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gag/pol Citations (75)

Originally described in: A role for Wnt signalling in self-renewal of haematopoietic stem cells.
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL Nature. 2003 May 22. 423(6938):409-14.
PubMed Journal

Articles Citing gag/pol

Articles
Induced pluripotent stem cells from highly endangered species. Ben-Nun IF, Montague SC, Houck ML, Tran HT, Garitaonandia I, Leonardo TR, Wang YC, Charter SJ, Laurent LC, Ryder OA, Loring JF. Nat Methods. 2011 Sep 4;8(10):829-31. doi: 10.1038/nmeth.1706. PubMed
Development of hematopoietic stem and progenitor cells from mouse embryonic stem cells, in vitro, supported by ectopic human HOXB4 expression. Pilat S, Carotta S, Klump H. Methods Mol Biol. 2013;1029:129-47. doi: 10.1007/978-1-62703-478-4_10. PubMed
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016/j.cell.2013.11.037. PubMed
Generation and Neuronal Differentiation of Patient-Specific Induced Pluripotent Stem Cells Derived from Niemann-Pick Type C1 Fibroblasts. Trilck M, Hubner R, Frech MJ. Methods Mol Biol. 2014 Dec 18. PubMed
Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. Mauger O, Klinck R, Chabot B, Muchardt C, Allemand E, Batsche E. Nucleic Acids Res. 2015 Feb 18;43(3):1869-82. doi: 10.1093/nar/gkv013. Epub 2015 Jan 20. PubMed
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Gallego Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, Banovich NE, Kagan CL, Burnett JE, Huang CH, Mitrano A, Chavarria CI, Friedrich Ben-Nun I, Li Y, Sabatini K, Leonardo TR, Parast M, Marques-Bonet T, Laurent LC, Loring JF, Gilad Y. Elife. 2015 Jun 23;4:e07103. doi: 10.7554/eLife.07103. PubMed
Generation of Induced Pluripotent Stem Cells from Mammalian Endangered Species. Friedrich Ben-Nun I, Montague SC, Houck ML, Ryder O, Loring JF. Methods Mol Biol. 2015;1330:101-9. doi: 10.1007/978-1-4939-2848-4_10. PubMed
Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks. Zhuo JM, Tseng HA, Desai M, Bucklin ME, Mohammed AI, Robinson NT, Boyden ES, Rangel LM, Jasanoff AP, Gritton HJ, Han X. Elife. 2016 Dec 3;5. pii: e22429. doi: 10.7554/eLife.22429. PubMed

Associated Plasmids

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming. Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Rodriguez Esteban C, Nunez G, Nunez Delicado E, Campistol JM, Guillen I, Guillen P, Izpisua Belmonte JC. Cell. 2016 Dec 15;167(7):1719-1733.e12. doi: 10.1016/j.cell.2016.11.052. PubMed
Observation of Parkin-Mediated Mitophagy in Pancreatic beta-Cells. Hoshino A, Matoba S. Methods Mol Biol. 2017 May 3. doi: 10.1007/7651_2017_39. PubMed
Ubiquitination of exposed glycoproteins by SCF(FBXO27) directs damaged lysosomes for autophagy. Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, Iwai K, Saeki Y, Yoshimori T, Matsuda N, Tanaka K. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8574-8579. doi: 10.1073/pnas.1702615114. Epub 2017 Jul 25. PubMed
Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1 Hurwitz SN, Cheerathodi MR, Nkosi D, York SB, Meckes DG Jr. J Virol. 2018 Feb 12;92(5). pii: JVI.01969-17. doi: 10.1128/JVI.01969-17. Print 2018 Mar 1. PubMed
A Rapid and Precise Mutation-Activated Fluorescence Reporter for Analyzing Acute Mutagenesis Frequency. Birnbaum MD, Nemzow L, Kumar A, Gong F, Zhang F. Cell Chem Biol. 2018 Aug 16;25(8):1038-1049.e5. doi: 10.1016/j.chembiol.2018.05.010. Epub 2018 Jun 14. PubMed

