pCMV6M-PAK1 T423E Citations (16)
Originally described in: Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J Curr Biol. 1997 Mar 1. 7(3):202-10. PubMed Journal
Articles Citing pCMV6M-PAK1 T423E
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| COX-2 promoter activation by AT1R-Gq-PAK-p38beta signaling in intestinal epithelial cells. Pham H, Vincenti R, Slice LW. Biochim Biophys Acta. 2008 Jun-Jul;1779(6-7):408-13. doi: 10.1016/j.bbagrm.2008.05.004. Epub 2008 May 13. PubMed |
| PAK1 is involved in sensing the orientation of collagen stiffness gradients in mouse fibroblasts. Pinto VI, Mohammadi H, Lee WS, Cheung A, McCulloch CA. Biochim Biophys Acta. 2015 May 27. pii: S0167-4889(15)00173-1. doi: 10.1016/j.bbamcr.2015.05.019. PubMed |
| Integrin-alpha10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma. Okada T, Lee AY, Qin LX, Agaram N, Mimae T, Shen Y, O'Connor R, Lopez-Lago MA, Craig A, Miller ML, Agius P, Molinelli E, Socci ND, Crago AM, Shima F, Sander C, Singer S. Cancer Discov. 2016 Oct;6(10):1148-1165. doi: 10.1158/2159-8290.CD-15-1481. Epub 2016 Aug 30. PubMed |
| P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells. Babagana M, Johnson S, Slabodkin H, Bshara W, Morrison C, Kandel ES. Mol Carcinog. 2017 Jan 4. doi: 10.1002/mc.22611. PubMed |
| Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. Chang JK, Ni Y, Han L, Sinnett-Smith J, Jacamo R, Rey O, Young SH, Rozengurt E. J Biol Chem. 2017 Jun 9;292(23):9523-9539. doi: 10.1074/jbc.M116.771394. Epub 2017 Apr 13. PubMed |
| beta1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin. Sabra H, Brunner M, Mandati V, Wehrle-Haller B, Lallemand D, Ribba AS, Chevalier G, Guardiola P, Block MR, Bouvard D. J Biol Chem. 2017 Nov 24;292(47):19179-19197. doi: 10.1074/jbc.M117.808063. Epub 2017 Sep 29. PubMed |
| Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer. Hodakoski C, Hopkins BD, Zhang G, Su T, Cheng Z, Morris R, Rhee KY, Goncalves MD, Cantley LC. Cancers (Basel). 2019 Jan 2;11(1). pii: cancers11010037. doi: 10.3390/cancers11010037. PubMed |
| Periostin/beta1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization. Ghatak S, Misra S, Moreno-Rodrigue RA, Hascall VC, Leone GW, Markwald RR. Biochim Biophys Acta Gen Subj. 2019 May;1863(5):813-829. doi: 10.1016/j.bbagen.2018.12.015. Epub 2019 Feb 10. PubMed |
| Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5. Feng X, Zhang H, Meng L, Song H, Zhou Q, Qu C, Zhao P, Li Q, Zou C, Liu X, Zhang Z. Autophagy. 2021 Mar;17(3):723-742. doi: 10.1080/15548627.2020.1731266. Epub 2020 Mar 18. PubMed |
| PAK1 Positively Regulates Oligodendrocyte Morphology and Myelination. Brown TL, Hashimoto H, Finseth LT, Wood TL, Macklin WB. J Neurosci. 2021 Mar 3;41(9):1864-1877. doi: 10.1523/JNEUROSCI.0229-20.2021. Epub 2021 Jan 21. PubMed |
| Vimentin tunes cell migration on collagen by controlling beta1 integrin activation and clustering. Ostrowska-Podhorodecka Z, Ding I, Lee W, Tanic J, Abbasi S, Arora PD, Liu RS, Patteson AE, Janmey PA, McCulloch CA. J Cell Sci. 2021 Mar 29;134(6). pii: jcs.254359. doi: 10.1242/jcs.254359. PubMed |
| Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia. Huang N, Li S, Xie Y, Han Q, Xu XM, Sheng ZH. Curr Biol. 2021 Jul 26;31(14):3098-3114.e7. doi: 10.1016/j.cub.2021.04.079. Epub 2021 Jun 3. PubMed |
| Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction. Misra S, Ghatak S, Moreno-Rodriguez RA, Norris RA, Hascall VC, Markwald RR. Front Cell Dev Biol. 2021 Jun 3;9:649862. doi: 10.3389/fcell.2021.649862. eCollection 2021. PubMed |
| A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling. Davidson A, Tyler J, Hume P, Singh V, Koronakis V. PLoS Pathog. 2021 Aug 30;17(8):e1009902. doi: 10.1371/journal.ppat.1009902. eCollection 2021 Aug. PubMed |
| Mechanism by Which PF-3758309, a Pan Isoform Inhibitor of p21-Activated Kinases, Blocks Reactivation of HIV-1 Latency. Vargas B, Boslett J, Yates N, Sluis-Cremer N. Biomolecules. 2023 Jan 4;13(1):100. doi: 10.3390/biom13010100. PubMed |
| Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions. Wang Y, Kim B, Gong S, Park J, Zhu M, Wong EM, Park AY, Chernoff J, Guo F. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591153. doi: 10.1101/2024.04.26.591153. PubMed |
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