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FUGW Citations (211)

Originally described in: Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors.
Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D Science. 2002 Feb 1. 295(5556):868-72. PubMed Journal

Articles Citing FUGW

Articles
Somatic coding mutations in human induced pluripotent stem cells. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. PubMed
Non-viral gene delivery nanoparticles based on poly(beta-amino esters) for treatment of glioblastoma. Tzeng SY, Guerrero-Cazares H, Martinez EE, Sunshine JC, Quinones-Hinojosa A, Green JJ. Biomaterials. 2011 Aug;32(23):5402-10. doi: 10.1016/j.biomaterials.2011.04.016. Epub 2011 May 4. PubMed
Transduction of human cells with polymer-complexed ecotropic lentivirus for enhanced biosafety. Barrilleaux B, Knoepfler P. J Vis Exp. 2011 Jul 24;(53). pii: 2822. doi: 10.3791/2822. PubMed
Nanotopography as modulator of human mesenchymal stem cell function. Kulangara K, Yang Y, Yang J, Leong KW. Biomaterials. 2012 Jul;33(20):4998-5003. doi: 10.1016/j.biomaterials.2012.03.053. Epub 2012 Apr 18. PubMed
Genetic background affects induced pluripotent stem cell generation. Schnabel LV, Abratte CM, Schimenti JC, Southard TL, Fortier LA. Stem Cell Res Ther. 2012 Aug 3;3(4):30. doi: 10.1186/scrt121. PubMed
Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. Peters EB, Christoforou N, Leong KW, Truskey GA. Tissue Eng Part A. 2013 Mar;19(5-6):697-706. doi: 10.1089/ten.tea.2011.0704. Epub 2012 Nov 21. PubMed
Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW. PLoS One. 2013 May 21;8(5):e63577. doi: 10.1371/journal.pone.0063577. Print 2013. PubMed
Neuropathic and inflammatory pain are modulated by tuberoinfundibular peptide of 39 residues. Dimitrov EL, Kuo J, Kohno K, Usdin TB. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13156-61. doi: 10.1073/pnas.1306342110. Epub 2013 Jul 22. PubMed
Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small SA, Kandel ER. Sci Transl Med. 2013 Aug 28;5(200):200ra115. doi: 10.1126/scitranslmed.3006373. PubMed
Noninvasive visualization of tumor growth in a human colorectal liver metastases xenograft model using bioluminescence in vivo imaging. Thalheimer A, Korb D, Bonicke L, Wiegering A, Muhling B, Schneider M, Koch S, Riedel SS, Germer CT, Beilhack A, Brandlein S, Otto C. J Surg Res. 2013 Nov;185(1):143-51. doi: 10.1016/j.jss.2013.03.024. Epub 2013 Mar 30. PubMed
Increased expression of reticulon 3 in neurons leads to reduced axonal transport of beta site amyloid precursor protein-cleaving enzyme 1. Deng M, He W, Tan Y, Han H, Hu X, Xia K, Zhang Z, Yan R. J Biol Chem. 2013 Oct 18;288(42):30236-45. doi: 10.1074/jbc.M113.480079. Epub 2013 Sep 4. PubMed
Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease. Datta A, Alexander R, Sulikowski MG, Nicholson AG, Maher TM, Scotton CJ, Chambers RC. J Immunol. 2013 Nov 1;191(9):4867-79. doi: 10.4049/jimmunol.1300588. Epub 2013 Sep 30. PubMed
Thalamic neuropeptide mediating the effects of nursing on lactation and maternal motivation. Cservenak M, Szabo ER, Bodnar I, Leko A, Palkovits M, Nagy GM, Usdin TB, Dobolyi A. Psychoneuroendocrinology. 2013 Dec;38(12):3070-84. doi: 10.1016/j.psyneuen.2013.09.004. Epub 2013 Sep 14. PubMed
Long-term neuroprotective effects of NT-4-engineered mesenchymal stem cells injected intravitreally in a mouse model of acute retinal injury. Machalinska A, Kawa M, Pius-Sadowska E, Stepniewski J, Nowak W, Roginska D, Kaczynska K, Baumert B, Wiszniewska B, Jozkowicz A, Dulak J, Machalinski B. Invest Ophthalmol Vis Sci. 2013 Dec 23;54(13):8292-305. doi: 10.1167/iovs.13-12221. PubMed
Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter. Leoh LS, Morizono K, Kershaw KM, Chen IS, Penichet ML, Daniels-Wells TR. J Gene Med. 2014 Jan-Feb;16(1-2):11-27. doi: 10.1002/jgm.2754. PubMed
A novel mechanism for nicotinic potentiation of glutamatergic synapses. Halff AW, Gomez-Varela D, John D, Berg DK. J Neurosci. 2014 Feb 5;34(6):2051-64. doi: 10.1523/JNEUROSCI.2795-13.2014. PubMed
Generation of transgene-free mouse induced pluripotent stem cells using an excisable lentiviral system. Varga E, Nemes C, Davis RP, Ujhelly O, Klincumhom N, Polgar Z, Muenthaisong S, Pirity MK, Dinnyes A. Exp Cell Res. 2014 Apr 1;322(2):335-44. doi: 10.1016/j.yexcr.2014.02.006. Epub 2014 Feb 18. PubMed
STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious. Maycotte P, Gearheart CM, Barnard R, Aryal S, Mulcahy Levy JM, Fosmire SP, Hansen RJ, Morgan MJ, Porter CC, Gustafson DL, Thorburn A. Cancer Res. 2014 May 1;74(9):2579-90. doi: 10.1158/0008-5472.CAN-13-3470. Epub 2014 Mar 3. PubMed
High-content imaging of presynaptic assembly. Poon VY, Goh C, Voorhoeve PM, Fivaz M. Front Cell Neurosci. 2014 Mar 3;8:66. doi: 10.3389/fncel.2014.00066. eCollection 2014. PubMed
Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury. Chen T, Koga K, Descalzi G, Qiu S, Wang J, Zhang LS, Zhang ZJ, He XB, Qin X, Xu FQ, Hu J, Wei F, Huganir RL, Li YQ, Zhuo M. Mol Pain. 2014 Jun 3;10:33. doi: 10.1186/1744-8069-10-33. PubMed
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector. Kabadi AM, Ousterout DG, Hilton IB, Gersbach CA. Nucleic Acids Res. 2014 Aug 13. pii: gku749. PubMed

Associated Plasmids
The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection. Wang Y, Zhou XY, Xiang PY, Wang LL, Tang H, Xie F, Li L, Wei H. PLoS One. 2014 Sep 24;9(9):e108347. doi: 10.1371/journal.pone.0108347. eCollection 2014. PubMed
A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy. Tanida I, Ueno T, Uchiyama Y. PLoS One. 2014 Oct 23;9(10):e110600. doi: 10.1371/journal.pone.0110600. eCollection 2014. PubMed

Associated Plasmids
Establishment of a rabbit Oct4 promoter-based EGFP reporter system. Quan L, Chen Y, Song J, Yan Q, Zhang Q, Lai S, Fan N, Xin J, Zou Q, Lai L. PLoS One. 2014 Oct 31;9(10):e109728. doi: 10.1371/journal.pone.0109728. eCollection 2014. PubMed
A platform for rapid prototyping of synthetic gene networks in mammalian cells. Duportet X, Wroblewska L, Guye P, Li Y, Eyquem J, Rieders J, Rimchala T, Batt G, Weiss R. Nucleic Acids Res. 2014 Dec 1;42(21):13440-51. doi: 10.1093/nar/gku1082. Epub 2014 Nov 5. PubMed
A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification. Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW. Stem Cell Reports. 2014 Dec 9;3(6):940-7. doi: 10.1016/j.stemcr.2014.09.013. Epub 2014 Oct 23. PubMed

