pMH0006 Citations (7)
Originally described in: Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M J Biol Chem. 2019 Oct 2. pii: RA119.009432. doi: 10.1074/jbc.RA119.009432. PubMed Journal
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Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Elife. 2021 May 26;10. pii: 67624. doi: 10.7554/eLife.67624. PubMed |
Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function. Carling PJ, Ryan BJ, McGuinness W, Kataria S, Humble SW, Milde S, Duce JA, Kapadia N, Zuercher WJ, Davis JB, Di Daniel E, Wade-Martins R. Autophagy. 2023 Feb;19(2):692-705. doi: 10.1080/15548627.2022.2095834. Epub 2022 Jul 25. PubMed |
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, Kampmann M, Weissman JS, Jost M.
eLife. 2022 Dec 28;11:e81856. doi: 10.7554/eLife.81856.
PubMed
Associated Plasmids |
A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.
Guna A, Page KR, Replogle JM, Esantsi TK, Wang ML, Weissman JS, Voorhees RM.
BMC Genomics. 2023 Oct 30;24(1):651. doi: 10.1186/s12864-023-09754-y.
PubMed
Associated Plasmids |
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus. Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H. Nat Cell Biol. 2023 Jun;25(6):892-903. doi: 10.1038/s41556-023-01141-9. Epub 2023 May 8. PubMed |
A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER. Pleiner T, Hazu M, Pinton Tomaleri G, Nguyen VN, Januszyk K, Voorhees RM. J Cell Biol. 2023 Aug 7;222(8):e202212007. doi: 10.1083/jcb.202212007. Epub 2023 May 18. PubMed |
Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis Lesions and Its Involvement in Oligodendroglial Stress Responses. Zhan J, Gao Y, Heinig L, Beecken M, Huo Y, Zhang W, Wang P, Wei T, Tian R, Han W, Yu ACH, Kipp M, Kaddatz H. Cells. 2023 Aug 17;12(16):2085. doi: 10.3390/cells12162085. PubMed |
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