pLVTHM Citations (174)
Originally described in: Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference.Wiznerowicz M, Trono D J Virol. 2003 Aug . 77(16):8957-61. PubMed Journal
Articles Citing pLVTHM
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ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential. Carcamo-Orive I, Tejados N, Delgado J, Gaztelumendi A, Otaegui D, Lang V, Trigueros C. Exp Cell Res. 2008 May 1;314(8):1777-88. doi: 10.1016/j.yexcr.2008.01.020. Epub 2008 Feb 6. PubMed |
A polypyrimidine tract-binding protein-dependent pathway of mRNA stability initiates with CpG activation of primary B cells. Porter JF, Vavassori S, Covey LR. J Immunol. 2008 Sep 1;181(5):3336-45. PubMed |
Requirement of IFN-gamma-mediated indoleamine 2,3-dioxygenase expression in the modulation of lymphocyte proliferation by human adipose-derived stem cells. DelaRosa O, Lombardo E, Beraza A, Mancheno-Corvo P, Ramirez C, Menta R, Rico L, Camarillo E, Garcia L, Abad JL, Trigueros C, Delgado M, Buscher D. Tissue Eng Part A. 2009 Oct;15(10):2795-806. doi: 10.1089/ten.TEA.2008.0630. PubMed |
Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines. Du ZW, Hu BY, Ayala M, Sauer B, Zhang SC. Stem Cells. 2009 May . 27(5):1032-41. PubMed |
Multipurpose modular lentiviral vectors for RNA interference and transgene expression. Kesireddy V, van der Ven PF, Furst DO. Mol Biol Rep. 2010 Jul;37(6):2863-70. doi: 10.1007/s11033-009-9840-8. Epub 2009 Oct 2. PubMed |
Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor. Lu L, Wang S, Zheng L, Li X, Suswam EA, Zhang X, Wheeler CG, Nabors LB, Filippova N, King PH. J Biol Chem. 2009 Dec 4. 284(49):33989-98. PubMed |
Pharmacological and genetic accumulation of hypoxia-inducible factor-1alpha enhances excitatory synaptic transmission in hippocampal neurons through the production of vascular endothelial growth factor. Huang YF, Yang CH, Huang CC, Tai MH, Hsu KS. J Neurosci. 2010 Apr 28;30(17):6080-93. doi: 10.1523/JNEUROSCI.5493-09.2010. PubMed |
Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk. Carcamo-Orive I, Gaztelumendi A, Delgado J, Tejados N, Dorronsoro A, Fernandez-Rueda J, Pennington DJ, Trigueros C. J Bone Miner Res. 2010 Oct;25(10):2115-25. doi: 10.1002/jbmr.120. PubMed |
PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons. Ning K, Drepper C, Valori CF, Ahsan M, Wyles M, Higginbottom A, Herrmann T, Shaw P, Azzouz M, Sendtner M. Hum Mol Genet. 2010 Aug 15;19(16):3159-68. doi: 10.1093/hmg/ddq226. Epub 2010 Jun 4. PubMed |
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Jun JI, Lau LF. Nat Cell Biol. 2010 Jul;12(7):676-85. doi: 10.1038/ncb2070. Epub 2010 Jun 6. PubMed |
Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M. Brain. 2011 Feb;134(Pt 2):506-17. doi: 10.1093/brain/awq345. Epub 2011 Jan 12. PubMed |
Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells. Matus-Nicodemos R, Vavassori S, Castro-Faix M, Valentin-Acevedo A, Singh K, Marcelli V, Covey LR. J Immunol. 2011 Feb 15;186(4):2164-71. doi: 10.4049/jimmunol.1003236. Epub 2011 Jan 17. PubMed |
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC. Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879. Epub 2011 Feb 23. PubMed |
Somatic coding mutations in human induced pluripotent stem cells. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. PubMed |
