pLKO.1 neo Citations (44)
Originally described in: Stewart Lab PlasmidsUnpublished
Articles Citing pLKO.1 neo
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| Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Tang YL, Zhu W, Cheng M, Chen L, Zhang J, Sun T, Kishore R, Phillips MI, Losordo DW, Qin G. Circ Res. 2009 May 22;104(10):1209-16. doi: 10.1161/CIRCRESAHA.109.197723. Epub 2009 Apr 30. PubMed |
| O2 regulates stem cells through Wnt/beta-catenin signalling. Mazumdar J, O'Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, Simon MC. Nat Cell Biol. 2010 Oct;12(10):1007-13. doi: 10.1038/ncb2102. Epub 2010 Sep 19. PubMed |
| Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic beta cell death. Bartolome A, Guillen C, Benito M. Autophagy. 2012 Dec;8(12):1757-68. doi: 10.4161/auto.21994. Epub 2012 Sep 5. PubMed |
| Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer. Burns TF, Dobromilskaya I, Murphy SC, Gajula RP, Thiyagarajan S, Chatley SN, Aziz K, Cho YJ, Tran PT, Rudin CM. Mol Cancer Res. 2013 Apr;11(4):329-38. doi: 10.1158/1541-7786.MCR-12-0456. Epub 2013 Jan 30. PubMed |
| Pancreatic beta-cell failure mediated by mTORC1 hyperactivity and autophagic impairment. Bartolome A, Kimura-Koyanagi M, Asahara S, Guillen C, Inoue H, Teruyama K, Shimizu S, Kanno A, Garcia-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y. Diabetes. 2014 Sep;63(9):2996-3008. doi: 10.2337/db13-0970. Epub 2014 Apr 16. PubMed |
| Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress. Lee S, Min Kim S, Dotimas J, Li L, Feener EP, Baldus S, Myers RB, Chutkow WA, Patwari P, Yoshioka J, Lee RT. EMBO Mol Med. 2014 May 19;6(6):732-43. doi: 10.15252/emmm.201302561. PubMed |
| Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer. Rodrigues LU, Rider L, Nieto C, Romero L, Karimpour-Fard A, Loda M, Lucia MS, Wu M, Shi L, Cimic A, Sirintrapun SJ, Nolley R, Pac C, Chen H, Peehl DM, Xu J, Liu W, Costello JC, Cramer SD. Cancer Res. 2015 Mar 15;75(6):1021-34. doi: 10.1158/0008-5472.CAN-14-1596. PubMed |
| TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy. Garcia-Aguilar A, Guillen C, Nellist M, Bartolome A, Benito M. Biochim Biophys Acta. 2016 Nov;1863(11):2658-2667. doi: 10.1016/j.bbamcr.2016.08.006. Epub 2016 Aug 16. PubMed |
| Hemidesmosomal linker proteins regulate cell motility, invasion and tumorigenicity in oral squamous cell carcinoma derived cells. Chaudhari PR, Charles SE, D'Souza ZC, Vaidya MM. Exp Cell Res. 2017 Nov 15;360(2):125-137. doi: 10.1016/j.yexcr.2017.08.034. Epub 2017 Sep 1. PubMed |
| ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/CDKN2A regulatory axis. Li ZY, Zhu SS, Chen XJ, Zhu J, Chen Q, Zhang YQ, Zhang CL, Guo TT, Zhang LM. Biochem Biophys Res Commun. 2017 Nov 18;493(2):1018-1025. doi: 10.1016/j.bbrc.2017.09.099. Epub 2017 Sep 20. PubMed |
| Keratin 5/14mediated cell differentiation and transformation are regulated by TAp63 and Notch1 in oral squamous cell carcinomaderived cells. Srivastava SS, Alam H, Patil SJ, Shrinivasan R, Raikundalia S, Chaudhari PR, Vaidya MM. Oncol Rep. 2018 May;39(5):2393-2401. doi: 10.3892/or.2018.6298. Epub 2018 Mar 6. PubMed |
| The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution. Sobajima T, Yoshimura SI, Maeda T, Miyata H, Miyoshi E, Harada A. J Cell Biol. 2018 May 7;217(5):1777-1796. doi: 10.1083/jcb.201709123. Epub 2018 Mar 7. PubMed |
| Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition. Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D. Cancer Discov. 2018 Nov;8(11):1422-1437. doi: 10.1158/2159-8290.CD-18-0385. Epub 2018 Sep 4. PubMed |
| Translational and HIF-1alpha-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuede C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, Ohh M, Ferreira T, Greenwood C, Bridon G, Avizonis D, Ferbeyre G, Siegel P, Jones RG, Muller W, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I. Cell Metab. 2018 Dec 4;28(6):817-832.e8. doi: 10.1016/j.cmet.2018.09.001. Epub 2018 Sep 20. PubMed |
| Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, Liang H, Hung MC, You MJ, Sun Y, Ma L. Nat Genet. 2018 Dec;50(12):1705-1715. doi: 10.1038/s41588-018-0252-3. Epub 2018 Oct 22. PubMed |
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
Aries IM, Bodaar K, Karim SA, Chonghaile TN, Hinze L, Burns MA, Pfirrmann M, Degar J, Landrigan JT, Balbach S, Peirs S, Menten B, Isenhart R, Stevenson KE, Neuberg DS, Devidas M, Loh ML, Hunger SP, Teachey DT, Rabin KR, Winter SS, Dunsmore KP, Wood BL, Silverman LB, Sallan SE, Van Vlierberghe P, Orkin SH, Knoechel B, Letai AG, Gutierrez A.