Associated Plasmids
Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese. Bi R, Zhang W, Yu D, Li X, Wang HZ, Hu QX, Zhang C, Lu W, Ni J, Fang Y, Li T, Yao YG. Neurobiol Aging. 2015 Mar;36(3):1604.e7-16. doi: 10.1016/j.neurobiolaging.2014.10.009. Epub 2014 Oct 22. PubMed
Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression. Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM. Horm Cancer. 2015 Jun;6(2-3):67-86. doi: 10.1007/s12672-014-0215-9. Epub 2015 Jan 29. PubMed
In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb. Kovalchuk Y, Homma R, Liang Y, Maslyukov A, Hermes M, Thestrup T, Griesbeck O, Ninkovic J, Cohen LB, Garaschuk O. Nat Commun. 2015 Feb 19;6:6349. doi: 10.1038/ncomms7349. PubMed
ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome. Broggini T, Czabanka M, Piffko A, Harms C, Hoffmann C, Mrowka R, Wenke F, Deutsch U, Grotzinger C, Vajkoczy P. Eur Spine J. 2015 Feb 25. PubMed
Induced pluripotent stem cells as a model for diabetes investigation. Stepniewski J, Kachamakova-Trojanowska N, Ogrocki D, Szopa M, Matlok M, Beilharz M, Dyduch G, Malecki MT, Jozkowicz A, Dulak J. Sci Rep. 2015 Feb 26;5:8597. doi: 10.1038/srep08597. PubMed
Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons. Wang S, Wang B, Pan N, Fu L, Wang C, Song G, An J, Liu Z, Zhu W, Guan Y, Xu ZQ, Chan P, Chen Z, Zhang YA. Sci Rep. 2015 Mar 18;5:9232. doi: 10.1038/srep09232. PubMed
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, Cordon-Cardo C, Robinson BD, Trotman LC. Cancer Discov. 2015 Jun;5(6):636-51. doi: 10.1158/2159-8290.CD-14-1113. Epub 2015 Mar 31. PubMed
Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer. Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P. Integr Biol (Camb). 2015 Jun 8;7(6):713-25. doi: 10.1039/c5ib00067j. Epub 2015 May 20. PubMed
Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient. Cereso N, Pequignot MO, Robert L, Becker F, De Luca V, Nabholz N, Rigau V, De Vos J, Hamel CP, Kalatzis V. Mol Ther Methods Clin Dev. 2014 Apr 2;1:14011. doi: 10.1038/mtm.2014.11. eCollection 2014. PubMed
Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior. Bobis-Wozowicz S, Kmiotek K, Sekula M, Kedracka-Krok S, Kamycka E, Adamiak M, Jankowska U, Madetko-Talowska A, Sarna M, Bik-Multanowski M, Kolcz J, Boruczkowski D, Madeja Z, Dawn B, Zuba-Surma EK. Stem Cells. 2015 Jun 1. doi: 10.1002/stem.2078. PubMed
Mitochondrial DNA Haplogroup A Decreases the Risk of Drug Addiction but Conversely Increases the Risk of HIV-1 Infection in Chinese Addicts. Zhang AM, Hu QX, Liu FL, Bi R, Yang BQ, Zhang W, Guo H, Logan I, Zheng YT, Yao YG. Mol Neurobiol. 2015 Jul 11. PubMed
Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Cao W, Liu Y, Zhang R, Zhang B, Wang T, Zhu X, Mei L, Chen H, Zhang H, Ming P, Huang L. Sci Rep. 2015 Jul 13;5:8477. doi: 10.1038/srep08477. PubMed
Apoptotic neurons induce proliferative responses of progenitor cells in the postnatal neocortex. Petrenko V, Mihhailova J, Salmon P, Kiss JZ. Exp Neurol. 2015 Nov;273:126-37. doi: 10.1016/j.expneurol.2015.08.010. Epub 2015 Aug 18. PubMed
CD45+ Cells Present Within Mesenchymal Stem Cell Populations Affect Network Formation of Blood-Derived Endothelial Outgrowth Cells. Peters EB, Christoforou N, Moore E, West JL, Truskey GA. Biores Open Access. 2015 Jan 1;4(1):75-88. doi: 10.1089/biores.2014.0029. eCollection 2015. PubMed
Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts. Kubaczka C, Senner CE, Cierlitza M, Arauzo-Bravo MJ, Kuckenberg P, Peitz M, Hemberger M, Schorle H. Cell Stem Cell. 2015 Sep 22. pii: S1934-5909(15)00360-4. doi: 10.1016/j.stem.2015.08.005. PubMed

Associated Plasmids
p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Tyagi N, Marimuthu S, Bhardwaj A, Deshmukh SK, Srivastava SK, Singh AP, McClellan S, Carter JE, Singh S. Cancer Lett. 2016 Jan 28;370(2):260-7. doi: 10.1016/j.canlet.2015.10.028. Epub 2015 Nov 3. PubMed
MicroRNA miR124 is required for the expression of homeostatic synaptic plasticity. Hou Q, Ruan H, Gilbert J, Wang G, Ma Q, Yao WD, Man HY. Nat Commun. 2015 Dec 1;6:10045. doi: 10.1038/ncomms10045. PubMed
Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model. Wu J, Ryskamp DA, Liang X, Egorova P, Zakharova O, Hung G, Bezprozvanny I. J Neurosci. 2016 Jan 6;36(1):125-41. doi: 10.1523/JNEUROSCI.1038-15.2016. PubMed
Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering. Lai S, Wei S, Zhao B, Ouyang Z, Zhang Q, Fan N, Liu Z, Zhao Y, Yan Q, Zhou X, Li L, Xin J, Zeng Y, Lai L, Zou Q. PLoS One. 2016 Jan 12;11(1):e0146562. doi: 10.1371/journal.pone.0146562. eCollection 2016. PubMed
Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia. Bi R, Tang J, Zhang W, Li X, Chen SY, Yu D, Chen X, Yao YG. Schizophr Res. 2016 Jan 25. pii: S0920-9964(16)30011-1. doi: 10.1016/j.schres.2016.01.011. PubMed
CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes. Evers B, Jastrzebski K, Heijmans JP, Grernrum W, Beijersbergen RL, Bernards R. Nat Biotechnol. 2016 Jun;34(6):631-3. doi: 10.1038/nbt.3536. Epub 2016 Apr 25. PubMed
TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Aizawa S, Okamoto T, Sugiyama Y, Kouwaki T, Ito A, Suzuki T, Ono C, Fukuhara T, Yamamoto M, Okochi M, Hiraga N, Imamura M, Chayama K, Suzuki R, Shoji I, Moriishi K, Moriya K, Koike K, Matsuura Y. Nat Commun. 2016 May 4;7:11379. doi: 10.1038/ncomms11379. PubMed
Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Dou DR, Calvanese V, Sierra MI, Nguyen AT, Minasian A, Saarikoski P, Sasidharan R, Ramirez CM, Zack JA, Crooks GM, Galic Z, Mikkola HK. Nat Cell Biol. 2016 Jun;18(6):595-606. doi: 10.1038/ncb3354. Epub 2016 May 16. PubMed
Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice. Sun F, Zhang ZW, Tan EM, Lim ZL, Li Y, Wang XC, Chua SE, Li J, Cheung E, Yong EL. Carcinogenesis. 2016 Jul;37(7):701-11. doi: 10.1093/carcin/bgw044. Epub 2016 Apr 19. PubMed
Lentiviral transgenesis in mice via a simple method of viral concentration. Cheng PH, Chang YF, Mao SH, Lin HL, Chen CM, Yang SH. Theriogenology. 2016 May 7. pii: S0093-691X(16)30131-5. doi: 10.1016/j.theriogenology.2016.04.088. PubMed
STIM2 regulates AMPA receptor trafficking and plasticity at hippocampal synapses. Yap KA, Shetty MS, Garcia-Alvarez G, Lu B, Alagappan D, Oh-Hora M, Sajikumar S, Fivaz M. Neurobiol Learn Mem. 2016 Aug 18. pii: S1074-7427(16)30150-2. doi: 10.1016/j.nlm.2016.08.007. PubMed
The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus. Narushima M, Uchigashima M, Yagasaki Y, Harada T, Nagumo Y, Uesaka N, Hashimoto K, Aiba A, Watanabe M, Miyata M, Kano M. Neuron. 2016 Sep 7;91(5):1097-1109. doi: 10.1016/j.neuron.2016.07.035. Epub 2016 Aug 18. PubMed
Determinants of effective lentivirus-driven microRNA expression in vivo. Mishima T, Sadovsky E, Gegick ME, Sadovsky Y. Sci Rep. 2016 Sep 15;6:33345. doi: 10.1038/srep33345. PubMed
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD(+) depletion. Sasaki Y, Nakagawa T, Mao X, DiAntonio A, Milbrandt J. Elife. 2016 Oct 13;5. doi: 10.7554/eLife.19749. PubMed
C3 transferase gene therapy for continuous conditional RhoA inhibition. Gutekunst CA, Tung JK, McDougal ME, Gross RE. Neuroscience. 2016 Dec 17;339:308-318. doi: 10.1016/j.neuroscience.2016.10.022. Epub 2016 Oct 13. PubMed

