pcDNA3-EGFP-RhoA-Q63L Citations (38)
Originally described in: Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas.Subauste MC, Von Herrath M, Benard V, Chamberlain CE, Chuang TH, Chu K, Bokoch GM, Hahn KM J Biol Chem. 2000 Mar 31. 275(13):9725-33. PubMed Journal
Articles Citing pcDNA3-EGFP-RhoA-Q63L
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| Elevated cholesterol levels in the plasma membranes of macrophages inhibit migration by disrupting RhoA regulation. Nagao T, Qin C, Grosheva I, Maxfield FR, Pierini LM. Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1596-602. Epub 2007 May 10. PubMed |
Engineering Ca(2+)/calmodulin-mediated modulation of protein translocation by overlapping binding and signaling peptide sequences.
Mills E, Truong K.
Cell Calcium. 2010 Feb 16. ():.
PubMed
Associated Plasmids |
Structure based design of a Ca2+-sensitive RhoA protein that controls cell morphology.
Mills E, Pham E, Truong K.
Cell Calcium. 2010 Oct;48(4):195-201.
PubMed
Associated Plasmids |
| Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42. Navarro A, Perez RE, Rezaiekhaligh MH, Mabry SM, Ekekezie II. Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42. doi: 10.1152/ajplung.00171.2010. Epub 2010 Oct 29. PubMed |
| Mechanisms by which the inhibition of specific intracellular signaling pathways increase osteoblast proliferation on apatite surfaces. Yang S, Tian YS, Lee YJ, Yu FH, Kim HM. Biomaterials. 2011 Apr;32(11):2851-61. doi: 10.1016/j.biomaterials.2011.01.015. Epub 2011 Feb 1. PubMed |
| WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization. Kim JH, Mukherjee A, Madhavan SM, Konieczkowski M, Sedor JR. Am J Physiol Renal Physiol. 2012 Jan 1;302(1):F103-15. doi: 10.1152/ajprenal.00419.2011. Epub 2011 Sep 7. PubMed |
| The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Doherty GJ, Ahlund MK, Howes MT, Moren B, Parton RG, McMahon HT, Lundmark R. Mol Biol Cell. 2011 Nov;22(22):4380-9. doi: 10.1091/mbc.E10-12-0936. Epub 2011 Sep 30. PubMed |
Ca2+-mediated synthetic biosystems offer protein design versatility, signal specificity, and pathway rewiring.
Mills E, Truong K.
Chem Biol. 2011 Dec 23;18(12):1611-9.
PubMed
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| The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior. Yang S, Kim HM. Biomaterials. 2012 Apr;33(10):2902-15. doi: 10.1016/j.biomaterials.2011.12.051. Epub 2012 Jan 13. PubMed |
| Simultaneous assembly of two target proteins using split inteins for live cell imaging. Wong S, Mills E, Truong K. Protein Eng Des Sel. 2013 Mar;26(3):207-13. doi: 10.1093/protein/gzs100. Epub 2012 Dec 4. PubMed |
Matrix identity and tractional forces influence indirect cardiac reprogramming.
Kong YP, Carrion B, Singh RK, Putnam AJ.
Sci Rep. 2013 Dec 11;3:3474. doi: 10.1038/srep03474.
PubMed
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| Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas. Palomero T, Couronne L, Khiabanian H, Kim MY, Ambesi-Impiombato A, Perez-Garcia A, Carpenter Z, Abate F, Allegretta M, Haydu JE, Jiang X, Lossos IS, Nicolas C, Balbin M, Bastard C, Bhagat G, Piris MA, Campo E, Bernard OA, Rabadan R, Ferrando AA. Nat Genet. 2014 Feb;46(2):166-70. doi: 10.1038/ng.2873. Epub 2014 Jan 12. PubMed |
| ROCK inhibition activates MCF-7 cells. Yang S, Kim HM. PLoS One. 2014 Feb 11;9(2):e88489. doi: 10.1371/journal.pone.0088489. eCollection 2014. PubMed |
The PDZ-binding domain of syndecan-2 inhibits LFA-1 high-affinity conformation.
Rovira-Clave X, Angulo-Ibanez M, Reina M, Espel E.
Cell Signal. 2014 Jul;26(7):1489-99. doi: 10.1016/j.cellsig.2014.03.012. Epub 2014 Mar 21.
PubMed
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| Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells. Wong A, Loots GG, Yellowley CE, Dose AC, Genetos DC. Bone. 2015 Jul 4;81:97-103. doi: 10.1016/j.bone.2015.07.002. PubMed |
| An Engineered Split Intein for Photoactivated Protein Trans-Splicing. Wong S, Mosabbir AA, Truong K. PLoS One. 2015 Aug 28;10(8):e0135965. doi: 10.1371/journal.pone.0135965. eCollection 2015. PubMed |
| Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization. Lomakin AJ, Lee KC, Han SJ, Bui DA, Davidson M, Mogilner A, Danuser G. Nat Cell Biol. 2015 Nov;17(11):1435-45. doi: 10.1038/ncb3246. Epub 2015 Sep 28. PubMed |
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.
Yu CH, Rafiq NB, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang YH, Kawauchi K, Jones GE, Sheetz MP.
Nat Commun. 2015 Oct 28;6:8672. doi: 10.1038/ncomms9672.
