MYD88 flag Citations (13)
Originally described in: MYD88Unpublished
Articles Citing MYD88 flag
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| TBK1-associated protein in endolysosomes (TAPE) is an innate immune regulator modulating the TLR3 and TLR4 signaling pathways. Chang CH, Lai LC, Cheng HC, Chen KR, Syue YZ, Lu HC, Lin WY, Chen SH, Huang HS, Shiau AL, Lei HY, Qin J, Ling P. J Biol Chem. 2011 Mar 4;286(9):7043-51. doi: 10.1074/jbc.M110.164632. Epub 2010 Dec 28. PubMed |
| Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin B by a synthetic dimeric BB-loop mimetic of MyD88. Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J Jr, Saikh KU. PLoS One. 2012;7(7):e40773. doi: 10.1371/journal.pone.0040773. Epub 2012 Jul 27. PubMed |
| Phosphatidylinositol 4-phosphate 5-kinase alpha facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) location. Nguyen TT, Kim YM, Kim TD, Le OT, Kim JJ, Kang HC, Hasegawa H, Kanaho Y, Jou I, Lee SY. J Biol Chem. 2013 Feb 22;288(8):5645-59. doi: 10.1074/jbc.M112.410126. Epub 2013 Jan 7. PubMed |
| Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis. Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber AN, Aepfelbacher M, Ruckdeschel K. J Immunol. 2014 Feb 1;192(3):1209-19. doi: 10.4049/jimmunol.1203464. Epub 2013 Dec 20. PubMed |
| Structure-Based Design and Synthesis of a Small Molecule that Exhibits Anti-inflammatory Activity by Inhibition of MyD88-mediated Signaling to Bacterial Toxin Exposure. Alam S, Javor S, Degardin M, Ajami D, Rebek M, Kissner TL, Waag DM, Rebek J Jr, Saikh KU. Chem Biol Drug Des. 2015 Aug;86(2):200-9. doi: 10.1111/cbdd.12477. Epub 2014 Dec 8. PubMed |
| Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen. Olson MA, Lee MS, Kissner TL, Alam S, Waugh DS, Saikh KU. Sci Rep. 2015 Sep 18;5:14246. doi: 10.1038/srep14246. PubMed |
| alpha-Lipoic Acids Promote the Protein Synthesis of C2C12 Myotubes by the TLR2/PI3K Signaling Pathway. Jing Y, Cai X, Xu Y, Zhu C, Wang L, Wang S, Zhu X, Gao P, Zhang Y, Jiang Q, Shu G. J Agric Food Chem. 2016 Mar 2;64(8):1720-9. doi: 10.1021/acs.jafc.5b05952. Epub 2016 Feb 22. PubMed |
| Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1alpha-Mediated Inflammatory Disease. Gurung P, Fan G, Lukens JR, Vogel P, Tonks NK, Kanneganti TD. Immunity. 2017 Apr 18;46(4):635-648. doi: 10.1016/j.immuni.2017.03.014. Epub 2017 Apr 11. PubMed |
| MyD88 promotes myoblast fusion in a cell-autonomous manner. Hindi SM, Shin J, Gallot YS, Straughn AR, Simionescu-Bankston A, Hindi L, Xiong G, Friedland RP, Kumar A. Nat Commun. 2017 Nov 20;8(1):1624. doi: 10.1038/s41467-017-01866-w. PubMed |
| Small Molecule Analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling. Suckling CJ, Alam S, Olson MA, Saikh KU, Harnett MM, Harnett W. Sci Rep. 2018 Feb 1;8(1):2123. doi: 10.1038/s41598-018-20388-z. PubMed |
| Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts. Chen J, Ullah H, Zheng Z, Gu X, Su C, Xiao L, Wu X, Xiong F, Li Q, Zha L. BMC Complement Med Ther. 2020 Jun 3;20(1):167. doi: 10.1186/s12906-020-2864-2. PubMed |
| A small molecule inhibitor of MyD88 exhibits broad spectrum antiviral activity by up regulation of type I interferon. Saikh KU, Morazzani EM, Piper AE, Bakken RR, Glass PJ. Antiviral Res. 2020 Sep;181:104854. doi: 10.1016/j.antiviral.2020.104854. Epub 2020 Jul 2. PubMed |
| Inflammation Induced by Lipopolysaccharide and Palmitic Acid Increases Cholesterol Accumulation via Enhancing Myeloid Differentiation Factor 88 Expression in HepG2 Cells. Chen J, Liu Y, Luo H, Chen G, Zheng Z, Wang T, Hu X, Zhao Y, Tang J, Su C, Zha L. Pharmaceuticals (Basel). 2022 Jun 30;15(7):813. doi: 10.3390/ph15070813. PubMed |
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