by the Fusion Peptide of the SARS-CoV-2 Spike Protein. Niort K, Dancourt J, Boedec E, Al Amir Dache Z, Lavieu G, Tareste D. ACS Omega. 2023 Aug 28;8(36):32729-32739. doi: 10.1021/acsomega.3c03610. eCollection 2023 Sep 12. PubMed |
Trehalose Promotes Clearance of Proteotoxic Aggregation of Neurodegenerative Disease-Associated Aberrant Proteins. Kumar P, Kinger S, Dubey AR, Jagtap YA, Choudhary A, Prasad A, Jha HC, Dhiman R, Gutti RK, Mishra A. Mol Neurobiol. 2023 Dec 7. doi: 10.1007/s12035-023-03824-8. PubMed |
Akt Is Controlled by Bag5 through a Monoubiquitination to Polyubiquitination Switch. Bracho-Valdes I, Cervantes-Villagrana RD, Beltran-Navarro YM, Olguin-Olguin A, Escobar-Islas E, Carretero-Ortega J, Olivares-Reyes JA, Reyes-Cruz G, Gutkind JS, Vazquez-Prado J. Int J Mol Sci. 2023 Dec 15;24(24):17531. doi: 10.3390/ijms242417531. PubMed |
Role of heat shock protein 70 in silibinin-induced apoptosis in bladder cancer. Wei Y, Zhuang Y, Zhang Y, Luo L, Yu B, Zeng J. J Cancer. 2024 Jan 1;15(1):79-89. doi: 10.7150/jca.88668. eCollection 2024. PubMed |
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