pCAG-CreERT2 Citations (47)
Originally described in: Controlled expression of transgenes introduced by in vivo electroporation.Matsuda T, Cepko CL Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1027-32. doi: 10.1073/pnas.0610155104 PubMed Journal
Articles Citing pCAG-CreERT2
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| Transgene excision in zebrafish using the phiC31 integrase. Lister JA. Genesis. 2010 Jan 21. 48(2):137-143. PubMed |
| Inducible transgenic mouse models. Saunders TL. Methods Mol Biol. 2011;693:103-15. doi: 10.1007/978-1-60761-974-1_7. PubMed |
| Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus. Pak T, Yoo S, Miranda-Angulo AL, Wang H, Blackshaw S. PLoS One. 2014 Apr 3;9(4):e90381. doi: 10.1371/journal.pone.0090381. eCollection 2014. PubMed |
| Upk3b is dispensable for development and integrity of urothelium and mesothelium. Rudat C, Grieskamp T, Rohr C, Airik R, Wrede C, Hegermann J, Herrmann BG, Schuster-Gossler K, Kispert A. PLoS One. 2014 Nov 12;9(11):e112112. doi: 10.1371/journal.pone.0112112. eCollection 2014. PubMed |
Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish.
Horstick EJ, Jordan DC, Bergeron SA, Tabor KM, Serpe M, Feldman B, Burgess HA.
Nucleic Acids Res. 2015 Jan 27. pii: gkv035.
PubMed
Associated Plasmids |
| Leukemia stem cells in T-ALL require active Hif1alpha and Wnt signaling. Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. PubMed |
| Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Nature. 2015 Jul 9;523(7559):226-30. doi: 10.1038/nature14582. Epub 2015 Jun 22. PubMed |
| A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity. Yuan L, Chan GC, Beeler D, Janes L, Spokes KC, Dharaneeswaran H, Mojiri A, Adams WJ, Sciuto T, Garcia-Cardena G, Molema G, Kang PM, Jahroudi N, Marsden PA, Dvorak A, Regan ER, Aird WC. Nat Commun. 2016 Jan 8;7:10160. doi: 10.1038/ncomms10160. PubMed |
| Inhibition of KDM6 activity during murine ESC differentiation induces DNA damage. Hofstetter C, Kampka JM, Huppertz S, Weber H, Schlosser A, Muller AM, Becker M. J Cell Sci. 2016 Feb 15;129(4):788-803. doi: 10.1242/jcs.175174. Epub 2016 Jan 12. PubMed |
| Cutting Edge: Engineering Active IKKbeta in T Cells Drives Tumor Rejection. Evaristo C, Spranger S, Barnes SE, Miller ML, Molinero LL, Locke FL, Gajewski TF, Alegre ML. J Immunol. 2016 Apr 1;196(7):2933-8. doi: 10.4049/jimmunol.1501144. Epub 2016 Feb 22. PubMed |
| Generation and characterization of tamoxifen-inducible Pax9-CreER knock-in mice using CrispR/Cas9. Feng J, Jing J, Sanchez-Lara PA, Bootwalla MS, Buckley J, Wu N, Yan Y, Chai Y. Genesis. 2016 Sep;54(9):490-6. doi: 10.1002/dvg.22956. Epub 2016 Jul 26. PubMed |
| A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon. Gao D, Zhan Y, Di W, Moore AR, Sher JJ, Guan Y, Wang S, Zhang Z, Murphy DA, Sawyers CL, Chi P, Chen Y. PLoS One. 2016 Aug 18;11(8):e0161084. doi: 10.1371/journal.pone.0161084. eCollection 2016. PubMed |
| UbC-StarTrack, a clonal method to target the entire progeny of individual progenitors. Figueres-Onate M, Garcia-Marques J, Lopez-Mascaraque L. Sci Rep. 2016 Sep 22;6:33896. doi: 10.1038/srep33896. PubMed |
| Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis. Xu J, Yao G, Ru Y, Xie S. Mol Reprod Dev. 2016 Dec 28. doi: 10.1002/mrd.22772. PubMed |
| Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Decker RS, Um HB, Dyment NA, Cottingham N, Usami Y, Enomoto-Iwamoto M, Kronenberg MS, Maye P, Rowe DW, Koyama E, Pacifici M. Dev Biol. 2017 Jun 1;426(1):56-68. doi: 10.1016/j.ydbio.2017.04.006. Epub 2017 Apr 21. PubMed |