PubMed
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| Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway. Yeh CW, Hsu LS. Mol Neurobiol. 2015 Dec 3. PubMed |
| Neuronal Filopodium Formation Induced by the Membrane Glycoprotein M6a (Gpm6a) is Facilitated by Coronin-1a, Rac1 and p21-Activated Kinase 1 (Pak1). Alvarez Julia A, Frasch AC, Fuchsova B. J Neurochem. 2016 Jan 26. doi: 10.1111/jnc.13552. PubMed |
| Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Yuan X, Cao J, He X, Serra R, Qu J, Cao X, Yang S. Nat Commun. 2016 Mar 21;7:11024. doi: 10.1038/ncomms11024. PubMed |
| TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-beta1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling. Xiong F, Li X, Yang Z, Wang Y, Gong W, Huang J, Chen C, Liu P, Huang H. Endocrine. 2016 Dec;54(3):657-670. Epub 2016 Jul 28. PubMed |
| YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed |
| A Cytokine-like Protein DKK3 Is Atheroprotective. Yu B, Kiechl S, Qi D, Wang X, Song Y, Weger S, Mayr A, Le Bras A, Karamariti E, Zhang Z, Del Barco Barrantes I, Niehrs C, Schett G, Hu Y, Wang W, Willeit J, Qu A, Xu Q. Circulation. 2017 Jul 3. pii: CIRCULATIONAHA.117.027690. doi: 10.1161/CIRCULATIONAHA.117.027690. PubMed |
| Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism. Singh RK, Haka AS, Brumfield A, Grosheva I, Bhardwaj P, Chin HF, Xiong Y, Hla T, Maxfield FR. J Lipid Res. 2017 Oct;58(10):1977-1987. doi: 10.1194/jlr.M076398. Epub 2017 Aug 16. PubMed |
| The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics. O'Loughlin T, Masters TA, Buss F. EMBO Rep. 2018 Apr;19(4). pii: embr.201744884. doi: 10.15252/embr.201744884. Epub 2018 Feb 21. PubMed |
| PKCepsilon Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Schaffer TB, Smith JE, Cook EK, Phan T, Margolis SS. Cell Rep. 2018 Nov 27;25(9):2470-2483.e8. doi: 10.1016/j.celrep.2018.11.005. PubMed |
| GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, Del Rio Hernandez AE. EMBO Rep. 2019 Jan;20(1). pii: embr.201846556. doi: 10.15252/embr.201846556. Epub 2018 Dec 11. PubMed |
Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics
Budnar S, Husain KB, Gomez GA, Naghibosadat M, Varma A, Verma S, Hamilton NA, Morris RG, Yap AS.
Dev Cell. 2019 Jun 17;49(6):894-906.e12. doi: 10.1016/j.devcel.2019.04.031. Epub 2019 May 16.
PubMed
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| Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells. Townshend RF, Shao Y, Wang S, Cortez CL, Esfahani SN, Spence JR, O'Shea KS, Fu J, Gumucio DL, Taniguchi K. Front Cell Dev Biol. 2020 Oct 15;8:588941. doi: 10.3389/fcell.2020.588941. eCollection 2020. PubMed |
| Tension heterogeneity directs form and fate to pattern the myocardial wall. Priya R, Allanki S, Gentile A, Mansingh S, Uribe V, Maischein HM, Stainier DYR. Nature. 2020 Dec;588(7836):130-134. doi: 10.1038/s41586-020-2946-9. Epub 2020 Nov 18. PubMed |
| Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. McCray BA, Diehl E, Sullivan JM, Aisenberg WH, Zaccor NW, Lau AR, Rich DJ, Goretzki B, Hellmich UA, Lloyd TE, Sumner CJ. Nat Commun. 2021 Mar 4;12(1):1444. doi: 10.1038/s41467-021-21699-y. PubMed |
| Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells. Wu D, Harrison DL, Szasz T, Yeh CF, Shentu TP, Meliton A, Huang RT, Zhou Z, Mutlu GM, Huang J, Fang Y. Nat Metab. 2021 May;3(5):714-727. doi: 10.1038/s42255-021-00390-y. Epub 2021 May 24. PubMed |
| Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA. Sala S, Oakes PW. Mol Biol Cell. 2021 Aug 19;32(18):1758-1771. doi: 10.1091/mbc.E21-03-0156. Epub 2021 May 26. PubMed |
| EphA2 signaling within integrin adhesions regulates fibrillar adhesion elongation and fibronectin deposition. Finney AC, Scott ML, Reeves KA, Wang D, Alfaidi M, Schwartz JC, Chitmon CM, Acosta CH, Murphy JM, Alexander JS, Pattillo CB, Lim ST, Orr AW. Matrix Biol. 2021 Sep;103-104:1-21. doi: 10.1016/j.matbio.2021.09.001. Epub 2021 Sep 17. PubMed |
| A cell-based GEF assay reveals new substrates for DENN domains and a role for DENND2B in primary ciliogenesis. Kumar R, Francis V, Kulasekaran G, Khan M, Armstrong GAB, McPherson PS. Sci Adv. 2022 Feb 25;8(8):eabk3088. doi: 10.1126/sciadv.abk3088. Epub 2022 Feb 23. PubMed |
| p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation. Zanin JP, Friedman WJ. Elife. 2022 Aug 30;11:e79934. doi: 10.7554/eLife.79934. PubMed |
| Nuclear softening mediated by Sun2 suppression delays mechanical stress-induced cellular senescence. Yue X, Cui J, Sun Z, Liu L, Li Y, Shao L, Feng Q, Wang Z, Hambright WS, Cui Y, Huard J, Mu Y, Mu X. Cell Death Discov. 2023 May 17;9(1):167. doi: 10.1038/s41420-023-01467-1. PubMed |
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