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pCMV-T7-ABEmax(7.10)-SpG-P2A-EGFP (RTW4562) Citations (6)

Originally described in: Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.
Walton RT, Christie KA, Whittaker MN, Kleinstiver BP Science. 2020 Apr 17;368(6488):290-296. doi: 10.1126/science.aba8853. Epub 2020 Mar 26.
PubMed Journal

Articles Citing pCMV-T7-ABEmax(7.10)-SpG-P2A-EGFP (RTW4562)

Articles
Mutation-specific reporter for optimization and enrichment of prime editing. Schene IF, Joore IP, Baijens JHL, Stevelink R, Kok G, Shehata S, Ilcken EF, Nieuwenhuis ECM, Bolhuis DP, van Rees RCM, Spelier SA, van der Doef HPJ, Beekman JM, Houwen RHJ, Nieuwenhuis EES, Fuchs SA. Nat Commun. 2022 Mar 1;13(1):1028. doi: 10.1038/s41467-022-28656-3. PubMed

Associated Plasmids

Correction of DMD in human iPSC-derived cardiomyocytes by base-editing-induced exon skipping. Wang P, Li H, Zhu M, Han RY, Guo S, Han R. Mol Ther Methods Clin Dev. 2022 Dec 2;28:40-50. doi: 10.1016/j.omtm.2022.11.010. eCollection 2023 Mar 9. PubMed
Direct measurement of engineered cancer mutations and their transcriptional phenotypes in single cells. Kim HS, Grimes SM, Chen T, Sathe A, Lau BT, Hwang GH, Bae S, Ji HP. Nat Biotechnol. 2023 Sep 11. doi: 10.1038/s41587-023-01949-8. PubMed
The FXR1 network acts as signaling scaffold for actomyosin remodeling. Chen X, Fansler MM, Janjoš U, Ule J, Mayr C. Cell. 5 August 2024. doi: 10.1016/j.cell.2024.07.015. PubMed

Associated Plasmids

Correction of human nonsense mutation via adenine base editing for Duchenne muscular dystrophy treatment in mouse. Jin M, Lin J, Li H, Li Z, Yang D, Wang Y, Yu Y, Shao Z, Chen L, Wang Z, Zhang Y, Zhang X, Wang N, Xu C, Yang H, Chen WJ, Li G. Mol Ther Nucleic Acids. 2024 Mar 6;35(2):102165. doi: 10.1016/j.omtn.2024.102165. eCollection 2024 Jun 11. PubMed
Context base editing for splice correction of IVSI-110 beta-thalassemia. Naiisseh B, Papasavva PL, Papaioannou NY, Tomazou M, Koniali L, Felekis X, Constantinou CG, Sitarou M, Christou S, Kleanthous M, Lederer CW, Patsali P. Mol Ther Nucleic Acids. 2024 Mar 30;35(2):102183. doi: 10.1016/j.omtn.2024.102183. eCollection 2024 Jun 11. PubMed

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