Skip to main content
Addgene

pcDNA3-EGFP-Rac1-Q61L Citations (29)

Originally described in: Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas.
Subauste MC, Von Herrath M, Benard V, Chamberlain CE, Chuang TH, Chu K, Bokoch GM, Hahn KM J Biol Chem. 2000 Mar 31. 275(13):9725-33.
PubMed Journal

Articles Citing pcDNA3-EGFP-Rac1-Q61L

Articles
Targeting the PI3K p110alpha isoform inhibits medulloblastoma proliferation, chemoresistance, and migration. Guerreiro AS, Fattet S, Fischer B, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A. Clin Cancer Res. 2008 Nov 1;14(21):6761-9. doi: 10.1158/1078-0432.CCR-08-0385. PubMed
The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Doherty GJ, Ahlund MK, Howes MT, Moren B, Parton RG, McMahon HT, Lundmark R. Mol Biol Cell. 2011 Nov;22(22):4380-9. doi: 10.1091/mbc.E10-12-0936. Epub 2011 Sep 30. PubMed
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms. Ninkovic J, Roy S. Am J Pathol. 2012 Mar;180(3):1068-79. doi: 10.1016/j.ajpath.2011.11.034. Epub 2012 Jan 14. PubMed
Hyperstimulation of macropinocytosis leads to lysosomal dysfunction during exposure to methamphetamine in SH-SY5Y cells. Nara A, Aki T, Funakoshi T, Unuma K, Uemura K. Brain Res. 2012 Jul 23;1466:1-14. doi: 10.1016/j.brainres.2012.05.017. Epub 2012 May 14. PubMed
Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1alpha with CREB-binding protein. Gautier-Stein A, Soty M, Chilloux J, Zitoun C, Rajas F, Mithieux G. Diabetes. 2012 Oct;61(10):2451-60. Epub 2012 Jul 10. PubMed
Low-Rac1 activity downregulates MC3T3-E1 osteoblastic cell motility on a nanoscale topography prepared on polystyrene substrates in vitro. Zheng L, Kim HM. J Biomed Mater Res A. 2013 Jun;101(6):1629-36. doi: 10.1002/jbm.a.34463. Epub 2012 Nov 27. PubMed
Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes. Dehapiot B, Carriere V, Carroll J, Halet G. Dev Biol. 2013 May 1;377(1):202-12. doi: 10.1016/j.ydbio.2013.01.029. Epub 2013 Feb 4. PubMed
Ran GTPase promotes oocyte polarization by regulating ERM (Ezrin/Radixin/Moesin) inactivation. Dehapiot B, Halet G. Cell Cycle. 2013 Jun 1;12(11):1672-8. doi: 10.4161/cc.24901. Epub 2013 May 8. PubMed
ROCK inhibition activates MCF-7 cells. Yang S, Kim HM. PLoS One. 2014 Feb 11;9(2):e88489. doi: 10.1371/journal.pone.0088489. eCollection 2014. PubMed
The PDZ-binding domain of syndecan-2 inhibits LFA-1 high-affinity conformation. Rovira-Clave X, Angulo-Ibanez M, Reina M, Espel E. Cell Signal. 2014 Jul;26(7):1489-99. doi: 10.1016/j.cellsig.2014.03.012. Epub 2014 Mar 21. PubMed