The RNA-binding protein HuR promotes glioma growth and treatment resistance. Filippova N, Yang X, Wang Y, Gillespie GY, Langford C, King PH, Wheeler C, Nabors LB. Mol Cancer Res. 2011 May;9(5):648-59. doi: 10.1158/1541-7786.MCR-10-0325. Epub 2011 Apr 15. PubMed |
Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed |
Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways. Lee CC, Huang CC, Hsu KS. Neuropharmacology. 2011 Sep;61(4):867-79. doi: 10.1016/j.neuropharm.2011.06.003. Epub 2011 Jun 12. PubMed |
The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. Kim JY, Oh MH, Bernard LP, Macara IG, Zhang H. J Biol Chem. 2011 Oct 28;286(43):37615-24. doi: 10.1074/jbc.M111.268029. Epub 2011 Sep 7. PubMed |
The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis. Pelletier J, Dayan F, Durivault J, Ilc K, Pecou E, Pouyssegur J, Mazure NM. Oncogene. 2012 Jun 14;31(24):2989-3001. doi: 10.1038/onc.2011.471. Epub 2011 Oct 17. PubMed |
FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed |
Angiogenic properties of myofibroblasts isolated from normal human skin wounds. Mayrand D, Laforce-Lavoie A, Larochelle S, Langlois A, Genest H, Roy M, Moulin VJ. Angiogenesis. 2012 Jun;15(2):199-212. doi: 10.1007/s10456-012-9253-5. Epub 2012 Feb 18. PubMed |
Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase. Perez-Leal O, Barrero CA, Clarkson AB, Casero RA Jr, Merali S. Mol Cell Biol. 2012 Apr;32(8):1453-67. doi: 10.1128/MCB.06444-11. Epub 2012 Feb 21. PubMed |
Histone deacetylase 3 modulates the expansion of human hematopoietic stem cells. Elizalde C, Fernandez-Rueda J, Salcedo JM, Dorronsoro A, Ferrin I, Jakobsson E, Trigueros C. Stem Cells Dev. 2012 Sep 20;21(14):2581-91. doi: 10.1089/scd.2011.0698. Epub 2012 May 8. PubMed |
IL1beta induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-kappaB. Carrero R, Cerrada I, Lledo E, Dopazo J, Garcia-Garcia F, Rubio MP, Trigueros C, Dorronsoro A, Ruiz-Sauri A, Montero JA, Sepulveda P. Stem Cell Rev. 2012 Sep;8(3):905-16. doi: 10.1007/s12015-012-9364-9. PubMed |
Zfp296 is a novel, pluripotent-specific reprogramming factor. Fischedick G, Klein DC, Wu G, Esch D, Hoing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Scholer HR, Sterneckert JL. PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2. PubMed |
LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump. Fan S, Niu Y, Tan N, Wu Z, Wang Y, You H, Ke R, Song J, Shen Q, Wang W, Yao G, Shu H, Lin H, Yao M, Zhang Z, Gu J, Qin W. Oncogene. 2013 Mar 28;32(13):1682-90. doi: 10.1038/onc.2012.183. Epub 2012 May 14. PubMed |
Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells. Galperin E, Abdelmoti L, Sorkin A. PLoS One. 2012;7(5):e36469. doi: 10.1371/journal.pone.0036469. Epub 2012 May 14. PubMed |
A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology. Ustek D, Sirma S, Gumus E, Arikan M, Cakiris A, Abaci N, Mathew J, Emrence Z, Azakli H, Cosan F, Cakar A, Parlak M, Kursun O. Infect Genet Evol. 2012 Oct;12(7):1349-54. doi: 10.1016/j.meegid.2012.05.001. Epub 2012 May 14. PubMed |
Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFbeta tumor suppressor signaling pathways. Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, de vere White RW, Farnham PJ, Zern M. Mol Cancer Res. 2012 Jul;10(7):979-91. doi: 10.1158/1541-7786.MCR-11-0421. Epub 2012 May 23. PubMed |
Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors. Munoz P, Toscano MG, Real PJ, Benabdellah K, Cobo M, Bueno C, Ramos-Mejia V, Menendez P, Anderson P, Martin F. PLoS One. 2012;7(6):e39091. doi: 10.1371/journal.pone.0039091. Epub 2012 Jun 14. PubMed |
Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms. Nitta T, Lee S, Ha D, Arias M, Kozak CA, Fan H. Retrovirology. 2012 Jul 24;9:58. doi: 10.1186/1742-4690-9-58. PubMed |
Mechanism of capsaicin receptor TRPV1-mediated toxicity in pain-sensing neurons focusing on the effects of Na(+)/Ca(2+) fluxes and the Ca(2+)-binding protein calretinin. Pecze L, Blum W, Schwaller B. Biochim Biophys Acta. 2013 Jul;1833(7):1680-91. doi: 10.1016/j.bbamcr.2012.08.018. Epub 2012 Sep 5. PubMed |
Vascular endothelial growth factor-dependent spinogenesis underlies antidepressant-like effects of enriched environment. Huang YF, Yang CH, Huang CC, Hsu KS. J Biol Chem. 2012 Nov 30;287(49):40938-55. doi: 10.1074/jbc.M112.392076. Epub 2012 Oct 16. PubMed |
Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting. Hertz MI, Landry DM, Willis AE, Luo G, Thompson SR. Mol Cell Biol. 2013 Mar;33(5):1016-26. doi: 10.1128/MCB.00879-12. Epub 2012 Dec 28. PubMed |
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. Ruiz S, Gore A, Li Z, Panopoulos AD, Montserrat N, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Scholer HR, Zhang K, Izpisua Belmonte JC. Nat Commun. 2013;4:1382. doi: 10.1038/ncomms2381. PubMed |
OLA1 protects cells in heat shock by stabilizing HSP70. Mao RF, Rubio V, Chen H, Bai L, Mansour OC, Shi ZZ. Cell Death Dis. 2013 Feb 14;4:e491. doi: 10.1038/cddis.2013.23. PubMed |
Genetic manipulation of keratinocyte stem cells with lentiviral vectors. Yasuda M, Claypool DJ, Guevara E, Roop DR, Chen J. Methods Mol Biol. 2013;989:143-51. doi: 10.1007/978-1-62703-330-5_12. PubMed |
Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency. Barrero MJ, Sese B, Kuebler B, Bilic J, Boue S, Marti M, Izpisua Belmonte JC. Cell Rep. 2013 Apr 25;3(4):1005-11. doi: 10.1016/j.celrep.2013.02.029. Epub 2013 Mar 28. PubMed |
Calretinin is essential for mesothelioma cell growth/survival in vitro: a potential new target for malignant mesothelioma therapy? Blum W, Schwaller B. Int J Cancer. 2013 Nov;133(9):2077-88. doi: 10.1002/ijc.28218. Epub 2013 Jul 9. PubMed |
Translational control of Nrf2 within the open reading frame. Perez-Leal O, Barrero CA, Merali S. Biochem Biophys Res Commun. 2013 Jul 19;437(1):134-9. doi: 10.1016/j.bbrc.2013.06.052. Epub 2013 Jun 24. PubMed |
SMYD2 is induced during cell differentiation and participates in early development. Sese B, Barrero MJ, Fabregat MC, Sander V, Izpisua Belmonte JC. Int J Dev Biol. 2013;57(5):357-64. doi: 10.1387/ijdb.130051ji. PubMed |
Identification of epithelial stromal interaction 1 as a novel effector downstream of Kruppel-like factor 8 in breast cancer invasion and metastasis. Li T, Lu H, Shen C, Lahiri SK, Wason MS, Mukherjee D, Yu L, Zhao J. Oncogene. 2014 Sep 25;33(39):4746-55. doi: 10.1038/onc.2013.415. Epub 2013 Oct 7. PubMed |
Doxycycline-regulated GDNF expression promotes axonal regeneration and functional recovery in transected peripheral nerve. Shakhbazau A, Mohanty C, Shcharbin D, Bryszewska M, Caminade AM, Majoral JP, Alant J, Midha R. J Control Release. 2013 Dec 28;172(3):841-51. doi: 10.1016/j.jconrel.2013.10.004. Epub 2013 Oct 17. PubMed |
Adherens junction formation inhibits lentivirus entry and gene transfer. Padmashali R, You H, Karnik N, Lei P, Andreadis ST. PLoS One. 2013 Nov 13;8(11):e79265. doi: 10.1371/journal.pone.0079265. eCollection 2013. PubMed |
