HDAC3 Flag Citations (27)
Originally described in: Characterization of a human RPD3 ortholog, HDAC3.Emiliani S, Fischle W, Van Lint C, Al-Abed Y, Verdin E Proc Natl Acad Sci U S A. 1998 Mar 17. 95(6):2795-800. PubMed Journal
Articles Citing HDAC3 Flag
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| Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes. Pillai VB, Sundaresan NR, Samant SA, Wolfgeher D, Trivedi CM, Gupta MP. Mol Cell Biol. 2011 Jun;31(11):2349-63. doi: 10.1128/MCB.01205-10. Epub 2011 Mar 28. PubMed |
| Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells. Hsu YF, Sheu JR, Lin CH, Yang DS, Hsiao G, Ou G, Chiu PT, Huang YH, Kuo WH, Hsu MJ. Biochim Biophys Acta. 2012 Feb;1820(2):104-15. doi: 10.1016/j.bbagen.2011.11.011. Epub 2011 Dec 1. PubMed |
| The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter. Darlyuk-Saadon I, Weidenfeld-Baranboim K, Yokoyama KK, Hai T, Aronheim A. Biochim Biophys Acta. 2012 Nov-Dec;1819(11-12):1142-53. doi: 10.1016/j.bbagrm.2012.09.005. Epub 2012 Sep 16. PubMed |
| Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Isaacs JT, Antony L, Dalrymple SL, Brennen WN, Gerber S, Hammers H, Wissing M, Kachhap S, Luo J, Xing L, Bjork P, Olsson A, Bjork A, Leanderson T. Cancer Res. 2013 Feb 15;73(4):1386-99. doi: 10.1158/0008-5472.CAN-12-2730. Epub 2012 Nov 13. PubMed |
| Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade. Chang HL, Chen CY, Hsu YF, Kuo WS, Ou G, Chiu PT, Huang YH, Hsu MJ. Biochim Biophys Acta. 2013 Aug;1830(8):4053-64. doi: 10.1016/j.bbagen.2013.04.011. Epub 2013 Apr 12. PubMed |
| Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomes. Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch-Klupp I, Bilban M, Brostjan C. PLoS One. 2013 Oct 11;8(10):e76845. doi: 10.1371/journal.pone.0076845. eCollection 2013. PubMed |
| Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. Shin HJ, DeCotiis J, Giron M, Palmeri D, Lukac DM. J Virol. 2014 Jan;88(2):1281-92. doi: 10.1128/JVI.02665-13. Epub 2013 Nov 13. PubMed |
| Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome. Bjornsson HT, Benjamin JS, Zhang L, Weissman J, Gerber EE, Chen YC, Vaurio RG, Potter MC, Hansen KD, Dietz HC. Sci Transl Med. 2014 Oct 1;6(256):256ra135. doi: 10.1126/scitranslmed.3009278. PubMed |
| E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro. Rahman S, Housein Z, Dabrowska A, Mayan MD, Boobis AR, Hajji N. Environ Health Perspect. 2015 May;123(5):484-92. doi: 10.1289/ehp.1408302. Epub 2015 Jan 9. PubMed |
| The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death. Huang YH, Huang SW, Hsu YF, Ou G, Huang WJ, Hsu MJ. Sci Rep. 2015 Oct 29;5:15900. doi: 10.1038/srep15900. PubMed |
| A SUMO-acetyl switch in PXR biology. Cui W, Sun M, Zhang S, Shen X, Galeva N, Williams TD, Staudinger JL. Biochim Biophys Acta. 2016 Feb 12. pii: S1874-9399(16)30030-X. doi: 10.1016/j.bbagrm.2016.02.008. PubMed |
| Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade. Yen CS, Chen JC, Chang YF, Hsu YF, Chiu PT, Shiue C, Chuang YF, Ou G, Hsu MJ. Sci Rep. 2016 Apr 28;6:25082. doi: 10.1038/srep25082. PubMed |
| Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6. Liu HM, Jiang F, Loo YM, Hsu S, Hsiang TY, Marcotrigiano J, Gale M Jr. EBioMedicine. 2016 Jul;9:195-206. doi: 10.1016/j.ebiom.2016.06.015. Epub 2016 Jun 11. PubMed |
Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC.
