VSV.G Citations (87)

Originally described in: A role for Wnt signalling in self-renewal of haematopoietic stem cells.
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL Nature. 2003 May 22. 423(6938):409-14. PubMed Journal

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Articles Citing VSV.G

Articles
Induced pluripotent stem cells from highly endangered species. Ben-Nun IF, Montague SC, Houck ML, Tran HT, Garitaonandia I, Leonardo TR, Wang YC, Charter SJ, Laurent LC, Ryder OA, Loring JF. Nat Methods. 2011 Sep 4;8(10):829-31. doi: 10.1038/nmeth.1706. PubMed
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Gallego Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, Banovich NE, Kagan CL, Burnett JE, Huang CH, Mitrano A, Chavarria CI, Friedrich Ben-Nun I, Li Y, Sabatini K, Leonardo TR, Parast M, Marques-Bonet T, Laurent LC, Loring JF, Gilad Y. Elife. 2015 Jun 23;4:e07103. doi: 10.7554/eLife.07103. PubMed
Generation of Induced Pluripotent Stem Cells from Mammalian Endangered Species. Friedrich Ben-Nun I, Montague SC, Houck ML, Ryder O, Loring JF. Methods Mol Biol. 2015;1330:101-9. doi: 10.1007/978-1-4939-2848-4_10. PubMed
Observation of Parkin-Mediated Mitophagy in Pancreatic beta-Cells. Hoshino A, Matoba S. Methods Mol Biol. 2017 May 3. doi: 10.1007/7651_2017_39. PubMed
Both cytopathic and non-cytopathic bovine viral diarrhea virus (BVDV) induced autophagy at a similar rate. Rajput MKS, Abdelsalam K, Darweesh MF, Braun LJ, Kerkvliet J, Hoppe AD, Chase CCL. Vet Immunol Immunopathol. 2017 Dec;193-194:1-9. doi: 10.1016/j.vetimm.2017.09.006. Epub 2017 Oct 2. PubMed
SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells. Liang Y, Tebaldi T, Rejeski K, Joshi P, Stefani G, Taylor A, Song Y, Vasic R, Maziarz J, Balasubramanian K, Ardasheva A, Ding A, Quattrone A, Halene S. Leukemia. 2018 Dec;32(12):2659-2671. doi: 10.1038/s41375-018-0152-7. Epub 2018 Jun 1. PubMed
Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation. Canato S, Santos JD, Carvalho AS, Aloria K, Amaral MD, Matthiesen R, Falcao AO, Farinha CM. Cell Mol Life Sci. 2018 Dec;75(24):4495-4509. doi: 10.1007/s00018-018-2896-7. Epub 2018 Jul 31. PubMed
A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3. Tajan M, Hock AK, Blagih J, Robertson NA, Labuschagne CF, Kruiswijk F, Humpton TJ, Adams PD, Vousden KH. Cell Metab. 2018 Nov 6;28(5):721-736.e6. doi: 10.1016/j.cmet.2018.07.005. Epub 2018 Aug 16. PubMed
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr. Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13. PubMed
ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH(High) Melanoma-Initiating Cells. Sarvi S, Crispin R, Lu Y, Zeng L, Hurley TD, Houston DR, von Kriegsheim A, Chen CH, Mochly-Rosen D, Ranzani M, Mathers ME, Xu X, Xu W, Adams DJ, Carragher NO, Fujita M, Schuchter L, Unciti-Broceta A, Brunton VG, Patton EE. Cell Chem Biol. 2018 Dec 20;25(12):1456-1469.e6. doi: 10.1016/j.chembiol.2018.09.005. Epub 2018 Oct 4. PubMed
Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. van Galen P, Mbong N, Kreso A, Schoof EM, Wagenblast E, Ng SWK, Krivdova G, Jin L, Nakauchi H, Dick JE. Cell Rep. 2018 Oct 30;25(5):1109-1117.e5. doi: 10.1016/j.celrep.2018.10.021. PubMed