| CD206(+) M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, Saeki K, Usui I, Fujisaka S, Tobe K. Nat Commun. 2017 Aug 18;8(1):286. doi: 10.1038/s41467-017-00231-1. PubMed |
| Gcg (CreERT2) knockin mice as a tool for genetic manipulation in pancreatic alpha cells. Shiota C, Prasadan K, Guo P, Fusco J, Xiao X, Gittes GK. Diabetologia. 2017 Dec;60(12):2399-2408. doi: 10.1007/s00125-017-4425-x. Epub 2017 Sep 7. PubMed |
| Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury. Doi T, Ogata T, Yamauchi J, Sawada Y, Tanaka S, Nagao M. J Neurosci. 2017 Oct 25;37(43):10290-10309. doi: 10.1523/JNEUROSCI.1109-17.2017. Epub 2017 Sep 20. PubMed |
| A novel mouse model for tracking the fate of CXCR5-expressing T cells. Takebe T, Sakamoto K, Higami Y, Harada Y. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1642-1647. doi: 10.1016/j.bbrc.2017.12.029. Epub 2017 Dec 6. PubMed |
| Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice. Yoshimura Y, Ida-Tanaka M, Hiramaki T, Goto M, Kamisako T, Eto T, Yagoto M, Kawai K, Takahashi T, Nakayama M, Ito M. Transgenic Res. 2018 Apr;27(2):193-201. doi: 10.1007/s11248-018-0067-0. Epub 2018 Mar 15. PubMed |
Presynaptic Inhibition Selectively Gates Auditory Transmission to the Brainstem Startle Circuit.
Tabor KM, Smith TS, Brown M, Bergeron SA, Briggman KL, Burgess HA.
Curr Biol. 2018 Aug 20;28(16):2527-2535.e8. doi: 10.1016/j.cub.2018.06.020. Epub 2018 Aug 2.
PubMed
Associated Plasmids |
| Genetic Engineering of Human Embryonic Stem Cells for Precise Cell Fate Tracing during Human Lineage Development. Chen Z, Ren X, Xu X, Zhang X, Hui Y, Liu Z, Shi L, Fang Y, Ma L, Liu Y, Terheyden-Keighley D, Liu L, Zhang X. Stem Cell Reports. 2018 Nov 13;11(5):1257-1271. doi: 10.1016/j.stemcr.2018.09.014. Epub 2018 Oct 25. PubMed |
Bright multicolor labeling of neuronal circuits with fluorescent proteins and chemical tags.
Sakaguchi R, Leiwe MN, Imai T.
Elife. 2018 Nov 20;7. pii: 40350. doi: 10.7554/eLife.40350.
PubMed
Associated Plasmids |
| Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRalpha in Adult Brain. Dang TC, Ishii Y, Nguyen V, Yamamoto S, Hamashima T, Okuno N, Nguyen QL, Sang Y, Ohkawa N, Saitoh Y, Shehata M, Takakura N, Fujimori T, Inokuchi K, Mori H, Andrae J, Betsholtz C, Sasahara M. Cell Rep. 2019 Apr 23;27(4):1073-1089.e5. doi: 10.1016/j.celrep.2019.03.084. PubMed |
| Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. Pineault KM, Song JY, Kozloff KM, Lucas D, Wellik DM. Nat Commun. 2019 Jul 18;10(1):3168. doi: 10.1038/s41467-019-11100-4. PubMed |
| Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Wu J, Kung J, Dong J, Chang L, Xie C, Habib A, Hawes S, Yang N, Chen V, Liu Z, Evans R, Liang B, Sun L, Ding J, Yu J, Saez-Atienzar S, Tang B, Khaliq Z, Lin DT, Le W, Cai H. Cell Rep. 2019 Jul 30;28(5):1167-1181.e7. doi: 10.1016/j.celrep.2019.06.095. PubMed |
| How to Choose the Right Inducible Gene Expression System for Mammalian Studies? Kallunki T, Barisic M, Jaattela M, Liu B. Cells. 2019 Jul 30;8(8). pii: cells8080796. doi: 10.3390/cells8080796. PubMed |
| De novo genesis of retinal ganglion cells by targeted expression of Klf4 in vivo. Rocha-Martins M, de Toledo BC, Santos-Franca PL, Oliveira-Valenca VM, Vieira-Vieira CH, Matos-Rodrigues GE, Linden R, Norden C, Martins RAP, Silveira MS. Development. 2019 Aug 21;146(16). pii: dev.176586. doi: 10.1242/dev.176586. PubMed |
An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics.