The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling. Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F. J Biol Chem. 2014 Jan 17;289(3):1364-76. doi: 10.1074/jbc.M113.499194. Epub 2013 Dec 2. PubMed |
Human mesenchymal stromal cells modulate T-cell responses through TNF-alpha-mediated activation of NF-kappaB. Dorronsoro A, Ferrin I, Salcedo JM, Jakobsson E, Fernandez-Rueda J, Lang V, Sepulveda P, Fechter K, Pennington D, Trigueros C. Eur J Immunol. 2014 Feb;44(2):480-8. doi: 10.1002/eji.201343668. Epub 2013 Dec 4. PubMed |
Identification of the NF-kappaB inhibitor A20 as a key regulator for human adipogenesis. Dorronsoro A, Lang V, Jakobsson E, Ferrin I, Salcedo JM, Fernandez-Rueda J, Fechter K, Rodriguez MS, Trigueros C. Cell Death Dis. 2013 Dec 19;4:e972. doi: 10.1038/cddis.2013.494. PubMed |
Visualizing of signaling proteins on endosomes utilizing knockdown and reconstitution approach. Jeoung M, Galperin E. Methods Enzymol. 2014;534:47-63. doi: 10.1016/B978-0-12-397926-1.00003-2. PubMed |
Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification). Braun J, Misiak D, Busch B, Krohn K, Huttelmaier S. Nucleic Acids Res. 2014 Apr;42(8):e66. doi: 10.1093/nar/gku127. Epub 2014 Feb 7. PubMed |
PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons. Yang DJ, Wang XL, Ismail A, Ashman CJ, Valori CF, Wang G, Gao S, Higginbottom A, Ince PG, Azzouz M, Xu J, Shaw PJ, Ning K. Cell Death Dis. 2014 Feb 27;5:e1096. doi: 10.1038/cddis.2014.55. PubMed |
Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Tiemann U, Marthaler AG, Adachi K, Wu G, Fischedick GU, Arauzo-Bravo MJ, Scholer HR, Tapia N. Stem Cell Reports. 2014 Feb 20;2(3):351-65. doi: 10.1016/j.stemcr.2014.01.005. eCollection 2014 Mar 11. PubMed |
Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasis. Huang Z, Tan N, Guo W, Wang L, Li H, Zhang T, Liu X, Xu Q, Li J, Guo Z. PLoS One. 2014 Apr 4;9(4):e91596. doi: 10.1371/journal.pone.0091596. eCollection 2014. PubMed |
Aligned collagen-GAG matrix as a 3D substrate for Schwann cell migration and dendrimer-based gene delivery. Shakhbazau A, Archibald SJ, Shcharbin D, Bryszewska M, Midha R. J Mater Sci Mater Med. 2014 Aug;25(8):1979-89. doi: 10.1007/s10856-014-5224-2. Epub 2014 May 7. PubMed |
Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space. Pruessmeyer J, Hess FM, Alert H, Groth E, Pasqualon T, Schwarz N, Nyamoya S, Kollert J, van der Vorst E, Donners M, Martin C, Uhlig S, Saftig P, Dreymueller D, Ludwig A. Blood. 2014 Jun 26;123(26):4077-88. doi: 10.1182/blood-2013-09-511543. Epub 2014 May 15. PubMed |
Presynaptic clathrin levels are a limiting factor for synaptic transmission. Lopez-Murcia FJ, Royle SJ, Llobet A. J Neurosci. 2014 Jun 18;34(25):8618-29. doi: 10.1523/JNEUROSCI.5081-13.2014. PubMed |
Human somatic cell mutagenesis creates genetically tractable sarcomas. Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang QL, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Izsvak Z, Lupien M, Mak TW, Khokha R. Nat Genet. 2014 Sep;46(9):964-72. doi: 10.1038/ng.3065. Epub 2014 Aug 17. PubMed |
MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival. Solari V, Borriello L, Turcatel G, Shimada H, Sposto R, Fernandez GE, Asgharzadeh S, Yates EA, Turnbull JE, DeClerck YA. Cancer Res. 2014 Nov 1;74(21):5999-6009. doi: 10.1158/0008-5472.CAN-13-2513. Epub 2014 Aug 27. PubMed |
Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H. Nat Commun. 2014 Sep 11;5:4839. doi: 10.1038/ncomms5839. PubMed |
Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells.
