pCMV6M-Pak1 K299R Citations (10)

Originally described in: Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.
Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J Curr Biol. 1997 Mar 1. 7(3):202-10. PubMed Journal

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Articles Citing pCMV6M-Pak1 K299R

Articles
COX-2 promoter activation by AT1R-Gq-PAK-p38beta signaling in intestinal epithelial cells. Pham H, Vincenti R, Slice LW. Biochim Biophys Acta. 2008 Jun-Jul;1779(6-7):408-13. doi: 10.1016/j.bbagrm.2008.05.004. Epub 2008 May 13. PubMed
Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin. Venkatareddy M, Cook L, Abuarquob K, Verma R, Garg P. PLoS One. 2011;6(12):e28710. doi: 10.1371/journal.pone.0028710. Epub 2011 Dec 14. PubMed
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase. Barrows D, Schoenfeld SM, Hodakoski C, Silkov A, Honig B, Couvillon A, Shymanets A, Nurnberg B, Asara JM, Parsons R. J Biol Chem. 2015 Nov 27;290(48):28915-31. doi: 10.1074/jbc.M115.668244. Epub 2015 Oct 5. PubMed
Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway. Yeh CW, Hsu LS. Mol Neurobiol. 2015 Dec 3. PubMed
Neuronal Filopodium Formation Induced by the Membrane Glycoprotein M6a (Gpm6a) is Facilitated by Coronin-1a, Rac1 and p21-Activated Kinase 1 (Pak1). Alvarez Julia A, Frasch AC, Fuchsova B. J Neurochem. 2016 Jan 26. doi: 10.1111/jnc.13552. PubMed
PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1. Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY. Hum Mol Genet. 2018 Aug 15;27(16):2863-2873. doi: 10.1093/hmg/ddy200. PubMed
PAK1 Regulates MEC-17 Acetyltransferase Activity and Microtubule Acetylation during Proplatelet Extension. van Dijk J, Bompard G, Rabeharivelo G, Cau J, Delsert C, Morin N. Int J Mol Sci. 2020 Oct 13;21(20):7531. doi: 10.3390/ijms21207531. PubMed
PAK1 Positively Regulates Oligodendrocyte Morphology and Myelination. Brown TL, Hashimoto H, Finseth LT, Wood TL, Macklin WB. J Neurosci. 2021 Mar 3;41(9):1864-1877. doi: 10.1523/JNEUROSCI.0229-20.2021. Epub 2021 Jan 21. PubMed
Vimentin tunes cell migration on collagen by controlling beta1 integrin activation and clustering. Ostrowska-Podhorodecka Z, Ding I, Lee W, Tanic J, Abbasi S, Arora PD, Liu RS, Patteson AE, Janmey PA, McCulloch CA. J Cell Sci. 2021 Mar 29;134(6). pii: jcs.254359. doi: 10.1242/jcs.254359. PubMed
A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling. Davidson A, Tyler J, Hume P, Singh V, Koronakis V. PLoS Pathog. 2021 Aug 30;17(8):e1009902. doi: 10.1371/journal.ppat.1009902. eCollection 2021 Aug. PubMed

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