pLS-SceI Citations (9)

Originally described in: lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements.
Gordon MG, Inoue F, Martin B, Schubach M, Agarwal V, Whalen S, Feng S, Zhao J, Ashuach T, Ziffra R, Kreimer A, Georgakopoulous-Soares I, Yosef N, Ye CJ, Pollard KS, Shendure J, Kircher M, Ahituv N Nat Protoc. 2020 Aug;15(8):2387-2412. doi: 10.1038/s41596-020-0333-5. Epub 2020 Jul 8. PubMed Journal

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Articles Citing pLS-SceI

Articles
lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Gordon MG, Inoue F, Martin B, Schubach M, Agarwal V, Whalen S, Feng S, Zhao J, Ashuach T, Ziffra R, Kreimer A, Georgakopoulous-Soares I, Yosef N, Ye CJ, Pollard KS, Shendure J, Kircher M, Ahituv N. Nat Protoc. 2020 Aug;15(8):2387-2412. doi: 10.1038/s41596-020-0333-5. Epub 2020 Jul 8. PubMed Associated Plasmids pLS-SV40-mP-EGFP pLS-SceI
The cis-regulatory effects of modern human-specific variants. Weiss CV, Harshman L, Inoue F, Fraser HB, Petrov DA, Ahituv N, Gokhman D. Elife. 2021 Apr 22;10. pii: 63713. doi: 10.7554/eLife.63713. PubMed
Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. Kreimer A, Ashuach T, Inoue F, Khodaverdian A, Deng C, Yosef N, Ahituv N. Nat Commun. 2022 Mar 21;13(1):1504. doi: 10.1038/s41467-022-28659-0. PubMed
Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter Assays. Koesterich J, An JY, Inoue F, Sohota A, Ahituv N, Sanders SJ, Kreimer A. Int J Mol Sci. 2023 Feb 9;24(4):3509. doi: 10.3390/ijms24043509. PubMed
Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types. Agarwal V, Inoue F, Schubach M, Martin BK, Dash PM, Zhang Z, Sohota A, Noble WS, Yardimci GG, Kircher M, Shendure J, Ahituv N. bioRxiv. 2023 Mar 6:2023.03.05.531189. doi: 10.1101/2023.03.05.531189. Preprint. PubMed
Transcription factor binding site orientation and order are major drivers of gene regulatory activity. Georgakopoulos-Soares I, Deng C, Agarwal V, Chan CSY, Zhao J, Inoue F, Ahituv N. Nat Commun. 2023 Apr 22;14(1):2333. doi: 10.1038/s41467-023-37960-5. PubMed
Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids. Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, Ahituv N, Abyzov A, Vaccarino FM. bioRxiv [Preprint]. 2023 Aug 14:2023.08.14.553170. doi: 10.1101/2023.08.14.553170. PubMed
Massively parallel reporter assays and mouse transgenic assays provide complementary information about neuronal enhancer activity. Kosicki M, Cintron DL, Page NF, Georgakopoulos-Soares I, Akiyama JA, Plajzer-Frick I, Novak CS, Kato M, Hunter RD, von Maydell K, Barton S, Godfrey P, Beckman E, Sanders SJ, Pennacchio LA, Ahituv N. bioRxiv [Preprint]. 2024 Apr 23:2024.04.22.590634. doi: 10.1101/2024.04.22.590634. PubMed
Emergence of activation or repression in transcriptional control under a fixed molecular context. Martinez-Corral R, Friedrich D, Fromel R, Velten L, Gunawardena J, DePace AH. bioRxiv [Preprint]. 2024 Jun 2:2024.05.29.596388. doi: 10.1101/2024.05.29.596388. PubMed

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