Associated Plasmids

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. Riley JS, Quarato G, Cloix C, Lopez J, O'Prey J, Pearson M, Chapman J, Sesaki H, Carlin LM, Passos JF, Wheeler AP, Oberst A, Ryan KM, Tait SW. EMBO J. 2018 Sep 3;37(17). pii: embj.201899238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26. PubMed

Associated Plasmids

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence. Kim YY, Um JH, Yun J. J Vis Exp. 2018 Aug 12;(138). doi: 10.3791/57890. PubMed
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr. Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13. PubMed
IDH1 mutation correlates with a beneficial prognosis and suppresses tumor growth in IHCC. Wang J, Zhang ZG, Ding ZY, Dong W, Liang HF, Chu L, Zhang BX, Chen XP. J Surg Res. 2018 Nov;231:116-125. doi: 10.1016/j.jss.2018.04.056. Epub 2018 Jun 17. PubMed
The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Bainor AJ, Saini S, Calderon A, Casado-Polanco R, Giner-Ramirez B, Moncada C, Cantor DJ, Ernlund A, Litovchick L, David G. Cell Rep. 2018 Dec 4;25(10):2797-2807.e8. doi: 10.1016/j.celrep.2018.11.024. PubMed
FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. Yan P, Li Q, Wang L, Lu P, Suzuki K, Liu Z, Lei J, Li W, He X, Wang S, Ding J, Chan P, Zhang W, Song M, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Cell Stem Cell. 2019 Mar 7;24(3):447-461.e8. doi: 10.1016/j.stem.2018.12.002. Epub 2019 Jan 17. PubMed
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias. Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, Gutierrez A. Cancer Cell. 2019 Apr 15;35(4):664-676.e7. doi: 10.1016/j.ccell.2019.03.004. PubMed
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Gomes AP, Ilter D, Low V, Rosenzweig A, Shen ZJ, Schild T, Rivas MA, Er EE, McNally DR, Mutvei AP, Han J, Ou YH, Cavaliere P, Mullarky E, Nagiec M, Shin S, Yoon SO, Dephoure N, Massague J, Melnick AM, Cantley LC, Tyler JK, Blenis J. Cancer Cell. 2019 Oct 14;36(4):402-417.e13. doi: 10.1016/j.ccell.2019.08.006. Epub 2019 Sep 26. PubMed
The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Hoshino A, Wang WJ, Wada S, McDermott-Roe C, Evans CS, Gosis B, Morley MP, Rathi KS, Li J, Li K, Yang S, McManus MJ, Bowman C, Potluri P, Levin M, Damrauer S, Wallace DC, Holzbaur ELF, Arany Z. Nature. 2019 Nov;575(7782):375-379. doi: 10.1038/s41586-019-1667-4. Epub 2019 Oct 16. PubMed
pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate. Jia X, Pan L, Zhu M, Hu H, Zhai L, Liu J, Hu M, Liu B, Tan M. J Proteomics. 2020 Jan 6;210:103545. doi: 10.1016/j.jprot.2019.103545. Epub 2019 Oct 15. PubMed
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification. Cross SH, Mckie L, Hurd TW, Riley S, Wills J, Barnard AR, Young F, MacLaren RE, Jackson IJ. PLoS Genet. 2020 Apr 1;16(4):e1008583. doi: 10.1371/journal.pgen.1008583. eCollection 2020 Apr. PubMed
Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter. Xiao Y, Lamar JM. J Vis Exp. 2020 Mar 27;(157). doi: 10.3791/60582. PubMed
A homozygous variant in NDUFA8 is associated with developmental delay, microcephaly, and epilepsy due to mitochondrial complex I deficiency. Yatsuka Y, Kishita Y, Formosa LE, Shimura M, Nozaki F, Fujii T, Nitta KR, Ohtake A, Murayama K, Ryan MT, Okazaki Y. Clin Genet. 2020 Aug;98(2):155-165. doi: 10.1111/cge.13773. Epub 2020 May 25. PubMed
Heme oxygenase promotes B-Raf-dependent melanosphere formation. Jasmer KJ, Hou J, Mannino P, Cheng J, Hannink M. Pigment Cell Melanoma Res. 2020 Jun 17. doi: 10.1111/pcmr.12905. PubMed
Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR. Yan W, Markegard E, Dharmaiah S, Urisman A, Drew M, Esposito D, Scheffzek K, Nissley DV, McCormick F, Simanshu DK. Cell Rep. 2020 Jul 21;32(3):107909. doi: 10.1016/j.celrep.2020.107909. PubMed