Associated Plasmids
The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease. Ryskamp D, Wu J, Geva M, Kusko R, Grossman I, Hayden M, Bezprozvanny I. Neurobiol Dis. 2017 Jan;97(Pt A):46-59. doi: 10.1016/j.nbd.2016.10.006. Epub 2016 Nov 3. PubMed
The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetii. Latomanski EA, Newton P, Khoo CA, Newton HJ. PLoS Pathog. 2016 Dec 21;12(12):e1006101. doi: 10.1371/journal.ppat.1006101. eCollection 2016 Dec. PubMed
RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts. Gieseler-Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel FH, Fischer T, Handschuh J, Braun-Dullaeus RC, Schrappe M, Lindquist JA, Mertens PR, Thomas U, Brunner-Weinzierl MC. Cell Death Differ. 2016 Dec 23. doi: 10.1038/cdd.2016.141. PubMed
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Abeta Secretion. Huang YA, Zhou B, Wernig M, Sudhof TC. Cell. 2017 Jan 26;168(3):427-441.e21. doi: 10.1016/j.cell.2016.12.044. Epub 2017 Jan 19. PubMed
Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Chuang CH, Greenside PG, Rogers ZN, Brady JJ, Yang D, Ma RK, Caswell DR, Chiou SH, Winters AF, Gruner BM, Ramaswami G, Spencley AL, Kopecky KE, Sayles LC, Sweet-Cordero EA, Li JB, Kundaje A, Winslow MM. Nat Med. 2017 Mar;23(3):291-300. doi: 10.1038/nm.4285. Epub 2017 Feb 13. PubMed
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells. Liu L, Michowski W, Inuzuka H, Shimizu K, Nihira NT, Chick JM, Li N, Geng Y, Meng AY, Ordureau A, Kolodziejczyk A, Ligon KL, Bronson RT, Polyak K, Harper JW, Gygi SP, Wei W, Sicinski P. Nat Cell Biol. 2017 Mar;19(3):177-188. doi: 10.1038/ncb3474. Epub 2017 Feb 13. PubMed
Hypoxia-responsive transgene expression system using RTP801 promoter and synthetic transactivator fused with oxygen-dependent degradation domain. Ono A, Ito A, Sato T, Yamaguchi M, Suzuki T, Kawabe Y, Kamihira M. J Biosci Bioeng. 2017 Jul;124(1):115-124. doi: 10.1016/j.jbiosc.2017.02.012. Epub 2017 Mar 9. PubMed
Polylactide- and polycaprolactone-based substrates enhance angiogenic potential of human umbilical cord-derived mesenchymal stem cells in vitro - implications for cardiovascular repair. Sekula M, Domalik-Pyzik P, Morawska-Chochol A, Bobis-Wozowicz S, Karnas E, Noga S, Boruczkowski D, Adamiak M, Madeja Z, Chlopek J, Zuba-Surma EK. Mater Sci Eng C Mater Biol Appl. 2017 Aug 1;77:521-533. doi: 10.1016/j.msec.2017.03.281. Epub 2017 Mar 30. PubMed
The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models. Hsu JY, Jhang YL, Cheng PH, Chang YF, Mao SH, Yang HI, Lin CW, Chen CM, Yang SH. Front Mol Neurosci. 2017 Jun 20;10:196. doi: 10.3389/fnmol.2017.00196. eCollection 2017. PubMed
miR-196a Enhances Neuronal Morphology through Suppressing RANBP10 to Provide Neuroprotection in Huntington's Disease. Her LS, Mao SH, Chang CY, Cheng PH, Chang YF, Yang HI, Chen CM, Yang SH. Theranostics. 2017 Jun 24;7(9):2452-2462. doi: 10.7150/thno.18813. eCollection 2017. PubMed
Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration. Herrera-Molina R, Mlinac-Jerkovic K, Ilic K, Stober F, Vemula SK, Sandoval M, Milosevic NJ, Simic G, Smalla KH, Goldschmidt J, Bognar SK, Montag D. Sci Rep. 2017 Aug 4;7(1):7273. doi: 10.1038/s41598-017-07839-9. PubMed
Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Dore LC, Jin P, Regot S, Zhuang X, Canzar S, He C, Ming GL, Song H. Cell. 2017 Nov 2;171(4):877-889.e17. doi: 10.1016/j.cell.2017.09.003. Epub 2017 Sep 28. PubMed
Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagan JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA, Jain R. Cell. 2017 Oct 19;171(3):573-587.e14. doi: 10.1016/j.cell.2017.09.018. Epub 2017 Oct 12. PubMed
Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing. Wang K, Jin Q, Ruan D, Yang Y, Liu Q, Wu H, Zhou Z, Ouyang Z, Liu Z, Zhao Y, Zhao B, Zhang Q, Peng J, Lai C, Fan N, Liang Y, Lan T, Li N, Wang X, Wang X, Fan Y, Doevendans PA, Sluijter JPG, Liu P, Li X, Lai L. Genome Res. 2017 Dec;27(12):2061-2071. doi: 10.1101/gr.222521.117. Epub 2017 Nov 16. PubMed
Characterization of SPP inhibitors suppressing propagation of HCV and protozoa. Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10782-E10791. doi: 10.1073/pnas.1712484114. Epub 2017 Nov 29. PubMed
A multi-landing pad DNA integration platform for mammalian cell engineering. Gaidukov L, Wroblewska L, Teague B, Nelson T, Zhang X, Liu Y, Jagtap K, Mamo S, Tseng WA, Lowe A, Das J, Bandara K, Baijuraj S, Summers NM, Lu TK, Zhang L, Weiss R. Nucleic Acids Res. 2018 May 4;46(8):4072-4086. doi: 10.1093/nar/gky216. PubMed
STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle. Morgan EL, Wasson CW, Hanson L, Kealy D, Pentland I, McGuire V, Scarpini C, Coleman N, Arthur JSC, Parish JL, Roberts S, Macdonald A. PLoS Pathog. 2018 Apr 9;14(4):e1006975. doi: 10.1371/journal.ppat.1006975. eCollection 2018 Apr. PubMed
TRPV4 inhibition prevents paclitaxel-induced neurotoxicity in preclinical models. Boehmerle W, Huehnchen P, Lee SLL, Harms C, Endres M. Exp Neurol. 2018 Aug;306:64-75. doi: 10.1016/j.expneurol.2018.04.014. Epub 2018 Apr 30. PubMed
RBM14 is indispensable for pluripotency maintenance and mesoderm development of mouse embryonic stem cells. Chen G, Zhang D, Zhang L, Feng G, Zhang B, Wu Y, Li W, Zhang Y, Hu B. Biochem Biophys Res Commun. 2018 Jun 18;501(1):259-265. doi: 10.1016/j.bbrc.2018.04.231. Epub 2018 May 8. PubMed
Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma. Suryadevara CM, Desai R, Abel ML, Riccione KA, Batich KA, Shen SH, Chongsathidkiet P, Gedeon PC, Elsamadicy AA, Snyder DJ, Herndon JE 2nd, Healy P, Archer GE, Choi BD, Fecci PE, Sampson JH, Sanchez-Perez L. Oncoimmunology. 2018 Feb 21;7(6):e1434464. doi: 10.1080/2162402X.2018.1434464. eCollection 2018. PubMed
Precise temporal regulation of alternative splicing during neural development. Weyn-Vanhentenryck SM, Feng H, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C. Nat Commun. 2018 Jun 6;9(1):2189. doi: 10.1038/s41467-018-04559-0. PubMed

Associated Plasmids
Spontaneous calcium transients in the immature adult-born neurons of the olfactory bulb. Maslyukov A, Li K, Su X, Kovalchuk Y, Garaschuk O. Cell Calcium. 2018 Sep;74:43-52. doi: 10.1016/j.ceca.2018.06.001. Epub 2018 Jun 6. PubMed
Imaging cell-type-specific dynamics of mRNAs in living mouse brain. Nwokafor C, Singer RH, Lim H. Methods. 2019 Mar 15;157:100-105. doi: 10.1016/j.ymeth.2018.07.009. Epub 2018 Jul 29. PubMed
Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease. Williams GP, Schonhoff AM, Jurkuvenaite A, Thome AD, Standaert DG, Harms AS. J Neuroinflammation. 2018 Aug 30;15(1):244. doi: 10.1186/s12974-018-1286-2. PubMed
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Sade-Feldman M, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG, Jenkins RW, Lieb DJ, Chen JH, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A, Hoover PJ, Villani AC, Ivanova E, Portell A, Lizotte PH, Aref AR, Eliane JP, Hammond MR, Vitzthum H, Blackmon SM, Li B, Gopalakrishnan V, Reddy SM, Cooper ZA, Paweletz CP, Barbie DA, Stemmer-Rachamimov A, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hacohen N. Cell. 2018 Nov 1;175(4):998-1013.e20. doi: 10.1016/j.cell.2018.10.038. PubMed
Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140. Ambrozkiewicz MC, Schwark M, Kishimoto-Suga M, Borisova E, Hori K, Salazar-Lazaro A, Rusanova A, Altas B, Piepkorn L, Bessa P, Schaub T, Zhang X, Rabe T, Ripamonti S, Rosario M, Akiyama H, Jahn O, Kobayashi T, Hoshino M, Tarabykin V, Kawabe H. Neuron. 2018 Dec 5;100(5):1097-1115.e15. doi: 10.1016/j.neuron.2018.10.008. Epub 2018 Nov 1. PubMed
Effective Glucose Uptake by Human Astrocytes Requires Its Sequestration in the Endoplasmic Reticulum by Glucose-6-Phosphatase-beta. Muller MS, Fouyssac M, Taylor CW. Curr Biol. 2018 Nov 5;28(21):3481-3486.e4. doi: 10.1016/j.cub.2018.08.060. Epub 2018 Oct 25. PubMed
Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Litvinchuk A, Wan YW, Swartzlander DB, Chen F, Cole A, Propson NE, Wang Q, Zhang B, Liu Z, Zheng H. Neuron. 2018 Dec 19;100(6):1337-1353.e5. doi: 10.1016/j.neuron.2018.10.031. Epub 2018 Nov 8. PubMed
Engineering Epigenetic Regulation Using Synthetic Read-Write Modules. Park M, Patel N, Keung AJ, Khalil AS. Cell. 2019 Jan 10;176(1-2):227-238.e20. doi: 10.1016/j.cell.2018.11.002. Epub 2018 Dec 6. PubMed

