pC13N-dCas9-BFP-KRAB Citations (8)

Originally described in: CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.
Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M Neuron. 2019 Aug 5. pii: S0896-6273(19)30640-3. doi: 10.1016/j.neuron.2019.07.014. PubMed Journal

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Articles Citing pC13N-dCas9-BFP-KRAB

Articles
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes. Kanfer G, Sarraf SA, Maman Y, Baldwin H, Dominguez-Martin E, Johnson KR, Ward ME, Kampmann M, Lippincott-Schwartz J, Youle RJ. J Cell Biol. 2021 Feb 1;220(2). pii: 211694. doi: 10.1083/jcb.202006180. PubMed
Bioengineered optogenetic model of human neuromuscular junction. Vila OF, Chavez M, Ma SP, Yeager K, Zholudeva LV, Colon-Mercado JM, Qu Y, Nash TR, Lai C, Feliciano CM, Carter M, Kamm RD, Judge LM, Conklin BR, Ward ME, McDevitt TC, Vunjak-Novakovic G. Biomaterials. 2021 Sep;276:121033. doi: 10.1016/j.biomaterials.2021.121033. Epub 2021 Jul 30. PubMed
CRISPR-Based Screening for Stress Response Factors in Mammalian Cells. Guo X, Kampmann M. Methods Mol Biol. 2022;2428:19-40. doi: 10.1007/978-1-0716-1975-9_2. PubMed
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression. Xiao W, Wang J, Wang X, Cai S, Guo Y, Ye L, Li D, Hu A, Jin S, Yuan B, Zhou Y, Li Q, Tong Q, Zheng L. Autophagy. 2022 Mar 6:1-21. doi: 10.1080/15548627.2022.2044651. PubMed
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states. Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M. Nat Neurosci. 2022 Nov;25(11):1528-1542. doi: 10.1038/s41593-022-01180-9. Epub 2022 Oct 27. PubMed Associated Plasmids pKL123
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Parra Bravo C, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D, Kanaan NM, Gan L, Condello C, Swaney DL, Kampmann M. bioRxiv. 2023 Jun 26:2023.06.16.545386. doi: 10.1101/2023.06.16.545386. Preprint. PubMed
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Cell. 2024 May 9;187(10):2446-2464.e22. doi: 10.1016/j.cell.2024.03.015. Epub 2024 Apr 5. PubMed
Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease. Ferguson R, Goold R, Coupland L, Flower M, Tabrizi SJ. Am J Hum Genet. 2024 Jun 6;111(6):1165-1183. doi: 10.1016/j.ajhg.2024.04.015. Epub 2024 May 14. PubMed

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