p4947 pcDNA4c hBrd4 full-length Citations (12)

Originally described in: Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes.
You J, Croyle JL, Nishimura A, Ozato K, Howley PM Cell. 2004 Apr 30. 117(3):349-60. PubMed Journal

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Articles Citing p4947 pcDNA4c hBrd4 full-length

Articles
Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation. Ai N, Hu X, Ding F, Yu B, Wang H, Lu X, Zhang K, Li Y, Han A, Lin W, Liu R, Chen R. Nucleic Acids Res. 2011 Dec;39(22):9592-604. doi: 10.1093/nar/gkr698. Epub 2011 Sep 2. PubMed
Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer. Rodriguez RM, Huidobro C, Urdinguio RG, Mangas C, Soldevilla B, Dominguez G, Bonilla F, Fernandez AF, Fraga MF. J Mol Med (Berl). 2012 May;90(5):587-95. doi: 10.1007/s00109-011-0837-0. Epub 2011 Nov 27. PubMed
Role of BRD4 in hematopoietic differentiation of embryonic stem cells. Rodriguez RM, Suarez-Alvarez B, Salvanes R, Huidobro C, Torano EG, Garcia-Perez JL, Lopez-Larrea C, Fernandez AF, Bueno C, Menendez P, Fraga MF. Epigenetics. 2014 Apr;9(4):566-78. doi: 10.4161/epi.27711. Epub 2014 Jan 20. PubMed
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming. Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Cell Stem Cell. 2014 Nov 6;15(5):574-88. doi: 10.1016/j.stem.2014.09.018. Epub 2014 Oct 9. PubMed
Key determinants of target DNA recognition by retroviral intasomes. Serrao E, Ballandras-Colas A, Cherepanov P, Maertens GN, Engelman AN. Retrovirology. 2015 Apr 30;12:39. doi: 10.1186/s12977-015-0167-3. PubMed
BRD4 Regulates EZH2 Transcription through Upregulation of C-MYC and Represents a Novel Therapeutic Target in Bladder Cancer. Wu X, Liu D, Tao D, Xiang W, Xiao X, Wang M, Wang L, Luo G, Li Y, Zeng F, Jiang G. Mol Cancer Ther. 2016 May;15(5):1029-42. doi: 10.1158/1535-7163.MCT-15-0750. Epub 2016 Mar 3. PubMed
Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Hao J, Yang Z, Wang L, Zhang Y, Shu Y, Jiang L, Hu Y, Lv W, Dong P, Liu Y. Int J Oncol. 2017 Sep;51(3):823-831. doi: 10.3892/ijo.2017.4081. Epub 2017 Jul 27. PubMed
Brd4's Bromodomains Mediate Histone H3 Acetylation and Chromatin Remodeling in Pluripotent Cells through P300 and Brg1. Wu T, Kamikawa YF, Donohoe ME. Cell Rep. 2018 Nov 13;25(7):1756-1771. doi: 10.1016/j.celrep.2018.10.003. PubMed
Inhibition of BRD4 attenuates transverse aortic constriction- and TGF-beta-induced endothelial-mesenchymal transition and cardiac fibrosis. Song S, Liu L, Yu Y, Zhang R, Li Y, Cao W, Xiao Y, Fang G, Li Z, Wang X, Wang Q, Zhao X, Chen L, Wang Y, Wang Q. J Mol Cell Cardiol. 2019 Feb;127:83-96. doi: 10.1016/j.yjmcc.2018.12.002. Epub 2018 Dec 7. PubMed
BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo. Liu S, Li F, Pan L, Yang Z, Shu Y, Lv W, Dong P, Gong W. Cancer Sci. 2019 Aug;110(8):2493-2506. doi: 10.1111/cas.14102. Epub 2019 Jul 11. PubMed
Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Wessel SR, Mohni KN, Luzwick JW, Dungrawala H, Cortez D. Cell Rep. 2019 Sep 24;28(13):3497-3509.e4. doi: 10.1016/j.celrep.2019.08.051. PubMed
Yy1 regulates Senp1 contributing to AMPA receptor GluR1 expression following neuronal depolarization. Wu T, Donohoe ME. J Biomed Sci. 2019 Oct 20;26(1):79. doi: 10.1186/s12929-019-0582-1. PubMed

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