Associated Plasmids
Importin alpha5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1. Panayotis N, Sheinin A, Dagan SY, Tsoory MM, Rother F, Vadhvani M, Meshcheriakova A, Koley S, Marvaldi L, Song DA, Reuveny E, Eickholt BJ, Hartmann E, Bader M, Michaelevski I, Fainzilber M. Cell Rep. 2018 Dec 11;25(11):3169-3179.e7. doi: 10.1016/j.celrep.2018.11.066. PubMed
Light-Activated ROS Production Induces Synaptic Autophagy. Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, Garner CC, Ackermann F. J Neurosci. 2019 Mar 20;39(12):2163-2183. doi: 10.1523/JNEUROSCI.1317-18.2019. Epub 2019 Jan 17. PubMed
Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing. Tann JY, Wong LW, Sajikumar S, Ibanez CF. EMBO J. 2019 Mar 1;38(5). pii: embj.2018100989. doi: 10.15252/embj.2018100989. Epub 2019 Jan 28. PubMed
REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA. Cell Rep. 2019 Jan 29;26(5):1112-1127.e9. doi: 10.1016/j.celrep.2019.01.023. PubMed
Preclinical Evaluation of Long-Term Neuroprotective Effects of BDNF-Engineered Mesenchymal Stromal Cells as Intravitreal Therapy for Chronic Retinal Degeneration in Rd6 Mutant Mice. Lejkowska R, Kawa MP, Pius-Sadowska E, Roginska D, Luczkowska K, Machalinski B, Machalinska A. Int J Mol Sci. 2019 Feb 12;20(3). pii: ijms20030777. doi: 10.3390/ijms20030777. PubMed
Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs. Henderson NT, Le Marchand SJ, Hruska M, Hippenmeyer S, Luo L, Dalva MB. Elife. 2019 Feb 21;8. pii: 41563. doi: 10.7554/eLife.41563. PubMed
G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma. Wang Y, Yang J, Wild AT, Wu WH, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, Huse JT. Nat Commun. 2019 Feb 26;10(1):943. doi: 10.1038/s41467-019-08905-8. PubMed
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress. Jochner MCE, An J, Lattig-Tunnemann G, Kirchner M, Dagane A, Dittmar G, Dirnagl U, Eickholt BJ, Harms C. Sci Rep. 2019 Feb 28;9(1):3183. doi: 10.1038/s41598-019-39438-1. PubMed
ARNT2 Tunes Activity-Dependent Gene Expression through NCoR2-Mediated Repression and NPAS4-Mediated Activation. Sharma N, Pollina EA, Nagy MA, Yap EL, DiBiase FA, Hrvatin S, Hu L, Lin C, Greenberg ME. Neuron. 2019 Apr 17;102(2):390-406.e9. doi: 10.1016/j.neuron.2019.02.007. Epub 2019 Mar 4. PubMed
Histological Criteria that Distinguish Human and Mouse Bone Formed Within a Mouse Skeletal Repair Defect. Xin X, Jiang X, Wang L, Mikael P, McCarthy MB, Chen L, Mazzocca AD, Nukavarapu S, Lichtler AC, Rowe DW. J Histochem Cytochem. 2019 Jun;67(6):401-417. doi: 10.1369/0022155419836436. Epub 2019 Mar 8. PubMed
Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN. Zhang Q, Zhang Q, Jiang X, Ye Y, Liao H, Zhu F, Yan J, Luo L, Tian L, Jiang C, Chen Y, Liang X, Sun Y. Theranostics. 2019 Jan 30;9(4):986-1000. doi: 10.7150/thno.30199. eCollection 2019. PubMed
Estrogen-related receptor gamma regulates hepatic triglyceride metabolism through phospholipase A2 G12B. Chen L, Wu M, Zhang S, Tan W, Guan M, Feng L, Chen C, Tao J, Chen L, Qu L. FASEB J. 2019 Jul;33(7):7942-7952. doi: 10.1096/fj.201802704R. Epub 2019 Mar 28. PubMed
Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice. Cheng C, Yang K, Wu X, Zhang Y, Shan S, Gitler A, Ghosh A, Qiu Z. Transl Neurodegener. 2019 Apr 2;8:13. doi: 10.1186/s40035-019-0152-1. eCollection 2019. PubMed
The Orphan Nuclear Receptor TLX Represses Hes1 Expression, Thereby Affecting NOTCH Signaling and Lineage Progression in the Adult SEZ. Luque-Molina I, Shi Y, Abdullah Y, Monaco S, Holzl-Wenig G, Mandl C, Ciccolini F. Stem Cell Reports. 2019 Jul 9;13(1):132-146. doi: 10.1016/j.stemcr.2019.05.004. Epub 2019 Jun 6. PubMed
Ascorbate modulates the hypoxic pathway by increasing intracellular activity of the HIF hydroxylases in renal cell carcinoma cells. Wohlrab C, Kuiper C, Vissers MC, Phillips E, Robinson BA, Dachs GU. Hypoxia (Auckl). 2019 May 15;7:17-31. doi: 10.2147/HP.S201643. eCollection 2019. PubMed
Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. Huang YA, Zhou B, Nabet AM, Wernig M, Sudhof TC. J Neurosci. 2019 Sep 11;39(37):7408-7427. doi: 10.1523/JNEUROSCI.2994-18.2019. Epub 2019 Jul 22. PubMed
Single-Nucleotide-Resolution Computing and Memory in Living Cells. Farzadfard F, Gharaei N, Higashikuni Y, Jung G, Cao J, Lu TK. Mol Cell. 2019 Aug 22;75(4):769-780.e4. doi: 10.1016/j.molcel.2019.07.011. PubMed
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL. Mol Psychiatry. 2019 Aug 23. pii: 10.1038/s41380-019-0485-2. doi: 10.1038/s41380-019-0485-2. PubMed
Rabies Virus Pseudotyped with CVS-N2C Glycoprotein as a Powerful Tool for Retrograde Neuronal Network Tracing. Zhu X, Lin K, Liu Q, Yue X, Mi H, Huang X, He X, Wu R, Zheng D, Wei D, Jia L, Wang W, Manyande A, Wang J, Zhang Z, Xu F. Neurosci Bull. 2020 Mar;36(3):202-216. doi: 10.1007/s12264-019-00423-3. Epub 2019 Aug 23. PubMed
Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, Hartig W, Urlaub H, Chua JJ. Elife. 2019 Aug 27;8. pii: 47498. doi: 10.7554/eLife.47498. PubMed
Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Scheefhals N, Catsburg LAE, Westerveld ML, Blanpied TA, Hoogenraad CC, MacGillavry HD. Cell Rep. 2019 Oct 8;29(2):258-269.e8. doi: 10.1016/j.celrep.2019.08.102. PubMed
Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body. Martinez JC, Randolph LK, Iascone DM, Pernice HF, Polleux F, Hengst U. Neuron. 2019 Dec 4;104(5):931-946.e5. doi: 10.1016/j.neuron.2019.08.035. Epub 2019 Oct 9. PubMed
Mutational Analysis of Sigma-1 Receptor's Role in Synaptic Stability. Ryskamp DA, Zhemkov V, Bezprozvanny I. Front Neurosci. 2019 Sep 19;13:1012. doi: 10.3389/fnins.2019.01012. eCollection 2019. PubMed
Identification and characterization of Cardiac Glycosides as senolytic compounds. Triana-Martinez F, Picallos-Rabina P, Da Silva-Alvarez S, Pietrocola F, Llanos S, Rodilla V, Soprano E, Pedrosa P, Ferreiros A, Barradas M, Hernandez-Gonzalez F, Lalinde M, Prats N, Bernado C, Gonzalez P, Gomez M, Ikonomopoulou MP, Fernandez-Marcos PJ, Garcia-Caballero T, Del Pino P, Arribas J, Vidal A, Gonzalez-Barcia M, Serrano M, Loza MI, Dominguez E, Collado M. Nat Commun. 2019 Oct 21;10(1):4731. doi: 10.1038/s41467-019-12888-x. PubMed
Production of Lentivirus for the Establishment of CAR-T Cells. Lana MG, Strauss BE. Methods Mol Biol. 2020;2086:61-67. doi: 10.1007/978-1-0716-0146-4_4. PubMed
MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. Calvanese V, Nguyen AT, Bolan TJ, Vavilina A, Su T, Lee LK, Wang Y, Lay FD, Magnusson M, Crooks GM, Kurdistani SK, Mikkola HKA. Nature. 2019 Dec;576(7786):281-286. doi: 10.1038/s41586-019-1790-2. Epub 2019 Nov 27. PubMed
Novel anti-flavivirus drugs targeting the nucleolar distribution of core protein. Tokunaga M, Miyamoto Y, Suzuki T, Otani M, Inuki S, Esaki T, Nagao C, Mizuguchi K, Ohno H, Yoneda Y, Okamoto T, Oka M, Matsuura Y. Virology. 2020 Feb;541:41-51. doi: 10.1016/j.virol.2019.11.015. Epub 2019 Nov 29. PubMed
Choice of factors and medium impinge on success of ESC to TSC conversion. Kaiser F, Kubaczka C, Graf M, Langer N, Langkabel J, Arevalo L, Schorle H. Placenta. 2020 Jan 15;90:128-137. doi: 10.1016/j.placenta.2019.12.017. Epub 2019 Dec 23. PubMed
Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner. Latario CJ, Schoenfeld LW, Howarth CL, Pickrell LE, Begum F, Fischer DA, Grbovic-Huezo O, Leach SD, Sanchez Y, Smith KD, Higgs HN. Mol Biol Cell. 2020 Jun 1;31(12):1259-1272. doi: 10.1091/mbc.E19-11-0605. Epub 2020 Apr 8. PubMed
ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons. Willems J, de Jong APH, Scheefhals N, Mertens E, Catsburg LAE, Poorthuis RB, de Winter F, Verhaagen J, Meye FJ, MacGillavry HD. PLoS Biol. 2020 Apr 10;18(4):e3000665. doi: 10.1371/journal.pbio.3000665. PubMed