Associated Plasmids

The aryl hydrocarbon receptor promotes inflammation-induced dedifferentiation and systemic metastatic spread of melanoma cells. Mengoni M, Braun AD, Gaffal E, Tuting T. Int J Cancer. 2020 Nov 15;147(10):2902-2913. doi: 10.1002/ijc.33252. Epub 2020 Aug 31. PubMed
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Koessinger AL, Koessinger D, Stevenson K, Cloix C, Mitchell L, Nixon C, Gomez-Roman N, Chalmers AJ, Norman JC, Tait SWG. Sci Rep. 2020 Sep 21;10(1):15361. doi: 10.1038/s41598-020-72322-x. PubMed
Protocol to Reprogram Human Menstrual Blood-Derived Stromal Cells to Generate AOX15-iPSCs. Sanzhez-Mata A, Ferez-Gomez A, Gonzalez-Munoz E. STAR Protoc. 2020 Nov 25;1(3):100183. doi: 10.1016/j.xpro.2020.100183. eCollection 2020 Dec 18. PubMed
Transcriptional regulation of VEGFA expression in T-regulatory cells from breast cancer patients. Kajal K, Bose S, Panda AK, Chakraborty D, Chakraborty S, Pati S, Sarkar T, Dhar S, Roy D, Saha S, Sa G. Cancer Immunol Immunother. 2021 Jul;70(7):1877-1891. doi: 10.1007/s00262-020-02808-0. Epub 2021 Jan 4. PubMed
Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging. Deng P, Yuan Q, Cheng Y, Li J, Liu Z, Liu Y, Li Y, Su T, Wang J, Salvo ME, Wang W, Fan G, Lyons K, Yu B, Wang CY. Cell Stem Cell. 2021 Jun 3;28(6):1057-1073.e7. doi: 10.1016/j.stem.2021.01.010. Epub 2021 Feb 10. PubMed
CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms. Batsche E, Yi J, Mauger O, Kornobis E, Hopkins B, Hanmer-Lloyd C, Muchardt C. Nucleic Acids Res. 2021 Jun 21;49(11):6213-6237. doi: 10.1093/nar/gkab437. PubMed
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified. Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, Jacobs K, Broux M, Verhoef G, Michaux L, Graux C, Wlodarska I, Gaulard P, de Leval L, Tousseyn T, Cools J, Dierickx D. Nat Commun. 2021 Jun 17;12(1):3705. doi: 10.1038/s41467-021-24037-4. PubMed
YAP inactivation in estrogen receptor alpha-positive hepatocellular carcinoma with less aggressive behavior. Jeon Y, Yoo JE, Rhee H, Kim YJ, Il Kim G, Chung T, Yoon S, Shin B, Woo HG, Park YN. Exp Mol Med. 2021 Jun;53(6):1055-1067. doi: 10.1038/s12276-021-00639-2. Epub 2021 Jun 18. PubMed
Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase. Yoshida Y, Asahina M, Murakami A, Kawawaki J, Yoshida M, Fujinawa R, Iwai K, Tozawa R, Matsuda N, Tanaka K, Suzuki T. Proc Natl Acad Sci U S A. 2021 Jul 6;118(27). pii: 2102902118. doi: 10.1073/pnas.2102902118. PubMed
Tumor cell intrinsic Toll-like receptor 4 signaling promotes melanoma progression and metastatic dissemination. Rogava M, Braun AD, van der Sluis TC, Shridhar N, Tuting T, Gaffal E. Int J Cancer. 2022 Jan 1;150(1):142-151. doi: 10.1002/ijc.33804. Epub 2021 Sep 29. PubMed
Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro. Eisele BS, Luka Z, Wu AJ, Yang F, Hale AT, York JD. J Biol Chem. 2021 Nov;297(5):101293. doi: 10.1016/j.jbc.2021.101293. Epub 2021 Oct 8. PubMed
Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nguyen NT, Huang K, Zeng H, Jing J, Wang R, Fang S, Chen J, Liu X, Huang Z, You MJ, Rao A, Huang Y, Han G, Zhou Y. Nat Nanotechnol. 2021 Dec;16(12):1424-1434. doi: 10.1038/s41565-021-00982-5. Epub 2021 Oct 25. PubMed
GCN2 adapts protein synthesis to scavenging-dependent growth. Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wuhr M, Sabatini DM, Rabinowitz JD. Cell Syst. 2022 Feb 16;13(2):158-172.e9. doi: 10.1016/j.cels.2021.09.014. Epub 2021 Oct 26. PubMed
Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Bock FJ, Sedov E, Koren E, Koessinger AL, Cloix C, Zerbst D, Athineos D, Anand J, Campbell KJ, Blyth K, Fuchs Y, Tait SWG. Nat Commun. 2021 Nov 12;12(1):6572. doi: 10.1038/s41467-021-26613-0. PubMed
Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium. Padonou F, Gonzalez V, Provin N, Yayilkan S, Jmari N, Maslovskaja J, Kisand K, Peterson P, Irla M, Giraud M. EMBO Rep. 2022 Feb 3;23(3):e53576. doi: 10.15252/embr.202153576. Epub 2022 Jan 17. PubMed
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Rogers TF, Wilson IA, Burton DR, Andrabi R. Sci Transl Med. 2022 Mar 23;14(637):eabi9215. doi: 10.1126/scitranslmed.abi9215. Epub 2022 Mar 23. PubMed
DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6. Zhang X, Hu Y, Pan Y, Xiong Y, Zhang Y, Han M, Dong K, Song J, Liang H, Ding Z, Zhang X, Zhu H, Liu Q, Lu X, Feng Y, Chen X, Zhang Z, Zhang B. Oncogene. 2022 Mar;41(12):1821-1834. doi: 10.1038/s41388-022-02212-1. Epub 2022 Feb 9. PubMed
Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Cao K, Riley JS, Heilig R, Montes-Gomez AE, Vringer E, Berthenet K, Cloix C, Elmasry Y, Spiller DG, Ichim G, Campbell KJ, Gilmore AP, Tait SWG. Dev Cell. 2022 May 23;57(10):1211-1225.e6. doi: 10.1016/j.devcel.2022.03.019. Epub 2022 Apr 20. PubMed
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Koessinger AL, Cloix C, Koessinger D, Heiland DH, Bock FJ, Strathdee K, Kinch K, Martinez-Escardo L, Paul NR, Nixon C, Malviya G, Jackson MR, Campbell KJ, Stevenson K, Davis S, Elmasry Y, Ahmed A, O'Prey J, Ichim G, Schnell O, Stewart W, Blyth K, Ryan KM, Chalmers AJ, Norman JC, Tait SWG. Cell Death Differ. 2022 Apr 26. pii: 10.1038/s41418-022-01001-3. doi: 10.1038/s41418-022-01001-3. PubMed
A broad and potent neutralization epitope in SARS-related coronaviruses. Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, Schief WR, Nemazee D, Walker LM, Andrabi R, Burton DR, Wilson IA. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2205784119. doi: 10.1073/pnas.2205784119. Epub 2022 Jun 29. PubMed
FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation. Dibus N, Zobalova E, Monleon MAM, Korinek V, Filipp D, Petrusova J, Sedlacek R, Kasparek P, Cermak L. Front Cell Dev Biol. 2022 Jun 13;10:914053. doi: 10.3389/fcell.2022.914053. eCollection 2022. PubMed
FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability. Dibus N, Korinek V, Cermak L. Front Cell Dev Biol. 2022 Jun 23;10:929288. doi: 10.3389/fcell.2022.929288. eCollection 2022. PubMed
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Zhao F, Keating C, Ozorowski G, Shaabani N, Francino-Urdaniz IM, Barman S, Limbo O, Burns A, Zhou P, Ricciardi MJ, Woehl J, Tran Q, Turner HL, Peng L, Huang D, Nemazee D, Andrabi R, Sok D, Teijaro JR, Whitehead TA, Ward AB, Burton DR, Jardine JG. iScience. 2022 Sep 16;25(9):104914. doi: 10.1016/j.isci.2022.104914. Epub 2022 Aug 11. PubMed
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma. Shi DD, Savani MR, Levitt MM, Wang AC, Endress JE, Bird CE, Buehler J, Stopka SA, Regan MS, Lin YF, Puliyappadamba VT, Gao W, Khanal J, Evans L, Lee JH, Guo L, Xiao Y, Xu M, Huang B, Jennings RB, Bonal DM, Martin-Sandoval MS, Dang T, Gattie LC, Cameron AB, Lee S, Asara JM, Kornblum HI, Mak TW, Looper RE, Nguyen QD, Signoretti S, Gradl S, Sutter A, Jeffers M, Janzer A, Lehrman MA, Zacharias LG, Mathews TP, Losman JA, Richardson TE, Cahill DP, DeBerardinis RJ, Ligon KL, Xu L, Ly P, Agar NYR, Abdullah KG, Harris IS, Kaelin WG Jr, McBrayer SK. Cancer Cell. 2022 Sep 12;40(9):939-956.e16. doi: 10.1016/j.ccell.2022.07.011. Epub 2022 Aug 18. PubMed