Associated Plasmids

ARHGAP22 localizes at endosomes and regulates actin cytoskeleton. Mori M, Saito K, Ohta Y. PLoS One. 2014 Jun 16;9(6):e100271. doi: 10.1371/journal.pone.0100271. eCollection 2014. PubMed
Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells. Zhou HC, Fang JH, Luo X, Zhang L, Yang J, Zhang C, Zhuang SM. Oncotarget. 2014 Dec 15;5(23):12177-88. PubMed
FilGAP, a Rho-ROCK-regulated GAP for Rac, controls adherens junctions in MDCK cells. Nakahara S, Tsutsumi K, Zuinen T, Ohta Y. J Cell Sci. 2015 Jun 1;128(11):2047-56. doi: 10.1242/jcs.160192. Epub 2015 Apr 23. PubMed
Dosage-dependent Role of RAC1 in Podocyte Injury. Wan X, Lee MS, Zhou W. Am J Physiol Renal Physiol. 2016 Jan 20:ajprenal.00381.2015. doi: 10.1152/ajprenal.00381.2015. PubMed
Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Lee NK, Fok KW, White A, Wilson NH, O'Leary CJ, Cox HL, Michael M, Yap AS, Cooper HM. Nat Commun. 2016 Mar 31;7:11082. doi: 10.1038/ncomms11082. PubMed
Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. Li L, Chen J, Xiong G, St Clair DK, Xu W, Xu R. J Cell Sci. 2017 Jan 1;130(1):190-202. doi: 10.1242/jcs.186031. Epub 2016 Sep 21. PubMed
Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid DNA Delivery by Electrotransfection. Mao M, Wang L, Chang CC, Rothenberg KE, Huang J, Wang Y, Hoffman BD, Liton PB, Yuan F. Mol Ther. 2017 Mar 1;25(3):803-815. doi: 10.1016/j.ymthe.2016.12.009. Epub 2017 Jan 24. PubMed
The P2X7 receptor is an upstream regulator of dynamic blebbing and a pluripotency marker in human embryonic stem cells. Weng NJ, Talbot P. Stem Cell Res. 2017 Aug;23:39-49. doi: 10.1016/j.scr.2017.06.007. Epub 2017 Jun 16. PubMed
A Cytokine-like Protein DKK3 Is Atheroprotective. Yu B, Kiechl S, Qi D, Wang X, Song Y, Weger S, Mayr A, Le Bras A, Karamariti E, Zhang Z, Del Barco Barrantes I, Niehrs C, Schett G, Hu Y, Wang W, Willeit J, Qu A, Xu Q. Circulation. 2017 Jul 3. pii: CIRCULATIONAHA.117.027690. doi: 10.1161/CIRCULATIONAHA.117.027690. PubMed
The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex. Khan MH, Salomaa SI, Jacquemet G, Butt U, Miihkinen M, Deguchi T, Kremneva E, Lappalainen P, Humphries MJ, Pouwels J. J Cell Sci. 2017 Sep 15;130(18):3094-3107. doi: 10.1242/jcs.200329. Epub 2017 Aug 3. PubMed
Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis. Niit M, Arulanandam R, Cass J, Geletu M, Hoskin V, Cote G, Gunning P, Elliott B, Raptis L. Exp Cell Res. 2017 Dec 1;361(1):112-125. doi: 10.1016/j.yexcr.2017.10.008. Epub 2017 Oct 13. PubMed
Novel role of Gialpha2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells. Caggia S, Chunduri H, Millena AC, Perkins JN, Venugopal SV, Vo BT, Li C, Tu Y, Khan SA. J Cell Physiol. 2018 Jan;234(1):802-815. doi: 10.1002/jcp.26894. Epub 2018 Aug 4. PubMed
Type VI collagen promotes lung epithelial cell spreading and wound-closure. Mereness JA, Bhattacharya S, Wang Q, Ren Y, Pryhuber GS, Mariani TJ. PLoS One. 2018 Dec 14;13(12):e0209095. doi: 10.1371/journal.pone.0209095. eCollection 2018. PubMed
C3a and suPAR drive versican V1 expression in tubular cells of focal segmental glomerulosclerosis. Han R, Hu S, Qin W, Shi J, Hou Q, Wang X, Xu X, Zhang M, Zeng C, Liu Z, Bao H. JCI Insight. 2019 Apr 4;4(7). pii: 122912. doi: 10.1172/jci.insight.122912. eCollection 2019 Apr 4. PubMed
Exogenous 8-hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1-NADPH oxidase signaling. Shin SK, Kim KO, Kim SH, Kwon OS, Choi CS, Jeong SH, Kim YS, Kim JH, Chung MH. J Gastroenterol Hepatol. 2020 Jun;35(6):1078-1087. doi: 10.1111/jgh.14979. Epub 2020 Jan 23. PubMed
Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells. Venugopal SV, Caggia S, Gambrell-Sanders D, Khan SA. Prostate. 2020 Apr;80(5):412-423. doi: 10.1002/pros.23956. Epub 2020 Jan 29. PubMed
Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration. Zong H, Hazelbaker M, Moe C, Ems-McClung SC, Hu K, Walczak CE. Mol Biol Cell. 2021 Apr 1;32(7):590-604. doi: 10.1091/mbc.E20-05-0301. Epub 2021 Feb 10. PubMed
Nuclear RAC1 is a modulator of the doxorubicin-induced DNA damage response. Kitzinger R, Fritz G, Henninger C. Biochim Biophys Acta Mol Cell Res. 2022 Oct;1869(10):119320. doi: 10.1016/j.bbamcr.2022.119320. Epub 2022 Jul 8. PubMed
An Inducible T7 Polymerase System for High-Level Protein Expression in Diverse Gram-Negative Bacteria. Greenwich JL, Alakavuklar MA, Fuqua C. Microbiol Resour Announc. 2023 Feb 16;12(2):e0111922. doi: 10.1128/mra.01119-22. Epub 2023 Jan 16. PubMed

Associated Plasmids

If you have published an article using this material, please email us at [email protected] to have your article added to this page.