p5068 pGEX-6P-1 Brd4 full-length Citations (6)
Originally described in: Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes.You J, Croyle JL, Nishimura A, Ozato K, Howley PM Cell. 2004 Apr 30. 117(3):349-60. PubMed Journal
Articles Citing p5068 pGEX-6P-1 Brd4 full-length
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The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. Lin A, Wang S, Nguyen T, Shire K, Frappier L. J Virol. 2008 Dec;82(24):12009-19. doi: 10.1128/JVI.01680-08. Epub 2008 Oct 15. PubMed |
BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain. Devaiah BN, Lewis BA, Cherman N, Hewitt MC, Albrecht BK, Robey PG, Ozato K, Sims RJ 3rd, Singer DS. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6927-32. doi: 10.1073/pnas.1120422109. Epub 2012 Apr 16. PubMed |
BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin. Devaiah BN, Case-Borden C, Gegonne A, Hsu CH, Chen Q, Meerzaman D, Dey A, Ozato K, Singer DS. Nat Struct Mol Biol. 2016 Jun;23(6):540-8. doi: 10.1038/nsmb.3228. Epub 2016 May 9. PubMed |
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Sdelci S, Lardeau CH, Tallant C, Klepsch F, Klaiber B, Bennett J, Rathert P, Schuster M, Penz T, Fedorov O, Superti-Furga G, Bock C, Zuber J, Huber KV, Knapp S, Muller S, Kubicek S. Nat Chem Biol. 2016 Jul;12(7):504-10. doi: 10.1038/nchembio.2080. Epub 2016 May 9. PubMed |
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. PubMed |
BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation. Musa RE, Lester KL, Quickstad G, Vardabasso S, Shumate TV, Salcido RT, Ge K, Shpargel KB. Development. 2024 Jan 15;151(2):dev202110. doi: 10.1242/dev.202110. Epub 2024 Jan 24. PubMed |
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