Associated Plasmids
Efficient Nonviral Stable Transgenesis Mediated by Retroviral Integrase. Chiang CY, Ligunas GD, Chin WC, Ni CW. Mol Ther Methods Clin Dev. 2020 May 3;17:1061-1070. doi: 10.1016/j.omtm.2020.04.020. eCollection 2020 Jun 12. PubMed
Establishment of stable Vero cell lines expressing TMPRSS2 and MSPL: A useful tool for propagating porcine epidemic diarrhea virus in the absence of exogenous trypsin. Wang X, Qiao X, Sui L, Zhao H, Li F, Tang YD, Shi W, Guo Y, Jiang Y, Wang L, Zhou H, Tang L, Xu Y, Li Y. Virulence. 2020 Dec;11(1):669-685. doi: 10.1080/21505594.2020.1770491. PubMed
TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2). Woolums BM, McCray BA, Sung H, Tabuchi M, Sullivan JM, Ruppell KT, Yang Y, Mamah C, Aisenberg WH, Saavedra-Rivera PC, Larin BS, Lau AR, Robinson DN, Xiang Y, Wu MN, Sumner CJ, Lloyd TE. Nat Commun. 2020 May 29;11(1):2679. doi: 10.1038/s41467-020-16411-5. PubMed
Effects of Inorganic Arsenic on Human Prostate Stem-Progenitor Cell Transformation, Autophagic Flux Blockade, and NRF2 Pathway Activation. Xie L, Hu WY, Hu DP, Shi G, Li Y, Yang J, Prins GS. Environ Health Perspect. 2020 Jun;128(6):67008. doi: 10.1289/EHP6471. Epub 2020 Jun 11. PubMed
Prickle2 and Igsf9b coordinately regulate the cytoarchitecture of the axon initial segment. Chowdhury MIH, Nishioka T, Mishima N, Ohtsuka T, Kaibuchi K, Tsuboi D. Cell Struct Funct. 2020 Jul 8. doi: 10.1247/csf.20028. PubMed
Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition. Fassl A, Brain C, Abu-Remaileh M, Stukan I, Butter D, Stepien P, Feit AS, Bergholz J, Michowski W, Otto T, Sheng Q, Loo A, Michael W, Tiedt R, DeAngelis C, Schiff R, Jiang B, Jovanovic B, Nowak K, Ericsson M, Cameron M, Gray N, Dillon D, Zhao JJ, Sabatini DM, Jeselsohn R, Brown M, Polyak K, Sicinski P. Sci Adv. 2020 Jun 17;6(25):eabb2210. doi: 10.1126/sciadv.abb2210. eCollection 2020 Jun. PubMed
Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and beta-catenin induction in mesothelium. Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S. Redox Biol. 2020 Sep;36:101616. doi: 10.1016/j.redox.2020.101616. Epub 2020 Jun 24. PubMed
Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation. Yamulla RJ, Nalubola S, Flesken-Nikitin A, Nikitin AY, Schimenti JC. Cell Rep. 2020 Sep 1;32(9):108086. doi: 10.1016/j.celrep.2020.108086. PubMed
Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. Lindhout FW, Kooistra R, Portegies S, Herstel LJ, Stucchi R, Snoek BL, Altelaar AM, MacGillavry HD, Wierenga CJ, Hoogenraad CC. Elife. 2020 Sep 17;9. pii: 58124. doi: 10.7554/eLife.58124. PubMed
CCR5 tyrosine sulfation heterogeneity generates cell surface receptor subpopulations with different ligand binding properties. Scurci I, Akondi KB, Pinheiro I, Paolini-Bertrand M, Borgeat A, Cerini F, Hartley O. Biochim Biophys Acta Gen Subj. 2021 Jan;1865(1):129753. doi: 10.1016/j.bbagen.2020.129753. Epub 2020 Sep 28. PubMed
In Vivo Gene Delivery of STC2 Promotes Axon Regeneration in Sciatic Nerves. Jeon Y, Shin JE, Kwon M, Cho E, Cavalli V, Cho Y. Mol Neurobiol. 2021 Feb;58(2):750-760. doi: 10.1007/s12035-020-02155-2. Epub 2020 Oct 4. PubMed
Sirt7-p21 Signaling Pathway Mediates Glucocorticoid-Induced Inhibition of Mouse Neural Stem Cell Proliferation. Alnoud MAH, Chen W, Liu N, Zhu W, Qiao J, Chang S, Wu Y, Wang S, Yang Y, Sun Q, Kang J. Neurotox Res. 2021 Apr;39(2):444-455. doi: 10.1007/s12640-020-00294-x. Epub 2020 Oct 6. PubMed
Generation of neural progenitor cells from porcine-induced pluripotent stem cells. Machado LS, Pieri NCG, Botigelli RC, de Castro RVG, de Souza AF, Bridi A, Lima MA, Fantinato Neto P, Pessoa LVF, Martins SMMK, De Andrade AFC, Freude KK, Bressan FF. J Tissue Eng Regen Med. 2020 Dec;14(12):1880-1891. doi: 10.1002/term.3143. Epub 2020 Nov 23. PubMed
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. Semesta KM, Tian R, Kampmann M, von Zastrow M, Tsvetanova NG. PLoS Genet. 2020 Oct 14;16(10):e1009103. doi: 10.1371/journal.pgen.1009103. eCollection 2020 Oct. PubMed
Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation. Liu S, Harmston N, Glaser TL, Wong Y, Zhong Z, Madan B, Virshup DM, Petretto E. Genome Med. 2020 Oct 22;12(1):89. doi: 10.1186/s13073-020-00788-5. PubMed
An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells. Jones RD, Qian Y, Siciliano V, DiAndreth B, Huh J, Weiss R, Del Vecchio D. Nat Commun. 2020 Nov 10;11(1):5690. doi: 10.1038/s41467-020-19126-9. PubMed
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival. Fukuda Y, Pazyra-Murphy MF, Silagi ES, Tasdemir-Yilmaz OE, Li Y, Rose L, Yeoh ZC, Vangos NE, Geffken EA, Seo HS, Adelmant G, Bird GH, Walensky LD, Marto JA, Dhe-Paganon S, Segal RA. J Cell Biol. 2021 Jan 4;220(1). pii: 211577. doi: 10.1083/jcb.202005051. PubMed