The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Bainor AJ, Saini S, Calderon A, Casado-Polanco R, Giner-Ramirez B, Moncada C, Cantor DJ, Ernlund A, Litovchick L, David G. Cell Rep. 2018 Dec 4;25(10):2797-2807.e8. doi: 10.1016/j.celrep.2018.11.024. PubMed
FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. Yan P, Li Q, Wang L, Lu P, Suzuki K, Liu Z, Lei J, Li W, He X, Wang S, Ding J, Chan P, Zhang W, Song M, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Cell Stem Cell. 2019 Mar 7;24(3):447-461.e8. doi: 10.1016/j.stem.2018.12.002. Epub 2019 Jan 17. PubMed
Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands. Haller F, Bieg M, Will R, Korner C, Weichenhan D, Bott A, Ishaque N, Lutsik P, Moskalev EA, Mueller SK, Bahr M, Woerner A, Kaiser B, Scherl C, Haderlein M, Kleinheinz K, Fietkau R, Iro H, Eils R, Hartmann A, Plass C, Wiemann S, Agaimy A. Nat Commun. 2019 Jan 21;10(1):368. doi: 10.1038/s41467-018-08069-x. PubMed
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE. Cell. 2019 Mar 7;176(6):1265-1281.e24. doi: 10.1016/j.cell.2019.01.031. Epub 2019 Feb 28. PubMed
Cognate Interaction With CD4(+) T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype. Eisel D, Das K, Dickes E, Konig R, Osen W, Eichmuller SB. Front Immunol. 2019 Feb 22;10:219. doi: 10.3389/fimmu.2019.00219. eCollection 2019. PubMed
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias. Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, Gutierrez A. Cancer Cell. 2019 Apr 15;35(4):664-676.e7. doi: 10.1016/j.ccell.2019.03.004. PubMed
BRAF(V600E)-induced KRT19 expression in thyroid cancer promotes lymph node metastasis via EMT. Wang X, Xu X, Peng C, Qin Y, Gao T, Jing J, Zhao H. Oncol Lett. 2019 Jul;18(1):927-935. doi: 10.3892/ol.2019.10360. Epub 2019 May 14. PubMed
pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate. Jia X, Pan L, Zhu M, Hu H, Zhai L, Liu J, Hu M, Liu B, Tan M. J Proteomics. 2020 Jan 6;210:103545. doi: 10.1016/j.jprot.2019.103545. Epub 2019 Oct 15. PubMed
Tumor-derived CCL20 affects B16 melanoma growth in mice. Martin-Garcia D, Silva-Vilches C, Will R, Enk AH, Lonsdorf AS. J Dermatol Sci. 2020 Jan;97(1):57-65. doi: 10.1016/j.jdermsci.2019.12.005. Epub 2019 Dec 13. PubMed
IDO1(+) Paneth cells promote immune escape of colorectal cancer. Pflugler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, Schernthanner M, Bischl R, Herndler-Brandstetter D, Glitzner E, Moll HP, Casanova E, Timelthaler G, Sibilia M, Gnant M, Lax S, Thaler J, Muller M, Strobl B, Mohr T, Kaser A, Trajanoski Z, Heller G, Eferl R. Commun Biol. 2020 May 22;3(1):252. doi: 10.1038/s42003-020-0989-y. PubMed
Generation of Transgenic Rats using a Lentiviral Vector Approach. Koza P, Przybys J, Klejman A, Olech-Kochanczyk G, Konopka W. J Vis Exp. 2020 May 17;(159). doi: 10.3791/60570. PubMed
Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease. Alvarez-Quilon A, Wojtaszek JL, Mathieu MC, Patel T, Appel CD, Hustedt N, Rossi SE, Wallace BD, Setiaputra D, Adam S, Ohashi Y, Melo H, Cho T, Gervais C, Munoz IM, Grazzini E, Young JTF, Rouse J, Zinda M, Williams RS, Durocher D. Mol Cell. 2020 Jun 18;78(6):1152-1165.e8. doi: 10.1016/j.molcel.2020.05.021. Epub 2020 Jun 8. PubMed