J Exp Med. 2018 Nov 7. pii: jem.20180570. doi: 10.1084/jem.20180570.
PubMed
Associated Plasmids |
| A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, Delrow JJ, Overbaugh J, Emerman M. Elife. 2018 Dec 6;7. pii: 39823. doi: 10.7554/eLife.39823. PubMed |
| FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Zhang ZQ, Chen J, Huang WQ, Ning D, Liu QM, Wang C, Zhang L, Ren L, Chu L, Liang HF, Fan HN, Zhang BX, Chen XP. Mol Oncol. 2019 Apr;13(4):792-810. doi: 10.1002/1878-0261.12429. Epub 2019 Jan 24. PubMed |
| L1 drives IFN in senescent cells and promotes age-associated inflammation. De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beausejour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. PubMed |
| Essential role of glucokinase in the protection of pancreatic beta cells to the glucose energetic status. Marques P, Kamitz A, Bartolome A, Burillo J, Martinez H, Jimenez B, Fernandez-Rhodes M, Guillen C, Benito M. Cell Death Discov. 2019 Sep 30;5:138. doi: 10.1038/s41420-019-0219-x. eCollection 2019. PubMed |
| Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation. Matthew-Onabanjo AN, Janusis J, Mercado-Matos J, Carlisle AE, Kim D, Levine F, Cruz-Gordillo P, Richards R, Lee MJ, Shaw LM. Cancer Res. 2020 Jan 15;80(2):249-262. doi: 10.1158/0008-5472.CAN-19-1555. Epub 2019 Nov 19. PubMed |
| Global translation during early development depends on the essential transcription factor PRDM10. Han BY, Seah MKY, Brooks IR, Quek DHP, Huxley DR, Foo CS, Lee LT, Wollmann H, Guo H, Messerschmidt DM, Guccione E. Nat Commun. 2020 Jul 17;11(1):3603. doi: 10.1038/s41467-020-17304-3. PubMed |
| Identification of a long non-coding RNA regulator of liver carcinoma cell survival. Rybakova Y, Gonzalez JT, Bogorad R, Chauhan VP, Dong YL, Whittaker CA, Zatsepin T, Koteliansky V, Anderson DG. Cell Death Dis. 2021 Feb 15;12(2):178. doi: 10.1038/s41419-021-03453-w. PubMed |
| Role of Clathrin Light Chains in Regulating Invadopodia Formation. Mukenhirn M, Muraca F, Bucher D, Asberger E, Cappio Barazzone E, Cavalcanti-Adam EA, Boulant S. Cells. 2021 Feb 20;10(2). pii: cells10020451. doi: 10.3390/cells10020451. PubMed |
| Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Lopacinski AB, Sweatt AJ, Smolko CM, Gray-Gaillard E, Borgman CA, Shah M, Janes KA. Cell Syst. 2021 Apr 21;12(4):304-323.e13. doi: 10.1016/j.cels.2021.02.004. Epub 2021 Mar 18. PubMed |
| Gain-of-function p53(R172H) mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy. Siolas D, Vucic E, Kurz E, Hajdu C, Bar-Sagi D. Cell Rep. 2021 Aug 24;36(8):109578. doi: 10.1016/j.celrep.2021.109578. PubMed |
| The deubiquitinase OTUD1 inhibits non-small cell lung cancer progression by deubiquitinating and stabilizing KLF4. Ma X, Wang L, Shi G, Sun S. Thorac Cancer. 2022 Mar;13(5):761-770. doi: 10.1111/1759-7714.14320. Epub 2022 Jan 30. PubMed |
| CRB2 enhances malignancy of glioblastoma via activation of the NF-kappaB pathway. Wang Y, Bao G, Zhang M, Xiang J, Zhou H, Wahafu A, Wu W, Ma X, Huo L, Bai X, Xie W, Liu P, Wang M. Exp Cell Res. 2022 May 1;414(1):113077. doi: 10.1016/j.yexcr.2022.113077. Epub 2022 Feb 25. PubMed |
| Elevation of ADAM12 facilitates tumor progression by enhancing metastasis and immune infiltration in gastric cancer. Zhu H, Jiang W, Zhu H, Hu J, Tang B, Zhou Z, He X. Int J Oncol. 2022 May;60(5). pii: 51. doi: 10.3892/ijo.2022.5341. Epub 2022 Mar 22. PubMed |
| Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain. Pham AM, Ortiz LE, Lukacher AE, Kwun HJ. Cells. 2023 Jan 20;12(3):380. doi: 10.3390/cells12030380. PubMed |
| Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells. Pei J, Su Z, Zeng X, Zhong Y, Zhang Y, Yang Y, Lu Q, Li J, Deng Y. BMC Complement Med Ther. 2023 Apr 6;23(1):111. doi: 10.1186/s12906-023-03933-w. PubMed |
