Orai1 Citations (7)
Originally described in: A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A Nature. 2006 May 11. 441(7090):179-85. PubMed Journal
Articles Citing Orai1
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STIM1- and Orai1-dependent store-operated calcium entry regulates human myoblast differentiation. Darbellay B, Arnaudeau S, König S, Jousset H, Bader C, Demaurex N, Bernheim L. J Biol Chem. 2009 Feb 20. 284(8):5370-80. PubMed |
Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry. Pozo-Guisado E, Campbell DG, Deak M, Alvarez-Barrientos A, Morrice NA, Alvarez IS, Alessi DR, Martin-Romero FJ. J Cell Sci. 2010 Sep 15;123(Pt 18):3084-93. doi: 10.1242/jcs.067215. Epub 2010 Aug 24. PubMed |
Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes. Li H, Ding X, Lopez JR, Takeshima H, Ma J, Allen PD, Eltit JM. J Biol Chem. 2010 Dec 10;285(50):39171-9. doi: 10.1074/jbc.M110.149690. Epub 2010 Oct 11. PubMed |
Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. FASEB J. 2013 Mar;27(3):991-1000. doi: 10.1096/fj.12-218354. Epub 2012 Nov 16. PubMed |
STIM1L traps and gates Orai1 channels without remodeling the cortical ER. Sauc S, Bulla M, Nunes P, Orci L, Marchetti A, Antigny F, Bernheim L, Cosson P, Frieden M, Demaurex N. J Cell Sci. 2015 Apr 15;128(8):1568-79. doi: 10.1242/jcs.164228. Epub 2015 Mar 3. PubMed |
Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels. Tsujikawa H, Yu AS, Xie J, Yue Z, Yang W, He Y, Yue L. Sci Rep. 2015 Nov 18;5:16747. doi: 10.1038/srep16747. PubMed |
SPLUNC1 is a negative regulator of the Orai1 Ca(2+) channel. Wu T, Goriounova AS, Worthington EN, Wrennall JA, Ghosh A, Ahmad S, Flori Sassano M, Tarran R. Physiol Rep. 2022 May;10(10):e15306. doi: 10.14814/phy2.15306. PubMed |
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