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives. Tandon R, Sharp JS, Zhang F, Pomin VH, Ashpole NM, Mitra D, Jin W, Liu H, Sharma P, Linhardt RJ. bioRxiv. 2020 Jun 8. doi: 10.1101/2020.06.08.140236. PubMed
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE. Genome Biol. 2020 Jul 15;21(1):174. doi: 10.1186/s13059-020-02085-1. PubMed
Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25. Malsam J, Barfuss S, Trimbuch T, Zarebidaki F, Sonnen AF, Wild K, Scheutzow A, Rohland L, Mayer MP, Sinning I, Briggs JAG, Rosenmund C, Sollner TH. Cell Rep. 2020 Jul 21;32(3):107926. doi: 10.1016/j.celrep.2020.107926. PubMed
Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy. Hinze L, Labrosse R, Degar J, Han T, Schatoff EM, Schreek S, Karim S, McGuckin C, Sacher JR, Wagner F, Stanulla M, Yuan C, Sicinska E, Giannakis M, Ng K, Dow LE, Gutierrez A. Cancer Discov. 2020 Jul 23. pii: 2159-8290.CD-19-1472. doi: 10.1158/2159-8290.CD-19-1472. PubMed
The aryl hydrocarbon receptor promotes inflammation-induced dedifferentiation and systemic metastatic spread of melanoma cells. Mengoni M, Braun AD, Gaffal E, Tuting T. Int J Cancer. 2020 Nov 15;147(10):2902-2913. doi: 10.1002/ijc.33252. Epub 2020 Aug 31. PubMed
Time-Resolved Profiling Reveals ATF3 as a Novel Mediator of Endocrine Resistance in Breast Cancer. Borgoni S, Sofyali E, Soleimani M, Wilhelm H, Muller-Decker K, Will R, Noronha A, Beumers L, Verschure PJ, Yarden Y, Magnani L, van Kampen AHC, Moerland PD, Wiemann S. Cancers (Basel). 2020 Oct 11;12(10). pii: cancers12102918. doi: 10.3390/cancers12102918. PubMed
Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein. Tandon R, Mitra D, Sharma P, McCandless MG, Stray SJ, Bates JT, Marshall GD. Sci Rep. 2020 Nov 5;10(1):19076. doi: 10.1038/s41598-020-76135-w. PubMed
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives. Tandon R, Sharp JS, Zhang F, Pomin VH, Ashpole NM, Mitra D, McCandless MG, Jin W, Liu H, Sharma P, Linhardt RJ. J Virol. 2021 Jan 13;95(3). pii: JVI.01987-20. doi: 10.1128/JVI.01987-20. Print 2021 Jan 13. PubMed
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Rolinski M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjoras M, Saetrom P, van Loon B. Nucleic Acids Res. 2021 Feb 22;49(3):1470-1484. doi: 10.1093/nar/gkaa1289. PubMed
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy. Tajan M, Hennequart M, Cheung EC, Zani F, Hock AK, Legrave N, Maddocks ODK, Ridgway RA, Athineos D, Suarez-Bonnet A, Ludwig RL, Novellasdemunt L, Angelis N, Li VSW, Vlachogiannis G, Valeri N, Mainolfi N, Suri V, Friedman A, Manfredi M, Blyth K, Sansom OJ, Vousden KH. Nat Commun. 2021 Jan 14;12(1):366. doi: 10.1038/s41467-020-20223-y. PubMed
IFNbeta1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment. Maia A, Gu Z, Koch A, Berdiel-Acer M, Will R, Schlesner M, Wiemann S. Mol Oncol. 2021 May;15(5):1308-1329. doi: 10.1002/1878-0261.12905. Epub 2021 Feb 11. PubMed
Transcription factor competition at the gamma-globin promoters controls hemoglobin switching. Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu JY, Sakon P, Pinello L, Yuan GC, Bauer DE, Orkin SH. Nat Genet. 2021 Apr;53(4):511-520. doi: 10.1038/s41588-021-00798-y. Epub 2021 Mar 1. PubMed