Associated Plasmids

UBE2T promotes glioblastoma malignancy through ubiquitination-mediated degradation of RPL6. Tao X, Wu X, Zhou P, Yu X, Zhao C, Peng X, Zhang K, Shen L, Peng J, Yang L. Cancer Sci. 2023 Feb;114(2):521-532. doi: 10.1111/cas.15604. Epub 2022 Oct 14. PubMed
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration. Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT. iScience. 2022 Sep 2;25(10):105050. doi: 10.1016/j.isci.2022.105050. eCollection 2022 Oct 21. PubMed
ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth. Park J, Park GY, Lee J, Park J, Kim S, Kim E, Park SY, Yoon JH, Lee Y. Front Mol Biosci. 2022 Dec 22;9:1030725. doi: 10.3389/fmolb.2022.1030725. eCollection 2022. PubMed
NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation. Zhang F, Wang Y, Zhao Y, Wang M, Zhou B, Zhou B, Ge X. Elife. 2023 Feb 15;12:e81569. doi: 10.7554/eLife.81569. PubMed
Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins. Fricke T, Schlagowski S, Liu S, Yang X, Fiebig U, Kaul A, Ensser A, Hahn AS. Viruses. 2023 Jan 17;15(2):262. doi: 10.3390/v15020262. PubMed
Mapping of clonal lineages across developmental stages in human neural differentiation. You Z, Wang L, He H, Wu Z, Zhang X, Xue S, Xu P, Hong Y, Xiong M, Wei W, Chen Y. Cell Stem Cell. 2023 Apr 6;30(4):473-487.e9. doi: 10.1016/j.stem.2023.02.007. Epub 2023 Mar 17. PubMed

Associated Plasmids

Collagen I-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression. Xiong YX, Zhang XC, Zhu JH, Zhang YX, Pan YL, Wu Y, Zhao JP, Liu JJ, Lu YX, Liang HF, Zhang ZG, Zhang WG. Cell Death Differ. 2023 Jul;30(7):1648-1665. doi: 10.1038/s41418-023-01166-5. Epub 2023 Apr 28. PubMed
Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion. Minami Y, Hoshino A, Higuchi Y, Hamaguchi M, Kaneko Y, Kirita Y, Taminishi S, Nishiji T, Taruno A, Fukui M, Arany Z, Matoba S. Nat Commun. 2023 Jul 13;14(1):4084. doi: 10.1038/s41467-023-39404-6. PubMed