| The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate. Lackner A, Muller M, Gamperl M, Stoeva D, Langmann O, Papuchova H, Roitinger E, Durnberger G, Imre R, Mechtler K, Latos PA. Nat Commun. 2023 May 4;14(1):2559. doi: 10.1038/s41467-023-38101-8. PubMed |
| CLUH functions as a negative regulator of inflammation in human macrophages and determines ulcerative colitis pathogenesis. Khan S, Raj D, Sahu S, Naseer A, Singh NC, Kumari S, Ishteyaque S, Sharma J, Lakra P, Mugale MN, Trivedi AK, Srivastava M, Chandra T, Bhosale V, Barthwal MK, Gupta SK, Mitra K, Nazir A, Ghoshal UC, Lahiri A. JCI Insight. 2023 Jun 8;8(11):e161096. doi: 10.1172/jci.insight.161096. PubMed |
| LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling. Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M. Mol Carcinog. 2023 Jul 14. doi: 10.1002/mc.23606. PubMed |
| Promyelocytic leukemia protein regulates angiogenesis and epithelial-mesenchymal transition to limit metastasis in MDA-MB-231 breast cancer cells. Vogiatzoglou AP, Spanou S, Sachini N, Drakos E, Nikolaou C, Makatounakis T, Kretsovali A, Papamatheakis J. Mol Oncol. 2023 Oct;17(10):2090-2108. doi: 10.1002/1878-0261.13501. Epub 2023 Sep 4. PubMed |
| Matrix confinement modulates 3D spheroid sorting and burst-like collective migration. Cai G, Li X, Lin SS, Chen SJ, Rodgers NC, Koning KM, Bi D, Liu AP. bioRxiv [Preprint]. 2024 Feb 4:2023.07.23.549940. doi: 10.1101/2023.07.23.549940. PubMed |
| Spatiotemporal, optogenetic control of gene expression in organoids. Legnini I, Emmenegger L, Zappulo A, Rybak-Wolf A, Wurmus R, Martinez AO, Jara CC, Boltengagen A, Hessler T, Mastrobuoni G, Kempa S, Zinzen R, Woehler A, Rajewsky N. Nat Methods. 2023 Oct;20(10):1544-1552. doi: 10.1038/s41592-023-01986-w. Epub 2023 Sep 21. PubMed |
| Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer. Xia L, Nie T, Lu F, Huang L, Shi X, Ren D, Lu J, Li X, Xu T, Cui B, Wang Q, Gao G, Yang Q. Autophagy. 2024 Mar;20(3):505-524. doi: 10.1080/15548627.2023.2259735. Epub 2023 Sep 29. PubMed |
| Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis. Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X. Int J Cancer. 2024 Feb 15;154(4):723-737. doi: 10.1002/ijc.34769. Epub 2023 Oct 19. PubMed |
| USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma. Chen J, Ning D, Du P, Liu Q, Mo J, Liang H, Zhang W, Zhang M, Jiang L, Zhang B, Chen X. Oncogene. 2024 Jan;43(2):123-135. doi: 10.1038/s41388-023-02847-8. Epub 2023 Nov 16. PubMed |
| The actin-bundling protein, PLS3, is part of the mechanoresponsive machinery that regulates osteoblast mineralization. Chin SM, Unnold-Cofre C, Naismith T, Jansen S. Front Cell Dev Biol. 2023 Nov 27;11:1141738. doi: 10.3389/fcell.2023.1141738. eCollection 2023. PubMed |
| Akt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis. Lee DM, Kim IY, Lee HJ, Seo MJ, Cho MY, Lee HI, Yoon G, Ji JH, Park SS, Jeong SY, Choi EK, Choi YH, Yun CO, Yeo M, Kim E, Choi KS. Cell Death Dis. 2024 Jan 13;15(1):48. doi: 10.1038/s41419-024-06434-x. PubMed |
| The role of Smarcad1 in retroviral repression in mouse embryonic stem cells. Bren I, Tal A, Strauss C, Schlesinger S. Mob DNA. 2024 Mar 11;15(1):4. doi: 10.1186/s13100-024-00314-z. PubMed |
| mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjornsson M, Marciano R, Scharov K, Planque M, Vriens K, Christen S, Funk CM, Hassiepen C, Kahler A, Heider B, Picard D, Lim JKM, Stefanski A, Bendrin K, Vargas-Toscano A, Kahlert UD, Stuhler K, Remke M, Elkabets M, Grunewald TGP, Reichert AS, Fendt SM, Schulze A, Reifenberger G, Rotblat B, Leprivier G. Nat Commun. 2024 May 14;15(1):4083. doi: 10.1038/s41467-024-48386-y. PubMed |
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