Generation and Breeding of EGFP-Transgenic Marmoset Monkeys: Cell Chimerism and Implications for Disease Modeling. Drummer C, Vogt EJ, Heistermann M, Roshani B, Becker T, Matz-Rensing K, Kues WA, Kugler S, Behr R. Cells. 2021 Feb 27;10(3). pii: cells10030505. doi: 10.3390/cells10030505. PubMed
Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus. Yan L, Song Y, Xia K, He P, Zhang F, Chen S, Pouliot R, Weiss DJ, Tandon R, Bates JT, Ederer DR, Mitra D, Sharma P, Davis A, Linhardt RJ. Carbohydr Polym. 2021 May 15;260:117797. doi: 10.1016/j.carbpol.2021.117797. Epub 2021 Feb 14. PubMed
Klotho inhibits neuronal senescence in human brain organoids. Shaker MR, Aguado J, Chaggar HK, Wolvetang EJ. NPJ Aging Mech Dis. 2021 Aug 2;7(1):18. doi: 10.1038/s41514-021-00070-x. PubMed
Tumor cell intrinsic Toll-like receptor 4 signaling promotes melanoma progression and metastatic dissemination. Rogava M, Braun AD, van der Sluis TC, Shridhar N, Tuting T, Gaffal E. Int J Cancer. 2022 Jan 1;150(1):142-151. doi: 10.1002/ijc.33804. Epub 2021 Sep 29. PubMed
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, Nevo E, Seluanov A, Gorbunova V. Nat Immunol. 2021 Oct;22(10):1219-1230. doi: 10.1038/s41590-021-01027-8. Epub 2021 Sep 23. PubMed
Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro. Eisele BS, Luka Z, Wu AJ, Yang F, Hale AT, York JD. J Biol Chem. 2021 Nov;297(5):101293. doi: 10.1016/j.jbc.2021.101293. Epub 2021 Oct 8. PubMed
RNA modifications detection by comparative Nanopore direct RNA sequencing. Leger A, Amaral PP, Pandolfini L, Capitanchik C, Capraro F, Miano V, Migliori V, Toolan-Kerr P, Sideri T, Enright AJ, Tzelepis K, van Werven FJ, Luscombe NM, Barbieri I, Ule J, Fitzgerald T, Birney E, Leonardi T, Kouzarides T. Nat Commun. 2021 Dec 10;12(1):7198. doi: 10.1038/s41467-021-27393-3. PubMed
A Dual HiBiT-GFP-LC3 Lentiviral Reporter for Autophagy Flux Assessment. Will R, Bauer K, Kudla M, Montero-Vergara J, Wiemann S, Jendrossek V, Pena-Llopis S, Vega-Rubin-de-Celis S. Methods Mol Biol. 2022;2445:75-98. doi: 10.1007/978-1-0716-2071-7_6. PubMed
Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium. Padonou F, Gonzalez V, Provin N, Yayilkan S, Jmari N, Maslovskaja J, Kisand K, Peterson P, Irla M, Giraud M. EMBO Rep. 2022 Feb 3;23(3):e53576. doi: 10.15252/embr.202153576. Epub 2022 Jan 17. PubMed
Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway. Wang B, Zhang J, Liu X, Chai Q, Lu X, Yao X, Yang Z, Sun L, Johnson SF, Schwartz RC, Zheng YH. Autophagy. 2022 Feb 7:1-18. doi: 10.1080/15548627.2022.2031381. PubMed
The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2. Helsen C, Nguyen T, Vercruysse T, Wouters S, Daelemans D, Voet A, Claessens F. Int J Mol Sci. 2022 Jan 29;23(3). pii: ijms23031557. doi: 10.3390/ijms23031557. PubMed