Kwon DY, Zhao YT, Lamonica JM, Zhou Z.
Nat Commun. 2017 May 12;8:15315. doi: 10.1038/ncomms15315.
PubMed
Associated Plasmids |
| G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Wang YF, Zhang J, Su Y, Shen YY, Jiang DX, Hou YY, Geng MY, Ding J, Chen Y. Nat Commun. 2017 Aug 17;8(1):274. doi: 10.1038/s41467-017-00350-9. PubMed |
| LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Mirza AN, McKellar SA, Urman NM, Brown AS, Hollmig T, Aasi SZ, Oro AE. Cell. 2019 Jan 10;176(1-2):198-212.e15. doi: 10.1016/j.cell.2018.10.054. Epub 2018 Nov 29. PubMed |
| Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1. Pfister JA, Ma C, D'Mello SR. PLoS One. 2019 Apr 11;14(4):e0215208. doi: 10.1371/journal.pone.0215208. eCollection 2019. PubMed |
| Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling. Ho M, Chen T, Liu J, Dowling P, Hideshima T, Zhang L, Morelli E, Camci-Unal G, Wu X, Tai YT, Wen K, Samur M, Schlossman RL, Mazitschek R, Kavanagh EL, Lindsay S, Harada T, McCann A, Anderson KC, O'Gorman P, Bianchi G. Leukemia. 2019 May 29. pii: 10.1038/s41375-019-0493-x. doi: 10.1038/s41375-019-0493-x. PubMed |
| Mdm2 is required for HDAC3 monoubiquitination and stability. Choi YM, An S, Bae S, Jung JH. Biochem Biophys Res Commun. 2019 Sep 17;517(2):353-358. doi: 10.1016/j.bbrc.2019.07.052. Epub 2019 Jul 26. PubMed |
| Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Sci Rep. 2019 Nov 12;9(1):16565. doi: 10.1038/s41598-019-53049-w. PubMed |
| Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. Nagareddy B, Khan A, Kim H. J Biol Chem. 2020 Oct 2;295(40):13887-13901. doi: 10.1074/jbc.RA120.015288. Epub 2020 Aug 6. PubMed |
| Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis. Taha TY, Anirudhan V, Limothai U, Loeb DD, Petukhov PA, McLachlan A. PLoS Pathog. 2020 Aug 21;16(8):e1008802. doi: 10.1371/journal.ppat.1008802. eCollection 2020 Aug. PubMed |
| Activation of Tripartite Motif Containing 63 Expression by Transcription Factor EB and Transcription Factor Binding to Immunoglobulin Heavy Chain Enhancer 3 Is Regulated by Protein Kinase D and Class IIa Histone Deacetylases. Pablo Tortola C, Fielitz B, Li Y, Rudebusch J, Luft FC, Fielitz J. Front Physiol. 2021 Jan 13;11:550506. doi: 10.3389/fphys.2020.550506. eCollection 2020. PubMed |
| ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses. Bruce JW, Bracken M, Evans E, Sherer N, Ahlquist P. PLoS Pathog. 2021 Feb 26;17(2):e1009364. doi: 10.1371/journal.ppat.1009364. eCollection 2021 Feb. PubMed |
| Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression. Schmitt HM, Fehrman RL, Maes ME, Yang H, Guo LW, Schlamp CL, Pelzel HR, Nickells RW. Invest Ophthalmol Vis Sci. 2021 Aug 2;62(10):14. doi: 10.1167/iovs.62.10.14. PubMed |
| Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Elsasser SJ, Skodras AA, Gloeckner CJ, Buratti E, Neumann M, Kahle PJ. Nat Commun. 2022 Mar 9;13(1):1223. doi: 10.1038/s41467-022-28822-7. PubMed |
| BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps. Maes ME, Donahue RJ, Schlamp CL, Marola OJ, Libby RT, Nickells R. Res Sq. 2023 May 15:rs.3.rs-2846437. doi: 10.21203/rs.3.rs-2846437/v1. Preprint. PubMed |
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