Allen ME, Zhou W, Thangaraj J, Kyriakakis P, Wu Y, Huang Z, Ho P, Pan Y, Limsakul P, Xu X, Wang Y.
ACS Synth Biol. 2019 Oct 18;8(10):2359-2371. doi: 10.1021/acssynbio.9b00175. Epub 2019 Oct 8.
PubMed
Associated Plasmids |
| Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. Scott RW, Arostegui M, Schweitzer R, Rossi FMV, Underhill TM. Cell Stem Cell. 2019 Dec 5;25(6):797-813.e9. doi: 10.1016/j.stem.2019.11.004. PubMed |
| Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Morikawa K, Furuhashi K, de Sena-Tomas C, Garcia-Garcia AL, Bekdash R, Klein AD, Gallerani N, Yamamoto HE, Park SE, Collins GS, Kawano F, Sato M, Lin CS, Targoff KL, Au E, Salling MC, Yazawa M. Nat Commun. 2020 May 1;11(1):2141. doi: 10.1038/s41467-020-16030-0. PubMed |
| Cell Fate Potential of NG2 Progenitors. Sanchez-Gonzalez R, Bribian A, Lopez-Mascaraque L. Sci Rep. 2020 Jun 18;10(1):9876. doi: 10.1038/s41598-020-66753-9. PubMed |
| beta-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, Xu Y, Yu Z, Liu L, Jiang A, Li W, Abdul MM, Ma G, Li N, Fu X, Lv Y, Jiang M, Tariq M, Kanwal S, Liu H, Xu X, Zhang H, Huang Y, Wang L, Chen S, Babarinde IA, Luo Z, Wang D, Zhou T, Ward C, He M, Ibanez DP, Li Y, Zhou J, Yuan J, Feng Y, Arumugam K, Di Vicino U, Bao X, Wu G, Schambach A, Wang H, Sun H, Gao F, Qin B, Hutchins AP, Doble BW, Hartmann C, Cosma MP, Qin Y, Xu GL, Chen R, Volpe G, Chen L, Hanna JH, Esteban MA. Sci Adv. 2020 Jul 17;6(29):eaba1593. doi: 10.1126/sciadv.aba1593. eCollection 2020 Jul. PubMed |
| SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions. Ishimoto R, Tsuzuki Y, Matsumura T, Kurashige S, Enokitani K, Narimatsu K, Higa M, Sugimoto N, Yoshida K, Fujita M. J Cell Biol. 2021 Jan 4;220(1). pii: 211628. doi: 10.1083/jcb.202003148. PubMed |
| A cell atlas of the chick retina based on single-cell transcriptomics. Yamagata M, Yan W, Sanes JR. Elife. 2021 Jan 4;10. pii: 63907. doi: 10.7554/eLife.63907. PubMed |
| Vasculature-driven stem cell population coordinates tissue scaling in dynamic organs. Ichijo R, Kabata M, Kidoya H, Muramatsu F, Ishibashi R, Abe K, Tsutsui K, Kubo H, Iizuka Y, Kitano S, Miyachi H, Kubota Y, Fujiwara H, Sada A, Yamamoto T, Toyoshima F. Sci Adv. 2021 Feb 10;7(7). pii: 7/7/eabd2575. doi: 10.1126/sciadv.abd2575. Print 2021 Feb. PubMed |
| Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in Glioblastoma. Castellan M, Guarnieri A, Fujimura A, Zanconato F, Battilana G, Panciera T, Sladitschek HL, Contessotto P, Citron A, Grilli A, Romano O, Bicciato S, Fassan M, Porcu E, Rosato A, Cordenonsi M, Piccolo S. Nat Cancer. 2021 Feb;2(2):174-188. doi: 10.1038/s43018-020-00150-z. Epub 2020 Dec 7. PubMed |
| Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue. Kuwano T, Izumi H, Aslam MR, Igarashi Y, Bilal M, Nishimura A, Watanabe Y, Nawaz A, Kado T, Ikuta K, Yamamoto S, Sasahara M, Fujisaka S, Yagi K, Mori H, Tobe K. PLoS One. 2021 Mar 24;16(3):e0248267. doi: 10.1371/journal.pone.0248267. eCollection 2021. PubMed |
| Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation. Fabra-Beser J, Alves Medeiros de Araujo J, Marques-Coelho D, Goff LA, Costa MR, Muller U, Gil-Sanz C. J Neurosci. 2021 Aug 18;41(33):6969-6986. doi: 10.1523/JNEUROSCI.2905-20.2021. Epub 2021 Jul 15. PubMed |
| Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain. Lin CH, Sun Y, Chan CSY, Wu MR, Gu L, Davis AE, Gu B, Zhang W, Tanasa B, Zhong LR, Emerson MM, Chen L, Ding JB, Wang S. J Biol Chem. 2022 Apr;298(4):101674. doi: 10.1016/j.jbc.2022.101674. Epub 2022 Feb 9. PubMed |
| Fate mapping melanoma persister cells through regression and into recurrent disease in adult zebrafish. Travnickova J, Muise S, Wojciechowska S, Brombin A, Zeng Z, Young AIJ, Wyatt C, Patton EE. Dis Model Mech. 2022 Sep 1;15(9):dmm049566. doi: 10.1242/dmm.049566. Epub 2022 Sep 16. PubMed |
| Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, Margulies KB, Choi JC. bioRxiv. 2023 Jun 7:2023.02.14.528563. doi: 10.1101/2023.02.14.528563. Preprint. PubMed |
| Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice. Fujimoto S, Leiwe MN, Aihara S, Sakaguchi R, Muroyama Y, Kobayakawa R, Kobayakawa K, Saito T, Imai T. Dev Cell. 2023 Jul 24;58(14):1221-1236.e7. doi: 10.1016/j.devcel.2023.05.004. Epub 2023 Jun 7. PubMed |
| Multiplex generation and single cell analysis of structural variants in a mammalian genome. Pinglay S, Lalanne JB, Daza RM, Koeppel J, Li X, Lee DS, Shendure J. bioRxiv [Preprint]. 2024 Feb 12:2024.01.22.576756. doi: 10.1101/2024.01.22.576756. PubMed |
| Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. Fowler JL, Zheng SL, Nguyen A, Chen A, Xiong X, Chai T, Chen JY, Karigane D, Banuelos AM, Niizuma K, Kayamori K, Nishimura T, Cromer MK, Gonzalez-Perez D, Mason C, Liu DD, Yilmaz L, Miquerol L, Porteus MH, Luca VC, Majeti R, Nakauchi H, Red-Horse K, Weissman IL, Ang LT, Loh KM. Dev Cell. 2024 May 6;59(9):1110-1131.e22. doi: 10.1016/j.devcel.2024.03.003. Epub 2024 Apr 2. PubMed |
| Simple modeling of familial Alzheimer's disease using human pluripotent stem cell-derived cerebral organoid technology. Choe MS, Yeo HC, Kim JS, Lee J, Lee HJ, Kim HR, Baek KM, Jung NY, Choi M, Lee MY. Stem Cell Res Ther. 2024 Apr 24;15(1):118. doi: 10.1186/s13287-024-03732-1. PubMed |
| Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy. Sikder K, Phillips E, Zhong Z, Wang N, Saunders J, Mothy D, Kossenkov A, Schneider T, Nichtova Z, Csordas G, Margulies KB, Choi JC. Sci Adv. 2024 May 10;10(19):eadh0798. doi: 10.1126/sciadv.adh0798. Epub 2024 May 8. PubMed |
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