A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis. Zhu L, Retana D, Garcia-Gomez P, Alvaro-Espinosa L, Priego N, Masmudi-Martin M, Yebra N, Miarka L, Hernandez-Encinas E, Blanco-Aparicio C, Martinez S, Sobrino C, Ajenjo N, Artiga MJ, Ortega-Paino E, Torres-Ruiz R, Rodriguez-Perales S, Soffietti R, Bertero L, Cassoni P, Weiss T, Munoz J, Sepulveda JM, Gonzalez-Leon P, Jimenez-Roldan L, Moreno LM, Esteban O, Perez-Nunez A, Hernandez-Lain A, Toldos O, Ruano Y, Alcazar L, Blasco G, Fernandez-Alen J, Caleiras E, Lafarga M, Megias D, Grana-Castro O, Nor C, Taylor MD, Young LS, Vareslija D, Cosgrove N, Couch FJ, Cusso L, Desco M, Mouron S, Quintela-Fandino M, Weller M, Pastor J, Valiente M. EMBO Mol Med. 2022 Mar 7;14(3):e14552. doi: 10.15252/emmm.202114552. Epub 2022 Feb 17. PubMed
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers. Giles JR, Manne S, Freilich E, Oldridge DA, Baxter AE, George S, Chen Z, Huang H, Chilukuri L, Carberry M, Giles L, Weng NP, Young RM, June CH, Schuchter LM, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Huang AC, Shi J, Wherry EJ. Immunity. 2022 Mar 8;55(3):557-574.e7. doi: 10.1016/j.immuni.2022.02.004. PubMed Associated Plasmids pED9x (dCas9-KRAB-mCherry)
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2. Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok NS, Wang X, Fu X, Patel A, Sundaram R, Tebaldi T, Mamillapalli P, Zeidan AM, Flavell RA, Prebet T, Bindra RS, Halene S. Leukemia. 2022 May;36(5):1313-1323. doi: 10.1038/s41375-022-01536-x. Epub 2022 Mar 10. PubMed
Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies. Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, Courchaine E, Barentine AES, Machyna M, Botti V, Qin A, Gbyli R, Patel A, Song Y, Kiefer L, Viero G, Neuenkirchen N, Lin H, Bewersdorf J, Simon MD, Neugebauer KM, Tebaldi T, Halene S. Mol Cell. 2022 Mar 17;82(6):1107-1122.e7. doi: 10.1016/j.molcel.2022.02.025. PubMed
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition. Gallo D, Young JTF, Fourtounis J, Martino G, Alvarez-Quilon A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugere-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkac J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D. Nature. 2022 Apr;604(7907):749-756. doi: 10.1038/s41586-022-04638-9. Epub 2022 Apr 20. PubMed
5'isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1. Li X, Michels BE, Tosun OE, Jung J, Kappes J, Ibing S, Nataraj NB, Sahay S, Schneider M, Worner A, Becki C, Ishaque N, Feuerbach L, Hessling B, Helm D, Will R, Yarden Y, Muller-Decker K, Wiemann S, Korner C. J Exp Clin Cancer Res. 2022 Jun 2;41(1):190. doi: 10.1186/s13046-022-02380-8. PubMed
Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model. Yamaguchi K, Yoshihiro T, Ariyama H, Ito M, Nakano M, Semba Y, Nogami J, Tsuchihashi K, Yamauchi T, Ueno S, Isobe T, Shindo K, Moriyama T, Ohuchida K, Nakamura M, Nagao Y, Ikeda T, Hashizume M, Konomi H, Torisu T, Kitazono T, Kanayama T, Tomita H, Oda Y, Kusaba H, Maeda T, Akashi K, Baba E. Gastric Cancer. 2022 Sep;25(5):862-878. doi: 10.1007/s10120-022-01307-8. Epub 2022 Jun 4. PubMed
Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen. Pedersen SF, Collora JA, Kim RN, Yang K, Razmi A, Catalano AA, Yeh YJ, Mounzer K, Tebas P, Montaner LJ, Ho YC. J Virol. 2022 Jul 13;96(13):e0057722. doi: 10.1128/jvi.00577-22. Epub 2022 Jun 22. PubMed
Sculpting Rupture-Free Nuclear Shapes in Fibrous Environments. Jana A, Tran A, Gill A, Kiepas A, Kapania RK, Konstantopoulos K, Nain AS. Adv Sci (Weinh). 2022 Sep;9(25):e2203011. doi: 10.1002/advs.202203011. Epub 2022 Jul 21. PubMed