Zheng Q, Cai X, Tan MH, Schaffert S, Arnold CP, Gong X, Chen CZ, Huang S.
Biotechniques. 2014 Sep 1;57(3):115-24. doi: 10.2144/000114196. eCollection 2014.
PubMed
Associated Plasmids |
CERS2 suppresses tumor cell invasion and is associated with decreased V-ATPase and MMP-2/MMP-9 activities in breast cancer. Fan SH, Wang YY, Lu J, Zheng YL, Wu DM, Zhang ZF, Shan Q, Hu B, Li MQ, Cheng W. J Cell Biochem. 2015 Apr;116(4):502-13. doi: 10.1002/jcb.24978. PubMed |
Cartilage repair using human embryonic stem cell-derived chondroprogenitors. Cheng A, Kapacee Z, Peng J, Lu S, Lucas RJ, Hardingham TE, Kimber SJ. Stem Cells Transl Med. 2014 Nov;3(11):1287-94. doi: 10.5966/sctm.2014-0101. Epub 2014 Oct 1. PubMed |
Universal real-time PCR-based assay for lentiviral titration. Barczak W, Suchorska W, Rubis B, Kulcenty K. Mol Biotechnol. 2015 Feb;57(2):195-200. doi: 10.1007/s12033-014-9815-4. PubMed |
Characterization and modeling of Ca(2+) oscillations in mouse primary mesothelial cells. Pecze L, Schwaller B. Biochim Biophys Acta. 2015 Mar;1854(3):632-45. doi: 10.1016/j.bbamcr.2014.12.025. Epub 2014 Dec 30. PubMed |
CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCgamma1 activation: evidence from mice and humans. Martinez-Torres AC, Quiney C, Attout T, Boullet H, Herbi L, Vela L, Barbier S, Chateau D, Chapiro E, Nguyen-Khac F, Davi F, Le Garff-Tavernier M, Moumne R, Sarfati M, Karoyan P, Merle-Beral H, Launay P, Susin SA. PLoS Med. 2015 Mar 3;12(3):e1001796. doi: 10.1371/journal.pmed.1001796. eCollection 2015 Mar. PubMed |
Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape. Gavilan MP, Arjona M, Zurbano A, Formstecher E, Martinez-Morales JR, Bornens M, Rios RM. PLoS Biol. 2015 Mar 12;13(3):e1002087. doi: 10.1371/journal.pbio.1002087. eCollection 2015 Mar. PubMed |
Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity. Baschieri F, Uetz-von Allmen E, Legler DF, Farhan H. Cell Cycle. 2015;14(8):1139-47. doi: 10.1080/15384101.2015.1007771. PubMed |
MicroRNA-200c-141 and Np63 are required for breast epithelial differentiation and branching morphogenesis. Hilmarsdottir B, Briem E, Sigurdsson V, Franzdottir SR, Ringner M, Arason AJ, Bergthorsson JT, Magnusson MK, Gudjonsson T. Dev Biol. 2015 Jul 15;403(2):150-61. doi: 10.1016/j.ydbio.2015.05.007. Epub 2015 May 9. PubMed |
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert WA, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens GK, Tallquist MD, Quertermous T. PLoS Genet. 2015 May 28;11(5):e1005155. doi: 10.1371/journal.pgen.1005155. eCollection 2015 May. PubMed |
Use of Ferritin Expression, Regulated by Neural Cell-Specific Promoters in Human Adipose Tissue-Derived Mesenchymal Stem Cells, to Monitor Differentiation with Magnetic Resonance Imaging In Vitro. Song C, Wang J, Mo C, Mu S, Jiang X, Li X, Zhong S, Zhao Z, Zhou G. PLoS One. 2015 Jul 15;10(7):e0132480. doi: 10.1371/journal.pone.0132480. eCollection 2015. PubMed |
Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. Aime P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. J Neurosci. 2015 Jul 29;35(30):10731-49. doi: 10.1523/JNEUROSCI.0614-15.2015. PubMed |
CFTR inactivation by lentiviral vector-mediated RNA interference and CRISPR-Cas9 genome editing in human airway epithelial cells. Bellec J, Bacchetta M, Losa D, Anegon I, Chanson M, Nguyen TH. Curr Gene Ther. 2015;15(5):447-59. PubMed |
OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Chen H, Song R, Wang G, Ding Z, Yang C, Zhang J, Zeng Z, Rubio V, Wang L, Zu N, Weiskoff AM, Minze LJ, Jeyabal PV, Mansour OC, Bai L, Merrick WC, Zheng S, Shi ZZ. Sci Rep. 2015 Aug 18;5:13241. doi: 10.1038/srep13241. PubMed |
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane. Loregger A, Grandl M, Mejias-Luque R, Allgauer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M. Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757. PubMed |
Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERS. Pecze L, Blum W, Schwaller B. J Biol Chem. 2015 Nov 20;290(47):28214-30. doi: 10.1074/jbc.M115.663179. Epub 2015 Sep 22. PubMed |
OTX2 is a therapeutic target for retinoblastoma and may function as a common factor between C-MYC, CRX, and phosphorylated RB pathways. Li J, Di C, Jing J, Di Q, Nakhla J, Adamson DC. Int J Oncol. 2015 Nov;47(5):1703-10. doi: 10.3892/ijo.2015.3179. Epub 2015 Sep 23. PubMed |
Hydrogel biophysical properties instruct coculture-mediated osteogenic potential. Murphy KC, Stilhano RS, Mitra D, Zhou D, Batarni S, Silva EA, Leach JK. FASEB J. 2016 Jan;30(1):477-86. doi: 10.1096/fj.15-279984. Epub 2015 Oct 6. PubMed |
Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells. Henzi T, Schwaller B. PLoS One. 2015 Nov 5;10(11):e0142005. doi: 10.1371/journal.pone.0142005. eCollection 2015. PubMed |
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, Berger H, Mollenkopf HJ, Mangler M, Sehouli J, Fotopoulou C, Meyer TF. Nat Commun. 2015 Dec 8;6:8989. doi: 10.1038/ncomms9989. PubMed |
Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration. Blum W, Pecze L, Felley-Bosco E, Schwaller B. Respir Res. 2015 Dec 22;16:153. doi: 10.1186/s12931-015-0311-6. PubMed |
Inhibition of Canonical NF-kappaB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction. Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D. Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934. PubMed |
Oncogenic CARMA1 couples NF-kappaB and beta-catenin signaling in diffuse large B-cell lymphomas. Bognar MK, Vincendeau M, Erdmann T, Seeholzer T, Grau M, Linnemann JR, Ruland J, Scheel CH, Lenz P, Ott G, Lenz G, Hauck SM, Krappmann D. Oncogene. 2016 Jan 18. doi: 10.1038/onc.2015.493. PubMed |
Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma. Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P. J Invest Dermatol. 2016 May;136(5):967-77. doi: 10.1016/j.jid.2016.01.020. Epub 2016 Jan 30. PubMed |
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