ABE8e(TadA-8e V106W) Citations (9)
Originally described in: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity.Richter MF, Zhao KT, Eton E, Lapinaite A, Newby GA, Thuronyi BW, Wilson C, Koblan LW, Zeng J, Bauer DE, Doudna JA, Liu DR Nat Biotechnol. 2020 Jul;38(7):883-891. doi: 10.1038/s41587-020-0453-z. Epub 2020 Mar 16. PubMed Journal
Articles Citing ABE8e(TadA-8e V106W)
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| Adenine base editor engineering reduces editing of bystander cytosines. Jeong YK, Lee S, Hwang GH, Hong SA, Park SE, Kim JS, Woo JS, Bae S. Nat Biotechnol. 2021 Nov;39(11):1426-1433. doi: 10.1038/s41587-021-00943-2. Epub 2021 Jul 1. PubMed |
| Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin. Ravi NS, Wienert B, Wyman SK, Bell HW, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BP, Devaraju N, Rajendiran V, Syedbasha N, Pai AA, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, DeWitt MA, Crossley M, Corn JE, Mohankumar KM. Elife. 2022 Feb 11;11. pii: 65421. doi: 10.7554/eLife.65421. PubMed |
Mutation-specific reporter for optimization and enrichment of prime editing.
Schene IF, Joore IP, Baijens JHL, Stevelink R, Kok G, Shehata S, Ilcken EF, Nieuwenhuis ECM, Bolhuis DP, van Rees RCM, Spelier SA, van der Doef HPJ, Beekman JM, Houwen RHJ, Nieuwenhuis EES, Fuchs SA.
Nat Commun. 2022 Mar 1;13(1):1028. doi: 10.1038/s41467-022-28656-3.
PubMed
Associated Plasmids |
| Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System. Devaraju N, Rajendiran V, Ravi NS, Mohankumar KM. Methods Mol Biol. 2022;2429:307-331. doi: 10.1007/978-1-0716-1979-7_20. PubMed |
| Correction of DMD in human iPSC-derived cardiomyocytes by base-editing-induced exon skipping. Wang P, Li H, Zhu M, Han RY, Guo S, Han R. Mol Ther Methods Clin Dev. 2022 Dec 2;28:40-50. doi: 10.1016/j.omtm.2022.11.010. eCollection 2023 Mar 9. PubMed |
| Single-swap editing for the correction of common Duchenne muscular dystrophy mutations. Chai AC, Chemello F, Li H, Nishiyama T, Chen K, Zhang Y, Sanchez-Ortiz E, Alomar A, Xu L, Liu N, Bassel-Duby R, Olson EN. Mol Ther Nucleic Acids. 2023 Apr 19;32:522-535. doi: 10.1016/j.omtn.2023.04.009. eCollection 2023 Jun 13. PubMed |
| CRISPR-Cas9 base editing of pathogenic CaMKIIdelta improves cardiac function in a humanized mouse model. Lebek S, Caravia XM, Straub LG, Alzhanov D, Tan W, Li H, McAnally JR, Chen K, Xu L, Scherer PE, Liu N, Bassel-Duby R, Olson EN. J Clin Invest. 2024 Jan 2;134(1):e175164. doi: 10.1172/JCI175164. PubMed |
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.
Cho SI, Lim K, Hong S, Lee J, Kim A, Lim CJ, Ryou S, Lee JM, Mok YG, Chung E, Kim S, Han S, Cho SM, Kim J, Kim EK, Nam KH, Oh Y, Choi M, An TH, Oh KJ, Lee S, Lee H, Kim JS.
Cell. 2024 Jan 4;187(1):95-109.e26. doi: 10.1016/j.cell.2023.11.035.
PubMed
Associated Plasmids |
| Precise correction of a spectrum of beta-thalassemia mutations in coding and non-coding regions by base editors. Prasad K, Devaraju N, George A, Ravi NS, Paul J, Mahalingam G, Rajendiran V, Panigrahi L, Venkatesan V, Lakhotiya K, Periyasami Y, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Velayudhan SR, Newby GA, Marepally S, Srivastava A, Mohankumar KM. Mol Ther Nucleic Acids. 2024 May 3;35(2):102205. doi: 10.1016/j.omtn.2024.102205. eCollection 2024 Jun 11. PubMed |
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