Associated Plasmids
A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors. Costa B, Fletcher MNC, Boskovic P, Ivanova EL, Eisemann T, Lohr S, Bunse L, Lower M, Burchard S, Korshunov A, Coltella N, Cusimano M, Naldini L, Liu HK, Platten M, Radlwimmer B, Angel P, Peterziel H. Cancers (Basel). 2021 Jan 10;13(2). pii: cancers13020230. doi: 10.3390/cancers13020230. PubMed
Sirtuin 6 is a regulator of dendrite morphogenesis in rat hippocampal neurons. Matsuno H, Tsuchimine S, Fukuzato N, O'Hashi K, Kunugi H, Sohya K. Neurochem Int. 2021 May;145:104959. doi: 10.1016/j.neuint.2021.104959. Epub 2021 Jan 12. PubMed
Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles. Vilcaes AA, Chanaday NL, Kavalali ET. Neuron. 2021 Mar 17;109(6):971-983.e5. doi: 10.1016/j.neuron.2021.01.007. Epub 2021 Jan 28. PubMed
Protocol to Study the Role of Extracellular Vesicles During Induced Stem Cell Differentiation. Roballo KCS, Ambrosio CE, da Silveira JC. Methods Mol Biol. 2021;2273:63-73. doi: 10.1007/978-1-0716-1246-0_3. PubMed
Presence of antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 in COVID-19 plasma. Tso FY, Lidenge SJ, Poppe LK, Pena PB, Privatt SR, Bennett SJ, Ngowi JR, Mwaiselage J, Belshan M, Siedlik JA, Raine MA, Ochoa JB, Garcia-Diaz J, Nossaman B, Buckner L, Roberts WM, Dean MJ, Ochoa AC, West JT, Wood C. PLoS One. 2021 Mar 4;16(3):e0247640. doi: 10.1371/journal.pone.0247640. eCollection 2021. PubMed
Generation and Breeding of EGFP-Transgenic Marmoset Monkeys: Cell Chimerism and Implications for Disease Modeling. Drummer C, Vogt EJ, Heistermann M, Roshani B, Becker T, Matz-Rensing K, Kues WA, Kugler S, Behr R. Cells. 2021 Feb 27;10(3). pii: cells10030505. doi: 10.3390/cells10030505. PubMed
Presynaptic store-operated Ca(2+) entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress. Chanaday NL, Nosyreva E, Shin OH, Zhang H, Aklan I, Atasoy D, Bezprozvanny I, Kavalali ET. Neuron. 2021 Apr 21;109(8):1314-1332.e5. doi: 10.1016/j.neuron.2021.02.023. Epub 2021 Mar 11. PubMed
Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Chen MJ, Ramesha S, Weinstock LD, Gao T, Ping L, Xiao H, Dammer EB, Duong DD, Levey AI, Lah JJ, Seyfried NT, Wood LB, Rangaraju S. J Neurosci Res. 2021 Jun;99(6):1704-1721. doi: 10.1002/jnr.24829. Epub 2021 Mar 17. PubMed
Podoplanin is required for tumor cell invasion in cutaneous squamous cell carcinoma. Schwab M, Lohr S, Schneider J, Kaiser M, Krunic D, Helbig D, Geraud C, Angel P. Exp Dermatol. 2021 Mar 30. doi: 10.1111/exd.14344. PubMed
Centrosome-mediated microtubule remodeling during axon formation in human iPSC-derived neurons. Lindhout FW, Portegies S, Kooistra R, Herstel LJ, Stucchi R, Hummel JJA, Scheefhals N, Katrukha EA, Altelaar M, MacGillavry HD, Wierenga CJ, Hoogenraad CC. EMBO J. 2021 May 17;40(10):e106798. doi: 10.15252/embj.2020106798. Epub 2021 Apr 9. PubMed
High-pulse-energy multiphoton imaging of neurons and oligodendrocytes in deep murine brain with a fiber laser. Redlich MJ, Prall B, Canto-Said E, Busarov Y, Shirinyan-Tuka L, Meah A, Lim H. Sci Rep. 2021 Apr 12;11(1):7950. doi: 10.1038/s41598-021-86924-6. PubMed
An Intronic Variant of CHD7 Identified in Autism Patients Interferes with Neuronal Differentiation and Development. Zhang R, He H, Yuan B, Wu Z, Wang X, Du Y, Chen Y, Qiu Z. Neurosci Bull. 2021 Aug;37(8):1091-1106. doi: 10.1007/s12264-021-00685-w. Epub 2021 May 4. PubMed
Novel high-affinity EGFRvIII-specific chimeric antigen receptor T cells effectively eliminate human glioblastoma. Abbott RC, Verdon DJ, Gracey FM, Hughes-Parry HE, Iliopoulos M, Watson KA, Mulazzani M, Luong K, D'Arcy C, Sullivan LC, Kiefel BR, Cross RS, Jenkins MR. Clin Transl Immunology. 2021 May 9;10(5):e1283. doi: 10.1002/cti2.1283. eCollection 2021. PubMed
HIV-based lentiviral vectors: origin and sequence differences. Johnson NM, Alvarado AF, Moffatt TN, Edavettal JM, Swaminathan TA, Braun SE. Mol Ther Methods Clin Dev. 2021 Mar 27;21:451-465. doi: 10.1016/j.omtm.2021.03.018. eCollection 2021 Jun 11. PubMed
PINK1 Activation Attenuates Impaired Neuronal-Like Differentiation and Synaptogenesis and Mitochondrial Dysfunction in Alzheimer's Disease Trans-Mitochondrial Cybrid Cells. Du F, Yu Q, Yan SS. J Alzheimers Dis. 2021;81(4):1749-1761. doi: 10.3233/JAD-210095. PubMed
Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism. Yang QQ, Zhai YQ, Wang HF, Cai YC, Ma XY, Yin YQ, Li YD, Zhou GM, Zhang X, Hu G, Zhou JW. Cell Rep. 2021 May 18;35(7):109127. doi: 10.1016/j.celrep.2021.109127. PubMed
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology. El Manaa W, Duplan E, Goiran T, Lauritzen I, Vaillant Beuchot L, Lacas-Gervais S, Morais VA, You H, Qi L, Salazar M, Ozcan U, Chami M, Checler F, Alves da Costa C. Autophagy. 2021 Dec;17(12):4363-4385. doi: 10.1080/15548627.2021.1917129. Epub 2021 May 24. PubMed
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Elife. 2021 May 26;10. pii: 67624. doi: 10.7554/eLife.67624. PubMed
Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH. Chin MY, Patwardhan AR, Ang KH, Wang AL, Alquezar C, Welch M, Nguyen PT, Grabe M, Molofsky AV, Arkin MR, Kao AW. ACS Sens. 2021 Jun 8. doi: 10.1021/acssensors.0c02318. PubMed

Associated Plasmids
Utilizing In Vivo Postnatal Electroporation to Study Cerebellar Granule Neuron Morphology and Synapse Development. Chan U, Gautam D, West AE. J Vis Exp. 2021 Jun 9;(172). doi: 10.3791/62568. PubMed
Dual Color, Live Imaging of Vesicular Transport in Axons of Cultured Sensory Neurons. Bekku Y, Salzer JL. Bio Protoc. 2021 Jun 20;11(12):e4067. doi: 10.21769/BioProtoc.4067. eCollection 2021 Jun 20. PubMed
YB-1 Is Altered in Pregnancy-Associated Disorders and Affects Trophoblast in Vitro Properties via Alternation of Multiple Molecular Traits. Stojanovska V, Shah A, Woidacki K, Fischer F, Bauer M, Lindquist JA, Mertens PR, Zenclussen AC. Int J Mol Sci. 2021 Jul 5;22(13). pii: ijms22137226. doi: 10.3390/ijms22137226. PubMed
A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength. Horvath PM, Chanaday NL, Alten B, Kavalali ET, Monteggia LM. Cell Rep. 2021 Aug 3;36(5):109467. doi: 10.1016/j.celrep.2021.109467. PubMed
Lentiviral transduction of neonatal rat ventricular myocytes preserves ultrastructural features of genetically modified cells. Consonni SR, de Carvalho ACPV, Mauro AB, Franchini KG, Bajgelman MC. Virology. 2021 Oct;562:190-196. doi: 10.1016/j.virol.2021.07.015. Epub 2021 Jul 31. PubMed
Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection. He J, Nissim L, Soleimany AP, Binder-Nissim A, Fleming HE, Lu TK, Bhatia SN. ACS Synth Biol. 2021 Sep 17;10(9):2231-2242. doi: 10.1021/acssynbio.1c00133. Epub 2021 Aug 31. PubMed
Nectin-1 Is an Entry Mediator for Varicella-Zoster Virus Infection of Human Neurons. Rajbhandari L, Shukla P, Jagdish B, Mandalla A, Li Q, Ali MA, Lee H, Lee G, Sadaoka T, Cohen JI, Venkatesan A. J Virol. 2021 Oct 27;95(22):e0122721. doi: 10.1128/JVI.01227-21. Epub 2021 Sep 1. PubMed
Cytoplasmic Tail Truncation of SARS-CoV-2 Spike Protein Enhances Titer of Pseudotyped Vectors but Masks the Effect of the D614G Mutation. Chen HY, Huang C, Tian L, Huang X, Zhang C, Llewellyn GN, Rogers GL, Andresen K, O'Gorman MRG, Chen YW, Cannon PM. J Virol. 2021 Oct 27;95(22):e0096621. doi: 10.1128/JVI.00966-21. Epub 2021 Sep 8. PubMed
Synaptotagmin 7 is targeted to the axonal plasma membrane through gamma-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons. Vevea JD, Kusick GF, Courtney KC, Chen E, Watanabe S, Chapman ER. Elife. 2021 Sep 20;10. pii: 67261. doi: 10.7554/eLife.67261. PubMed

