pCDNA3-Flag MKK6(K82A) Citations (12)

Originally described in: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ Mol Cell Biol. 1996 Mar . 16(3):1247-55. PubMed

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Articles Citing pCDNA3-Flag MKK6(K82A)

Articles
GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes. Tsuchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, Marcu KB, Komiya S, Ijiri K, Goldring MB. J Biol Chem. 2010 Mar 12;285(11):8395-407. doi: 10.1074/jbc.M109.038638. Epub 2010 Jan 4. PubMed
Thermogenic activation induces FGF21 expression and release in brown adipose tissue. Hondares E, Iglesias R, Giralt A, Gonzalez FJ, Giralt M, Mampel T, Villarroya F. J Biol Chem. 2011 Apr 15;286(15):12983-90. doi: 10.1074/jbc.M110.215889. Epub 2011 Feb 13. PubMed
Gestational diabetes induces alterations in the function of neonatal endothelial colony-forming cells. Blue EK, DiGiuseppe R, Derr-Yellin E, Acosta JC, Pay SL, Hanenberg H, Schellinger MM, Quinney SK, Mund JA, Case J, Haneline LS. Pediatr Res. 2014 Feb;75(2):266-72. doi: 10.1038/pr.2013.224. Epub 2013 Nov 14. PubMed
FGF21 expression and release in muscle cells: involvement of MyoD and regulation by mitochondria-driven signalling. Ribas F, Villarroya J, Hondares E, Giralt M, Villarroya F. Biochem J. 2014 Oct 15;463(2):191-9. doi: 10.1042/BJ20140403. PubMed
Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis. Lawan A, Zhang L, Gatzke F, Min K, Jurczak MJ, Al-Mutairi M, Richter P, Camporez JP, Couvillon A, Pesta D, Roth Flach RJ, Shulman GI, Bennett AM. Mol Cell Biol. 2015 Jan;35(1):26-40. doi: 10.1128/MCB.00503-14. Epub 2014 Oct 13. PubMed
p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility. Li L, Gao G, Shankar J, Joshi B, Foster LJ, Nabi IR. Mol Biol Cell. 2015 Nov 1;26(21):3828-40. doi: 10.1091/mbc.E15-02-0120. Epub 2015 Sep 2. PubMed
The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes. Quesada-Lopez T, Cereijo R, Turatsinze JV, Planavila A, Cairo M, Gavalda-Navarro A, Peyrou M, Moure R, Iglesias R, Giralt M, Eizirik DL, Villarroya F. Nat Commun. 2016 Nov 17;7:13479. doi: 10.1038/ncomms13479. PubMed
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. Xiong G, Hindi SM, Mann AK, Gallot YS, Bohnert KR, Cavener DR, Whittemore SR, Kumar A. Elife. 2017 Mar 23;6. doi: 10.7554/eLife.22871. PubMed
Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells. Basken J, Stuart SA, Kavran AJ, Lee T, Ebmeier CC, Old WM, Ahn NG. Mol Cell Proteomics. 2018 Apr;17(4):550-564. doi: 10.1074/mcp.RA117.000335. Epub 2017 Dec 18. PubMed
Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling. Rahman SMT, Zhou W, Deiters A, Haugh JM. J Biol Chem. 2020 Jun 19;295(25):8494-8504. doi: 10.1074/jbc.RA119.012079. Epub 2020 May 5. PubMed
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Bruning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschop MH, Muller TD. Nat Commun. 2020 May 8;11(1):2306. doi: 10.1038/s41467-020-16230-8. PubMed
Fasting-Induced Upregulation of MKP-1 Modulates the Hepatic Response to Feeding. Sellers J, Brooks A, Fernando S, Westenberger G, Junkins S, Smith S, Min K, Lawan A. Nutrients. 2021 Nov 4;13(11). pii: nu13113941. doi: 10.3390/nu13113941. PubMed

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