SIRT5 Flag Citations (14)

Originally described in: The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E Mol Cell. 2003 Feb . 11(2):437-44. PubMed Journal

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Articles Citing SIRT5 Flag

Articles
The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination. Ronnebaum SM, Wu Y, McDonough H, Patterson C. Mol Cell Biol. 2013 Nov;33(22):4461-72. doi: 10.1128/MCB.00480-13. Epub 2013 Sep 16. PubMed
SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Samant SA, Zhang HJ, Hong Z, Pillai VB, Sundaresan NR, Wolfgeher D, Archer SL, Chan DC, Gupta MP. Mol Cell Biol. 2014 Mar;34(5):807-19. doi: 10.1128/MCB.01483-13. Epub 2013 Dec 16. PubMed
SIRT5 is under the control of PGC-1alpha and AMPK and is involved in regulation of mitochondrial energy metabolism. Buler M, Aatsinki SM, Izzi V, Uusimaa J, Hakkola J. FASEB J. 2014 Jul;28(7):3225-37. doi: 10.1096/fj.13-245241. Epub 2014 Mar 31. PubMed
SIRT5 regulation of ammonia-induced autophagy and mitophagy. Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, Steegborn C, Nowak T, Schutkowski M, Pellegrini L, Sansone L, Villanova L, Runci A, Pucci B, Morgante E, Fini M, Mai A, Russo MA, Tafani M. Autophagy. 2015;11(2):253-70. doi: 10.1080/15548627.2015.1009778. PubMed
Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Mol Cell Biol. 2016 Sep 12;36(19):2487-502. doi: 10.1128/MCB.00342-16. Print 2016 Oct 1. PubMed
Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation. Guedouari H, Daigle T, Scorrano L, Hebert-Chatelain E. Biochim Biophys Acta. 2017 Jan;1864(1):169-176. doi: 10.1016/j.bbamcr.2016.10.015. Epub 2016 Nov 15. PubMed
SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta MP, Singh M, Sundaresan NR. Elife. 2018 Mar 5;7. pii: 32952. doi: 10.7554/eLife.32952. PubMed
APC/C CDH1 ubiquitinates IDH2 contributing to ROS increase in mitosis. Lambhate S, Bhattacharjee D, Jain N. Cell Signal. 2021 Oct;86:110087. doi: 10.1016/j.cellsig.2021.110087. Epub 2021 Jul 13. PubMed
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Shimizu K, Gi M, Suzuki S, North BJ, Watahiki A, Fukumoto S, Asara JM, Tokunaga F, Wei W, Inuzuka H. Cell Rep. 2021 Nov 9;37(6):109988. doi: 10.1016/j.celrep.2021.109988. PubMed
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Elsasser SJ, Skodras AA, Gloeckner CJ, Buratti E, Neumann M, Kahle PJ. Nat Commun. 2022 Mar 9;13(1):1223. doi: 10.1038/s41467-022-28822-7. PubMed
Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD(+) and SIRT3. Masgras I, Cannino G, Ciscato F, Sanchez-Martin C, Darvishi FB, Scantamburlo F, Pizzi M, Menga A, Fregona D, Castegna A, Rasola A. Cell Death Differ. 2022 Apr 7. pii: 10.1038/s41418-022-00991-4. doi: 10.1038/s41418-022-00991-4. PubMed
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin. Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP. Sci Transl Med. 2022 May 25;14(646):eabn4772. doi: 10.1126/scitranslmed.abn4772. Epub 2022 May 25. PubMed
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase. Bolding JE, Martin-Gago P, Rajabi N, Gamon LF, Hansen TN, Bartling CRO, Stromgaard K, Davies MJ, Olsen CA. Angew Chem Int Ed Engl. 2022 Nov 21;61(47):e202204565. doi: 10.1002/anie.202204565. Epub 2022 Oct 21. PubMed
Multifunctional activity-based chemical probes for sirtuins. Sharma C, Donu D, Curry AM, Barton E, Cen Y. RSC Adv. 2023 Apr 14;13(17):11771-11781. doi: 10.1039/d3ra02133e. eCollection 2023 Apr 11. PubMed

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