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pAdEasy Flag GCN5 Citations (6)

Originally described in: GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha.
Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A, Puigserver P Cell Metab. 2006 Jun . 3(6):429-38.
PubMed Journal

Articles Citing pAdEasy Flag GCN5

Articles
Muscle Wasting in Fasting Requires Activation of NF-kappaB and Inhibition of AKT/Mechanistic Target of Rapamycin (mTOR) by the Protein Acetylase, GCN5. Lee D, Goldberg AL. J Biol Chem. 2015 Dec 18;290(51):30269-79. doi: 10.1074/jbc.M115.685164. Epub 2015 Oct 29. PubMed
Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity. Park JM, Kim TH, Jo SH, Kim MY, Ahn YH. Sci Rep. 2015 Dec 1;5:17395. doi: 10.1038/srep17395. PubMed
Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development. Dai J, Bercury KK, Jin W, Macklin WB. J Neurosci. 2015 Dec 2;35(48):15875-93. doi: 10.1523/JNEUROSCI.0882-15.2015. PubMed
Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, Zhuang S, Tan X, Fu Q, Xie L, Li Z, Yuan Z. Cell Death Dis. 2017 Jan 26;8(1):e2570. doi: 10.1038/cddis.2016.465. PubMed
Real-time observation of light-controlled transcription in living cells. Rademacher A, Erdel F, Trojanowski J, Schumacher S, Rippe K. J Cell Sci. 2017 Dec 15;130(24):4213-4224. doi: 10.1242/jcs.205534. Epub 2017 Nov 9. PubMed

Associated Plasmids

GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression. Addicks GC, Zhang H, Ryu D, Vasam G, Green AE, Marshall PL, Patel S, Kang BE, Kim D, Katsyuba E, Williams EG, Renaud JM, Auwerx J, Menzies KJ. J Cell Biol. 2022 Feb 7;221(2):e202104022. doi: 10.1083/jcb.202104022. Epub 2022 Jan 13. PubMed

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