p3xFLAG-ATF6 Citations (18)
Originally described in: The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi.Chen X, Shen J, Prywes R J Biol Chem. 2002 Apr 12. 277(15):13045-52. PubMed Journal
Articles Citing p3xFLAG-ATF6
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Assessment of endoplasmic reticulum stress and the unfolded protein response in endothelial cells. Witte I, Horke S. Methods Enzymol. 2011;489:127-46. doi: 10.1016/B978-0-12-385116-1.00008-X. PubMed |
Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells. Witte I, Altenhofer S, Wilgenbus P, Amort J, Clement AM, Pautz A, Li H, Forstermann U, Horke S. Cell Death Dis. 2011 Jan 13;2:e112. doi: 10.1038/cddis.2010.91. PubMed |
A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. Dodding MP, Mitter R, Humphries AC, Way M. EMBO J. 2011 Nov 16;30(22):4523-38. doi: 10.1038/emboj.2011.326. PubMed |
Metformin differentially activates ER stress signaling pathways without inducing apoptosis. Quentin T, Steinmetz M, Poppe A, Thoms S. Dis Model Mech. 2012 Mar;5(2):259-69. doi: 10.1242/dmm.008110. Epub 2011 Nov 22. PubMed |
A functional link between the co-translational protein translocation pathway and the UPR. Plumb R, Zhang ZR, Appathurai S, Mariappan M. Elife. 2015 May 20;4. doi: 10.7554/eLife.07426. PubMed |
VAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis. Ernst WL, Shome K, Wu CC, Gong X, Frizzell RA, Aridor M. J Biol Chem. 2016 Mar 4;291(10):5206-20. doi: 10.1074/jbc.M115.692749. Epub 2016 Jan 6. PubMed |
Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2. El Karoui K, Viau A, Dellis O, Bagattin A, Nguyen C, Baron W, Burtin M, Broueilh M, Heidet L, Mollet G, Druilhe A, Antignac C, Knebelmann B, Friedlander G, Bienaime F, Gallazzini M, Terzi F. Nat Commun. 2016 Jan 20;7:10330. doi: 10.1038/ncomms10330. PubMed |
Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. Cagalinec M, Liiv M, Hodurova Z, Hickey MA, Vaarmann A, Mandel M, Zeb A, Choubey V, Kuum M, Safiulina D, Vasar E, Veksler V, Kaasik A. PLoS Biol. 2016 Jul 19;14(7):e1002511. doi: 10.1371/journal.pbio.1002511. eCollection 2016 Jul. PubMed |
Disulfide bond disrupting agents activate the unfolded protein response in EGFR- and HER2-positive breast tumor cells. Ferreira RB, Wang M, Law ME, Davis BJ, Bartley AN, Higgins PJ, Kilberg MS, Santostefano KE, Terada N, Heldermon CD, Castellano RK, Law BK. Oncotarget. 2017 Apr 25;8(17):28971-28989. doi: 10.18632/oncotarget.15952. PubMed |
Disrupted ER-to-Golgi Trafficking Underlies Anti-HIV Drugs and Alcohol-Induced Cellular Stress and Hepatic Injury. Han H, He Y, Hu J, Lau R, Lee H, Ji C. Hepatol Commun. 2017 Apr;1(2):122-139. doi: 10.1002/hep4.1030. Epub 2017 Mar 27. PubMed |
The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro. Park JW, Choi WG, Lee PJ, Chung SW, Kim BS, Chung HT, Cho S, Kim JH, Kang BH, Kim H, Kim HP, Back SH. Acta Pharmacol Sin. 2017 Nov;38(11):1486-1500. doi: 10.1038/aps.2017.106. Epub 2017 Aug 10. PubMed |
GIV/Girdin promotes cell survival during endoplasmic reticulum stress. Nguyen P, Calderon R, Rodriguez-Ledezma Y, Araujo K, Bhandari D. Mol Cell Biochem. 2019 Mar;453(1-2):79-88. doi: 10.1007/s11010-018-3433-6. Epub 2018 Aug 25. PubMed |
The p38-activated ER stress-ATF6alpha axis mediates cellular senescence. Kim HS, Kim Y, Lim MJ, Park YG, Park SI, Sohn J. FASEB J. 2019 Feb;33(2):2422-2434. doi: 10.1096/fj.201800836R. Epub 2018 Sep 27. PubMed |
Resveratrol Ameliorates Lipid Droplet Accumulation in Liver Through a SIRT1/ ATF6-Dependent Mechanism. Zhou R, Yi L, Ye X, Zeng X, Liu K, Qin Y, Zhang Q, Mi M. Cell Physiol Biochem. 2018;51(5):2397-2420. doi: 10.1159/000495898. Epub 2018 Dec 11. PubMed |
Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication. Rohde C, Becker S, Krahling V. Emerg Microbes Infect. 2019;8(1):1300-1313. doi: 10.1080/22221751.2019.1659552. PubMed |
A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems. Sicari D, Delaunay-Moisan A, Combettes L, Chevet E, Igbaria A. FEBS J. 2020 Jan;287(1):27-42. doi: 10.1111/febs.15107. Epub 2019 Nov 11. PubMed |
The Ca(2+) -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6. Parks SZ, Gao T, Jimenez Awuapura N, Ayathamattam J, Chabosseau PL, Kalvakolanu DV, Valdivia HH, Rutter GA, Leclerc I. FEBS Lett. 2021 Jul;595(13):1782-1796. doi: 10.1002/1873-3468.14101. Epub 2021 May 24. PubMed |
In vivo screen identifies a SIK inhibitor that induces beta cell proliferation through a transient UPR. Charbord J, Ren L, Sharma RB, Johansson A, Agren R, Chu L, Tworus D, Schulz N, Charbord P, Stewart AF, Wang P, Alonso LC, Andersson O. Nat Metab. 2021 May;3(5):682-700. doi: 10.1038/s42255-021-00391-x. Epub 2021 May 20. PubMed |
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