pLDLR-Luc (aka: pES7) Citations (11)
Originally described in: Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins.Castoreno AB, Wang Y, Stockinger W, Jarzylo LA, Du H, Pagnon JC, Shieh EC, Nohturfft A Proc Natl Acad Sci U S A. 2005 Sep 13. 102(37):13129-34. PubMed Journal
Articles Citing pLDLR-Luc (aka: pES7)
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Nerve growth factor (NGF) and pro-NGF increase low-density lipoprotein (LDL) receptors in neuronal cells partly by different mechanisms: role of LDL in neurite outgrowth. Do HT, Bruelle C, Pham DD, Jauhiainen M, Eriksson O, Korhonen LT, Lindholm D. J Neurochem. 2016 Jan;136(2):306-15. doi: 10.1111/jnc.13397. Epub 2015 Nov 19. PubMed |
p75 Neurotrophin Receptor Signaling Activates Sterol Regulatory Element-binding Protein-2 in Hepatocyte Cells via p38 Mitogen-activated Protein Kinase and Caspase-3. Pham DD, Do HT, Bruelle C, Kukkonen JP, Eriksson O, Mogollon I, Korhonen LT, Arumae U, Lindholm D. J Biol Chem. 2016 May 13;291(20):10747-58. doi: 10.1074/jbc.M116.722272. Epub 2016 Mar 16. PubMed |
Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP.
Romani P, Brian I, Santinon G, Pocaterra A, Audano M, Pedretti S, Mathieu S, Forcato M, Bicciato S, Manneville JB, Mitro N, Dupont S.
Nat Cell Biol. 2019 Mar;21(3):338-347. doi: 10.1038/s41556-018-0270-5. Epub 2019 Feb 4.
PubMed
Associated Plasmids |
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism. Bertolio R, Napoletano F, Mano M, Maurer-Stroh S, Fantuz M, Zannini A, Bicciato S, Sorrentino G, Del Sal G. Nat Commun. 2019 Mar 22;10(1):1326. doi: 10.1038/s41467-019-09152-7. PubMed |
Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells. Pham DD, Bruelle C, Thi Do H, Pajanoja C, Jin C, Srinivasan V, Olkkonen VM, Eriksson O, Jauhiainen M, Lalowski M, Lindholm D. Cell Death Dis. 2019 Jul 11;10(7):537. doi: 10.1038/s41419-019-1758-z. PubMed |
Platycodin D enhances LDLR expression and LDL uptake via down-regulation of IDOL mRNA in hepatic cells. Choi YJ, Lee SJ, Kim HI, Lee HJ, Kang SJ, Kim TY, Cheon C, Ko SG. Sci Rep. 2020 Nov 16;10(1):19834. doi: 10.1038/s41598-020-76224-w. PubMed |
MMAB promotes negative feedback control of cholesterol homeostasis. Goedeke L, Canfran-Duque A, Rotllan N, Chaube B, Thompson BM, Lee RG, Cline GW, McDonald JG, Shulman GI, Lasuncion MA, Suarez Y, Fernandez-Hernando C. Nat Commun. 2021 Nov 8;12(1):6448. doi: 10.1038/s41467-021-26787-7. PubMed |
Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2. Mai S, Zhu X, Wan EYC, Wu S, Yonathan JN, Wang J, Li Y, Ma JYW, Zuo B, Tse DY, Lo PC, Wang X, Chan KM, Wu DM, Xiong W. Development. 2022 Jul 15;149(14):dev200633. doi: 10.1242/dev.200633. Epub 2022 Jul 14. PubMed |
Resveratrol Inhibits Proliferation and Induces Autophagy by Blocking SREBP1 Expression in Oral Cancer Cells. Fukuda M, Ogasawara Y, Hayashi H, Inoue K, Sakashita H. Molecules. 2022 Nov 26;27(23):8250. doi: 10.3390/molecules27238250. PubMed |
Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection. Firpo MR, LoMascolo NJ, Petit MJ, Shah PS, Mounce BC. PLoS Pathog. 2023 Apr 18;19(4):e1011317. doi: 10.1371/journal.ppat.1011317. eCollection 2023 Apr. PubMed |
p140Cap modulates the mevalonate pathway decreasing cell migration and enhancing drug sensitivity in breast cancer cells. Centonze G, Natalini D, Grasso S, Morellato A, Salemme V, Piccolantonio A, D'Attanasio G, Savino A, Bianciotto OT, Fragomeni M, Scavuzzo A, Poncina M, Nigrelli F, De Gregorio M, Poli V, Arina P, Taverna D, Kopecka J, Dupont S, Turco E, Riganti C, Defilippi P. Cell Death Dis. 2023 Dec 20;14(12):849. doi: 10.1038/s41419-023-06357-z. PubMed |
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