Enhanced efficiency of generating human-induced pluripotent stem cells using Lin28-30Kc19 fusion protein. Son B, Yoon H, Ryu J, Lee H, Joo J, Park HH, Park TH. Front Bioeng Biotechnol. 2022 Jul 22;10:911614. doi: 10.3389/fbioe.2022.911614. eCollection 2022. PubMed
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma. Shi DD, Savani MR, Levitt MM, Wang AC, Endress JE, Bird CE, Buehler J, Stopka SA, Regan MS, Lin YF, Puliyappadamba VT, Gao W, Khanal J, Evans L, Lee JH, Guo L, Xiao Y, Xu M, Huang B, Jennings RB, Bonal DM, Martin-Sandoval MS, Dang T, Gattie LC, Cameron AB, Lee S, Asara JM, Kornblum HI, Mak TW, Looper RE, Nguyen QD, Signoretti S, Gradl S, Sutter A, Jeffers M, Janzer A, Lehrman MA, Zacharias LG, Mathews TP, Losman JA, Richardson TE, Cahill DP, DeBerardinis RJ, Ligon KL, Xu L, Ly P, Agar NYR, Abdullah KG, Harris IS, Kaelin WG Jr, McBrayer SK. Cancer Cell. 2022 Sep 12;40(9):939-956.e16. doi: 10.1016/j.ccell.2022.07.011. Epub 2022 Aug 18. PubMed Associated Plasmids pMSCV-MerCreMer-hygro pAAV2-sgTrp53-sgAtrx-EFS-Cre pLBCX-Large-T-antigenK1 mutant
BCG-Induced Tumor Immunity Requires Tumor-Intrinsic CIITA Independent of MHC-II. Redelman-Sidi G, Binyamin A, Antonelli AC, Catalano W, Bean J, Al-Ahmadie H, Jungbluth AA, Glickman MS. Cancer Immunol Res. 2022 Oct 4;10(10):1241-1253. doi: 10.1158/2326-6066.CIR-22-0157. PubMed
Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors. Ma L, Mei Y, Xu P, Cheng Y, You Z, Ji X, Zhuang D, Zhou W, Chen Y, Xiong M. iScience. 2022 Sep 20;25(10):105172. doi: 10.1016/j.isci.2022.105172. eCollection 2022 Oct 21. PubMed
The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma. Paris A, Tardif N, Baietti FM, Berra C, Leclair HM, Leucci E, Galibert MD, Corre S. EMBO Mol Med. 2022 Dec 7;14(12):e15677. doi: 10.15252/emmm.202215677. Epub 2022 Oct 28. PubMed
VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection. Li X, Anderson DE, Chang YY, Jarnik M, Machner MP. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2209149119. doi: 10.1073/pnas.2209149119. Epub 2022 Nov 21. PubMed
Systematic generation and imaging of tandem repeats reveal base-pairing properties that promote RNA aggregation. Isiktas AU, Eshov A, Yang S, Guo JU. Cell Rep Methods. 2022 Nov 9;2(11):100334. doi: 10.1016/j.crmeth.2022.100334. eCollection 2022 Nov 21. PubMed
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins. Li J, Chen CH, O'Neill KL, Fousek-Schuller VJ, Black AR, Black JD, Zhang J, Luo X. J Biol Chem. 2023 Feb;299(2):102875. doi: 10.1016/j.jbc.2023.102875. Epub 2023 Jan 6. PubMed
NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation. Zhang F, Wang Y, Zhao Y, Wang M, Zhou B, Zhou B, Ge X. Elife. 2023 Feb 15;12:e81569. doi: 10.7554/eLife.81569. PubMed
Mapping of clonal lineages across developmental stages in human neural differentiation. You Z, Wang L, He H, Wu Z, Zhang X, Xue S, Xu P, Hong Y, Xiong M, Wei W, Chen Y. Cell Stem Cell. 2023 Apr 6;30(4):473-487.e9. doi: 10.1016/j.stem.2023.02.007. Epub 2023 Mar 17. PubMed Associated Plasmids FGF8-P2A-iCre APCDD1-P2A-tdTomato Pdest-EF1α-EGFP-32bp barcode polyA library
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