Associated Plasmids

Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P. Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, Hong WB, Zhou B, Chen QT, Wu Q. Cell Res. 2023 Jul 17. doi: 10.1038/s41422-023-00848-6. PubMed
NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages. Rojas-Lopez M, Gil-Marques ML, Kharbanda V, Zajac AS, Miller KA, Wood TE, Hachey AC, Egger KT, Goldberg MB. Sci Immunol. 2023 Jul 21;8(85):eabo4767. doi: 10.1126/sciimmunol.abo4767. Epub 2023 Jul 21. PubMed
Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular Carcinoma. Jeon Y, Kim T, Kwon H, Kim JK, Park YT, Ham J, Kim YJ. Cancers (Basel). 2023 Aug 5;15(15):3987. doi: 10.3390/cancers15153987. PubMed
Interchangeability of the Assays Used to Assess the Activity of Anti-SARS-CoV-2 Monoclonal Antibodies. Hickerson BT, Khalenkov AM, Xie T, Frucht DM, Scott DE, Ilyushina NA. Viruses. 2023 Aug 5;15(8):1698. doi: 10.3390/v15081698. PubMed
Cholesterol biogenesis is a PTEN-dependent actionable node for the treatment of endocrine therapy-refractory cancers. Kaysudu I, Gungul TB, Atici S, Yilmaz S, Bayram E, Guven G, Cizmecioglu NT, Sahin O, Yesiloz G, Haznedaroglu BZ, Cizmecioglu O. Cancer Sci. 2023 Nov;114(11):4365-4375. doi: 10.1111/cas.15960. Epub 2023 Sep 14. PubMed
An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing. Pan H, Cheng X, Rodriguez PFG, Zhang X, Chung I, Jin VX, Li W, Hu Y, Li R. J Biol Chem. 2023 Nov;299(11):105259. doi: 10.1016/j.jbc.2023.105259. Epub 2023 Sep 17. PubMed
The Antiviral Factor SERINC5 Impairs the Expression of Non-Self-DNA. Shi Y, Simpson S, Ahmed SK, Chen Y, Tavakoli-Tameh A, Janaka SK, Evans DT, Serra-Moreno R. Viruses. 2023 Sep 20;15(9):1961. doi: 10.3390/v15091961. PubMed
CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity. Zhang G, Jiang P, Tang W, Wang Y, Qiu F, An J, Zheng Y, Wu D, Zhou J, Neculai D, Shi Y, Sheng W. Mol Cell. 2023 Dec 7;83(23):4370-4385.e9. doi: 10.1016/j.molcel.2023.10.043. Epub 2023 Nov 27. PubMed
Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-kappaB-mediated inflammatory response. Vringer E, Heilig R, Riley JS, Black A, Cloix C, Skalka G, Montes-Gomez AE, Aguado A, Lilla S, Walczak H, Gyrd-Hansen M, Murphy DJ, Huang DT, Zanivan S, Tait SW. EMBO J. 2024 Mar;43(6):904-930. doi: 10.1038/s44318-024-00044-1. Epub 2024 Feb 9. PubMed
Efficient and scalable gene delivery method with easily generated cationic carbon dots. Algarra M, Gonzalez-Munoz E. Biol Proced Online. 2024 Mar 8;26(1):6. doi: 10.1186/s12575-024-00232-7. PubMed
Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1. Wright T, Turnis ME, Grace CR, Li X, Brakefield LA, Wang YD, Xu H, Kaminska E, Climer LK, Mukiza TO, Chang CL, Moldoveanu T, Opferman JT. Mol Cell. 2024 Apr 4;84(7):1338-1353.e8. doi: 10.1016/j.molcel.2024.02.035. Epub 2024 Mar 18. PubMed
Mutant FOXO1 controls an oncogenic network via enhancer accessibility. Layden HM, Ellis JD, Bomber ML, Bartlett LN, Hiebert SW, Stengel KR. Cell Genom. 2024 Apr 10;4(4):100537. doi: 10.1016/j.xgen.2024.100537. PubMed
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome. Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H. Cell Rep. 2024 Apr 23;43(4):114111. doi: 10.1016/j.celrep.2024.114111. Epub 2024 Apr 12. PubMed
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