Associated Plasmids
Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment. Borgmeyer M, Coman C, Has C, Schott HF, Li T, Westhoff P, Cheung YFH, Hoffmann N, Yuanxiang P, Behnisch T, Gomes GM, Dumenieu M, Schweizer M, Chocholouskova M, Holcapek M, Mikhaylova M, Kreutz MR, Ahrends R. Cell Rep. 2021 Oct 5;37(1):109797. doi: 10.1016/j.celrep.2021.109797. PubMed
Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin. Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S. Redox Biol. 2021 Nov;47:102174. doi: 10.1016/j.redox.2021.102174. Epub 2021 Oct 21. PubMed
Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring. Chen W, Liu N, Shen S, Zhu W, Qiao J, Chang S, Dong J, Bai M, Ma L, Wang S, Jia W, Guo X, Li A, Xi J, Jiang C, Kang J. Cell Rep. 2021 Nov 2;37(5):109912. doi: 10.1016/j.celrep.2021.109912. PubMed
RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development. Wang J, Miao Y, Wicklein R, Sun Z, Wang J, Jude KM, Fernandes RA, Merrill SA, Wernig M, Garcia KC, Sudhof TC. Cell. 2021 Nov 24;184(24):5869-5885.e25. doi: 10.1016/j.cell.2021.10.016. Epub 2021 Nov 9. PubMed
Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons. Gao H, Zheng W, Li C, Xu H. Int J Mol Sci. 2021 Oct 27;22(21). pii: ijms222111582. doi: 10.3390/ijms222111582. PubMed
Mutations of the histone linker H1-4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4. Tremblay MW, Green MV, Goldstein BM, Aldridge AI, Rosenfeld JA, Streff H, Tan WD, Craigen W, Bekheirnia N, Al Tala S, West AE, Jiang YH. Hum Mol Genet. 2021 Nov 12. pii: 6414843. doi: 10.1093/hmg/ddab321. PubMed
Rational design and construction of multi-copy biomanufacturing islands in mammalian cells. Altamura R, Doshi J, Benenson Y. Nucleic Acids Res. 2022 Jan 11;50(1):561-578. doi: 10.1093/nar/gkab1214. PubMed
All-optical monitoring of excitation-secretion coupling demonstrates that SV2A functions downstream of evoked Ca(2+) entry. Bradberry MM, Chapman ER. J Physiol. 2022 Feb;600(3):645-654. doi: 10.1113/JP282601. Epub 2022 Jan 13. PubMed

Associated Plasmids
Gene expression predicts dormant metastatic breast cancer cell phenotype. Ren Q, Khoo WH, Corr AP, Phan TG, Croucher PI, Stewart SA. Breast Cancer Res. 2022 Jan 29;24(1):10. doi: 10.1186/s13058-022-01503-5. PubMed
Pharmacological perturbation of CXCL1 signaling alleviates neuropathogenesis in a model of HEVA71 infection. Gunaseelan S, Ariffin MZ, Khanna S, Ooi MH, Perera D, Chu JJH, Chua JJE. Nat Commun. 2022 Feb 16;13(1):890. doi: 10.1038/s41467-022-28533-z. PubMed
Characterization of the canine CD20 as a therapeutic target for comparative passive immunotherapy. Dias JNR, Almeida A, Andre AS, Aguiar SI, Bule P, Nogueira S, Oliveira SS, Carrapico B, Gil S, Tavares L, Aires-da-Silva F. Sci Rep. 2022 Feb 17;12(1):2678. doi: 10.1038/s41598-022-06549-1. PubMed
Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress. Fernandez A, Bautista M, Wu L, Pinaud F. J Cell Sci. 2022 Mar 15;135(6). pii: 274432. doi: 10.1242/jcs.258969. Epub 2022 Mar 30. PubMed
Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-kappaB signal pathways. Cheng P, Zhang R, Shan S, Yuan B, Chen J, Qiu Z, Du Y. Neurosci Lett. 2022 Apr 1;775:136533. doi: 10.1016/j.neulet.2022.136533. Epub 2022 Feb 15. PubMed
Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues. Skylar-Scott MA, Huang JY, Lu A, Ng AHM, Duenki T, Liu S, Nam LL, Damaraju S, Church GM, Lewis JA. Nat Biomed Eng. 2022 Apr;6(4):449-462. doi: 10.1038/s41551-022-00856-8. Epub 2022 Mar 24. PubMed
ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1. Zhong X, Wang T, Zhang W, Wang M, Xie Y, Dai L, He X, Madhusudhan T, Zeng H, Wang H. J Biol Chem. 2022 Jun;298(6):101989. doi: 10.1016/j.jbc.2022.101989. Epub 2022 Apr 28. PubMed
Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke. Hoffmann CJ, Kuffner MTC, Lips J, Lorenz S, Endres M, Harms C. Front Physiol. 2022 Apr 26;13:887180. doi: 10.3389/fphys.2022.887180. eCollection 2022. PubMed
Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine. Guan M, Lim L, Holguin L, Han T, Vyas V, Urak R, Miller A, Browning DL, Echavarria L, Li S, Li S, Chang WC, Scott T, Yazaki P, Morris KV, Cardoso AA, Blanchard MS, Le Verche V, Forman SJ, Zaia JA, Burnett JC, Wang X. Mol Ther Methods Clin Dev. 2022 Apr 13;25:344-359. doi: 10.1016/j.omtm.2022.04.007. eCollection 2022 Jun 9. PubMed
Proteomic and functional analyses of the periodic membrane skeleton in neurons. Zhou R, Han B, Nowak R, Lu Y, Heller E, Xia C, Chishti AH, Fowler VM, Zhuang X. Nat Commun. 2022 Jun 9;13(1):3196. doi: 10.1038/s41467-022-30720-x. PubMed
Polybasic Patches in Both C2 Domains of Synaptotagmin-1 Are Required for Evoked Neurotransmitter Release. Wu Z, Ma L, Courtney NA, Zhu J, Landajuela A, Zhang Y, Chapman ER, Karatekin E. J Neurosci. 2022 Jul 27;42(30):5816-5829. doi: 10.1523/JNEUROSCI.1385-21.2022. Epub 2022 Jun 14. PubMed
Ca(2+) signaling in postsynaptic neurons: Neuroplastin-65 regulates the interplay between plasma membrane Ca(2+) ATPases and ionotropic glutamate receptors. Malci A, Lin X, Sandoval R, Gundelfinger ED, Naumann M, Seidenbecher CI, Herrera-Molina R. Cell Calcium. 2022 Sep;106:102623. doi: 10.1016/j.ceca.2022.102623. Epub 2022 Jul 6. PubMed
Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells. Sanchez-Burgos L, Navarro-Gonzalez B, Garcia-Martin S, Sirozh O, Mota-Pino J, Fueyo-Marcos E, Tejero H, Anton ME, Murga M, Al-Shahrour F, Fernandez-Capetillo O. EMBO Mol Med. 2022 Sep 7;14(9):e15855. doi: 10.15252/emmm.202215855. Epub 2022 Jul 21. PubMed
Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment. Lopes R, Caetano J, Barahona F, Pestana C, Ferreira BV, Lourenco D, Queiros AC, Bilreiro C, Shemesh N, Beck HC, Carvalho AS, Matthiesen R, Bogen B, Costa-Silva B, Serre K, Carneiro EA, Joao C. Front Immunol. 2022 Jul 7;13:909880. doi: 10.3389/fimmu.2022.909880. eCollection 2022. PubMed
Developmental dynamics of RNA translation in the human brain. Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME. Nat Neurosci. 2022 Oct;25(10):1353-1365. doi: 10.1038/s41593-022-01164-9. Epub 2022 Sep 28. PubMed
Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP. Mol Psychiatry. 2023 Feb;28(2):746-758. doi: 10.1038/s41380-022-01818-x. Epub 2022 Oct 7. PubMed
Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors. Ma L, Mei Y, Xu P, Cheng Y, You Z, Ji X, Zhuang D, Zhou W, Chen Y, Xiong M. iScience. 2022 Sep 20;25(10):105172. doi: 10.1016/j.isci.2022.105172. eCollection 2022 Oct 21. PubMed
miR-196a enhances polymerization of neuronal microfilaments through suppressing IMP3 and upregulating IGF2 in Huntington's disease. Yang HI, Huang PY, Chan SC, Tung CW, Cheng PH, Chen CM, Yang SH. Mol Ther Nucleic Acids. 2022 Oct 10;30:286-299. doi: 10.1016/j.omtn.2022.10.002. eCollection 2022 Dec 13. PubMed
Niraparib-induced STAT3 inhibition increases its antitumor effects. Zhao Q, Kohut A, Li YJ, Martincuks A, Austria T, Zhang C, Santiago NL, Borrero RM, Phan XT, Melstrom L, Rodriguez-Rodriguez L, Yu H. Front Oncol. 2022 Oct 17;12:966492. doi: 10.3389/fonc.2022.966492. eCollection 2022. PubMed
Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons. Watson ET, Pauers MM, Seibert MJ, Vevea JD, Chapman ER. Elife. 2023 Feb 2;12:e82568. doi: 10.7554/eLife.82568. PubMed

Associated Plasmids
Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion. Seibert MJ, Evans CS, Stanley KS, Wu Z, Chapman ER. J Neurosci. 2023 Mar 1;43(9):1475-1491. doi: 10.1523/JNEUROSCI.1857-22.2023. Epub 2023 Feb 2. PubMed

Associated Plasmids
A rabies virus-based toolkit for efficient retrograde labeling and monosynaptic tracing. Lin KZ, Li L, Ma WY, Yang X, Han ZP, Luo NS, Wang J, Xu FQ. Neural Regen Res. 2023 Aug;18(8):1827-1833. doi: 10.4103/1673-5374.358618. PubMed
Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening. An H, Tian X, Huang Y, Zhang JR. STAR Protoc. 2023 Mar 17;4(1):102065. doi: 10.1016/j.xpro.2023.102065. Epub 2023 Jan 24. PubMed
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology. Gouveia Roque C, Chung KM, McCurdy EP, Jagannathan R, Randolph LK, Herline-Killian K, Baleriola J, Hengst U. Sci Adv. 2023 Mar 3;9(9):eadd2671. doi: 10.1126/sciadv.add2671. Epub 2023 Mar 3. PubMed
Mitofusin 2 Sustains the Axonal Mitochondrial Network to Support Presynaptic Ca(2+) Homeostasis and the Synaptic Vesicle Cycle in Rat Hippocampal Axons. Vevea JD, Chapman ER. J Neurosci. 2023 May 10;43(19):3421-3438. doi: 10.1523/JNEUROSCI.1356-22.2023. Epub 2023 Mar 30. PubMed

Associated Plasmids
A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes. Pao PC, Seo J, Lee A, Kritskiy O, Patnaik D, Penney J, Raju RM, Geigenmuller U, Silva MC, Lucente DE, Gusella JF, Dickerson BC, Loon A, Yu MX, Bula M, Yu M, Haggarty SJ, Tsai LH. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2217864120. doi: 10.1073/pnas.2217864120. Epub 2023 Apr 12. PubMed
Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes. Lee HJ, Lee J, Yang MJ, Kim YC, Hong SP, Kim JM, Hwang GS, Koh GY. Nat Commun. 2023 May 13;14(1):2754. doi: 10.1038/s41467-023-38433-5. PubMed
The lipase cofactor CGI58 controls placental lipolysis. Guerrero-Santoro J, Morizane M, Oh SY, Mishima T, Goff JP, Bildirici I, Sadovsky E, Ouyang Y, Tyurin VA, Tyurina YY, Kagan VE, Sadovsky Y. JCI Insight. 2023 May 22;8(10):e168717. doi: 10.1172/jci.insight.168717. PubMed
Allele-specific gene-editing approach for vision loss restoration in RHO-associated retinitis pigmentosa. Liu X, Qiao J, Jia R, Zhang F, Meng X, Li Y, Yang L. Elife. 2023 Jun 5;12:e84065. doi: 10.7554/eLife.84065. PubMed
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination. Chou CW, Hung CN, Chiu CH, Tan X, Chen M, Chen CC, Saeed M, Hsu CW, Liss MA, Wang CM, Lai Z, Alvarez N, Osmulski PA, Gaczynska ME, Lin LL, Ortega V, Kirma NB, Xu K, Liu Z, Kumar AP, Taverna JA, Velagaleti GVN, Chen CL, Zhang Z, Huang TH. Nat Commun. 2023 Oct 17;14(1):6569. doi: 10.1038/s41467-023-42303-5. PubMed
Abl2 repairs microtubules and phase separates with tubulin to promote microtubule nucleation. Duan D, Lyu W, Chai P, Ma S, Wu K, Wu C, Xiong Y, Sestan N, Zhang K, Koleske AJ. Curr Biol. 2023 Nov 6;33(21):4582-4598.e10. doi: 10.1016/j.cub.2023.09.018. Epub 2023 Oct 18. PubMed
RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling. Sempert K, Shohayeb B, Lanoue V, O'Brien EA, Flores C, Cooper HM. Front Mol Neurosci. 2023 Oct 19;16:1253801. doi: 10.3389/fnmol.2023.1253801. eCollection 2023. PubMed
The juxtamembrane linker of synaptotagmin 1 regulates Ca(2+) binding via liquid-liquid phase separation. Mehta N, Mondal S, Watson ET, Cui Q, Chapman ER. Nat Commun. 2024 Jan 4;15(1):262. doi: 10.1038/s41467-023-44414-5. PubMed

Associated Plasmids
Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients. Lidenge SJ, Yalcin D, Bennett SJ, Ngalamika O, Kweyamba BB, Mwita CJ, Tso FY, Mwaiselage J, West JT, Wood C. Viruses. 2024 Mar 13;16(3):448. doi: 10.3390/v16030448. PubMed
Light-gated Integrator for Highlighting Kinase Activity in Living Cells. Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585554. doi: 10.1101/2024.03.18.585554. PubMed
The response of Dual-leucine zipper kinase (DLK) to nocodazole: Evidence for a homeostatic cytoskeletal repair mechanism. DeVault L, Mateusiak C, Palucki J, Brent M, Milbrandt J, DiAntonio A. PLoS One. 2024 Apr 4;19(4):e0300539. doi: 10.1371/journal.pone.0300539. eCollection 2024. PubMed
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Cell. 2024 May 9;187(10):2446-2464.e22. doi: 10.1016/j.cell.2024.03.015. Epub 2024 Apr 5. PubMed
Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program. Gao L, Lee H, Goodman JH, Ding L. Cell. 2024 May 23;187(11):2801-2816.e17. doi: 10.1016/j.cell.2024.03.032. Epub 2024 Apr 23. PubMed
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut. Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Immunity. 2024 May 14;57(5):1019-1036.e9. doi: 10.1016/j.immuni.2024.04.001. Epub 2024 Apr 26. PubMed
Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids. Dao L, You Z, Lu L, Xu T, Sarkar AK, Zhu H, Liu M, Calandrelli R, Yoshida G, Lin P, Miao Y, Mierke S, Kalva S, Zhu H, Gu M, Vadivelu S, Zhong S, Huang LF, Guo Z. Cell Stem Cell. 2024 Jun 6;31(6):818-833.e11. doi: 10.1016/j.stem.2024.04.019. Epub 2024 May 15. PubMed
Aplp1 interacts with Lag3 to facilitate transmission of pathologic alpha-synuclein. Mao X, Gu H, Kim D, Kimura Y, Wang N, Xu E, Kumbhar R, Ming X, Wang H, Chen C, Zhang S, Jia C, Liu Y, Bian H, Karuppagounder SS, Akkentli F, Chen Q, Jia L, Hwang H, Lee SH, Ke X, Chang M, Li A, Yang J, Rastegar C, Sriparna M, Ge P, Brahmachari S, Kim S, Zhang S, Shimoda Y, Saar M, Liu H, Kweon SH, Ying M, Workman CJ, Vignali DAA, Muller UC, Liu C, Ko HS, Dawson VL, Dawson TM. Nat Commun. 2024 May 31;15(1):4663. doi: 10.1038/s41467-024-49016-3. PubMed
MYCT1 controls environmental sensing in human haematopoietic stem cells. Aguade-Gorgorio J, Jami-Alahmadi Y, Calvanese V, Kardouh M, Fares I, Johnson H, Rezek V, Ma F, Magnusson M, Wang Y, Shin JE, Nance KJ, Goodridge HS, Liebscher S, Schenke-Layland K, Crooks GM, Wohlschlegel JA, Mikkola HKA. Nature. 2024 Jun;630(8016):412-420. doi: 10.1038/s41586-024-07478-x. Epub 2024 Jun 5. PubMed
A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction. Bansal P, Banda EC, Glatt-Deeley HR, Stoddard CE, Linsley JW, Arora N, Deleschaux C, Ahern DT, Kondaveeti Y, Massey RE, Nicouleau M, Wang S, Sabariego-Navarro M, Dierssen M, Finkbeiner S, Pinter SF. Sci Adv. 2024 Jun 7;10(23):eadj0385. doi: 10.1126/sciadv.adj0385. Epub 2024 Jun 7. PubMed

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